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Towards a practical ecclesiology for urban ScotlandJohnstone, Harry Martin January 2005 (has links)
This research is praxiological in nature, arising out of committed action and leading to more informed urban ecclesiological practice in Scotland. It acknowledges the current haemorrhaging of membership and influence facing the Church of Scotland - felt most acutely in the poorest parts of the country - and seeks to plot a practical urban ecclesiology which takes seriously both the urban context and also the gospel priority towards the poorest and most marginalised. Chapter One provides an autobiographical backcloth to the research and highlights the three core principles underlying it: a preferential option for the poor; an understanding of knowledge as situated; and a commitment to an abductive research process. Chapter Two outlines the research methodology and, in particular, justifies the use of Case Studies, with Focus Groups and semi-structured Interviews, as an appropriate research model. Chapter Three focuses on the nature of the post-industrial city. It highlights globalisation, environmentalism and the collapse of western-style democracy as three of the key issues in the current urban context. It considers post-war urban regeneration, highlighting the failings of a model substantially dominated by buildings and a top-down strategy. Chapter Four is concerned with the nature of poverty in Scotland today, including how such poverty can be defined and measured. The causes of poverty are understood structurally and a particular critique of New Labour's social inclusion policies is offered, based on an analysis of their underlying political philosophy of communitarianism and the Third Way. Chapter Five draws on the different theological and ecclesiological responses to the urban and to poverty and, in particular, upon Latin American Liberation Theology and Urban Theology in Britain since 1985. Through an exploration of Pentecostalism, it highlights the need to develop appropriate ecclesiological models which take the nature of rooted hybrid spirituality more seriously. In Chapter Six the focus of the research narrows down to look at Glasgow, giving consideration to both the effectiveness of the city's place-marketing strategy and also some of the patterns of church life in the city. Chapter Seven focuses upon four Case Studies. These affirm and inform the conclusions reached in previous chapters, highlighting the failure of urban policy to adequately address poverty and the need of the Church to move beyond a 'project-based' response. The research also highlights the importance of church buildings as places of sanctuary and of the 'cultural sectarianism' which continues to pervade the culture of west central Scotland. Chapter Eight represents an attempt to return to informed practice, highlighting how some of the key concepts and findings within the research are informing the developing strategy and practice of the Church of Scotland's Priority Areas Committee.
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The relationship between Christian daughters-in-law and their non-Christian mothers-in-law in Taiwan : a theological and pastoral challengeHung, Yung-Ju January 2016 (has links)
What are the relational dynamics between Taiwanese Christian daughters-in-law (D-Ls) and their non-Christian mothers-in-law (M-Ls)? How does Christian faith influence their intergenerational relations? How best can a caregiver offer appropriate pastoral support and assist Christian women in dealing with their non-Christian M-Ls? These issues and problems have been largely ignored in the relative literature and have arisen from of my pastoral work and personal experience. As a female pastor and D-L, set out this study seeking to integrate professional and academic knowledge in order to answer these questions. This study focuses on women’s experiences, attempting to reveal those relationship issues, and determine any problems underscoring the daily interactions of D-L—M-L in Taiwanese society. In order to meet these aims, the thesis engages with feminist pastoral theology, social science methodology, psychological analysis, and cultural studies. The first part of this study explores literature relevant to the topic, and the living context of Taiwanese D-Ls, as well as feminist pastoral theology. It is concerned with how traditional Chinese and Western cultures define roles and construct intergenerational relationships. Social transition, tension between tradition and modernity, and the struggles and challenges in relation to these intergenerational relationships are examined. The traditional male-centred theological paradigms, in which gender is interpreted and which must be reinterpreted and reconstructed for developing feminist theology, is also discussed. The second part of this study describes its feminist research methodology. It sets out a framework for collecting data to aid in developing an understanding of Taiwanese Christian women’s experience. Focus group discussions were used to explore the collective voice of the D-Ls. The last part of this study involves the presentation of research findings, discussions, and suggestions for further thought and action. It illustrates key findings from analysis of the focus group discussions, and describes the daily interaction and cultural ideology they present, along with the roles husbands, fathers-in-law (F-L), children, and other family members play in the web of relationships. The findings reveal that D-Ls face the challenges of an androcentric and hierarchical family culture, a close-knit family web, and unequal power relations. Different religious practices impact upon the D-L-M-L relationship and this can be a source of tension or conflict. Christian teachings also convey potentially androcentric messages for women that can affect their self-image and cause other harmful consequences. However, many participating women indicated that Christian beliefs provide them with a spiritual strength which has transformed their lives, and led to relational restoration. The Bible, teachings and church groups provide religious resources that support them in the face of relational challenges. I end with self-reflection, noting the need for further theological construction, and propose an alternative model of Triune love, based upon feminist interpretation, as a foundation for family renewal and women’s emancipation. This theological model has implications for new forms of pastoral care which can promote gender equality and non-hierarchical, intergenerational relationships.
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Mission-shaped curacy? : reshaping curacy for effective formation for authentic ministry in the twenty-first century Church of EnglandLongden, Lee Paul January 2012 (has links)
This thesis poses the research question of whether curacy in the Church of England, in its current majority model of one curate in one benefice under the supervision of one training incumbent, continues to offer the most productive space for the post-ordination ongoing formation of the newly ordained. It uses an interdisciplinary methodology, in which theology and ecclesiology are brought into dialogue with the sociological thought of Casanova and Bourdieu, with Stanislavski’s theory of method acting, and with performance practice in art music and popular music. It additionally asks questions of how the increasingly complex external and internal contexts for ministry might be productively conceptualized, and of what kinds of ordained ministers might be needed by the twenty-first century Church of England. Consideration of these questions contributes to the conclusion that whilst aspects of good practice can usefully be retained from the current model of curacy, contextual demands and the changing nature of the role of the ordained, coupled with a significant shift in the demographic profile of those coming forward for ordination, call for a reframing of its structures.
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Syncretic beliefs and practices amongst Muslims in Lagos state Nigeria : with special reference to the Yoruba speaking people of EpeBalogun, Muhsin Adekunle January 2011 (has links)
Different disciplines have explored the history of Islām in Yoruba land which started in the early 18th century. However, the impact of religious syncretism has not been systematically studied. Therefore, this thesis examines the extent of the involvement of Yoruba Muslims in syncretic beliefs and practices in Nigeria using the Lagos State as a case study, with a view to bringing out the impact of Tawḥīd on them. In agreement with previous research, this study notes that there is a prevalence of religious syncretism among many Yoruba Muslims, but it principally argues that its impact affects many of them negatively. If continuous awareness campaign could be carried out, the phenomenon will be reduced. A triangulated method was used to carry out this study. The findings of this thesis indicated reappraisal of the problem associated with many Yoruba Muslims’ persistence in syncretism and its implications on their faith (īman). While this study appreciates the attempts of some scholars to eradicate this endemic problem, it reveals that Tawḥīd is not yet inculcated into many Yoruba Muslims within the Yoruba religio-cultural context. Therefore, a concerted effort is necessary among all stakeholders in the task of promoting the effective instillation of practical Tawḥīd.
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Décomposition et détection de structures géométriques en imagerieGilles, Jérôme 22 June 2006 (has links) (PDF)
Dans cette thèse, nous nous intéressons aux méthodes permettant de décomposer une image en deux parties: l'une contenant les structures (ou objets) de l'image et l'autre les textures. Le point de départ de ces travaux est le modèle proposé par Yves Meyer en 1999 puis les travaux de Jean-François Aujol pour les aspects algorithmiques.<br />Après une étude théorique de ces approches, nous proposons une extension au cas des images bruitées nous permettant d'obtenir alors une décomposition en trois composantes: structures + textures + bruit.<br />Par ailleurs, nous proposons une méthode spécifique en vue d'évaluer les résultats obtenus à partir des différents alggorithmes. <br />Enfin, nous présentons quelques applications des ces méthodes de décomposition d'image, notamment un algorithme de détection de réseaux routiers en imagerie aérienne ou satellitaire. Cet algorithme combine décomposition d'image, détection d'alignements par la théorie de la Gestalt et modèle déformable.
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Παρατηρησιακή μελέτη και μοντελοποίηση διπλών εκλειπτικών συστημάτων αστέρων W UMa / Observational study and modeling of close eclipsing binary stars of W UMa typeΠαπαγεωργίου, Αθανάσιος 27 April 2015 (has links)
Η μελέτη των διπλών εκλειπτικών συστημάτων παραμένει ένα από τα πιο ενδιαφέροντα ερευνητικά πεδία της αστροφυσικής γιατί παρέχει την πιο ακριβή μέθοδο υπολογισμού των βασικών αστρικών μεγεθών (μαζών, ακτίνων, θερμοκρασιών) αλλά και κάθε μορφής αστρικής δραστηριότητας που αναπτύσσεται (κηλίδες, δίσκοι προαύξησης ύλης, αναπάλσεις) μέσα από τη μακρόχρονη μεταβολή της περιόδου τους. Επιπλέον επιτρέπει τον έλεγχο των θεωριών αστρικής εξέλιξης μέσα από την αλληλεπίδρασή τους αλλά και την πρόβλεψη παρουσίας τρίτων σωμάτων αστρικής ή μη φύσης. Σε αυτήν τη διατριβή μελετάται μία ιδιαίτερη κατηγορία διπλών εκλειπτικών συστημάτων σε επαφή, τα W UMa τα οποία αποτελούνται από αστέρες κύριας ακολουθίας οι οποίοι βρίσκονται σε υπερεπαφή, και χαρακτηρίζονται από τις μικρότερες περιόδους κι άρα από τη μικρότερη στροφορμή. Σκοπός της είναι τόσο η παρατηρησιακή μελέτη και ανάλυση συστημάτων W UMa που παρουσιάζουν ιδιαίτερο ενδιαφέρον όσο και η ανάγκη ανάπτυξης μεθοδολογίας μοντελοποίησης για την εξαγωγή της μέγιστης πληροφορίας και ελέγχου των εξαγόμενων φυσικών παραμέτρων κάτω από την εφαρμογή σύγχρονων στατιστικών μεθόδων. Το πρώτο μέρος της επικεντρώνεται στη σκιαγράφηση του θεωρητικού επιστημονικού πλαισίου περιγραφής των διπλών εκλειπτικών αστρικών συστημάτων σε επαφή. Το Κεφάλαιο1 αναφέρεται στη γεωμετρία των τροχιών και στη φυσική των αστέρων του συστήματος, στην περιγραφή του μοντέλου Roche και στην αλληλεπίδραση των μελών καθώς και στη δυναμική των συστημάτων όπως αυτή εκδηλώνεται από την παρατηρούμενη μεταβολή της περιόδου του. Το Κεφάλαιο 2 αναφέρεται στις φωτομετρικές παρατηρήσεις που έγιναν κατά την διάρκεια της παρούσας διατριβής καθώς και στις αυτοματοποιημένες μεθόδους επεξεργασίας και ανάλυσης των παρατηρησιακών αστρονομικών δεδομένων οι οποίες αναπτύχθηκαν. Το Κεφάλαιο 3 περιγράφει τις σύγχρονες τεχνικές μοντελοποίησης και τα προγράμματα ανάλυσης για τηλύση του αντίστροφου προβλήματος. Το Κεφάλαιο 4 περιγράφει την αναζήτηση, εξόρυξη και αυτόματη ανάλυση δεδομένων από παρατηρησιακές αστρονομικές επισκοπήσεις και την εφαρμογή του κώδικα τεχνητών νευρωνικών δικτύων EBAI. Το δεύτερο μέρος επικεντρώνεται στην αναλυτική μελέτη επιλεγμένων στενών διπλών συστημάτων W UMa με ιδιαίτερο ενδιαφέρον. Σε όλα τα επιλεγμένα συστήματα παρουσιάζεται η φωτομετρική τους μελέτη κάτω από το φως νέων BV RcIc παρατηρήσεων, η μελέτη της περιόδου, το εξαγόμενο μοντέλο σε συνδυασμό με φασματοσκοπικά δεδομένα, ο προσδιορισμός τροχιακών και φυσικών παραμέτρων και η θέση τους σε εξελικτικά διαγράμματα. Επίσης γίνεται η διερεύνηση του προτεινόμενου μοντέλου για μοναδικότητα στο χώρο των λύσεων μέσα από σάρωση με εισαγωγή διαταραχών ή άλλων στατιστικών μεθόδων και ο στατιστικός προσδιορισμός των σφαλμάτων των παραμέτρων. Συγκεκριμένα στο Κεφάλαιο5 παρουσιάζεται το ενοποιημένο μοντέλο του συστήματος TY Boo δύο κηλίδων που ερμηνεύει τη συμπεριφορά του την περίοδο 1969-2011 και τη μελέτη της περιόδου του. Σύμφωνα με αυτό το σύστημα TY Boo ανήκει στην υποκατηγορία W των W UMa με μικρό βαθμό επαφής f = (7.6 ±0.8)% και η μακρόχρονη μελέτη της περιόδου του δείχνει μακροχρόνια μείωση (dP/dt = −3.65x10^−8 d yr^−1 ) και μία περιοδικότητα (P3 = 58.9yrs, A = 0.0254 days)η οποία, χωρίς να αποκλείεται η παρουσία τρίτου σώματος, ερμηνεύεται με ενεργό μαγνητικό κύκλο που προκαλεί την εμφάνιση κηλίδων.Στο Κεφάλαιο 6 παρουσιάζεται για πρώτη φορά η λεπτομερής ανάλυση του συστήματος WUMa, FI Boo το οποίο ταξινομείται στην υποκατηγορία W, με βαθμό επαφής f = (50.15 ±8.10) %, κάτω από την παρουσία τρίτου σώματος το οποίο μπορεί να παίζει σημαντικό ρόλο στη δημιουργία και την εξέλιξή του. Σύμφωνα με το προτεινόμενο μοντέλο προσδιορίζονται οι μάζες Mh =0.40 ± 0.05 Msun , Mc =1.07 ± 0.05 Msun , και οι θερμοκρασίες Th = 5746±33Κ, Tc = 5420±46 Κ των αστέρων-μελών του καθώς και των προγεννητόρων τους (1.71 ±0.10 Msun και 0.63 ± 0.01 Msun , αντίστοιχα) και διερευνάται το εξελικτικό στάδιο του αστέρα με τη μεγαλύτερη μάζα μέσα από ισόχρονες.Στο Κεφάλαιο 7 διερευνάται σε βάθος το σύστημα σε επαφή V1003 Her, το οποίο χαρακτηρίζεται από μεταβολή μικρού πλάτους, με πολλαπλά μοντέλα για τα οποία ελέγχεται η σταθερότητα των με ανεξάρτητες μεθόδους. Το επικρατέστερο από αυτά δείχνει ότι το σύστημα είναι W UMa με βαθμό επαφής f = (36±10) %, με ασυνήθιστα άνισες θερμοκρασίες μεταξύ των αστέρων του 550 Κ, και λόγο μαζών q = 0.373. Η μικρή του κλίση i = 38^o ±1^ο το καθιστά ένα από τα μεγαλύτερης μάζας στην υποκατηγορίας W.Στο Κεφάλαιο 8 εξετάζεται η φύση του διπλού συστήματος HI Dra, η λεπτομερής ανάλυση του οποίου δείχνει ότι είναι W UMa με μικρό βαθμό επαφής f = (24 ± 4) % και διαφορά θερμοκρασίας μεταξύ των αστέρων του 330 Κ. Προτείνονται και διερευνώνται εξονυχιστικά δύο μοντέλα με κηλίδες από τα οποία επικρατέστερο, με ψυχρή κηλίδα πάνω στον μικρότερης μάζας και ψυχρότερο αστέρα- τον τοποθετεί στην υποκατηγορία Α. Προσδιορίζονται οι φυσικές παράμετροι των μελών του (M = 1.72 ± 0.08Msun , Mc = 0.43 ± 0.02 Msun , Rh =1.98 ± 0.03Rsun , Rc = 1.08 ± 0.02 Rsun , Lh = 9.6 ± 0.1 Lsun , Lc = 2.4 ± 0.1 Lsun ) και των προγεννητόρων τους (1.11 ± 0.03 Msun και 2.25 ± 0.07 Msun, αντίστοιχα) και προσεγγίζεται η ηλικία του συστήματος σε 2.4 Gyr .Τέλος στο Κεφάλαιο 8 παρουσιάζονται τα πρώτα αποτελέσματα από τις φωτομετρικές παρατηρήσεις με το τηλεσκόπιο Αρίσταρχος 2.3 m, διπλών εκλειπτικών συστημάτων με ιδιαίτερο ενδιαφέρον που ανακαλύφθηκαν ή παρατηρήθηκαν από την διαστημική αποστολή Kepler με περιόδους περιφοράς < 0.45 d, τα οποία παρουσιάζουν ασυμμετρίες στην καμπύλη φωτός, χρονικές μεταβολές των εκλείψεων των μελών τους ή είναι εν δυνάμει τριπλά συστήματα. Τα πρώτα αποτελέσματα αφορούν τα συστήματα KIC 11246163 και KIC 4563150τα οποία ταξινομούνται ως συστήματα τύπου W UMa, W υποκατηγορίας με πιθανό τριτο συνοδό. / The study of eclipsing binary systems remains one of the most powerful research fields in stellar astrophysics because it provides the primary source of calculating fundamentals properties of stars (masses, radii, temperatures) and every form of stellar activity (spots, accreting discs, pulsations) through photometry and spectroscopy or/and through the study of long-term variability of their period. Additionally it allows testing of stellar structure and evolution theories and the prediction of third body companions of stellar or sub-stellar origin. This thesis is focused on the study of W UMa type eclipsing binaries containing main sequence stars in overcontact configuration with short periods and,therefore the small angular momentum. The aim is both the multiband observational study, analysis and investigation of WUMa systems of particular interest but also the development of modeling methodology in order to extract the maximum information and to determine a detailed assessment of the parameter uncertainties through the application of modern statistical methods. The first part of the Doctoral Thesis outlines the theoretical framework for describing eclipsing binary stars. Chapter 1 refers to the physics and geometry of orbits and components, the description of the Roche model that led to the classification based on equipotential surfaces, the computation of the total radiated flux in the direction of the observer by including all the corrections needed and the description of systems dynamics as manifested by the observed change of their period. Chapter2 presents the photometric observations made during this research and the automated methods of processing and analysis (pipelines) which were developed. Chapter 3 sketches the modern modeling and analysis software techniques for the solution of inverse problem(Differential Corrections, Levenberg-Marquardt, Downhill Simplex, Genetic Algorithms,Heuristic Scanning, Bootstrap resampling, Metropolis –Hasting Markov Chain MonteCarlo), their implementation to programs developed as part of the present thesis and their application to real data. These also represent the methodology of the analyses implemented for the study of the WUMa systems, described in Part 2. Finally, Chapter4 describes the development of a pipeline for the exploration, extraction and automatic analysis of data from astronomical surveys and its application to ASAS database. In the same chapter the first results from the training and validation of the Artificial Neural Network (ANN), EBAI, and the best topology for the ANN are presented.The second part focuses on the detailed study of selected W UMa systems with particular interest. This includes: the new multiband photometric observations, the longterm period variation, the exported model from photometric and spectroscopic data (from the literature), the determination of orbital and physical parameters and their position in evolutionary diagrams, the investigation of the proposed model for uniqueness in the parameter space through heuristic scanning with parameter kicking or other statistical methods- and the statistical determination of the uncertainties of the derived parameters.In Chapter 5, new CCD four-color light curves of TY Boo made on eight nights over2010–2011 were analyzed in comparison with historical light curves obtained from 1969through 2011. The light curves could all be represented by a unique geometry and by wavelength consistent phototometric parameters of a two-spot model on either stellar component. It is confirmed that TY Boo is a shallow W-type contact binary system with a degree of contact factor of f = 7.6 ± 0.8%. A period investigation based on all available data shows a long-term decrease (dP/dt = −3.65 ×10−8 days yr−1 ) and an oscillation (P3 = 58.9 yr, A = 0.0254 days). Without ruling out the presence of a tertiary companion, the weight of evidence points to an active cyclic magnetic activity that causes spot formation rather than an unseen companion. Mass transfer between the components and angular momentum loss are also considered as possible mechanisms.In Chapter 6, a detailed analysis of the interesting W UMa binary FI Boo in view of the spectroscopic signature of a third body through photometry, period variation, and a thorough investigation of solution uniqueness is presented. We obtained new BVRcIc photometric data that, when combined with spectroscopic data, enable us to analyze the system FI Boo and determine its basic orbital and physical properties through PHOEBE,as well as the period variation by studying the times of the minima. This combined approach allows us to study the long-term period changes in the system for the first time in order to investigate the presence of a third body and to check extensively the solution uniqueness and the uncertainties of derived parameters. Our modeling indicates that FIBoo is a W-type moderate (f = 50.15% ± 8.10%) overcontact binary with component masses of Mh = 0.40 ± 0.05 M and Mc =1.07 ± 0.05 M , temperatures of Th = 5746 ±33 K and Tc = 5420 ± 56 K, and a third body, which may play an important role in the formation and evolution. The results were tested by heuristic scanning and parameter kicking to provide the consistent and reliable set of parameters that was used to obtain the initial masses of the progenitors (1.71 ± 0.10 M and 0.63 ± 0.01 M , respectively). We also investigated the evolutionary status of massive components with several sets of widely used isochrones.In Chapter 7, an extensive analysis of the low amplitude, contact binary V1003 Her is presented, based on the new VRc Ic , CCD photometric light curves in combination with published radial velocity (RV) curves. We investigate the stable configurations for the system with two independent methods and modeling tools: PHOEBE, ROCHE, via heuristic scanning and genetic algorithms, although the very low inclination of the system can place limitations. All methods indicate that V1003 Her is most likely in overcontact state with unequal components with temperature difference of 550 K, a mass ratio of q= 0.373 and a contact degree of 36 ± 10 %. As it is viewed at the very low inclination of i ∼ 38^◦ ± 1^◦ , if its configuration is confirmed, it will be among the most massive W-subtype of W UMa systems. This conclusion is also supported by other published models.However, in order to conclude reliable physical properties of the system, the high-precise based-ground photometry (or satellite photometry) and spectroscopic follow-up of V1003Her is required.In Chapter 8, a detailed investigation of the low-amplitude contact binary HI Dra is presented, based on the new VRc Ic CCD photometric light curves (LCs) combined with published radial velocity (RV) curves. Our completely covered LCs were analyzed using PHOEBE and revealed that HI Dra is an overcontact binary with low fill-out factor f = 24 ± 4 (%) and temperature difference between the components of 330 K.Two spotted models are proposed to explain the LC symmetry, between which the A subtype of W UMa type eclipsing systems, with a cool spot on the less massive and cooler component, proves to be more plausible on evolutionary grounds. The results and stability of the solutions were explored by heuristic scan and parameter perturbation to provide a consistent and reliable set of parameters and their errors. Our photometric modeling and RV curve solution give the following absolute parameters of the hot and cool components, respectively: Mh = 1.72 ± 0.08 Msun and Mc = 0.43 ± 0.02 Msun , Rh =1.98 ± 0.03 Rsun and Rc = 1.08 ± 0.02 Rsun , and Lh = 9.6 ± 0.1 Lsun and Lc = 2.4 ± 0.1Lsun . Based on these results the initial masses of the progenitors (1.11 ± 0.03 Msun and2.25 ± 0.07 Msun , respectively) and a rough estimate of the age of the system of 2.4 Gyr are discussed.Finally, in Chapter 9, our first results from ground based follow up photometric observation of interesting eclipsing binary systems (EBs) from Kepler field are presented.The program was launched in 2013 with the 2.3 m Aristarchos telescope at Helmos Observatory, Greece including eclipsing binary systems with periods < 0.45d and Kp (mag)=12.6-16 mag. The included targets in this program show light curve asymmetries,Eclipse Timings Variation or they are third body candidates. Modern analysis techniques such as heuristic scanning with parameter perturbation and genetic algorithm(PIKAIA), enable to reveal and optimize the astrophysical parameters of selected EBs.The results from BVRI photometry for the third body candidates, WUMa eclipsing binary systems of W-subtype, KIC11246163 and KIC4563150, are presented for the first time, as well as conclusions derived so far.
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Resolution and characterization of subgroups of Gardnerella vaginalis and description of the vaginal microbiota of women with preterm premature rupture of membranes2015 February 1900 (has links)
The vaginal microbial community is critical to a woman’s health and the health of her family. Bacterial vaginosis (BV) is a polymicrobial syndrome characterized by a shift of the vaginal microbiota from a Lactobacillus dominated community to a dense biofilm containing a complex mixture of organisms. Although BV is an important risk factor for poor reproductive health outcomes, the etiology of BV is poorly understood.
Gardnerella vaginalis is a hallmark species of BV. Phylogenetic analysis of cpn60 universal target sequences from metagenomic studies of the vaginal microbiome and from G. vaginalis isolates resolved four subgroups within the species. This subdivision, supported by whole genome similarity comparisons, demonstrated that these subgroups might represent different species. Among a group of African women, only G. vaginalis subgroup B was significantly more abundant in women with BV relative to women with Nugent scores not consistent with BV. To characterize the subgroups further, several phenotypic and molecular factors of G. vaginalis subgroups were assessed. Proteomic profiles of isolates within each subgroup formed unambiguous clusters. Sialidase gene sequences were detected in all subgroups, however enzymatic activity was detected only in subgroup B. Two isolates of subgroup B isolates (N153 and N101) were incapable of growth in 7% CO2. Given the well-known relationship between an anaerobic microbiota and BV, anaerobic isolates of G. vaginalis are potentially important players in the vaginal microbial community. To determine genome content differences that could account for the phenotypic difference, whole genome sequences of four G. vaginalis subgroup B isolates representing facultative and anaerobic phenotypes were determined. Comparison of genomes led to the identification of genes predicted to encode proteins involved in cell wall biogenesis and protection from oxidative damage that might account for the observed phenotypes.
The cpn60 universal target based methodology that improved resolution of the vaginal microbiota including G. vaginalis was applied in a prospective study of the vaginal microbiome of women with preterm premature rupture of membranes (PPROM). The objectives were to characterize the vaginal microbiota of women following PPROM, and to determine if microbiome composition at the time of rupture predicts latency duration and perinatal outcomes. Only 13/70 samples collected from 36 women were dominated by Lactobacillus spp., the expected profile for healthy women, while Megasphaera type 1 and Prevotella spp. were detected in all samples. Microbiome profiles at the time of membrane rupture did not cluster by gestational age at PPROM, or latency duration. Microbial profiles were unstable over the latency period, with dramatic shifts in composition between weekly samples, and an overall decrease in Lactobacillus abundance. Mollicutes were detected by PCR in 81% (29/36) of women, and these women had significantly lower gestational age at delivery and correspondingly lower birth weight infants than Mollicutes negative women.
Taken together, the results presented in this thesis demonstrate the value of high resolution profiling of the vaginal microbiome using cpn60 UT sequences. The resolution of subgroups within G. vaginalis has potentially significant implications for women's health diagnostics, requiring a shift away from considering G. vaginalis as a single entity. The PPROM study provides foundational information that may lead to the identification of informative sequence patterns, providing clinicians with better tools for expectant management following PPROM.
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Re-imagining the theology of human sexuality in the Methodist Church : the use of narrative in theological methodologyPrice-Tebbutt, Nicola Vernier January 2016 (has links)
This thesis proposes the development of a narrative methodology in the British Methodist Church. Such a methodology embraces and communicates both felt experience and critical theological thinking, thus producing and presenting a theology that might have a constructive transformative impact on wider society. In chapter one I explore the ways in which the Church speaks in public, identify some of the challenges it faces, and consider four models of engagement. If the Church is to engage in public discourses then I argue that its words need to be relevant and connect with people’s experiences. To ground the thinking I focus on the context of the British Methodist Church and explore how the Church engages in theological reflection through the lens of its thinking on issues of human sexuality. Chapter two reviews how theological reflection is undertaken in the British Methodist Church. I describe how the Methodist Quadrilateral of Scripture, tradition, reason and experience remains a foundational framework for theological reflection within the Methodist Church and consider the impact of institutional processes and the ways in which the Methodist people actually engage with theological thinking. The third and fourth chapters focus on how the British Methodist Church has produced its theology of human sexuality, giving particular attention to the use of personal and sexual stories in this process. I find that whilst there has been a desire to listen to the stories of the Methodist people, there has not been a corresponding interrogation or analysis of their stories so as to enable robust and constructive theological reflection on these experiences. Using resources from Foucauldian approaches to discourse analysis, I critique key statements and the processes involved in their production, offering an analysis of this body of theological thinking and indicating where possibilities for alternative ways of thinking and acting arise. The proposed methodology draws upon resources from social science methodologies, and in chapter five I look at the use of personal experience and relevant strategies of inquiry that prompt reflection on the hermeneutical process and employ narrative approaches in undertaking, analysing and presenting research. The exploration shows that qualitative research methodologies offer resources and methods of inquiry that could help the Church to engage with personal stories in its theological thinking in a robust, interrogative and imaginative way. In chapter six an examination of story and narrative is undertaken, to show how they have been understood as ways of knowing and how they relate to theological inquiry. Whilst acknowledging some of the limitations of narrative, I indicate how it offers constructive possibilities for theological reflection and could be a means for the British Methodist Church to engage in public discourse. This is explored further in chapter seven, which looks in more detail at how the British Methodist Church has used narrative in its theological thinking, and outlines areas requiring further attention in order for a narrative theological methodology to be developed, namely: attention to the question ‘whose experience?’; investigation of issues of power and the dynamics involved in the process of the production of theological thought; how personal stories and experiences are interrogated and how narrative is constructed; and how narrative might be employed within the Methodist Quadrilateral. The final chapter considers the advantages and limitations of such an approach, whether the development of such a method is possible in the Methodist Church today and its potential for helping the Church to engage in public discourse more effectively. I argue that this methodology can provoke new theological insights and enable new ways of being in the world.
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Catholic chaplains on the Western Front, 1915-1919 : Lancashire's pivotal roleBellis, Stephen January 2015 (has links)
An examination of the spiritual and temporal roles of Catholic chaplains in WW1 in France and Belgium. All the formative influences at home are assessed from religious, political, social, and geographic perspectives. The roles of the bishops in England and Ireland are reviewed and how their post war ambitions were interpreted at the Front are explained. Lancashire's traditional Catholic strength makes it a significant contributor, not least as the fulcrum between Irish and English catholics.
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Reflecting theologically on the impact of HIV in Edinburgh, with particular reference to infected people, health and social care professionals, Scottish churches and local agency, Waverley CareChatterley, Marion Frances January 2017 (has links)
This thesis discusses the impact of HIV in Edinburgh on infected individuals, professionals and the Scottish churches. It is grounded in contextual practical theology, offering reflexive responses to evidence gleaned from oral histories. The thesis documents the development of a local agency, Waverley Care, exploring the influences and pressures that contributed to its distinctive ethos. The author was employed as chaplain to people living with HIV from 2000 – 2016; the pastoral and professional relationships that emerged from that ministry form the foundation for the research. Unstructured interviews were conducted and Interpretative Phenomenological Analysis was used to analyse, interpret and reflect on the resultant material. Personal stories and perspectives were shared, both by people living with HIV and by professionals in the field. The impact of living with HIV is shown by discussing issues such as the ongoing impact of HIV-related stigma and the challenges associated with living long-term with the condition. Attention is paid to the challenges arising as a result of multiple bereavements and the resultant spiritual questions that emerge. The impact on physicians is also evidenced, in particular the transition from treating patients before the advent of effective medication, to the situation in 2016 when HIV has been re-classified as a chronic illness. Recommendations on areas of ongoing concern are made for decision makers in public health, the churches and Waverley Care. Deep reflective analysis is offered, using the Stations of the Cross and models from bereavement work to provide frameworks for understanding. The contribution of the Scottish churches to the establishment of support services is recognised; the churches’ influence, both positive and negative on discourse on human sexuality is discussed. The research evidences the impact of the provision of spiritual care within a secular agency, showing that it is possible to create sacred space and to deliver a sacramental ministry within a non-church setting.
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