Yes / Purpose: Two binocular sources of information serve motion-in-depth (MID) perception: changes in disparity over time (CD), and interocular velocity differences (IOVD). While CD requires the computation of small spatial disparities, IOVD could be computed from a much lower-resolution signal. IOVD signals therefore might still be available under conditions of binocular vision impairment (BVI) with limited or no stereopsis, e.g. amblyopia. Methods: Sensitivity to CD and IOVD was measured in adults who had undergone therapy to correct optical misalignment or amblyopia in childhood (n=16), as well as normal vision controls with good stereoacuity (n=8). Observers discriminated the interval containing a smoothly-oscillating MID “test” stimulus from a “control” stimulus in a two-interval forced choice (2IFC) paradigm. Results: Of the BVI observers with no static stereoacuity (n=9), one displayed evidence for sensitivity to IOVD only, while there was otherwise no sensitivity for either CD or IOVD in the group. Generally, BVI observers with measurable stereoacuity (n=7) displayed a pattern resembling the control group: showing a similar sensitivity for both cues. A neutral-density (ND) filter placed in front of the fixing eye in a subset of BVI observers did not improve performance. Conclusions: In one BVI observer there was preserved sensitivity to IOVD but not CD, though overall only those BVI observers with at least gross stereopsis were able to detect disparity-based or velocity-based cues to MID. The results imply that these logically distinct information sources are somehow coupled, and in some cases BVI observers with no stereopsis may still retain sensitivity to IOVD. / UK Biotechnology and Biological 498 Sciences Research Council (BBSRC): BB/M002543/1 (Alex R. Wade) BB/M001660/1 (Julie 499 M. Harris) and BB/M001210/1 (Marina Bloj)

The name of the work: Shape changes in the axial system during respiration Goal of the work: the main objective is to perform a case study of brass parameters and changes the shape of the trunk during the ventilation maneuver, prepare the correct methodology of research and to conduct separate measurements. The thesis will be divided into two parts, the first will contain the theoretical background to the subject, in the second part will then be described by the research, where I measured the change in the volume of the lungs in relation to time, assess the impact of implemented ventilation maneuver on the individual probands and examine the respiratory dynamics in selected ventilation maneuver. Methods: in the framework of the fulfilment of the tasks of this work have been carried out experiments with the use of 3D kinematic record with Qualisys and spirometric measurement. The experiment involved three probands aged 20 to 40 specific common features. Each of the proband performed during the measurement of quiet breathing, maximum inhalation and exhalation and ventilation maneuver. Measurements were carried out in one day under standard conditions, measurements made on the day of probands quiet breathing, maximum inhalation and exhalation and ventilation maneuver (5 min total). Data records were...

Les centrales inertielles (triade de capteurs inertiels dont la fusion des données permet l’estimation de l’orientation d’un corps rigide) sont de plus en plus populaires en biomécanique. Toutefois, les qualités métrologiques des centrales inertielles (CI) sont peu documentées et leur capacité à identifier des incapacités liées à la mobilité, sous-évaluée. Objectifs : (i) Caractériser la validité de la mesure d’orientation issue de CI ; (ii) Optimiser la justesse et la fidélité de ces mesures; et (iii) Proposer des métriques de mobilité basées sur les mesures d’orientation issues de CI. Méthodologie et résultats : La validité de la mesure d’orientation de différents types de CI a d’abord été évaluée en conditions contrôlées, à l’aide d’une table motorisée et d’une mesure étalon. Il a ainsi été démontré que les mesures d’orientation issues de CI ont une justesse acceptable lors de mouvements lents (justesse moyenne ≤ 3.1º), mais que cette justesse se dégrade avec l’augmentation de la vitesse de rotation. Afin d’évaluer l’impact de ces constatations en contexte clinique d’évaluation de la mobilité, 20 participants ont porté un vêtement incorporant 17 CI lors de la réalisation de diverses tâches de mobilité (transferts assis-debout, marche, retournements). La comparaison des mesures des CI avec celles d’un système étalon a permis de dresser un portrait descriptif des variations de justesse selon la tâche exécutée et le segment/l’articulation mesuré. À partir de ces constats, l’optimisation de la mesure d’orientation issue de CI est abordée d’un point de vue utilisateur, démontrant le potentiel d’un réseau de neurones artificiel comme outil de rétroaction autonome de la qualité de la mesure d’orientation (sensibilité et spécificité ≥ 83%). Afin d’améliorer la robustesse des mesures de cinématique articulaire aux variations environnementales, l’ajout d’une photo et d’un algorithme d’estimation de pose tridimensionnelle est proposé. Lors d’essais de marche (n=60), la justesse moyenne de l’orientation à la cheville a ainsi été améliorée de 6.7° à 2.8º. Finalement, la caractérisation de la signature de la cinématique tête-tronc pendant une tâche de retournement (variables : angle maximal tête-tronc, amplitude des commandes neuromusculaires) a démontré un bon pouvoir discriminant auprès de participants âgés sains (n=15) et de patients atteints de Parkinson (PD, n=15). Ces métriques ont également démontré une bonne sensibilité au changement, permettant l’identification des différents états de médication des participants PD. Conclusion : Les mesures d’orientation issues de CI ont leur place pour l’évaluation de la mobilité. Toutefois, la portée clinique réelle de ce type de système ne sera atteinte que lorsqu’il sera intégré et validé à même un outil de mesure clinique. / Abstract : Inertial measurement of motion is emerging as an alternative to 3D motion capture systems in biomechanics. Inertial measurement units (IMUs) are composed of accelerometers, gyroscopes and magnetometers which data are fed into a fusion algorithm to determine the orientation of a rigid body in a global reference frame. Although IMUs offer advantages over traditional methods of motion capture, the value of their orientation measurement for biomechanics is not well documented. Objectives: (i) To characterize the validity of the orientation measurement issued from IMUs; (ii) To optimize the validity and the reliability of these measurements; and (iii) To propose mobility metrics based on the orientation measurement obtained from IMUs. Methods and results: The criterion of validity of multiple types of IMUs was characterized using a controlled bench test and a gold standard. Accuracy of orientation measurement was shown to be acceptable under slow conditions of motion (mean accuracy ≤ 3.1º), but it was also demonstrated that an increase in velocity worsens accuracy. The impact of those findings on clinical mobility evaluation was then assessed in the lab, with 20 participants wearing an inertial suit while performing typical mobility tasks (standing-up, walking, turning). Comparison of the assessed IMUs orientation measurements with those from an optical gold standard allowed to capture a portrait of the variation in accuracy across tasks, segments and joints. The optimization process was then approached from a user perspective, first demonstrating the capability of an artificial neural network to autonomously assess the quality of orientation data sequences (sensitivity and specificity ≥ 83%). The issue of joint orientation accuracy in magnetically perturbed environment was also specifically addressed, demonstrating the ability of a 2D photograph coupled with a 3D pose estimation algorithm to improve mean ankle orientation accuracy from 6.7° to 2.8º when walking (n=60 trials). Finally, characterization of the turn cranio-caudal kinematics signature (variables: maximum head to trunk angle and neuromuscular commands amplitude) has demonstrated a good ability to discriminate between healthy older adults (n=15) and early stages of Parkinson’s disease patients (PD, n=15). Metrics have also shown a good sensitivity to change, enabling to detect changes in PD medication states. Conclusion: IMUs offer a complementary solution for mobility assessment in clinical biomechanics. However, the full potential of this technology will only be reached when IMUs will be integrated and validated within a clinical tool.

Cette thèse s’inscrit dans un projet à long terme de conception de nouvelle prothèse de l’Articulation Temporo-Mandibulaire (ATM). Afin de faciliter une caractérisation non invasive de l’ATM, elle a conduit à l’élaboration d’un modèle élément finis plan de l’ATM. Le modèle, construit à partir de relevés IRM, intègre le ménisque ainsi que les insertions musculaires et ligamentaires. Il est commandé en déplacements imposés tout d’abord et en efforts imposés ensuite. Les déplacements ont été mesurés par analyse vidéo 3D et les efforts musculaires ont été évalués par EMG au cours de travaux antérieurs réalisés au sein du laboratoire. Le modèle est ici exploité pour simuler un mouvement d’ouverture et un serrage inter-incisives dans trois configurations qui correspondent à des ouvertures de 5 mm, 25 mm et 30 mm. Les résultats de ces simulations, validés par IRM, ont permis de caractériser le rôle du disque articulaire de l’ATM dans la réalisation des déplacements et la transmission des efforts. L’étude souligne la nécessité de rechercher des solutions technologiques de remplacement du disque articulaire lors de la conception d’une nouvelle prothèse. / This study presents a part of a long-term project that aims to design a new prosthesis for the Temporomandibular Joint (TMJ). In order to facilitate a non-invasive characterization of the TMJ, a plane finite element model of the joint has been elaborated starting from MRI images. The model integrates the meniscus as well as the principal ligaments and the main muscular insertions. It has been driven firstly with displacements and then with forces. The displacements have been measured using a 3D motion analysis system and the muscles forces have been taken from anterior former EMG studies led in the laboratory. An opening movement and inter-incisors clenching in three configurations which correspond to openings of 5, 25 and 30 mm have been simulated. The results of these simulations, validated by MRI, made it possible to characterize the function of the articular disk during the movement and the transmission of actions. This study underlines the necessity of seeking technological solutions to replace the meniscus when designing a new prosthesis.

The aim of this dissertation was to evaluate and statistically compare the data of the distance of movement and player load (PL) with respect to the player specializations and with respect to the result of rallies. The analysis used the method of 3D kinematic motion analysis of a video recording of the official play-off match in the elite women's category. 3D reconstruction accuracy was calculated with a standard deviation of 0.0296 m (0.3%). A total of 14 players were evaluated (age = 25 ± 6 years; height = 182.3 ± 6.2 cm; weight = 72.1 ± 5.8 kg) in a total of 4 sets. 85% of all rallies lasted up to 12.4 s and 95% lasted up to 18 s. The average duration of the rally reached 7.76 ± 5.1 s. In the range of 0.7 m to 2 m was performed 91.8 ± 1.3 % of distance of movement over 0.7 m. In the range of 0 m to 0.7 m, the specialization spiker reached 60.5% of the total distance of movement. For blocker it was 59.8%, setter reached 54.1%, Opposite reached 62.1% and libero 57.9%. The highest ratio of movement was reached by the spiker for the forward direction (35.8%). The highest distance of movement was reached by the setter (1648 m). Players reached at 50 % speed value from 1.32 m/s in the backward direction for the blocker and setter, up to the maximum speed at 50 % for the setter with a value of 2.09 m/s...

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