Dans un article publié en 2003, M.Gromov propose une reformulation de la théorie des petites simplifications en géométrie des groupes. Dans cette version, un graphe fini définit une présentation finie de groupe; les générateurs du groupe sont les étiquettes du graphe; les relateurs sont les mots associés aux cycles; les morceaux, mots "courts " qui permettent les petites simplifications dans un groupe, sont des mots qui étiquettent deux chemins distincts du graphe. Cette thèse prend pour point de départ une brève description de cette théorie publiée par Y. Ollivier en 2006. Le concept de groupe de présentation finie à "petites simplifications", développé par R. Lyndon, M. Greendlinger et autres dans les années 60 et 70, est précurseur des groupes hyperboliques de M.Gromov à la fin des années 80, pour lesquels les propriétés combinatoires de la présentation entraînent des propriétés algébriques du groupe. Dans notre travail, nous fondons de manière rigoureuse la théorie des petites simplifications du point de vue des graphes, et développons le concept de base de "mégatuiles", utilisé implicitement par Y. Ollivier dans son article. Nous étendons ses résultats aux cas non-hyperboliques et non-métriques (par exemple$C(4)-T(4)$). Ce point de vue permet une nouvelle preuve, plus naturelle, de la résolubilité des problèmes du mot et de conjugaison pour les présentations des groupes des entrelacs alternés premiers. Nous prolongeons également les résultats d'un théorème de M. Greendlinger au cas non-métrique, répondant ainsi à une question d'I. Kapovich. / In a paper published in 2003, M.Gromov proposes a rewording of the small cancellation theory in geometric group theory. In this version, a finite graph defines a finitely presented group; generators of the group are the labels of the graph; relators are the words associated with cycles; pieces, "short" words which allow small cancellations in a group, are words which label two distinct paths in the graph.Our thesis relies on a brief description of this theory published in2006 by Y.Ollivier. The concept of finitely presented "small cancellation" group, developed by R.Lyndon, M.Greendlinger and others in the 60's and 70's, is a precursor of Gromovword-hyperbolic groups in the late of the 80's, for which combinatorial properties of the presentation imply algebraic properties of the group. In our work, we build a rigorous small cancellation theory in terms of graphs, and develop the basic concept of "megatiles", implicitly used by Y. Ollivier in his article. We extend his results to non-hyperbolic and non-metric cases (eg. $C(4)-T(4)$). This point of view allows a new proof, more natural, of thesolvability of word and conjugacy problems for presentations of prime alternating link groups. We also extend the results of a M.Greendlinger theorem to thenon-metric case, in response to a question of I. Kapovich.

The public procurement draws a lot of attention in terms of treatment with public resources. Unfortunately this attention has mostly negative character. The aim of this Diploma Thesis is to bring an untraditional overview on the processing of public procurement and introduce one of the modern ways of using auction mechanisms. Combinatorial auctions can, as it already happened in other areas, open new possibilities for contracting authorities and bidders who participate in procurement conducted in accordance with Czech legislation. Also this Diploma Thesis can be the inspiration for thought if the current rules for public procurement are in accordance with the best interests of contracting authorities and bidders. In order to present the application of combinatorial auctions on public procurement the mathematical model based on partially real data was compiled in software Lingo. The results of such model were used as the source for the effectiveness analysis of discussed topic.

Orientador: Rafael Santos Mendes / Tese (doutorado) - Universidade Estadual de Campinas, Faculdade de Engenharia Eletrica e de Computação / Made available in DSpace on 2018-08-07T23:46:24Z (GMT). No. of bitstreams: 1 Portugal_DeniseSoderoVinhas_D.pdf: 1731980 bytes, checksum: 98f3bdce8b6d0d6e00e2c6c96ba968f7 (MD5) Previous issue date: 2006 / Resumo: Uma metodologia para obter um escalonamento cíclico em Sistemas a Eventos Discretos é proposta neste trabalho. Esta metodologia parte de uma rede de Petri que modela minimamente um sistema a eventos discretos funcionando em regime periódico. O método identifica quais são as redes que podem ser tratadas por ele. As redes de Petri tratáveis serão decompostas em subredes identificadas por processos, que são classificados de acordo com suas topologias, o que permite a modelagemdo escalonamento cíclico do sistema através de uma modelagem em programação linear inteira mista. Este modelo em MILP será implementado no software GAMS. Alguns exemplos tirados da literatura serão usados para mostrar e testar a aplicação desta metodologia / Abstract: A methodology to obtain a cyclic scheduling in Discrete Events Systems is proposed in this work. This methodology initializes with a Petri netmodeling a discrete events system functioning with periodic processing. The method identifieswhich are the nets that can be treaties by him. The ¿tractable¿ Petri nets will be decomposed in subnets identified by process, which are classified according to its topologies, that permits us tomodel the cyclic scheduling of the systemby amixed integer linear programming model. This model in MILP will be implemented using software GAMS. Some examples from the literature will be used to show and to test the application of this methodology / Doutorado / Automação Industrial / Doutor em Engenharia Elétrica

Orientador: José Plínio de Oliveira Santos / Dissertação (mestrado) - Universidade Estadual de Campinas, Instituto de Matemática Estatística e Computação Científica / Made available in DSpace on 2018-08-27T11:40:03Z (GMT). No. of bitstreams: 1 Nascimento_MarcusViniciusSilva_M.pdf: 918557 bytes, checksum: de0f1627892732c764e7f5046966336f (MD5) Previous issue date: 2015 / Resumo: Nosso objetivo, nesse trabalho, é o de fazer um estudo sobre o método do crivo. A motivação reside no desejo de aplicar essas ideias a uma situação particular. Dividimos nosso trabalho em três partes. Na primeira fornecemos apenas as definições e con- ceitos básicos. Na segunda apresentamos o principio da inclusão-exclusão que embora sendo algo bastante conhecido merece destaque especial dada a sua importância como ferramenta no nosso trabalho. Na terceira e última parte, fazemos uma contextualização histórica e uma descrição da evolução das ideias do crivo de Eratóstenes-Legendre. A escolha desse crivo, dentre tantos outros, foi feita tendo em vista dois pontos. O primeiro é que o crivo de Eratóstenes-Legendre é o mais simples dentre os crivos estudados na teoria dos crivos. O segundo ponto está relacionado com o fato deste crivo fornecer a ideia geral dos crivos combinatoriais, uma vez que os crivos mais sofisticados são extensões de suas ideias básicas / Abstract: Our aim in this work is to make a study about the sieve method. The motivation lies in the intent of applying this idea in a particular situation. We splitted the study into three parts. The first part deals with definitions and basic concepts. In the second we present the principle of inclusion-exclusion while being something well known deserves special mention given its importance as a tool in our work. In the third and final part, we make a historical contextualization and a description of the evolution of the sieve Eratosthenes- Legendre ideas. The choice of sieve, among many others, has been made taking into account two points. The first is that the Eratosthenes-Legendre sieve is the simplest among the sieves studied the theory of sieves. The second point is related to the fact that this sieve provide the general idea of combinatorial sieve, since the more sophisticated sieves are extensions of its basic idea / Mestrado / Matematica Aplicada / Mestre em Matemática Aplicada

O problema de corte consiste no corte de objetos maiores para produção de peças menores, de modo que uma certa função objetivo seja otimizada, por exemplo, a perda seja minimizada. O problema de empacotamento pode também ser visto como um problema de corte, onde as peças menores são arranjadas dentro dos objetos. Uma abordagem em grafo E/OU para a resolução de problemas de corte e empacotamento foi proposta inicialmente por Morabito (1989) para problemas de corte bidimensionais e, mais tarde, estendida para problemas tridimensionais (Morabito, 1992). Nesta abordagem foi utilizada uma técnica de busca híbrida, onde se combinou a busca em profundidade primeiro com limite de profundidade e a busca hill-climbing, utilizando-se heurísticas baseadas nos limitantes superiores e inferiores. Experiências computacionais mostraram a viabilidade de uso na prática desta abordagem. Mais tarde, Arenales (1993) generalizou esta a abordagem em grafo E/OU mostrando como diferentes problemas de corte poderiam ser resolvidos, independentemente da dimensão, formas dos objetos e itens, baseado em simples hipóteses, sem realizar, entretanto, estudos computacionais. O presente trabalho tem por objetivo estender a abordagem em grafo E/OU para tratar outros casos não analisados pelos trabalhos anteriores, tais como situações envolvendo diferentes processos de corte, bem como a implementação computacional de métodos baseados na abordagem em grafo E/OU, mostrando, assim, a versatilidade da abordagem para tratar diversas situações práticas de problemas de corte e sua viabilidade computacional. / The cutting problem consists of cutting larger objects in order to produce smaller pieces, in such a way as to optimizing a given objective function, for example, minimizing the waste. The packing problem can also be seen as a cutting problem, where the position that each smaller piece is arranged inside of the objects can be seen as the place it was cut from. An AND/OR-graph approach to solve cutting and packing problems was initially proposed by Morabito (1989) for two-dimensional cutting problem and, later, extended to threedimensional problems (Morabito, 1992). That approach uses a hybrid search, which combines depth-first search under depth bound and hill-climbing strategy. Heuristics were devised based on upper and lower bounds. Computational experiences demonstrated its practical feasibility. The AND/OR-graph approach was later generalized by Arenales (1993) based on simple hypothesis. He showed that different cutting problems Gould be solved using the AND/ORgraph approach, independently of the dimension and shapes. The main objective of this thesis is the practical extension of the AND/OR-graph approach to handle other cases not considered by previous works. It was considered different cutting processes, as well as the analysis of computational implementation, showing how can it be adapted to many classes of practical cutting and packing problems.

Nesta dissertação estudamos --- do ponto de vista algorítmico --- o seguinte problema, conhecido como problema da partição conexa balanceada. Dado um grafo conexo G com pesos atribuídos a seus vértices, e um inteiro q >= 2, encontrar uma partição dos vértices de G em q classes, de forma que cada classe da partição induza um grafo conexo e que, ao considerar as somas dos pesos dos vértices de cada classe, a menor das somas seja o maior possível. Em outras palavras, o objetivo é encontrar q classes cujos pesos sejam tão balanceados quanto possível. Sabe-se que este problema é NP-difícil. Mencionamos alguns resultados sobre complexidade computacional e algoritmos que são conhecidos para este problema. Apresentamos algumas heurísticas que desenvolvemos, todas elas baseadas no uso do algoritmo polinomial para árvores, devido a Perl e Schach, que apresentamos com detalhe. Implementamos quatro heurísticas e um algoritmo de 3/4-aproximação conhecido para o caso q=2. Exibimos os resultados obtidos com os vários testes computacionais conduzidos com instâncias aleatórias, com grafos de diferentes pesos e densidades. Os resultados computacionais indicam que o desempenho dessas heurísticas --- todas elas polinomiais --- é bem satisfatório. No caso especial em que q=2, observamos que a heurística mais onerosa sistematicamente produziu soluções melhores ou iguais às do algoritmo de aproximação / In this dissertation we study algorithmic aspects of the following problem, known as the balanced connected partition. Given a connected graph G with weights defined on its vertices, and an integer q >= 2, find a partition of the vertices of G into q classes such that each class induces a connected graph, and furthermore, when we consider the sum of the weights of the vertices in each class, the smallest sum is as large as possible. In other words, the q classes must have weights that are as balanced as possible. This problem is known to be NP-hard. We mention some computational complexity and algorithmic results that are known for this problem. We present some heuristics that we designed, all of them based on the use of the polynomial algorithm for trees, due to Perl and Schach, which we show in detail. We implemented four heuristics and a 3/4-approximation algorithm that is known for q=2. We run tests on many random instances, of graphs with different weights and densities. The computational results indicate that the performance of these heuristics --- all of polynomial time complexity --- are very satisfactory. For q=2, we observed that the most expensive heuristic produced solutions with values which are systematically better or equal to those produced by the approximation algorithm.

A capacidade das células para responder corretamente a sinais externos e perceber mudanças no seu microambiente é a base do desenvolvimento, reparação de tecidos e de imunidade, bem como a homeostase do tecido normal. Transdução de sinal é o principal meio pelo qual as células respondem a sinais externos de seu ambiente e coordenam alterações celulares complexas. O estudo das vias de sinalização molecular permite-nos tentar compreender o funcionamento dessas transduções de sinais e, consequentemente, as respostas celulares a estímulos externos. Uma abordagem adequada para tais estudos é o uso de modelos matemáticos para simular a cinética das reações químicas que descrevem uma dada via de sinalização, o que nos permite gerar predições testáveis de processos celulares. Construir modelos cinéticos preditivos de vias de sinalização molecular através de dados de alto rendimento produzidos utilizando técnicas ômicas (i.e., genômica, transcriptômica, (fosfo-)proteômica) constitui um dos atuais desafios enfrentados pelos pesquisadores na área de Biologia Molecular. Recentemente, para lidar com este desafio, o arcabouço de e-Science SigNetSim foi introduzido pelo Grupo de Biologia Computacional e de Bioinformática do Instituto Butantan. Esse arcabouço permite fazer a descrição de vias de sinalização molecular através da descrição da estrutura de um modelo através de um conjunto de reações químicas, que por sua vez é mapeado para um sistema de Equações Diferencias Ordinárias (EDOs), numericamente simuladas e avaliadas. Todavia, modificações na estrutura das vias precisam ser feitas manualmente, o qual restringe severamente o número de estruturas da via que precisam ser testadas, especialmente no caso de modelos grandes. Portanto, diante desse panorama, este trabalho propõe o desenvolvimento de um método para modificar vias de sinalização molecular. Esse método se baseia no uso de bancos de dados de interatomas para fornecer um conjunto de espécies químicas candidatas para serem incluídas na via de sinalização. Um componente integrado ao arcabouço SigNetSim capaz de testar diferentes hipóteses de modificação de vias foi desenvolvido neste projeto utilizando a metodologia de heurística incremental. Para avaliar a eficiência do componente implementado, utilizamos como estudo de caso um modelo de vias sinalização de MAPKs e PI3K/Akt para realizar testes experimentais e analisar os resultados obtidos. / The ability of cells to respond correctly external signals and to perceive changes in their microenvironment is the basis for development, tissue repair and immunity as well as normal tissue homeostasis. Signal transduction is the primary means by which cells respond to external signals from their environment and coordinate complex cellular changes. The study of molecular signaling pathways allows us to understand the operation of each process of cellular signal transduction. The use of mathematical models to simulate the kinetics of chemical reactions that describe a given signaling pathway, allow us to generate testable predictions of the cell processos. To Build Kinetic predictive models to molecular signaling pathways through massive data omics produced using modern techniques, Genomics, transcriptomics, (Phospho) proteomics, is one of the current challenges faced by researchers in the field of molecular biology. Recently, the \\textit SigNetSim e-Science was introduced by the Biological Computacional and Bioinformatical Group from the Butantan Institute to face this challenge. This \\textit makes the description of molecular signaling pathways through a set of chemical reactions, which are mapped into a system of ordinary differential equations, this system will be numerically simulated and evaluated . However, changes in the structure of the pathways need to be updated manually presented in this work, which severely restricts the number of track structures that need to be tested, especially for the large models. Therefore, given this background, we present the method to modify the molecular signaling pathways. This method relies on the use of interactome database to provide a set of chemical species candidates to be included in the signaling pathway. An component integrated to SigNetSim framework able to test different hypotheses of pathways modification was developed in this project using the incremental heuristic methodology. To evaluate the implemented component, we used the MAPKs and PI3K/Akt pathways model as case study, in order to perform experimental tests and to analyze the obtained results.

Dans la collaboration entre transporteurs, plusieurs transporteurs forment une alliance pour échanger leurs demandes de transport dans le but d'améliorer la rentabilité. Dans cette thèse, nous avons étudié la planification collaborative de transport entre transporteurs de charges partielles. Plus concrètement, nous avons étudié trois sous-problèmes soulevés dans cette planification collaborative: le problème de ramassage et de livraison avec fenêtres de temps, profits et demandes réservées, le problème de détermination de gagnants dans l'échange combinatoire, et le problème de génération d'enchère.Ces trois sous-problèmes sont les problèmes clés pour la planification collaborative de transport parmi des transporteurs, et ils sont peu étudiés dans la littérature. Nous avons établi les nouveaux modèles de programmation mathématique pour ces problèmes et développé des heuristiques efficaces pour trouver des solutions très proches de leurs optimums dans un temps de calcul raisonnable. Les heuristiques proposées sont plus performantes que les solveurs commerciaux (GUROBI, CPLEX) non seulement en termes de la qualité de solution, mais aussi en termes du temps de calcul. / In carrier collaboration, multiple carriers form an alliance to exchange their delivery requests for the purpose of improving profitability. In this thesis, we have studied the collaborative transportation planning (CTP) among less-than-truckload (LTL) carriers. More concretely, we have studied three sub-problems raised in this collaborative planning: the pickup and delivery problem with time windows, profits, and reserved requests (PDPTWPR), the winner determination problem (WDP) in carrier collaboration via combinatorial exchange (CE), and the bid generation problem (BGP).These sub-problems are the key issues for collaborative transportation planning among carriers, and they are rarely studied in the literature. We have established new mathematical programming models for these problems and developed efficient heuristics to find solutions close to their optimums in a reasonable computational time. The heuristics proposed are more efficient than commercial solvers (GUROBI, CPLEX) not only in terms of solution quality, but also in terms of computation time.

Le domaine des protocoles tolérants aux pannes étudie quelles tâches concurrentes sont résolubles dans différents modèles de calcul avec pannes. Des outils mathématiques basés sur la topologie combinatoire ont été développés depuis les années 1990 pour aborder ces questions. Dans ce cadre, la tâche que l’on veut résoudre, et le protocole auquel on fait appel, sont modélisés par des complexes simpliciaux chromatiques. On définit qu’un protocole résout une tâche lorsqu’il existe une certaine application simpliciale entre ces complexes.Dans cette thèse, on étudie ces méthodes géométriques du point de vue de la sémantique. Le premier objectif est de fonder cette définition abstraite de résolution d’une tâche sur une autre plus concrète, basée sur des entrelacements de traces d’exécution. On examine diverses notions de spécifications pour les objets concurrents, afin de définir un cadre général pour la résolution de tâches par des objets partagés. On montre ensuite comment extraire de ce cadre la définition topologique de résolubilité de tâches.Dans la deuxième partie de la thèse, on prouve que les complexes simpliciaux chromatiques peuvent être utilisés pour évaluer des formules de logique épistémique. Cela permet d’interpréter les preuves topologiques d’impossibilité en fonction de la quantité de connaissances à acquérir pour résoudre une tâche.Enfin, on présente quelques liens préliminaires avec la sémantique dirigée pour les programmes concurrents. On montre comment la subdivision chromatique d’un simplexe peut être retrouvée en considérant des notions combinatoires de chemins dirigés. / The field of fault-tolerant protocols studies which concurrent tasks are solvable in various computational models where processes may crash. To answer these questions, powerful mathematical tools based on combinatorial topology have been developed since the 1990’s. In this approach, the task that we want to solve, and the protocol that we use to solve it, are both modeled using chromatic simplicial complexes. By definition, a protocol solves a task when there exists a particular simplicial map between those complexes.In this thesis we study these geometric methods from the point of view of semantics. Our first goal is to ground this abstract definition of task solvability on a more concrete one, based on interleavings of execution traces. We investigate various notions of specification for concurrent objects, in order to define a general setting for solving concurrent tasks using shared objects. We then show how the topological definition of task solvability can be derived from it.In the second part of the thesis, we show that chromatic simplicial complexes can actually be used to interpret epistemic logic formulas. This allows us to understand the topological proofs of task unsolvability in terms of the amount of knowledge that the processes should acquire in order to solve a task.Finally, we present a few preliminary links with the directed space semantics for concurrent programs. We show how chromatic subdivisions of a simplex can be recovered by considering combinatorial notions of directed paths.

京都大学 / 0048 / 新制・課程博士 / 博士(情報学) / 甲第22588号 / 情博第725号 / 新制||情||124(附属図書館) / 京都大学大学院情報学研究科通信情報システム専攻 / (主査)教授 湊 真一, 教授 五十嵐 淳, 教授 山本 章博 / 学位規則第4条第1項該当 / Doctor of Informatics / Kyoto University / DFAM