This work presents a technique for shape modelling of cylindrical and spherical tablets subject to compression. This technique is based on the use of partial differential equations (PDEs), the biharmonic equation in particular. The deformation of the compressed elastic-plastic tablet of both shapes was obtained using the existing contact models found in literature. The mathematical properties of the biharmonic equation have been exploited to achieve simple mathematical expressions characterising the shape of the distorted tablet. Thus, the height, radius and contact area of both configurations due to uniaxial compression are represented by analytic expressions relating the coefficients associated with the solution of the biharmonic equation. The results obtained from the PDE-based simulation are compared with the theoretical ones. It is found that the analytic solution of the elliptic PDE can be utilised to represent the physical changes of the deformed object.

This paper considers a study of the thermo-elastic behaviour of a disc brake during heavy braking. The work is concerned with working towards developing design advice that provides uniform heating of the disc, and equally important, even dissipation of heat from the disc blade. The material presented emanates from a combination of modeling, on-vehicle testing but mainly laboratory observations and subsequent investigations. The experimental work makes use of a purpose built high speed brake dynamometer which incorporates the full vehicle suspension for controlled simulation of the brake and vehicle operating conditions. Advanced instrumentation allows dynamic measurement of brake pressure fluctuations, disc surface temperature and discrete vibration measurements. Disc run-out measurements using non-contacting displacement transducers show the disc taking up varying orders of deformation ranging from first to third order during high speed testing. This surface interrogation during braking identifies disc deformation including disc warping, 'ripple' and the effects of 'hot spotting'. The mechanical measurements are complemented by thermal imaging of the brake, these images showing the vane and vent patterns on the surface of the disc. The results also include static surface scanning, or geometry analysis, of the disc which is carried out at appropriate stages during testing. The work includes stress relieving of finished discs and subsequent dynamometer testing. This identifies that in-service stress relieving, due to high heat input during braking, is a strong possibility for the cause of disc 'warping'. It is also seen that an elastic wave is established during a braking event, the wave disappearing on release of the brake.

No / Bone morphogenetic protein (BMP) signaling plays a key role in the control of skin development and postnatal remodeling by regulating keratinocyte proliferation, differentiation, and apoptosis. To study the role of BMPs in wound-induced epidermal repair, we used transgenic mice overexpressing the BMP downstream component Smad1 under the control of a K14 promoter as an in vivo model, as well as ex vivo and in vitro assays. K14-caSmad1 (transgenic mice overexpressing a constitutively active form of Smad1 under K14 promoter) mice exhibited retarded wound healing associated with significant inhibition of proliferation and increased apoptosis in healing wound epithelium. Furthermore, microarray and quantitative real-time reverse-transcriptase-PCR (qRT-PCR) analyses revealed decreased expression of a number of cytoskeletal/cell motility-associated genes including wound-associated keratins (Krt16, Krt17) and Myosin VA (Myo5a), in the epidermis of K14-caSmad1 mice versus wild-type (WT) controls during wound healing. BMP treatment significantly inhibited keratinocyte migration ex vivo, and primary keratinocytes of K14-caSmad1 mice showed retarded migration compared with WT controls. Finally, small interfering RNA (siRNA)-mediated silencing of BMPR-1B in primary mouse keratinocytes accelerated cell migration and was associated with increased expression of Krt16, Krt17, and Myo5a compared with controls. Thus, this study demonstrates that BMPs inhibit keratinocyte proliferation, cytoskeletal organization, and migration in regenerating skin epithelium during wound healing, and raises a possibility for using BMP antagonists for the management of chronic wounds.

No / The growing demand for high-quality middle distillates is increasing worldwide, whereas the demand for low-value oil products, such as heavy oils and residues, is decreasing. Thus, maximizing the production of more liquid distillates of very high quality is of immediate interest to refiners. At the same time, environmental legislation has led to more strict specifications of petroleum derivatives. Hydrotreatment (HDT) of crude oil is one of the most challenging tasks in the petroleum refining industry, which has not been reported widely in the literature. In this work, crude oil was hydrotreated upon a commercial cobalt¿molybdenum on alumina (Co¿Mo/¿-Al2O3) catalyst presulfided at specified conditions. Detailed pilot-plant experiments were conducted in a continuous-flow isothermal trickle-bed reactor (TBR), and the main hydrotreating reactions were hydrodesulfurization (HDS), hydrodenitrogenation (HDN), hydrodeasphaltenization (HDAs), and hydrodemetallization (HDM), which includes hydrodevanadization (HDV) and hydrodenickelation (HDNi). The reaction temperature (T), the hydrogen pressure (P), and the liquid hourly space velocity (LHSV) were varied with certain ranges, with constant hydrogen to oil (H2/Oil) ratio. The effects of T, P, and LHSV on the conversion of sulfur, nitrogen, vanadium, nickel, and asphaltene were studied. The results showed that high T and P and low LHSV in HDS, HDN, HDV, HDNi, and HDAs of crude oil improve the sulfur (S), nitrogen (N), metals [vanadium (V) and nickel (Ni)], and asphaltene (Asph) conversion. The hydrotreated crude oil has been distilled into the following fractions: light naphtha (LN), heavy naphtha (HN), heavy kerosene (HK), light gas oil (LGO), and reduced crude residue (RCR), to compare the yield of these fractions produced by distillation after the HDT process to those produced by conventional methods (i.e., HDT of each fraction separately after the distillation). The yield of the middle distillate showed greater yield compared to the middle distillate produced by conventional methods. The properties of RCR produced using both methods are also discussed.

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No / The Politics of Truth Management in Saudi Arabia argues that there are two interrelated notions which articulate the ways in which ‘truth’ is conceptualised in Islam. One, at macro level, constitutes the trans-historical foundational principles of the religion, a set of engrained beliefs, which establish the ‘finality’, and ‘oneness’ of Islam in relation to other competing narratives. The other, at a micro level, takes place internally to find ‘truth’ within the ‘truth’. Unlike Islamic truth at the macro level, which is entrenched, the Islamic truth at the micro level refers to the various attempts by different agencies to claim to have found the ‘truth’ within the ‘truth’. 　Wahhabism, which is the product of an eighteenth century revivalist movement, is portrayed as the most ‘authentic’ reading of Islam. It is seen as the raison d'être for the prevailing political mechanism in the country and is introduced as an example of truth management at the micro level. Arguing that truth is not born in a power vacuum and often its construction and institutionalisation signify domination in one way or another, this book will be of interest to students of Religion, Politics, and Saudi Politics more specifically.

The architect operates in both physical and spatial media. When in the presence of architectural form, an observer exists within the volume defined by surface and within the context of constructive material. At once the presence of architecture is imbued through spatial awareness, texture, sound, weight, light, shadow; material and volume modulate the senses to create the architectural experience. Montessori education is a pedagogy based on the development of a child's natural curiosity and intuition. The Guides lead rather than teach, encouraging the student to explore through activity. The student's intuitive exploration cannot be dictated or controlled by environment; the architect's role in education, therefore, is to work within his or her craft to create an "experiential architecture", one that utilizes the context of pedagogy, site, and material to develop a series of spaces to inspire within the individual a feeling unique to each. The architect must understand the nature of material, the way in which it wants to be used, to create an experience in which the architecture speaks of its making. The craft of building, then, becomes an architectural experience operating alongside the art of spatial composition. This school is the vehicle for exploring the dialogue between the spatiality and materiality of architecture. / Master of Architecture

This thesis explores form and flow of space through the program of a theatre and gallery. It studies the relation between a building and its surrounding landscape, in order to create public gathering spaces. It also deals with the question of scale and its reflection on how you feel the space. In this project, the building is an extension to the landscape where the ground becomes the roof, and where the boundaries of a space are blurred. The project is also a memorial for the 2011 and 2013 revolutions in Egypt. It is a place of memory but also a space to inspire future generations. In studying the relationship between two elements, model making and sketching were the primary means of generating the form. Then the design was advanced through a series of digital models and hand sketches. My drawings in general are a rational representation of the spaces. It deals with the sense, rather than the material aspect, of the space. / Master of Architecture

this house began as a desire to place a single floating mass on the horizon, but became an exploration of proportion, material, and volume, and how they relate to each other. / Master of Architecture

This thesis grew from a curiosity to understand monumentality, form, and design in a project that is rooted in constructional development. The program is a city hall in Rockville, Maryland, in the spirit of a basilica. A city hall should act as a room for the city. This is a place for public matters to be debated, people to meet others, events to be celebrated, and ideas to be discussed. / Master of Architecture