Detta arbete har syftat till att ta reda på vad som är viktigt att tänka på vid utformning av instruktioner för CAD-användare. Som praktikfall har en studie gjorts på Volvo IT där deras instruktioner för CAD/CAM/CAE-systemet CATIA V5 har granskats. Undersökningen mynnade ut i en användarstudie där erfarna användare av systemet fick möjlighet att diskutera den support som finns i dagsläget samt ställa krav på framtida instruktioner. Kraven som togs fram har legat till grund för riktlinjer för hur morgondagens instruktioner skulle kunna göras mer användaranpassade. Några områden som är viktiga att ta hänsyn till är bland annat: att ta tillvara på användarnas erfarenhet, involvera användarna vid framtagandet av instruktionerna, ta reda på hur instruktionenrna läses samt skapa rubrikter som underlättar informationssökning för användarna.

The effect of variable inertia flywheel (VIF) on the driving speed fluctuation, and residual vibration of high speed machine systems is investigated in this thesis. Different variable inertia flywheels are proposed to an experimental purpose roller gear cam system and a commercial super high speed paper box folding machine. The effects of time varying inertia and intermittent cam motion on the dynamic responses of different high speed cam droved mechanism systems are simulated numerically. The nonlinear time varied system models are derived by applying the Lagrange¡¦s equation and torque-equilibrium equations. The dynamic responses of these two nonlinear systems under different operating speed are simulated by employing the 4th order Runge-Kutta method. The effects of VIF parameters on the dynamic responses, i.e. the output precision, variation of motor speed, and torque, during the active and dwell periods for these two systems are studied and discussed. The difference between the dynamic responses of constant inertia and variable inertia flywheel systems are also compared. The feasibility and effectiveness of depression of driving speed and torque fluctuations by analying variable inertia flywheel has also been demonstrated.

This thesis presents a geometry design method to generate the surfaces of the globoidal cam with the conical roller follower. Based on the trace of the rigid body and the theory of differential geometry, the conjugate surfaces can be the offset surfaces of the ruled surface. With different roller¡¦s axial height, its radius and the meshing vector also be changed. For this reason, the contact points on the outward roller are hard to find. To overcome this problem, we propose the triangular graph with meshing angle, it can present the vector quantity caused from the motion angle. We replace it into the procedures of the rigid body transformation method to derive the cam surfaces with the conical roller follower. Furthermore, two models with modified sine and constant velocity motion curves are generated and analyzed.

Rotary tables are generally regarded as the forth axis of machining tools. Traditionally, gear sets are used as reducers in the rotary tables. In order to improve the positioning accuracy, load and efficiency of rotary tables, a rotary table which applies the roller gear cam reducer is proposed. From the deduction of the theory, applications of roller gear cam reducers in the industries can be achieved. This thesis is focused on developing the procedure as follows: Firstly, the type of roller gear cam reducer and design parameters are identified. Secondly, the mechanical characteristics of the device are analyzed. Finally, a rotary table is designed and implemented to investigate the performance of the of the roller gear cam rotary table.

Recently, many industries pursue the goal of automatic high-speed assembly and manufacturing. So how to meet the requirement of high-precision and high-speed automatic assembly equipment is an important issue. In automatic assembly equipment, the high-speed indexing devices have been widely used because of their features of high precision, no backlash, and compactness. With increasing operating speeds, the problems of shortage of motor power, poor indexing accuracy, vibration, and noise shall be solved. The torque compensation mechanism that is to be developed here is applied to keep motors operating at constant speeds by compensating the required torque. In previous researches, the researchers all devote to study torque compensation based on synchronous time chart. In this paper, it is aimed at compensation of the time control chart according the point of view of energy and the system model is built to simulate dynamic response of the system. Through the results of simulation and experiment, we will discover the relations between the compensation time chart and parameters about the high-speed indexing devices. It is expected to improve the precision of indexing devices according to those effective compensation time control charts.

This dissertation focuses on developing algorithms that generate tool paths for free-form surfaces based on accuracy of desired manufactured part. A manufacturing part is represented by mathematical curves and surfaces. Using the mathematical representation of the manufacturing part, we generate reliable and near optimal tool paths as well as cutter location (CL) data file for postprocessing. This algorithm includes two components. First is the forward-step function which determines maximum distance called forward- step between two cutter contact (CC) points with given tolerance. This function is independent of the surface type and is applicable to all continuous parametric surfaces that are twice differentiable. The second component is the side-step function which determines maximum distance called side-step between two adjacent tool paths with a given scallop height. This algorithm reduces manufacturing and computing time as well as the CC points while keeping the given tolerance and scallop height in the tool paths. Several parts, for which the CC points are generated using the proposed algorithm, are machined using a three axes milling machine. As part of the validation process, the tool paths generated during machining are analyzed to compare the machined part and the desired part.

<p> </p><p>Detta arbete har syftat till att ta reda på vad som är viktigt att tänka på vid utformning av instruktioner för CAD-användare. Som praktikfall har en studie gjorts på Volvo IT där deras instruktioner för CAD/CAM/CAE-systemet CATIA V5 har granskats. Undersökningen mynnade ut i en användarstudie där erfarna användare av systemet fick möjlighet att diskutera den support som finns i dagsläget samt ställa krav på framtida instruktioner. Kraven som togs fram har legat till grund för riktlinjer för hur morgondagens instruktioner skulle kunna göras mer användaranpassade.</p><p>Några områden som är viktiga att ta hänsyn till är bland annat: att ta tillvara på användarnas erfarenhet, involvera användarna vid framtagandet av instruktionerna, ta reda på hur instruktionenrna läses samt skapa rubrikter som underlättar informationssökning för användarna.</p><p> </p>

Inaug.-Diss.--Erlangen. / Lebenslauf. "Wichtigere benutzte Werke": p. [vi]-viii.

Calmodulin (CaM) is a highly conserved protein able to bind Ca2+. When Ca2+ is bound the protein can bind and activate further proteins with several individual functions. CaM switches to a more open conformation when Ca2+-bound and is able to do so at a high rate. Little is known about the conformational switches between apo and Ca2+-bound states. A hypothesis suggests that protonation/deprotonation of a histidine side-chain is part of the answer and thus the dynamics of CaM would be pH dependent. This was further investigated in this thesis. Methods to carry out the project included protein expression of isotope labelled CaM-TR2C E140Q, standard protein purification and protein adapted Nuclear Magnetic Resonance (NMR) spectroscopy. The results suggest that CaM-TR2C E140Q is likely to depend on pH and that histidine 107 (H107) may have a central role in the conformational changes observed. At lower pH it was also suggested that CaM-TR2C E140Q obtained a more open conformation with weakened intramolecular interactions and that the tertiary structure of CaM-TR2C E140Q may have been disrupted. / Calmodulin (CaM) är ett, till hög grad konserverat protein med möjlighet att binda in Ca2+. Då Ca2+ är bundet kan proteinet binda och aktivera ytterligare protein med olika enskilda funktioner. CaM byter med hög hastighet till en mer öppen konformation då Ca2+ binder. Lite vetskap finns kring hur konformationsändringarna mellan apo-form och Ca2+-bunden form går till. En hypotes föreslår att protonering/deprotonering av en histidin-sidokedja kan vara en del av svaret och att CaMs dynamik därför bör vara beroende av pH. Detta undersöktes vidare i detta examensarbete. Metoder som användes för att genomföra projektet inkluderar proteinuttryck av isotopinmärkt CaM-TR2C E140Q, standardiserad proteinrening och proteinanpassad kärnmagnetisk resonans (NMR) spektroskopi. Resultaten föreslår att konformationsändringarna av CaM-TR2C E140Q troligen är pH-beroende och att histidin 107 (H107) kan ha en central roll vid dessa ändringar. Vid lägre pH föreslås att CaM-TR2C E140Q antar en mer öppen konformation med försvagade intramolekylära interaktioner och att tertiärstrukturen av CaM-TR2C E140Q kan ha blivit upplöst.

published_or_final_version / Mechanical Engineering / Master / Master of Philosophy