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Compromisso dos pesquisadores com Comitês de Ética em Pesquisa nas dissertações e teses envolvendo seres humanos do Programa de Pós-Graduação em Ciências da Saúde da Universidade de Brasília no período agosto 1996 – dezembro 2006Maluf, Fabiano January 2007 (has links)
Dissertação (mestrado)—Universidade de Brasília, Faculdade de Ciências da Saúde, 2007. / Submitted by Luis Felipe Souza (luis_felas@globo.com) on 2008-12-11T17:16:35Z
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Dissertacao_2007_FabianoMaluf.pdf: 1123419 bytes, checksum: db84466ee8b85a3d3190409c2ca17fd1 (MD5) / A avaliação ética dos protocolos de pesquisa, quando há o envolvimento de seres
humanos, por um Comitê de Ética em Pesquisa (CEP) é considerada um instrumento de controle social capaz de evitar que abusos sejam cometidos e assegurar o respeito à dignidade e integridade dos participantes de pesquisa.
O presente trabalho tem por objetivo avaliar o compromisso ético dos pesquisadores mestrandos e doutorandos) e orientadores do Programa de Pós-Graduação em Ciências da Saúde, da Faculdade de Ciências da Saúde, da Universidade de Brasília com relação ao envio de projetos de mestrado e doutorado à CEP, no período compreendido entre agosto de 1996 a dezembro de 2006, utilizando como referencial teórico a Resolução 196/96, que estipula as diretrizes e normas regulamentadoras de pesquisas envolvendo seres humanos. O procedimento
metodológico consistiu na identificação das dissertações e teses que: envolviam seres humanos e tinham em anexo o parecer de um CEP; as que mencionavam o envio do projeto e aprovação do CEP; e as que, embora não tivessem anexado nem mencionado a aprovação por um CEP, possuíam, nos arquivos selecionados o protocolo de pesquisa avaliado. Identificou-se, também, a presença do Termo de Consentimento Livre e Esclarecido (TCLE) junto aos trabalhos investigados. Osr resultados encontrados revelam que 73,72% das dissertações e 80% das teses, que envolviam seres humanos, foram encaminhadas à CEP no período estudado. Observou-se um salto quantitativo ocorrido no ano de 2001 para as dissertações e no ano 2000 para as teses prevalecendo, a partir destas datas, número
significativamente superior de trabalhos encaminhados à CEP. Esses resultados
apontam que, durante o desenvolvimento do Programa de Pós-Graduação, houve
uma crescente conscientização e comprometimento ético dos pesquisadores
( mestrandos e doutorandos ) e orientadores demonstrando a relevância da construção de uma cultura Bioética necessária para a formação acadêmica e profissional dos egressos.
________________________________________________________________________________________ ABSTRACT / The ethical assessment of research protocols made by an Institutional Review Board (IRB), when there is an envolvement of human beings, is considered a tool of social control, capable of preventing abuse and assuring respect for participants dignity and integrity. The present work aims to evaluate ethical commitment among researchers (master´s and doctorate) and their advisors in the Health Sciences Postgraduate Program of the Health Sciences Faculty at the University of Brasilia, regarding the projects for masters degree and doctorate, within the period between august 1996 and december 2006, using as a theoretical reference Resolution 196/96, which rules research involving human beings. The method utilized for that consisted of identification of papers which included human beings and either 1) had, annexed, an
IRB approval report, or 2) mentioned such approval by an IRB, or 3) those which, although having neither of the conditions, presented the assessed research protocol.
The existence of an Informed Consent (IC) was also identified. Results showed that
73.72% of masters dissertations and 80% of doctorate theses involving human beings were submitted to an IRB within the period. A higher number was observed in the year of 2001 for dissertations and 2000 for theses and, from these dates on, more papers were sent to IRB. These data suggest that, during the Postgraduate Program development, there was crescent awareness and ethical commitment among researchers (master´s and doctorate) and advisors, showing the relevance given to the construction of a bioethical culture, necessary for adequate academic and professional formation of students.
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O papel das rotas e da obten??o de informa??es sobre a efici?ncia no forrageio de dinoponera quadriceps em ambiente naturalAzevedo, Dina Lillia Oliveira de 20 August 2009 (has links)
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Previous issue date: 2009-08-20 / Conselho Nacional de Desenvolvimento Cient?fico e Tecnol?gico / Investigamos nesta pesquisa, o papel das rotas e da obten??o de informa??es sobre a efici?ncia no forrageio de Dinoponera quadriceps. Foram observadas duas col?nias numa ?rea de mata atl?ntica secund?ria na FLONA-ICMBio de N?sia Floresta, Estado do Rio Grande do Norte, pelo menos uma vez por semana. Inicialmente, observamos as oper?rias, desde a sa?da do ninho at? o retorno, sem qualquer tipo de manipula??o, numa segunda fase, introduzimos uma placa de acr?lico (100 x 30 x 0,8 cm) diante da entrada observada. Todo o registro comportamental foi feito com a t?cnica do focal time sampling e todas as ocorr?ncias, como complementar; os focais eram de 15 min, com registro a cada minuto, e intervalo de 5 min entre eles. As oper?rias gastaram a maior parte do tempo fora do ninho no comportamento de forrageio. O tempo fora do ninho e a dist?ncia percorrido mostra uma rela??o positiva. Estas vari?veis influenciaram na propor??o do alimento, que requereu mais tempo e dist?ncia na busca. A propor??o tamb?m interferiu no tempo que a oper?ria ficava no ninho antes de uma nova viagem, maior propor??o menor tempo no ninho. Durante toda a pesquisa, as oper?rias individuais demonstraram fidelidade ? rota e a setores na ?rea de uso, mesmo na presen?a da placa, na qual elas desviavam e continuavam seu curso. As caracter?sticas no forrageio quanto ao tempo, dist?ncia, rota fixa e flexibilidade para desviar de obst?culos, apresentadas pelas oper?rias indicam que as decis?es ocorrem em n?vel individual e ? eficiente em rela??o ao balan?o custo-benef?cio. A estrat?gia adotada se encaixa na teoria do ponto central e no teorema do valor marginal, e demonstra ser flex?vel ? presen?a de informa??es novas, o que indica que as oper?rias s?o capazes de aprender novas pistas do ambiente para orient?-las / In this study, we investigated the role of routes and information attainment for the queenless ant species Dinoponera quadriceps foraging efficiency. Two queenless ant colonies were observed in an area of Atlantic secondary Forest at the FLONA-ICMBio of Nisia Floresta, in the state of Rio Grande do Norte, northeastern Brazil, at least once a week. In the first stage of the study, we observed the workers, from leaving until returning to the colony. In the second stage, we introduced a acrylic plate (100 x 30 x 0,8 cm) on a selected entrance of the nest early in the morning before the ants left the nest. All behavioral recordings were done through focal time and all occurence samplings. The recording windows were of 15 minutes with 1 minute interval, and 5 minute intervals between each observation window. Foraging was the main activity when the workers were outside the nest. There was a positive correlation between time outside the nest and distance travelled by the ants. These variables influenced the proportion of resource that was taken to the nest, that is, the bigger its proportion, the longer the time outside and distance travelled during the search. That proportion also influenced the time the worker remained in the nest before a new trip, the bigger the proportion of the item, the shorter was the time in the nest. During all the study, workers showed fidelity to the route and to the sectors in the home range, even when the screen was in the ant?s way, once they deviated and kept the route. The features of foraging concerning time, distance, route and flexibility to go astray by the workers indicate that decisions are made by each individual and are optimal in terms of a cost-benefit relation. The strategy chosen by queenless ants fits the central place foraging and marginal value theorem theories and demonstrate its flexibility to new informations. This indicates that the workers can learn new environmental landmarks to guide their routes
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Efeitos do kinesiotaping no quadro ?lgico e no desempenho neuromuscular de portadores da s?ndrome da dor femoropatelarMelo, Samara Alencar 20 December 2016 (has links)
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Previous issue date: 2016-12-20 / A S?ndrome da Dor Femoropatelar (SDFP), definida como dor anterior ou retropatelar, ? uma das disfun??es m?sculo-esquel?ticas mais frequentes no joelho que acomete, sobretudo, a popula??o feminina e cujo tratamento apresenta-se controverso. Objetivo: Analisar os efeitos imediatos e tardios da aplica??o do Kinesio Taping (KT) na atividade eletromiogr?fica do m?sculo vasto medial obl?quo (VMO), no desempenho isocin?tico do quadr?ceps femoral e na dor de sujeitos portadores da SDFP. M?todos: Ensaio cl?nico, randomizado e cego, no qual 54 volunt?rias, com idade m?dia de 23,70 ? 3,76 anos, foram distribu?das aleatoriamente em tr?s grupos e realizaram um dos seguintes protocolos: (1) grupo controle - permaneceram em repouso; (2) grupo com tens?o - aplica??o do KT com tens?o na regi?o do VMO; (3) grupo sem tens?o - aplica??o do KT sem tens?o, na mesma regi?o. Todas as volunt?rias foram submetidas ? avalia??o da intensidade da dor, da atividade eletromiogr?fica do VMO e VL e dos par?metros dinamom?tricos em tr?s momentos distintos: antes da aplica??o do KT, imediatamente ap?s e 72h depois da aplica??o. A an?lise estat?stica foi realizada por meio do SPSS (vers?o 20.0). Foi utilizada uma ANOVA de modelo misto para verificar diferen?as intra e intergrupo, com n?vel de signific?ncia de 5% (p ? 0,05). Resultados: Houve diferen?a significativa intergrupo na intensidade da dor entre o grupo sem tens?o e o grupo controle, ap?s 72h. Com rela??o ?s vari?veis dinamom?tricas, n?o houve diferen?a entre os grupos avaliados para o pico de torque normalizado pelo peso corporal, pico de torque m?dio, pot?ncia m?dia e trabalho total. Tamb?m n?o foram observadas diferen?as no que se refere ?s vari?veis eletromiogr?fica: raz?o VMO/VL e tempo de in?cio da ativa??o do VMO em rela??o ao VL, em cadeia aberta e fechada. Conclus?o: O Kinesio Taping, aplicado no vasto medial obl?quo, n?o promove altera??es imediatas e nem tardias no desempenho isocin?tico nem nos par?metros eletromiogr?ficos de portadores da S?ndrome da Dor Femoropatelar. Entretanto, foi observada uma redu??o da dor no grupo que aplicou o KT sem tens?o, ap?s 72 horas da sua aplica??o. / Patellofemoral pain syndrome (PFPS) is defined as anterior or retropatellar pain. It is one of the most frequent musculoskeletal dysfunctions in the knee, that affects mainly, the female population and whose treatment is controversial. Objective: To analyze the immediate and late effects of Kinesio Taping (KT) in the electromyography activity of the vastus medialis obliquus (VMO), in the isokinetic performance of the quadriceps femoris and the pain of subjects with PFPS. Methods: Randomized clinical trial, in which 54 volunteers, with a mean age of 23.70 ? 3.76 years were randomized into three groups and performed one of the following protocols: (1) control group - remained in rest; (2) group with tension - application of KT with tension in the VMO region; (3) group without tension - application of KT without tension, in the same region. All volunteers were submitted to the evaluation of pain intensity, electromyography activity of the VMO and the VL and the dynamometric parameters in three different moments: before the application of KT, after the application and 72 hours after the application. Statistical analysis was performed using SPSS (version 20.0). A mixed model ANOVA was used to verify intra and intergroup differences, with a significance level of 5% (p ? 0.05). Results: There was a significant intergroup difference in pain intensity in the 72h evaluation between the no tension group and the control group. Dynamometric variables, peak torque normalized by body weight, mean peak torque, mean power and total work did not show significant difference between the groups evaluated. No differences were observed in the electromyography variables, VMO/ VL ratio and time of onset of VMO activation in relation to VL. Conclusion: Kinesio Taping, applied to the vastus medialis obliquus, does not promote immediate or late changes in the isokinetic performance and in the electromyography parameters of patients with Patellofemoral Pain Syndrome. However, was observed a reduction in pain, in the no tension group after 72 hours of application.
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Analýza dopadů větrné energie na hospodaření ČEPSu a dopad rozvojových investic firmy ČEPS na českou ekonomiku / Analysis of the impact of electricity generation from wind on investment activities of CEPS’s company, assessment of the impact of these investments on the Czech economyKrchová, Eva January 2014 (has links)
The aim of master thesis is to analyze the impact of electricity generation from wind on investment activities of CEPS's company, and also to assess the impact of these investments on the Czech economy. The work familiarizes readers with reasons for the development of the transmission system in the Czech Republic, with the concept of blackout and also with apparatus of assessing the impact of investment on the economy of the selected state -- input-output model analysis. The method used to obtain data for this work is based on the literature review, as well as expert advice on the input-output model, consultation with the experts in CEPS and the data provided by them. The theoretical part deals with Czech transmission system, and it is followed by the development of wind energy construction and the problems associated with it, with blackout and readiness of the Czech Republic to the possible failure in electricity supply. In the practical part, there are measures that are built in order to prevent the risk of blackouts in the Czech Republic, there is a more detailed examination of the Plan of development and rehabilitation of Czech transmission system, and there is also described the process of construction of analytical input-output apparatus for analyzing the impact of CEPS's development investments on the Czech economy, approximated by GDP.
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CLINICAL AND ANIMAL STUDIES OF LIPID-DERIVED PROTEIN MODIFICATIONS IN AUTISM, KIDNEY DIALYSIS, KERATITIS AND AGE-RELATED MACULAR DEGENERATIONLu, Liang 06 June 2007 (has links)
No description available.
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Efeitos da eletroestimula??o sobre os par?metros eletromiogr?ficos e dinamom?tricos do m?sculo quadr?ceps femoralFarias, Rafaela Soares de 03 November 2010 (has links)
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Previous issue date: 2010-11-03 / To analyze the effects of electrical stimulation at two frequencies on the EMG parameters (EMG) and dynamometer, in muscles with different typing. MATERIALS AND METHODS: This is a controlled clinical trial, randomized and double blind. Sixty healthy volunteers (23.6 ? 4.2anos; 54.2 ? 7.7kg, 1.62 ? 0.009 cm) of both sexes were divided randomly into three groups: control group (CG), experimental group 1 (SG1) with application of the current Russian 30 HZ and experimental group 2 (EG2) at 70 Hz The volunteers performed an initial assessment (AV1) on the isokinetic dynamometer with three repetitions maximum voluntary isometric (MVC) for knee extension concomitant uptake of EMG for the VM muscle, VL and RF. Later, after application of NMES, they underwent an experimental protocol of isometric fatigue using 70% of MVIC, ending with the completion of a final assessment (AV2) in the same manner as the AV1. RESULTS: By analyzing the profile of the 60 subjects in three broad, VM showed a higher value of RMS behavior when the VL and RF (p = 0.03 and p = 0.02). With respect to Fmed the RF muscle (p = 0.001) showed a higher value for the VM. The VM muscle showed significant increases of Fmed (p = 0.05) after electrical stimulation at 70 Hz when compared the AV1 AV2 and RF showed significant decreases (p = 0.009) after stimulation at 30 Hz during the fatigue showed an increase RMS in the VM and VL, with a reduction in RF. For the variable Fmed was observed in three broad decline during fatigue. CONCLUSION: Our findings provide evidence that the muscles VM, VL and RF fiber typing are different besides indicating that the frequency of NMES tend to relate to the muscle stimulated. Finally suggests the surface EMG as a noninvasive method for characterizing muscle / OBJETIVO: Analisar os efeitos da eletroestimula??o sobre os par?metros eletromiogr?ficos e dinamom?tricos do m?sculo quadr?ceps. MATERIAIS E M?TODOS: Trata-se de um ensaio cl?nico controlado, randomizado e duplo cego. Sessenta volunt?rios saud?veis (23.6?4.2anos; 54.2?7.7Kg; 1,62?0,009cm) de ambos os sexos foram divididos aleatoriamente em tr?s grupos: grupo controle (GC), grupo experimental 1 (GE1) com aplica??o de corrente russa a 30 HZ e grupo experimental 2 (GE2) a 70 Hz. Os volunt?rios realizaram uma avalia??o inicial (AV1) no dinam?metro isocin?tico com 3 repeti??es isom?tricas volunt?rias m?ximas (CIVM), para extens?o do joelho concomitante a capta??o da EMG para os m?sculos vasto medial (VM), vasto lateral (VL) e reto femoral (RF). Posteriormente, ap?s aplica??o da eletroestimula??o neuromusuclar (EENM) foram submetidos a um protocolo experimental de fadiga isom?trica utilizando 70% da CIVM, finalizando com a realiza??o de uma avalia??o final (AV2), nos mesmos moldes da AV1. A an?lise dos dados se deu atrav?s da utiliza??o do programa estat?stico SPSS for Windows (Statistical Packege For the Social Sciense) 17.0 e foram utilizados Anova one way nas compara??es entre os grupos e teste t pareado nas compara??es dentro dos grupos. RESULTADOS: Ao analisar o perfil dos 3 vastos nos 60 sujeitos, o VM apresentou um maior valor de RMS quando comportamento ao VL e RF (p=0,03 e p=0,02). Com rela??o a Fmed, o m?sculo RF (p=0,001) apresentou maior valor comparado ao VM. O m?sculo VM apresentou aumentos significativos da Fmed (p=0,05) ap?s eletroestimula??o a 70 Hz quando a AV1 foi comparada a AV2 e o RF apresentou quedas significativas (p=0,009) ap?s estimula??o a 30 Hz. Durante a fadiga observou-se aumento do RMS no VM e VL, com redu??o no RF. Para a vari?vel Fmed observou-se queda nos tr?s vastos durante a fadiga. CONCLUS?O: Os achados deste estudo sugerem que os m?sculos VM, VL e RF possuem tipagens de fibras diferentes al?m de indicar que as frequ?ncias de EENM tendem a se relacionar com o m?sculo estimulado. Por fim sugere a EMG de superf?cie como um m?todo n?o invasivo para caracteriza??o muscular
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O efeito inimigo ?ntimo ? aplic?vel a Dinoponera quadr?ceps (Hymenoptera, Formicidae)?Moreno, Isabelli de Carvalho 28 May 2010 (has links)
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Previous issue date: 2010-05-28 / Conselho Nacional de Desenvolvimento Cient?fico e Tecnol?gico / Food access, territory or reproductive partner can generate conflicts between individuals in many species with occurrence of aggressive behaviors. However some species respond less aggressively to intrusion by neighbors than non-neighbors in its territory to minimize the costs of continuous fight. This difference in aggression is called Dear Enemy Effect described in various vertebrates and invertebrates. To investigate if this phenomenon occurs in Dinoponera quadriceps (Hymenopetra, Formicidae) three colonies, two neighbors and one non-neighbor, were captured in its natural environment then transfered to the laboratory where we did experimental confrontation intra and inter colonies involving one pair of workers. We compared the behavioral frequency exhibited by each worker, the intensity and duration of the confrontation between a neighbor and a non-neighbor referring the place where they were collected. Our results revealed that Dear Enemy Effect does not apply to D. quadriceps due aggressive
response is more intense and longest toward neighbor than non-neighbor, probably due intra specific competition, ecological factors and characteristic of the species / O acesso a fonte de alimentos, territ?rio ou parceiros reprodutivos pode gerar conflitos de interesses entre indiv?duos em v?rias esp?cies de animais. Entretanto, v?rios animais
respondem menos agressivamente ? entrada de seus vizinhos do que a entrada de n?ovizinhos em seus territ?rios, como forma de minimizar os custos de uma agress?o cont?nua. Essa diferen?a na resposta agressiva ? conhecida por Efeito Inimigo ?ntimo, descrito em v?rias esp?cies de vertebrados e invertebrados. Para investigar se este fen?meno ocorre em Dinoponera quadriceps (Hymenoptera, Formicidae), tr?s col?nias,
sendo duas vizinhas e uma distante, foram coletadas em seu ambiente natural e transferidas para o laborat?rio onde foram conduzidos confrontos experimentais intra e entre col?nias, envolvendo um par de oper?rias. Comparamos a frequ?ncia
comportamental exibida por cada oper?ria envolvida nos confrontos, assim como a intensidade e a dura??o dos confrontos entre col?nias vizinhas e distantes com refer?ncia do local de coleta. Nossos resultados revelam que o Efeito Inimigo ?ntimo n?o ? aplic?vel ? D. quadriceps, pois resposta agressiva ? mais intensa e duradoura entre oper?rias vizinhas do que entre distantes, provavelmente devido ? competi??o intraespec?fica, fatores ecol?gicos e caracter?sticas da esp?cie.
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