Global ETD Search

131	Septic Arthritis Associated With Chickenpox Feierabend, R H. 01 November 1991 (has links) No description available. adolescent therapeutic use) arthritis infectious (diagnosis drug therapy etiology) arthroscopy chickenpox (complications) child preschool drainage female humans infant knee male streptococcal infections (diagnosis drug therapy etiology) streptococcus pyogenes Family Medicine
132	Diluted antibiotics for treating traumatized immature teeth Sabrah, Ala'a Hussein Aref, 1984- January 2014 (has links) Indiana University-Purdue University Indianapolis (IUPUI) / Endodontic regeneration (ERP) has been successfully used in the treatment of traumatized immature teeth. The procedure has three essential steps: disinfecting the root canal (i.e. triple antibiotic paste (TAP) or double antibiotic paste (DAP)), provoking bleeding inside the canal to form a scaffold upon which pulp stem cells will be deposited and continue root growth, and creating a good coronal seal. Previous research has reported that antibiotic pastes (TAP and DAP) are cytotoxic to stem cells in the concentrations commonly used in endodontic regeneration (1000 mg/mL). To decrease the adverse effects on stem cells and increase the rate of success of the regeneration, defining appropriate antibiotic concentrations for ERP is critical. In this project, five in-vitro experiments were conducted to determine the breakpoint dilutions of both TAP and DAP medicaments, and to prepare a suitable novel pastes containing diluted TAP or DAP medicaments for ERP. In the first experiment, we compared the antibacterial effect of TAP, and DAP against early biofilm formation of Enterococcus faecalis (E. faecalis) and Porphyromonas gingivalis bacteria. In the second study, we investigated the antibacterial effect of various dilutions of TAP and DAP antibiotic medicaments against established E. faecalis biofilm. In the third experiment, we investigated longitudinally the residual antibacterial activity of human radicular dentin treated with 1000, 1 or 0.5 mg/ml of TAP and DAP. In the fourth study, we investigated the cytotoxic effect of various dilutions of TAP and DAP antibiotic medicaments on the survival of human dental pulp stem cells (DPSC). And in the fifth experiment, we investigated the antibacterial and cytotoxic effect of novel intracanal medicaments consisting of methylcellulose (MC) and/or propylene glycol (PG) mixed with 1mg/ml of TAP or DAP. 1 mg/ml of DAP or TAP medicaments had a significant antibacterial effect against early bacterial biofilm formation, and established bacterial biofilm. Furthermore, 1 mg/ml had a residual antibacterial activity comparable to 1000 mg/ml. The novel intracanal medicaments had comparable antibacterial effect to currently used medicaments (1000 mg/ml). Additionally, the novel intracanal medicaments significantly enhanced DPSC metabolic activity, compared to currently used medicaments in endodontic regeneration procedures. Traumatized teeth Immature teeth Triple antibiotic paste Double antibiotic paste Endodontic regeneration Tooth Injuries -- therapy Guided Tissue Regeneration -- methods Regeneration -- drug effects Stem Cells -- drug effects Dentin -- drug effects Biofilms -- drug effects Dental Pulp -- cytology
133	Chlamydia Trachomatis Persistence in Vitro: An Overview Wyrick, Priscilla B. 15 June 2010 (has links) Chlamydiae growing in target mucosal human epithelial cells in vitro can transition from their normal developmental cycle progression, alternating between infectious but metabolically inactive elementary bodies to metabolically active but noninfectious reticulate bodies (RBs) and back to elementary bodies, into a state of persistence. Persistence in vitro is defined as viable but noncultivable chlamydiae involving morphologically enlarged, aberrant, and nondividing RBs. The condition is reversible, yielding infectious elementary bodies after removal of the inducers, including penicillin, interferon-gamma, iron or nutrient starvation, concomitant herpes infection, or maturation of the host cell into its physiologically differentiated state. All aberrant RB phenotypes are not the same, owing to differing up- or down-regulated chlamydial gene sets and subsequent host responses. Although all persistence-inducing conditions exist in vivo, key questions include (1) whether or not aberrant chlamydial RBs occur in vivo during the alternating acute-silent chronic-acute chlamydial infection scenario that exists in infected patients and animals and (2) whether such aberrant RBs can contribute to prolonged, chronic inflammation, fibrosis, and scarring. delivery of health care anti-bacterial agents (pharmacology) chlamydia infections (microbiology) chlamydia trachomatis (cytology drug effects growth & development pathogenicity physiology) endometrium (microbiology) epithelial cells (microbiology) female humans phenotypenvironment environmental health health services accessibility health status humans hygiene life style public health sanitation United States Biomedical Sciences
134	Respiratory Infections in Ambulatory Adults. Choosing the Best Treatment Perlman, P E., Ginn, D R. 01 January 1990 (has links) The diagnosis and treatment of respiratory tract infections in ambulatory adults is challenging. The prevalence of these conditions outstrips the medical profession's efficiency and effectiveness in dealing with them. However, selecting diagnostic techniques that identify causative organisms and therapeutic agents targeted to those organisms should lead to a reduction in the morbidity and mortality associated with these illnesses. adult aged ambulatory care anti-bacterial agents (therapeutic use) bronchitis (diagnosis drug therapy etiology) child common cold (diagnosis etiology prevention & control therapy) diagnosis differential epiglottitis (diagnosis) humans influenza human (diagnosis etiology prevention & control therapy) middle aged otitis media (diagnosis drug therapy) pharyngitis (diagnosis drug therapy etiology) pneumonia (diagnosis therapy) respiratory tract infections (diagnosis etiology therapy) sinusitis (diagnosis drug therapy etiology) virus diseases (complications) QCOM

Page generated in 0.152 seconds