The astronomical exploration at energies between 30\,GeV and $\lesssim$\,350\,GeV was the main motivation for building the \MAGIC-telescope. With its 17\,m \diameter\ mirror it is the worldwide largest imaging air-Cherenkov telescope. It is located at the Roque de los Muchachos at the Canary island of San Miguel de La Palma at 28.8$^\circ$\,N, 17.8$^\circ$\,W, 2200\,m a.s.l. The telescope detects Cherenkov light produced by relativistic electrons and positrons in air showers initiated by cosmic gamma-rays. The imaging technique is used to powerfully reject the background due to hadronically induced air showers from cosmic rays. Their inverse power-law energy-distribution leads to an increase of the event rate with decreasing energy threshold. For \MAGIC this implies a trigger rate in the order of 250\,Hz, and a correspondingly large data stream to be recorded and analyzed. A robust analysis software package, including the general framework \MARS, was developed and commissioned to allow automation, necessary for data taken under variable observing conditions. Since many of the astronomical sources of high-energy radiation, in particular the enigmatic gamma-ray bursts, are of a transient nature, the telescope was designed to allow repositioning in several tens of seconds, keeping a tracking accuracy of $\lesssim\,$0.01$^\circ$. Employing a starguider, a tracking accuracy of $\lesssim\,$1.3\,minutes of arc was obtained. The main class of sources at very high gamma-ray energies, known from previous imaging air-Cherenkov telescopes, are Active Galactic Nuclei with relativistic jets, the so-called high-peaked Blazars. Their spectrum is entirely dominated by non-thermal emission, spanning more than 15 orders of magnitude in energy, from radio to gamma-ray energies. Predictions based on radiation models invoking a synchrotron self-Compton or hadronic origin of the gamma-rays suggest, that a fairly large number of them should be detectable by \MAGIC. Promising candidates have been chosen from existing compilations, requiring high (synchrotron) X-ray flux, assumed to be related to a high (possibly inverse-Compton) flux at GeV energies, and a low distance, in oder to avoid strong attenuation due to pair-production in interactions with low-energy photons from the extragalactic background radiation along the line of sight. Based on this selection the first \AGN, emitting gamma-rays at 100\,GeV, 1ES\,1218+304 at a redshift of $z=0.182$, was discovered, one of the two farthest known \AGN emitting in the TeV energy region. In this context, the automated analysis chain was successfully demonstrated. The source was observed in January 2005 during six moonless nights for 8.2\,h. At the same time the collaborating \KVA-telescope, located near the \MAGIC site, observed in the optical band. The lightcurve calculated showed no day-to-day variability and is compatible with a constant flux of $F($\,$>$\,$100\,\mbox{GeV})=(8.7\pm1.4) \cdot 10^{-7}\,\mbox{m}^{-2}\,\mbox{s}^{-1}$ within the statistical errors. A differential spectrum between 87\,GeV and 630\,GeV was calculated and is compatible with a power law of $F_E(E) = (8.1\pm 2.1) \cdot 10^{-7}(E/\mbox{250\,GeV})^{-3.0\pm0.4}\,\mbox{TeV}^{-1}\,\mbox{m}^{-2}\,\mbox{s}^{-1}$ within the statistical errors. The spectrum emitted by the source was obtained by taking into account the attenuation due to pair-production with photons of the extragalactic background at low photon energies. A homogeneous, one-zone synchrotron self-Compton model has been fitted to the collected multi-wavelength data. Using the simultaneous optical data, a best fit model could be obtained from which some physical properties of the emitting plasma could be inferred. The result was compared with the so-called {\em Blazar sequence}. / Die wesentliche Motivation zum Bau des \MAGIC-Teleskops war die Untersuchung astronomischer Objekte zwischen 30\,GeV und $\lesssim$\,350\,GeV. Mit einem 17\,m \diameter\ Spiegel ist es das weltweit gr"o"ste abbildende Luft-Cherenkov Teleskop. Es steht auf der Kanarischen Insel San Miguel de La Palma auf dem Roque de los Muchachos. Das Teleskop detektiert Cherenkov Licht von Elektronen und Positron aus Luftschauern, erzeugt von kosmischer Gammastrahlung. Die abbildende Technik ist das Hauptmerkmal einer guten Unterdr"uckung des Untergrundes, der haupts"achlich aus Luftschauern der kosmischen Strahlung besteht. Ihre Energieverteilung, beschrieben durch ein steil abfallendes Potenzgesetz, f"uhrt zu einem starken Anstieg der Ereignisrate bei sinkender Energieschwelle. F"ur \MAGIC bedeutet das Raten von etwa 250\,Hz, was zu einem gro"sen Datenstrom f"uhrt, der verarbeitet werden muss. Dazu wurde eine robuste Analyse Software, einschlie"slich des Grundger"ustes \MARS, entwickelt und ihre Anwendung automatisiert. Dies ist n"otig um wechselnde Beobachtungsbedingungen ber"ucksichtigen zu k"onnen. Da viele Quellen von Hochenergie Gammastrahlen, insbesondere die r"atselhaften {\em Gamma-Ray Bursts}, stark ver"anderliche Ph"anomene sind, wurde das Teleskop so ausgelegt, dass es Neuausrichtungen innerhalb weniger Sekunden erm"oglicht, und trotzdem eine Nachf"uhrgenauigkeit von $\lesssim\,$0.01$^\circ$ erreicht, die mit einem {\em Starguider} auf $\lesssim\,$1.3$'$ verbessert wird. %Dies wird erreicht durch den Vergleich %eines von einer \CCD-Kamera aufgenommenen Sternenfeldes mit dem %aus Sternenkatalogen berechneten. Die wichtigsten Quellen sehr hochenergetischer Gammastrahlung sind Aktive Galaktische Kerne mit relativistischen Jets, die sog.\ {\em high-peaked Blazars}. Ihr Spektrum erstreckt sich "uber mehr als 15 Gr"o"senordnungen, vom Radio- bis zum Gammabereich, und ist vollst"andig durch nicht-thermische Strahlung dominiert. Modelle, die {\em synchrotron selbst-Compton} Strahlung oder Strahlung aus hadroninduzierten Kaskaden zu Grunde legen, sagen voraus, dass eine gro"se Anzahl dieser Quellen von \MAGIC zu detektieren sein m"ussten. Vielversprechende Kandidaten wurden aus existierenden Katalogen ausgesucht mit der Anforderung eines gro"sen R"ontgenflusses (Synchrotronstrahlung), von dem erwartet wird, dass er einen gro"sen Fluss bei GeV-Energien zur Folge hat. Au"serdem wurden nur nahe Quellen ausgew"ahlt um nicht von der Abschw"achung des Flusses durch Paarbildung an der extragalaktischen Hintergrundstrahlung entlang der Sichtlinie betroffen zu sein. Basierend auf dieser Auswahl wurde zum ersten Mal Gammastrahlung von 100\,GeV bei einem \AGN (1ES\,1218+304,$z=0.182$) nachgewiesen. Hierbei wurde die automatische Analysekette erfolgreich demonstriert. Die Quelle wurde im Januar 2005 w"ahrend sechs mondloser N"achte 8.2 Stunden lang beobachtet. Zeitgleich wurden Daten im optischen Bereich vom mitarbeitenden \KVA-Teleskop aufgenommen. Die berechnete Lichtkurve ist innerhalb der statistischen Fehler mit einem konstanten Fluss von $F($\,$>$\,$100\,\mbox{GeV})=(8.7\pm1.4)\cdot 10^{-7}\,\mbox{m}^{-2}\,\mbox{s}^{-1}$ vertr"aglich. Das differentielle Spektrum wurde zwischen 87\,GeV und 630\,GeV bestimmt und ist innerhalb der statistischen Fehler mit einem Potenzgesetz $F_E(E)=(8.1\pm 2.1)\cdot10^{-7}\,(E/\mbox{250\,GeV})^{-3.0\pm0.4}\,\mbox{TeV}^{-1}\,\mbox{m}^{-2}\,\mbox{s}^{-1}$ vereinbar. Daraus wurde das von der Quelle emittierte Spektrum errechnet, indem die Paarbildung am extragalaktischen Hintergrund entlang der Sichtlinie ber"ucksichtigt wurde. An das resultierende Spektrum und weitere gesammelte Multiwellenl"angendaten wurde ein homogenes einzonen {\em synchrotron selbst-Compton} Modell angepasst. Unter Ber"ucksichtigung der zeitgleichen optischen Daten konnten physikalische Gr"o"sen des emittierenden Plasma bestimmt werden. Das Resultat wurde mit der sog.\ {\em Blazar-Sequenz} verglichen.

La déficience intellectuelle pose un vrai défi à la pédagogie catéchétique de l’Eglise. Elle questionne l’anthropologie de toute catéchèse, spécialement la perception de la personne en situation de handicap et déplace le centre de gravité de la catéchèse d’un savoir cognitif à une relation personnelle avec l’autre (l’Autre). Les personnes avec une déficience interrogent l’ensemble de la communauté humaine : « Pourquoi Dieu m’a faite ainsi ? » ou encore : « Pourquoi personne ne veut de nous comme amis ? » Ces questions servent de départ pour une recherche à travers l’histoire, la Bible, des textes ecclésiaux et des parcours de catéchèse afin de voir comment y sont perçues les personnes avec une déficience. La difficulté de se faire des amis toutes capacités confondues est conditionnée par notre perception de la déficience. Partant du principe que cette perception est déterminée par nos conceptions religieuses, notamment par notre compréhension d’une soi-disant « perfection adamique », l’auteure cherche une réponse théologiquement et pastoralement ajustée aux deux questions posées. En mettant en résonnance les intuitions des théologies du handicap avec la catéchèse en France, elle dégage des perspectives nouvelles transformant des représentations anthropologiques relatives à la foi chrétienne, permettant une catéchèse « capacitante » qui ouvre des chemins à des amitiés au-delà des barrières de la déficience. / Intellectual disability poses a real challenge to the catechetical pedagogy of the Church. It questions the anthropology of all catechesis, especially the perception of people with a disability and moves the gravitational center of catechesis from cognitive knowledge to a personal relationship with the other (the Other). People with disabilities question the whole human community: "Why did God make me this way?” or "Why does no one want us as friends?” These questions serve as a starting point for a search throughout history, the Bible, ecclesial texts and catechetical tools to see how people with intellectual disabilities are perceived. The difficulty of making friends of all abilities is conditioned by our perception of disability. Assuming that this perception is determined in part by our religious conceptions, including our understanding of a so-called "adamic perfection," the author seeks a theologically and pastorally adjusted response to the two questions posed. By starting the conversation between disability theologies and catechesis in France, she opens up new perspectives, transforming the anthropological representations relating to the Christian faith, allowing a "capacitating" catechesis that opens a pathway to friendships beyond the barriers of disability.

Este trabalho apresenta um estudo sobre o processo de Estampagem Incremental de Chapas, em Latão C-268 de diferentes espessuras (s0: 0.50, 0.70 e 1.00 mm), motivado pela inobservância de pesquisas desta matéria prima neste processo de conformação de chapas. Atualmente, este material tem grande aplicação na confecção de utensílios domésticos (baixelas, travessas, etc) e ferragens para construção civil (espelhos, cubas, etc), instrumentos musicais de sopro e núcleos de radiadores automotivos, tendo assim, um amplo campo de aplicação industrial, e potencial para as aplicações do processo de Estampagem Incremental de Chapas. A pesquisa está pautada na caracterização das matérias primas, para a obtenção de dados como as Curvas de Escoamento, Índices de Anisotropia (r), Curvas Limite de Conformação (CLC) e em experimentos de Estampagem Incremental de Chapas, realizados em uma máquina dedicada a este processo de conformação. Para a realização dos experimentos, foram utilizados Incrementos Verticais com diferentes valores (∆Z: 0.10, 0.50 e 1.00 mm), assim como duas ferramentas de estampagem (DT: Ø10 e Ø15 mm). Foram aplicadas duas formas geométricas diferentes: Tronco de Cone e Tronco de Pirâmide, ambos com perfil radial das paredes verticais. Ao todo, foram realizados 15 experimentos diferentes na modalidade SPIF. Os experimentos foram realizados em uma máquina dedicada ao processo, capaz da aquisição dos valores de Força (FX, FY e FZ) durante a realização dos testes. Com a realização dos experimentos SPIF, foi possível a elaboração da Linha Limite de Fratura – LFC da chapa latão C-268 nas três espessuras investigadas, onde os resultados apontam para valores maiores de deformação verdadeira (1 vs 2), quando comparados aos valores da CLC. Adicionalmente, a LFC das três espessuras de chapas analisadas, apontam os valores das maiores deformações verdadeiras (1) muito próximos, evidenciando neste caso que a diminuição do Incremento Vertical (∆Z) é mais relevante para a estampagem do que o aumento da espessura da chapa. As geometrias Tronco de Cone e Tronco de Pirâmide apresentaram discrepâncias geométricas toleráveis em relação ao perfil projetado, mas diferentes entre si, influenciados pelo retorno elástico diferente de cada geometria. Entretanto, suas fraturas apresentaram o mesmo comportamento, propagação no sentido meridional. Os experimentos SPIF realizados com a ferramenta de estampagem com Ø10mm proporcionaram as maiores profundidades. A medição da espessura final (s1) próximas as regiões fraturadas, comprovou os valores medidos não ultrapassaram os respectivos valores resultantes da expressão matemática Lei do Seno, e ainda, que quanto menor a espessura inicial (s0) da chapa, menor a variação dos valores medidos e calculados. A análise das Forças (FX, FY e FZ) resultantes do processo SPIF mostram que quanto maior o Incremento Vertical (∆Z), maior a espessura inicial (s0) da chapa, e maior do diâmetro (DT) da ferramenta de estampagem, maiores serão as Forças necessárias no SPIF. Adicionalmente, foi possível determinar os valores de Atrito (µ), obtidos em função das Forças (FX, FY e FZ) do processo SPIF. / This paper presents a study of the Incremental Sheet Forming process, in Brass C-268 of different thicknesses (s0: 0.50, 0.70 and 1.00 mm), motivated by non-observance of research of this raw material in this sheet forming process. Currently, this material has great application in the manufacture of household items (plates, platters, etc.) and hardware for building (locks, vats, etc.), wind musical instruments and automotive radiator cores, having thus, a large industrial application field, and potential for the applications of the Incremental Sheet Forming process. The research is based on the characterization of raw materials, to obtain data such as Flow Curves, Anisotropy Indices (r), Forming Limit Curve and in Incremental Sheet Forming experiments, performed on a machine dedicated to this forming process. For the realization of the experiments, Vertical Increments with different values were used (∆Z: 0.10, 0.50 e 1.00 mm), As well as two forming tools (DT: Ø10 e Ø15 mm). Two different geometric forms were applied: Cone Frustum and Pyramid Frustum, both with radial profile of vertical walls. In all, 15 different SPIF experiments were performed. The experiments were carried out in a machine dedicated to the process, able to acquire the values of Force (FX, FY e FZ) during the tests. With the realization of SPIF experiments, it was possible to elaborate the Fracture Forming Line – FFL of Brass C-268 sheet, In the three thicknesses investigated, Where the results indicate higher values of true strain (1 vs 2), when compared to the FLC values. Additionally, the FFL of the three sheet thicknesses analyzed, indicate the values of the highest true deformations (1) very close, evidencing in this case, that the decrease of Vertical Increment (∆Z) is more relevant for the forming than the increase in sheet thickness. The Cone Frustum and Pyramid Frustum geometries presented tolerable geometric discrepancies in relation to the projected profile, more different from each other, influenced by different springback of each geometry. However, their fractures presented the same behavior, meridional direction propagation. The SPIF experiments performed with the forming tool with Ø10mm provided the greatest depths. The final thickness (s1) measurement near the fractured regions, proved the measured values did not exceed the respective values resulting from the mathematical expression Sine Law, and also, that the lower the initial thickness (s0) of sheet, lower the variation of the measured and calculated values. Analysis of Forces (FX, FY e FZ) resulting from the SPIF process, show that the larger the Vertical Increment (∆Z), larger the initial thickness (s0) of the sheet, and larger diameter (DT) of the forming tool, larger will be the necessary forces in SPIF. In addition, it was possible to determine the values of Friction (µ), obtained in function of the SPIF Forces (FX, FY e FZ).

The problem of the forced film condensation heat transfer of pure steam and steam-air mixture flowing downward a tier of horizontal cylinders is investigated numerically and experimentally. Liquid and vapor-air mixture boundary layers were solved by an implicit finite difference scheme. The effects of the free stream non-condensable gas (air) concentration, free stream velocity (Reynolds number), cylinder diameter, temperature difference and angle of inclination on the condensation heat transfer are analyzed. Inline and staggered tubes arrangements are considered. The mathematical model takes into account the effect of staggering of the cylinders and how condensation is affected at the lower cylinders when condensate does not fall on to the center line of the cylinders. An experimental setup was also manufactured and mounted at METU workshop. A set of experiments were conducted to observe the condensation heat transfer phenomenon and to verify the theoretical results. Condensation heat transfer results are available in ranges from (U&amp / #61605 / = 1 - 30 m/s) for free stream velocity, (m1,&amp / #61605 / = 0.01 -0.8) for free stream air mass fraction, (d = 12.7 -50.8 mm) for cylinder diameter and (T&amp / #61605 / -Tw =10-40 K) for temperature difference. Results show that / a remarked reduction in the vapor side heat transfer coefficient is noticed when very small amounts of air mass fractions present in the vapor. In addition, it decreases by increasing in the cylinder diameter and the temperature difference. On the other hand, it increases by increasing the free stream velocity (Reynolds number). Average heat transfer coefficient at the middle and the bottom cylinders increases by increasing the angle of inclination, whereas, no significant change is observed for that of the upper cylinder. Although some discrepancies are noticed, the present study results are inline and in a reasonable agreement with the theory and experiment in the literature. Down the bank, a rapid decrease in the vapor side heat transfer coefficient is noticed. It may be resulted from the combined effects of inundation, decrease in the vapor velocity and increase in the non-condensable gas (air) at the bottom cylinders in the bank. Differences between the present study results and the theoretical and the experimental data may be resulted from the errors in the numerical schemes used. These errors include truncation and round off errors, approximations in the numerical differentiation for interfacial fluxes at the vapor-liquid interface, constant properties assumption and approximations in the initial profiles. Mixing and re-circulation in the steam-air mixture at the lower tubes may be the other reasons for these deviations.

EFFECTS OF OFF-CENTER ANGLE ON THE HEAT TRANSFER COEFFICIENT ON VERTiCAL TIER OF MULTIPLE SPHERICAL SURFACES Kaya, Ebubekir M.S., Department of Mechanical Engineering Supervisor: Assoc. Prof. Dr. Cemil Yamali December 2004, 112 pages The purpose of this study is to investigate the laminar film condensation phenomenon of steam on a vertical tier of multiple spherical surfaces by using both analytical and experimental methods. The analytical heat transfer results were obtained by following the Nusselt type of analysis and represented graphically. In addition, in order to observe the real behavior of the film condensation, an experimental setup was manufactured and experiments were done. In analytical section / mass flow rate, (mean) velocity, film thickness, local heat flux and local heat transfer coefficient values were obtained and plotted as depending on angular position. Moreover, mean heat flux and mean heat transfer coefficient variations were presented with respect to diameter of the sphere and sub-cooling. On the other hand, for the experimental section, heat flux and mean heat transfer coefficient values were obtained and expressed as depending on sub-cooling. To see the effects of off-center angle, setup was inclined for different angles and experiments were repeated for each inclination angle. At the end of the study, mean heat transfer coefficients belong to analytical and experimental studies were compared to each other as well as to the literature.

Este trabalho apresenta um estudo sobre o processo de Estampagem Incremental de Chapas, em Latão C-268 de diferentes espessuras (s0: 0.50, 0.70 e 1.00 mm), motivado pela inobservância de pesquisas desta matéria prima neste processo de conformação de chapas. Atualmente, este material tem grande aplicação na confecção de utensílios domésticos (baixelas, travessas, etc) e ferragens para construção civil (espelhos, cubas, etc), instrumentos musicais de sopro e núcleos de radiadores automotivos, tendo assim, um amplo campo de aplicação industrial, e potencial para as aplicações do processo de Estampagem Incremental de Chapas. A pesquisa está pautada na caracterização das matérias primas, para a obtenção de dados como as Curvas de Escoamento, Índices de Anisotropia (r), Curvas Limite de Conformação (CLC) e em experimentos de Estampagem Incremental de Chapas, realizados em uma máquina dedicada a este processo de conformação. Para a realização dos experimentos, foram utilizados Incrementos Verticais com diferentes valores (∆Z: 0.10, 0.50 e 1.00 mm), assim como duas ferramentas de estampagem (DT: Ø10 e Ø15 mm). Foram aplicadas duas formas geométricas diferentes: Tronco de Cone e Tronco de Pirâmide, ambos com perfil radial das paredes verticais. Ao todo, foram realizados 15 experimentos diferentes na modalidade SPIF. Os experimentos foram realizados em uma máquina dedicada ao processo, capaz da aquisição dos valores de Força (FX, FY e FZ) durante a realização dos testes. Com a realização dos experimentos SPIF, foi possível a elaboração da Linha Limite de Fratura – LFC da chapa latão C-268 nas três espessuras investigadas, onde os resultados apontam para valores maiores de deformação verdadeira (1 vs 2), quando comparados aos valores da CLC. Adicionalmente, a LFC das três espessuras de chapas analisadas, apontam os valores das maiores deformações verdadeiras (1) muito próximos, evidenciando neste caso que a diminuição do Incremento Vertical (∆Z) é mais relevante para a estampagem do que o aumento da espessura da chapa. As geometrias Tronco de Cone e Tronco de Pirâmide apresentaram discrepâncias geométricas toleráveis em relação ao perfil projetado, mas diferentes entre si, influenciados pelo retorno elástico diferente de cada geometria. Entretanto, suas fraturas apresentaram o mesmo comportamento, propagação no sentido meridional. Os experimentos SPIF realizados com a ferramenta de estampagem com Ø10mm proporcionaram as maiores profundidades. A medição da espessura final (s1) próximas as regiões fraturadas, comprovou os valores medidos não ultrapassaram os respectivos valores resultantes da expressão matemática Lei do Seno, e ainda, que quanto menor a espessura inicial (s0) da chapa, menor a variação dos valores medidos e calculados. A análise das Forças (FX, FY e FZ) resultantes do processo SPIF mostram que quanto maior o Incremento Vertical (∆Z), maior a espessura inicial (s0) da chapa, e maior do diâmetro (DT) da ferramenta de estampagem, maiores serão as Forças necessárias no SPIF. Adicionalmente, foi possível determinar os valores de Atrito (µ), obtidos em função das Forças (FX, FY e FZ) do processo SPIF. / This paper presents a study of the Incremental Sheet Forming process, in Brass C-268 of different thicknesses (s0: 0.50, 0.70 and 1.00 mm), motivated by non-observance of research of this raw material in this sheet forming process. Currently, this material has great application in the manufacture of household items (plates, platters, etc.) and hardware for building (locks, vats, etc.), wind musical instruments and automotive radiator cores, having thus, a large industrial application field, and potential for the applications of the Incremental Sheet Forming process. The research is based on the characterization of raw materials, to obtain data such as Flow Curves, Anisotropy Indices (r), Forming Limit Curve and in Incremental Sheet Forming experiments, performed on a machine dedicated to this forming process. For the realization of the experiments, Vertical Increments with different values were used (∆Z: 0.10, 0.50 e 1.00 mm), As well as two forming tools (DT: Ø10 e Ø15 mm). Two different geometric forms were applied: Cone Frustum and Pyramid Frustum, both with radial profile of vertical walls. In all, 15 different SPIF experiments were performed. The experiments were carried out in a machine dedicated to the process, able to acquire the values of Force (FX, FY e FZ) during the tests. With the realization of SPIF experiments, it was possible to elaborate the Fracture Forming Line – FFL of Brass C-268 sheet, In the three thicknesses investigated, Where the results indicate higher values of true strain (1 vs 2), when compared to the FLC values. Additionally, the FFL of the three sheet thicknesses analyzed, indicate the values of the highest true deformations (1) very close, evidencing in this case, that the decrease of Vertical Increment (∆Z) is more relevant for the forming than the increase in sheet thickness. The Cone Frustum and Pyramid Frustum geometries presented tolerable geometric discrepancies in relation to the projected profile, more different from each other, influenced by different springback of each geometry. However, their fractures presented the same behavior, meridional direction propagation. The SPIF experiments performed with the forming tool with Ø10mm provided the greatest depths. The final thickness (s1) measurement near the fractured regions, proved the measured values did not exceed the respective values resulting from the mathematical expression Sine Law, and also, that the lower the initial thickness (s0) of sheet, lower the variation of the measured and calculated values. Analysis of Forces (FX, FY e FZ) resulting from the SPIF process, show that the larger the Vertical Increment (∆Z), larger the initial thickness (s0) of the sheet, and larger diameter (DT) of the forming tool, larger will be the necessary forces in SPIF. In addition, it was possible to determine the values of Friction (µ), obtained in function of the SPIF Forces (FX, FY e FZ).

Este trabalho apresenta um estudo sobre o processo de Estampagem Incremental de Chapas, em Latão C-268 de diferentes espessuras (s0: 0.50, 0.70 e 1.00 mm), motivado pela inobservância de pesquisas desta matéria prima neste processo de conformação de chapas. Atualmente, este material tem grande aplicação na confecção de utensílios domésticos (baixelas, travessas, etc) e ferragens para construção civil (espelhos, cubas, etc), instrumentos musicais de sopro e núcleos de radiadores automotivos, tendo assim, um amplo campo de aplicação industrial, e potencial para as aplicações do processo de Estampagem Incremental de Chapas. A pesquisa está pautada na caracterização das matérias primas, para a obtenção de dados como as Curvas de Escoamento, Índices de Anisotropia (r), Curvas Limite de Conformação (CLC) e em experimentos de Estampagem Incremental de Chapas, realizados em uma máquina dedicada a este processo de conformação. Para a realização dos experimentos, foram utilizados Incrementos Verticais com diferentes valores (∆Z: 0.10, 0.50 e 1.00 mm), assim como duas ferramentas de estampagem (DT: Ø10 e Ø15 mm). Foram aplicadas duas formas geométricas diferentes: Tronco de Cone e Tronco de Pirâmide, ambos com perfil radial das paredes verticais. Ao todo, foram realizados 15 experimentos diferentes na modalidade SPIF. Os experimentos foram realizados em uma máquina dedicada ao processo, capaz da aquisição dos valores de Força (FX, FY e FZ) durante a realização dos testes. Com a realização dos experimentos SPIF, foi possível a elaboração da Linha Limite de Fratura – LFC da chapa latão C-268 nas três espessuras investigadas, onde os resultados apontam para valores maiores de deformação verdadeira (1 vs 2), quando comparados aos valores da CLC. Adicionalmente, a LFC das três espessuras de chapas analisadas, apontam os valores das maiores deformações verdadeiras (1) muito próximos, evidenciando neste caso que a diminuição do Incremento Vertical (∆Z) é mais relevante para a estampagem do que o aumento da espessura da chapa. As geometrias Tronco de Cone e Tronco de Pirâmide apresentaram discrepâncias geométricas toleráveis em relação ao perfil projetado, mas diferentes entre si, influenciados pelo retorno elástico diferente de cada geometria. Entretanto, suas fraturas apresentaram o mesmo comportamento, propagação no sentido meridional. Os experimentos SPIF realizados com a ferramenta de estampagem com Ø10mm proporcionaram as maiores profundidades. A medição da espessura final (s1) próximas as regiões fraturadas, comprovou os valores medidos não ultrapassaram os respectivos valores resultantes da expressão matemática Lei do Seno, e ainda, que quanto menor a espessura inicial (s0) da chapa, menor a variação dos valores medidos e calculados. A análise das Forças (FX, FY e FZ) resultantes do processo SPIF mostram que quanto maior o Incremento Vertical (∆Z), maior a espessura inicial (s0) da chapa, e maior do diâmetro (DT) da ferramenta de estampagem, maiores serão as Forças necessárias no SPIF. Adicionalmente, foi possível determinar os valores de Atrito (µ), obtidos em função das Forças (FX, FY e FZ) do processo SPIF. / This paper presents a study of the Incremental Sheet Forming process, in Brass C-268 of different thicknesses (s0: 0.50, 0.70 and 1.00 mm), motivated by non-observance of research of this raw material in this sheet forming process. Currently, this material has great application in the manufacture of household items (plates, platters, etc.) and hardware for building (locks, vats, etc.), wind musical instruments and automotive radiator cores, having thus, a large industrial application field, and potential for the applications of the Incremental Sheet Forming process. The research is based on the characterization of raw materials, to obtain data such as Flow Curves, Anisotropy Indices (r), Forming Limit Curve and in Incremental Sheet Forming experiments, performed on a machine dedicated to this forming process. For the realization of the experiments, Vertical Increments with different values were used (∆Z: 0.10, 0.50 e 1.00 mm), As well as two forming tools (DT: Ø10 e Ø15 mm). Two different geometric forms were applied: Cone Frustum and Pyramid Frustum, both with radial profile of vertical walls. In all, 15 different SPIF experiments were performed. The experiments were carried out in a machine dedicated to the process, able to acquire the values of Force (FX, FY e FZ) during the tests. With the realization of SPIF experiments, it was possible to elaborate the Fracture Forming Line – FFL of Brass C-268 sheet, In the three thicknesses investigated, Where the results indicate higher values of true strain (1 vs 2), when compared to the FLC values. Additionally, the FFL of the three sheet thicknesses analyzed, indicate the values of the highest true deformations (1) very close, evidencing in this case, that the decrease of Vertical Increment (∆Z) is more relevant for the forming than the increase in sheet thickness. The Cone Frustum and Pyramid Frustum geometries presented tolerable geometric discrepancies in relation to the projected profile, more different from each other, influenced by different springback of each geometry. However, their fractures presented the same behavior, meridional direction propagation. The SPIF experiments performed with the forming tool with Ø10mm provided the greatest depths. The final thickness (s1) measurement near the fractured regions, proved the measured values did not exceed the respective values resulting from the mathematical expression Sine Law, and also, that the lower the initial thickness (s0) of sheet, lower the variation of the measured and calculated values. Analysis of Forces (FX, FY e FZ) resulting from the SPIF process, show that the larger the Vertical Increment (∆Z), larger the initial thickness (s0) of the sheet, and larger diameter (DT) of the forming tool, larger will be the necessary forces in SPIF. In addition, it was possible to determine the values of Friction (µ), obtained in function of the SPIF Forces (FX, FY e FZ).

This study of the reigns of Valerian and Gallienus, two Roman Emperors of the mid-third century after Christ, was undertaken to re-assess their achievements in the light of modern discoveries about the Roman world. The view frequently expressed by historians—that Valerian and, in particular, Gallienus, were to blame for all the misfortunes that occurred in the Empire— has been found incorrect. Gallienus was vigorous and bold in taking action to check the rapid disintegration of the Empire. Although he failed, the reforms that he introduced into the organization of the army and of provincial government lived on after him. His contribution was not so much to discover these changes (largely begun by Septimius Severus) but to carry their development to a definite conclusion. In order to present the history of the period clearly, the study has been divided into two parts, the first dealing with the chronological sequence of events, and the second with administrative policies, or lack of policy, and with social and economic conditions. Many problems still remain unsolved, but the result of this work, it is hoped, has been a version that reasonably accounts for available evidence. / Arts, Faculty of / Classical, Near Eastern and Religious Studies, Department of / Graduate

A combined cycle gas/steam power plant combines a gas turbine (topping cycle) with a steam power plant (bottoming cycle) through the use of a heat recovery steam generator. It uses the hot exhaust of the gas turbine to produce steam which is used to generate additional power in the steam power plant. The aim of this study is to establish the different bottoming cycle performances in terms of the main parameters of heat recovery steam generator and steam cycle for a chosen gas turbine cycle. First of all / for a single steam power cycle, effect of main cycle parameters on cycle performance are analyzed based on first law of thermodynamics. Also, case of existence of a reheater section in a steam cycle is evaluated. For a given gas turbine cycle, three different bottoming cycle configurations are chosen and parametric analysis are carried out based on energy analysis to see the effects of main cycle parameters on cycle performance. These are single pressure cycle, single pressure cycle with supplementary firing and dual pressure cycle. Also, effect of adding a single reheat to single pressure HRSG is evaluated. In single pressure cycle, HRSG generates steam at one pressure level. In dual pressure cycle, HRSG generates steam at two different pressure levels. i.e. high pressure and low pressure. In single pressure cycle with supplementary firing excess oxygen in exhaust gas is fired before entering HRSG by additional fuel input. So, temperature of exhaust gas entering the HRSG rises. Second law analysis is performed to able to see exergy distribution throughout the bottoming plant / furthermore second law efficiency values are obtained for single and dual pressure bottoming cycle configurations as well as basic steam power cycle with and without reheat. It is shown that maximum lost work due to irreversibility is in HRSG for a bottoming cycle in a single pressure gas / steam combined power plant and in boiler for a steam cycle alone. Comparing this with the single pressure cycle shows how the dual pressure cycle makes better use of the exhaust gas in the HRSG that dual pressure combined cycle has highest efficiency values and lost work due to irreversibility in -most significant component- HRSG can be lowered. And also it is shown that by extending the idea of reheat the moisture content is reduced and improvement in the performance is possible for high main steam pressures. Another observation is that supplementary firing increases the steam turbine output compared to the cycle without supplementary firing. The efficiency rises slightly for HP steam pressures higher than 14 MPa at HRSG exit, because the increased steam production also results in increased mass flows removing more energy from the exhaust gas.

Η παρούσα εργασία αφορά στη μελέτη της ανταγωνιστικής αλληλεπίδρασης των Α1/D1 υποδοχέων στο επίπεδο έκφρασης του πρώιμου γονιδίου zif/268 (δείκτης νευρωνικής δραστηριότητας) και της in vivo μεταγωγής σήματος των Α1 και Α2Α υποδοχέων αδενοσίνης κάτω από τη ντοπαμινεργική απονεύρωση στο μυ weaver. Ο μυς weaver αποτελεί ένα γενετικό μοντέλο ντοπαμινεργικής απονεύρωσης, η οποία συμβαίνει σταδιακά, έτσι ώστε το μοντέλο αυτό να προσομοιάζει τη Νόσο Πάρκινσον (ΝΠ) στον άνθρωπο. Στο πρώτο στάδιο της μελέτης προέκυψε το ενδιαφέρον αποτέλεσμα ότι με την ταυτόχρονη ενεργοποίηση των Α1 και D1 υποδοχέων παρατηρήθηκε η αναμενόμενη ανταγωνιστική αλληλεπίδραση (ενδεχομένως μέσω σχηματισμού του ετεροδιμερούς), ενώ με την ενεργοποίηση μόνο των Α1 υποδοχέων στους weaver μύες παρατηρήθηκε αυξημένη ενεργοποίηση των νευρώνων του ραβδωτού σώματος και συγκεκριμένων περιοχών του εγκεφαλικού φλοιού. Η ενεργοποίηση αυτή ήταν μη αναμενόμενη, δεδομένου ότι οι Α1 υποδοχείς (A1Rs) είναι συζευγμένοι με Gi πρωτεΐνες και καταστέλλουν τη μεταγωγή σήματος που οδηγεί στην επαγωγή του zif/268 μέσω του D1R/Gs/cAMP/PKA/pDARPP-32/pCREB μονοπατιού. Η ακόλουθη διερεύνηση του μηχανισμού έδειξε ότι η Α1R-επαγόμενη ενεργοποίηση του zif/268 καταστέλλεται από τον ειδικό ανταγωνιστή των Α2Α υποδοχέων αδενοσίνης (A2ARs) ZM241385 και από τον ειδικό αγωνιστή των D2 υποδοχέων ντοπαμίνης Quinpirole, υποδεικνύοντας την ενεργοποίηση των Α2ΑRs και άρα ενεργοποίηση της έμμεσης οδού. Το αποτέλεσμα αυτό επιβεβαιώθηκε, δεδομένου ότι η διέγερση των Α1Rs προκάλεσε αύξηση της έκφρασης του mRNA της εγκεφαλίνης, αλλά όχι της δυνορφίνης, που αποτελούν δείκτες ενεργοποίησης της έμμεσης και της άμεσης οδού, αντίστοιχα. Το γεγονός ότι ο αγωνιστής των Α1Rs δεν προκαλεί στα φυσιολογικά ζώα ενεργοποίηση του zif/268 mRNA υποδεικνύει την υπερευαίσθητη απόκριση των Α2ARs. Η μελέτη της υπερευαίσθητης αυτής απόκρισης στο μυ weaver έγινε με τη διερεύνηση της μεταγωγής σήματος μετά από in vivo ενεργοποίηση των Α2ΑRs: α) του καθιερωμένου μονοπατιού Α2ΑRs/Gs/AC/cAMP/PKA/pDARPP-32/pCREB, το οποίο οδηγεί στη επαγωγή του zif/268 και β) του μονοπατιού των ΜΑΡΚ. Τα αποτελέσματα έδειξαν αυξημένα βασικά επίπεδα φωσφορυλίωσης της DARPP-32 στη θέση Thr-34. Τα αυξημένα επίπεδα της φωσφορυλιωμένης DARPP-32 πολλαπλασιάζουν τη δράση της ΡΚΑ και άρα διευκολύνουν τη μεταγωγή σήματος μέσω Α2ΑRs/Gs/AC/cAMP/PKA/pDARPP-32/pCREB μονοπατιού. Επομένως, η υπερευαίσθητη απόκριση των Α2ΑRs κάτω από την έλλειψη ντοπαμίνης στο μυ weaver φαίνεται να οφείλεται στα αυξημένα ενδογενή επίπεδα της φωσφορυλιωμένης DARPP-32. Ενδιαφέρον παρουσιάζει το γεγονός ότι τα βασικά επίπεδα φωσφορυλίωσης των πρωτεϊνών ERK1/2(MAPK44/42) είναι αυξημένα στον μυ weaver, αλλά μειώνονται σημαντικά μετά από την ενεργοποίηση των Α2ΑRs. Δεν γνωρίζουμε το μηχανισμό μέσω του οποίου αυξάνονται τα ενδογενή επίπεδα των ERK1/2 και πρέπει να διερευνηθεί περαιτέρω. Το συμπέρασμα όμως που εξάγεται είναι ότι κάτω από τη ντοπαμινεργική απονεύρωση η μεταβίβαση σήματος μέσω των Α2ΑRs δεν ενεργοποιεί την οδό των MAP κινασών. Στην παρούσα in vivo μελέτη αναδεικνύεται ο ρόλος των Α1 και Α2Α υποδοχέων στην λειτουργία των βασικών γαγγλίων κάτω από τη ντοπαμινεργική απονεύρωση. Τα αποτελέσματα αυτά έχουν ιδιαίτερη σημασία δεδομένου ότι εμφανίζονται σε ένα γενετικό μοντέλο παρκινσονισμού, στο οποίο η εκφύλιση των ντοπαμινεργικών νευρώνων είναι σταδιακή και προσομοιάζει τη ΝΠ, και όχι οξεία, όπως σε άλλα τοξικά μοντέλα. Επιπλέον, τα αποτελέσματα αυτά παρουσιάζουν ενδεχομένως κλινικό ενδιαφέρον, δεδομένου ότι η ενεργοποίηση της έμμεσης οδού μέσω Α1Rs από την ενδογενή αδενοσίνη θα επιδείνωνε περαιτέρω τις κινητικές δυσλειτουργίες της ΝΠ. Η πληροφορία αυτή, καθώς και η γνώση για την ενισχυμένη μεταγωγή σήματος μέσω των Α2Α υποδοχέων ενισχύουν την πρόταση για χρήση των Α2Α ανταγωνιστών ως αντιπαρκινσονικά φάρμακα. Δεδομένου ότι σήμερα το ενδιαφέρον είναι στραμμένο στη δημιουργία διμερών προσδεμάτων (bivalent ligands) που μπορούν να δρουν ταυτόχρονα σε δύο υποδοχείς, η συγκεκριμένη πληροφορία θα μπορούσε να χρησιμοποιηθεί για μελλοντική δημιουργία φαρμακευτικού σχήματος που να δρα ταυτόχρονα ως αγωνιστής των D2 υποδοχέων ντοπαμίνης και ως ανταγωνιστής των Α2Α υποδοχέων αδενοσίνης. / The present work studied the antagonistic interaction of A1/D1 receptors at the level of mRNA expression of the immediate early gene zif/268 (used as a marker of neuronal function). In parallel we studied the in vivo signal transduction of A1 and A2A adenosine receptors under dopamine deficiency in weaver mutant. The weaver mutant represents the only genetic animal model of gradual nigrostriatal neuron degeneration, which can be characterized as a pathophysiological phenocopy of Parkinson’s Disease. In the first part of the study, the co-activation of A1 and D1 receptors revealed the well-known antagonistic interaction of these receptors (possibly through the formation of A1/D1 heterodimer) in weaver mutant. An interesting result was that the activation of A1 receptors alone did induce zif/268 mRNA expression in stiatal and specific cortical neurons in weaver mutant. This induction was not expected, since A1 receptors are Gi-coupled and suppress the signal transduction pathway that leads to zif/268 induction through AC/PKA/p-DARPP-32/pCREB cascade. Further study, revealed that the A1 receptor-induced zif/268 mRNA expression is counteracted by the A2A receptor selective antagonist ZM241385 and by the D2 receptor selective agonist Quinpirole, suggesting the activation of A2A receptors and thus the activation of the “indirect pathway”. Moreover, A1 receptors activation induced the expression of enkephalin mRNA, but not of dynorphin, which are considered as marker of neuronal activation of the “indirect” and the “direct” pathway, respectively. The fact that the A1 receptor agonist did not induced zif/268 mRNA expression in +/+ animals indicates that under dopamine deficiency the A2A receptors react with a supersensitive response. This response was analyzed in weaver mouse after in vivo A2A receptor activation: a) by examining the classical signal transduction pathway of A2A receptors/AC/PKA/p-DARPP-32/pCREB, which leads to zif/268 expression and b) by studying the MAPK cascade. Results showed increased basal phosphorylation levels of DARPP-32 (dopamine- and cAMP-regulated phosphoprotein, MW 32kDa) of Thr-34 in weaver compared to control mice. Increased phosphoThr34-DARPP-32 would amplify the effects of the PKA and thus facilitating the signal transduction through A2A receptors/AC/PKA/p-DARPP-32/pCREB. Therefore, the A2A receptors supersensitive response under dopamine deficiency in weaver mutant seems to be due to elevated endogenous phosphorylation levels of DARPP-32. Interestingly, while the basal phosphorylation levels of ERK1/2 (MAPK44/42) are elevated in weaver mutant, they are significantly reduced after A2A receptor activation. Although we do not know the mechanism through which the endogenous ERK1/2 levels are elevated, the conclusion is that, under dopamine deficiency, A2A receptors do not activate MAPK cascade. The present in vivo study demonstrates the role of A1 and A2A adenosine receptors in the function of basal ganglia under dopamine deficiency. Our results are significant since the expreriments were performed in a genetic parkinsonian model, in which the dopaminergic neurons are gradually degenerated and thus simulate the human PD, and not in an acute toxic model. Moreover, these results could be of possible clinical relevance, since the activation of A1 receptors by endogenous adenosine would exaggerate the motor dysfunctions of PD. Furthermore, the enhanced signal transduction pathway through A2A receptors supports the suggestion that the A2A receptor antagonists as antiparkinsonian agents. Given the well-known A2A/D2 antagonistic interaction, new therapeutical prospectives would involve the development of pharmacological bivalent ligands, which can interact with the A2A/D2 receptors and act simultaneously as A2A receptor antagonists and as D2 receptor agonists.