Global ETD Search

11	Variations in alkaloidal constituents of plant tissue cultures Essa, A. K. January 1987 (has links) No description available. 572 Alkaloid metabolites of plants
12	Synthetic approaches to the alkaloid himbacine Bennett, P. A. R. January 1988 (has links) No description available. 547 Alkaloid himbacine synthesis
13	Tropane alkaloid production in immobilized plant cell cultures Collinge, Margaret Ann January 1987 (has links) No description available. 572 Biosynthesis of plant alkaloid
14	Synthetic studies toward palau ne and enantioselective total synthesis of biogenetically related (+)-phakellin and (+)-monobromophakellin Wang, Shaohui 15 May 2009 (has links) Oroidin alkaloids, also known as pyrrole-imidazole alkaloids, have become a hot area of chemical and biological research due to their diverse and intriguing structural features and biological activities. Palau'amine (i), one of the hexacyclic oroidin-derived secondary metabolites, contains a fully substituted chloro-cyclopentane ring, a piperazinone moiety and two cyclic guanidines. With the uniqueness and complexity of its structure, palau’amine has been a synthetic challenge and has not yet succumbed to total synthesis. The overall objective of this work was to explore synthetic pathways toward palau’amine and biogenetically related congeners. Most of the work was focused on developing a synthetic pathway for the palau’amine structure proposed in its isolation report dated back to 1993. Starting from a Diels-Alder adduct (iii), oxidation/chlorination followed by phakellin (ii) annulation afforded an advanced pentacyclic intermediate possessing all the carbon framework and all but one ring system of palau’amine. Recently, however, a series of reports questioned the originally proposed palau’amine structure and called for a revision of the stereochemistry of two carbon centers (iv). Now palau’amine has an identical chlorocyclopentane core with axinellamine (vi). With the target changed, we devised a new biomimetic pathway toward both natural products via a common intermediate (v), which was synthesized in 12 steps from the Diels-Alder adduct (iii). alkaloid palau'amine phakellin synthesis
15	Synthetic studies toward palau ne and enantioselective total synthesis of biogenetically related (+)-phakellin and (+)-monobromophakellin Wang, Shaohui 15 May 2009 (has links) Oroidin alkaloids, also known as pyrrole-imidazole alkaloids, have become a hot area of chemical and biological research due to their diverse and intriguing structural features and biological activities. Palau'amine (i), one of the hexacyclic oroidin-derived secondary metabolites, contains a fully substituted chloro-cyclopentane ring, a piperazinone moiety and two cyclic guanidines. With the uniqueness and complexity of its structure, palau’amine has been a synthetic challenge and has not yet succumbed to total synthesis. The overall objective of this work was to explore synthetic pathways toward palau’amine and biogenetically related congeners. Most of the work was focused on developing a synthetic pathway for the palau’amine structure proposed in its isolation report dated back to 1993. Starting from a Diels-Alder adduct (iii), oxidation/chlorination followed by phakellin (ii) annulation afforded an advanced pentacyclic intermediate possessing all the carbon framework and all but one ring system of palau’amine. Recently, however, a series of reports questioned the originally proposed palau’amine structure and called for a revision of the stereochemistry of two carbon centers (iv). Now palau’amine has an identical chlorocyclopentane core with axinellamine (vi). With the target changed, we devised a new biomimetic pathway toward both natural products via a common intermediate (v), which was synthesized in 12 steps from the Diels-Alder adduct (iii). alkaloid palau'amine phakellin synthesis
16	Synthetic Studies of Phenanthridines Lin, Chao-hung 03 August 2005 (has links) none Alkaloid Coupling Reaction
17	Synthetic Studies of Pyrrolophenanthridines Chen, Xie-ying 12 June 2006 (has links) The pyrrolophenanthridine class of alkaloids which have been isolated from various species of Amaryllidaceae.In intramolecular radicalcyclization, we used three methods to synthesize pyrrolophenanthridine. Pyrrolophenanthridine PIFA Radical Alkaloid
18	Chemistry of diazonium tetraflouroborates : Studies on the enantioselective synthesis of lycorine Rycroft, A. D. January 1988 (has links) No description available. 547 Lycorine alkaloid synthesis
19	Studies in the synthesis of piperidine alkaloids Mosts, R. C. January 1987 (has links) No description available. 547 Piperidine alkaloid synthesis
20	Synthesis of pipecolic acid derivatives via aza-Diels-Alder reactions Smith, Peter Duncan January 2000 (has links) No description available. 547 Piperidine alkaloid synthesis

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