This paper reports on the study of the strategy use of Chinese English majors in vocabulary learning; the individual differences between effective and less effective learners in employing vocabulary learning strategies and the relationship between their strategies and their outcome in English learning. In this research, 118 junior English majors inChineseUniversitywere investigated. The participants were asked to take a vocabulary test and complete a vocabulary-learning questionnaire.   The data collected was analyzed using the SPSS (the Statistical Package for Social Science) and the result indicates that there are significant differences between effective and less effective learners. Effective learners use strategies more frequently and flexibly, while less effective learners turn out to be rote learners. They employ repetition strategy more often and they rely more on their mother tongue, Chinese, in vocabulary learning. Thus the translation strategy was extensively used among them. The result also shows that seven strategies, namely applied, categorization, self-monitoring, cooperation, media, elaboration and dictionary strategy are positively correlated with the vocabulary test scores and the Test for English Majors (Grade 4) scores. The above findings have certain implication for both learners and teachers.

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior / Corn is one of the crops that produce more in the world; it has a wise geographic distribution. It happens because of the big genetic variability present, including in creole cultivates which they are normally produced in small properties. The main goals of this study were to evaluate the growing and the relation between the seeds labile, grown plants and of the Amarelão creole cultivates, Lombo Baio and Oito carreiras as well as the maternal half-brothers progenies from these cultivates. The experiment happened in Santa Maria, RS in the agricultural year of 2012/2013, in block delineations aimlessly with four repetitions and portions constituted by two lines of five meters to the creole cultivates and a lattice delineation with constituted portions one line of five meters with a space of 0,2m and between lines of 0,9m. For an analysis of the growing plants was accomplished five evaluations of the plant height and leaves numbers by plant and the growing curves were adjusted by logistic model because of the thermal sum accumulated. To analyze the canonical correlation were evaluated: mass, length, width, and seeds thickness; plant height, ear insertion height, thatch diameter and leaves number by plant for grown plants, grain weights, row numbers and grain numbers by rows to the production. The logistic model was adequate to the growing curve adjusts to progenies of maternal half-brothers and corn creole cultivates. Amarelão creole cultivates, Lombo baio and Oito carreiras present the highest plant and the biggest number of leaves by plant in comparison to concerning progenies of maternal half-brothers. The most important canonical correlations were gotten between labile groups of the grown plant and production. The labile plant height and thatch diameter were the most favorable the grain production. / O milho é uma das culturas mais produzidas no mundo, com ampla distribuição geográfica. Isso se deve a grande variabilidade genética presente, inclusive em cultivares crioulas, normalmente produzidas em pequenas propriedades. Os objetivos do estudo foram avaliar o crescimento e a relação entre variáveis de sementes, plantas adultas e de produção das cultivares: crioulas Amarelão, Lombo Baio e Oito Carreiras, bem como, de progênies de meios-irmãos maternos destas cultivares. O experimento foi conduzido em Santa Maria, RS, no ano agrícola 2012/2013, em delineamento blocos ao acaso com quatro repetições e parcelas constituídas por duas fileiras de cinco metros e espaçamento entre plantas de 0,2 m e entre fileiras de 0,9 m para as cultivares crioulas e, delineamento em látice com parcelas constituídas de uma fileira de cinco metros e espaçamento entre plantas de 0,2 m e entre fileiras de 0,9 m para as progênies. Para análise de crescimento das plantas, foram realizadas cinco avaliações de altura de planta e número de folhas por planta, com as curvas de crescimento sendo ajustadas pelo modelo logístico em função da soma térmica acumulada. Para análise das correlações canônicas foram avaliadas: massa, comprimento, largura e espessura das sementes, altura de planta, altura de inserção da espiga, diâmetro do colmo e número de folhas por planta para plantas adultas e peso de grãos, número de fileiras e grãos por fileira para a produção. O modelo logístico foi adequado para o ajuste das curvas de crescimento para progênies de meios-irmãos maternos e cultivares crioulas de milho. As cultivares crioulas: Amarelão, Lombo Baio e Oito Carreiras apresentaram maior altura de plantas e maior número de folhas por planta em comparação às respectivas progênies de meios-irmãos maternos. As correlações canônicas mais importantes foram obtidas entre os grupos de variáveis de planta adulta e de produção. As variáveis altura de planta e diâmetro do colmo as que mais favorecem a produção de grãos.

Ce travail de thèse porte sur l’étude expérimentale des polaritons de microcavité dans des microstructures de semiconducteurs III-V. Il présente un volet fondamental sur les propriétés de cohérence et de polarisation des lasers à polaritons, et un volet plus applicatif dédié à la démonstration de principe de nouveaux dispositifs tout optique à polaritons.Dans la première partie, nous utilisons une caméra streak en mode « single shot » pour mesurer des corrélations de photons du second ordre avec une résolution à la picoseconde. Cette technique nous permet de mesurer la statistique d’émission de lasers à polaritons. Nous analysons ainsi la dynamique à l’échelle picoseconde de l’établissement de la cohérence spontanée et de la polarisation du mode, à l’allumage du laser. Nous mettons en évidence une initialisation stochastique de la polarisation, suivie d’une précession autour d’un champ magnétique effectif présent dans la cavité. Le rôle de la dimensionnalité de la cavité est discuté, et un modèle théorique permet une meilleure compréhension de ces mesures. La deuxième partie est dédiée à la réalisation de dispositifs à polaritons, dont le contrôle est tout optique. Ces dispositifs sont essentiellement constitués d’un résonateur 0D couplés à des guides 1D d’entrée et de sortie. Nous démontrons le fonctionnement d’un « router » à polaritons, et observons une bistabilité optique du résonateur 0D pilotée à distance. Ce dernier effet est l’ingrédient de base d’une mémoire optique, et nous montrons des résultats préliminaires concernant l’implémentation de portes logiques tout optiques AND, OR et XOR. / This PhD thesis is dedicated to the experimental study of microcavity polaritons in III-V semiconductor microstructures. It consists in a fundamental part focusing on the coherence and polarization properties of polariton lasers, and in a more applied second part which concerns the proof of principle of new all-optical polariton devices.In the first part, we use a streak camera in the single shot regime to measure second order photon correlations with a picosecond resolution. This technique allows measuring the emission statistics of polariton lasers and analyzing at the picosecond scale the dynamics of the establishment of the spontaneous coherence and polarization of the mode during the laser initialization. We show a stochastic initialization of the polarization followed by a precession around an effective magnetic field inside the cavity. The influence of the system dimension is discussed and a theoretical model allows us to better understand these measurements. The second part is dedicated to the realization of polariton devices with an all-optical control. These devices are constituted of a 0D resonator coupled to 1D input and output waveguides. We demonstrate the operation of a polariton router and a remotely controlled optical bistability. This last effect is the core ingredient of an optical memory and we show preliminary results on the implementation of all-optical AND, OR and XOR logic gates.

Les théories de champ moyen quantique représentent une base robuste pour la description de la dynamique de nombreux systèmes physiques, des noyaux aux systèmes moléculaires et aux agrégats. Cependant, le traitement incomplet des corrélations électroniques au niveau du champ moyen empêche de donner une description propre de la dynamique, en particulier la dynamique dans les régimes dissipatifs. La dissipation est intrinsèquement liée à la thermalisation qui représente le phénomène cible à d'écrire dans ce travail. Nous avons exploré un schéma purement quantique en terme des matrices densités et qui consiste en l'inclusion des corrélations de type collisions, responsables de la thermalisation dans les systèmes quantiques finis. Ceci est fait en traitant les corrélations entre deux particules avec la théorie des perturbations dépendantes du temps tout au long d'un intervalle de temps. Ceci permet de créer un ensemble d'états de type champ moyen pur pour les différentes configurations. Ces états sont traités stochastiquement dans la dynamique et fournissent en moyenne un état corrélé. Nous proposons dans ce travail une reformulation de cette théorie en terme des fonctions d'ondes où les corrélations sont traitées comme des transitions multiples de type particule-trou, limitées aux transitions deux-particules-deux-trous dans notre cas. On applique le schéma obtenu à un modèle unidimensionnel simulant de petites molécules. La capacité de cette théorie à introduire les effets dissipatifs dans le cadre du champ moyen est illustrée à travers plusieurs observables tels que les matrices à un et deux corps, les nombres d'occupation et l'entropie à un corps / Quantum mean field theories represent a robust basis for the description of many dynamical situations from nuclei to molecular systems and clusters. However, the missing of electronic correlations on top of mean field prevents them to give a proper description of the dynamics, in particular dissipative dynamics. Dissipation is intrinsically linked to thermalization which represents the target phenomenon to be described in this thesis. We thus explore a fully quantum mechanical strategy proposed in terms of density matrices in the case of nuclear collisions and which consists in the inclusion of collisional correlations responsible of thermalization in quantum finite systems. This is done by treating two body correlations in time dependent perturbation theory along a certain time span that allows to create an ensemble of pure mean field states for different configurations. These states are used into the dynamics, stochastically, providing in the average one correlated state. We propose in this work a reformulation of this theory in term of wave functions where correlations are translated into multiple particle-hole transitions, restricted to two-particles-two-holes transitions in our case. We apply the obtained scheme to a one dimensional model simulating small molecules. The ability of this theory to include dissipative effects on top of mean field is illustrated through several observables such as the one and two body density matrices, the occupation numbers and the one body entropy.

An important characteristic of influenza A is its ability to escape host immunity through antigenic drift. A novel influenza A strain that causes a pandemic confers full immunity to infected individuals, yet because of antigenic drift, these individuals have decreased immunity to drifted strains. We compute the required decrease in immunity so that a recurrence is possible. Models for influenza A must make assumptions on the host contact structure on which the disease spreads. By computing the reproduction number, we show that the classical random mixing assumption predicts an unrealistically large decrease of immunity before a recurrence is possible. We improve over the classical random mixing assumption by incorporating a contact network structure. A complication of contact networks is correlations induced by the initial pandemic. Thus, we provide a novel analytic derivation of such correlations and show that contact networks may require a dramatically smaller drop in immunity before recurrence. Hence, the key new insight is that on contact networks the establishment of a new strain is possible for much higher immunity levels of previously infected individuals than predicted by the commonly used random mixing assumption. This suggests that stable contacts like classmates, coworkers and family members are a crucial path for the spread of influenza in human population. / Graduate

No description available.

Pengar har under en lång tid spelat en central roll i människans samhälle och dagens samhälle präglas av allt mer handel. Utifrån detta har nya betalningsmetoder utvecklats. En förändring i konsumentbeteendet har bidragit till att allt fler individer väljer elektroniska betalningstjänster. En relativt ny innovation är kryptovalutan bitcoin som erbjuder betalning mellan köpare och säljare utan inblandning av en tredje part. Ett flertal studier har gjorts med syftet att fastställa om bitcoin är en valuta eller en tillgång, något som visat sig vara svårt. Något som varit tydligare är att bitcoins värdeförändringar inte tycks vara korrelerad med andra investeringsalternativ. I en studie av Brière et al. (2015) drogs slutsatsen att bitcoin är en intressant tillgång för en investerare tack vare bitcoins låga korrelationskoefficient med andra tillgångar. Denna studie grundar sig i de teoretiska utgångspunkterna om Famas (1970) hypotes om den effektiva marknaden, Markowitz (1952) moderna portföljteori och Rogers (2003) teori om spridning av innovationer. Med detta som utgångspunkt är syftet med denna studie att undersöka hur korrelationskoefficienten mellan bitcoin och traditionella investeringstillgångar som aktier, valutor och råvaror ser ut idag samt hur dessa har förändrats över tid. Med hjälp av Famas (1970) teori om effektiva marknader och Rogers (2003) teori om spridning av innovationer kommer en diskussion om huruvida bitcoins egenskaper som investering i den moderna portföljen har förändrats i takt med att bitcoin blivit mer använd, både som betalningsmedel och investeringsalternativ. För att besvara dessa frågor undersöks korrelationskoefficienterna mellan bitcoin och elva andra tillgångar i kombination med en analys av en deskriptiv statistik. Med en undersökningsperiod som sträcker sig från 18 augusti 2011 till 17 mars 2017. Denna period har även delats upp i mindre tidsperioder för att utifrån detta analysera om det skett några förändringar i korrelationen mellan bitcoin och de traditionella tillgångarna i studien. Resultatet visade att bitcoin inte är korrelerad med andra traditionella tillgångar, oavsett vilken tidsperiod som undersöks. Det visade sig att bitcoin i förhållande till andra tillgångar är en riskfylld investering på grund av bland annat en hög volatilitet. Dock kompenseras detta av bitcoins höga årlig avkastning. Av resultatet framgår det även att volatiliteten för bitcoin har minskat med tiden och att kryptovalutan inte är lika riskfylld idag jämfört med tidigare.

Conventional ‘well-stirred’ extrapolation methodology using intrinsic metabolic clearance data from rat liver microsomes poorly predicts in vivo clearance for approximately half of drug discovery compounds. The aim of this present study was to gain a more detailed understanding of the hepatobiliary disposition pathways which influence drug clearance. A set of 77 new chemical entities (NCEs), demonstrating a range of physicochemical properties and in vitro-in vivo clearance correlations (IVIVC), were employed to explore relationships between hepatobiliary disposition pathways in rat and physicochemical, structural and molecular properties of the NCEs. Primary rat hepatocytes with >80% cell viability were successfully isolated from male Han Wistar rats and used to establish in vitro models of drug uptake and biliary efflux. Preliminary studies with cultured primary rat hepatocytes indicated that uptake of d8-taurocholic acid and pitavastatin was time, concentration and temperature dependent. Initial studies with sandwich cultured primary rat hepatocytes demonstrated that cellular accumulation and biliary efflux of [3H]-Taurocholic acid was time and concentration dependent. These in vitro rat hepatocyte models were then used to investigate drug uptake and biliary efflux for all NCEs. In general, NCEs with high (passive) permeability showed better IVIVC and a lower incidence of active uptake and biliary efflux compared to NCEs with lower permeability, suggesting permeability is a key property influencing hepatobiliary drug disposition in rat. Preliminary in silico models analysing structural and molecular descriptors of substrates of active transport in rat hepatocytes were developed and indicated modest potential to highlight clearance pathways beyond hepatic metabolism but further follow up work with larger, more diverse compound sets is warranted to gain confidence in these models. Extended clearance models were investigated to estimate the effect of hepatic transporters on clearance and to predict the overall hepatic clearance of the NCEs. None of these models resulted in a 1 to 1 correlation but in general, improvements in clearance predictions were made when drug transport processes were accounted for. In vivo excretion studies using bile duct cannulated rats demonstrated that NCEs with high permeability and good IVIVC were not directly eliminated in bile or urine as unchanged drug, whereas NCEs with lower permeability and poor IVIVC (> 3-fold under predicted) were all directly eliminated unchanged indicating key drivers of clearance beyond metabolism. In conclusion these investigations confirmed a role for hepatic transporters in clearance but the complex nature of active transport mechanisms and a lack of robust in vitro tools create challenges in the quantitative prediction of hepatobiliary clearance. However, one of the key findings from this research, which is highly applicable in early drug discovery, was to identify the existence of disposition permeability relationships. These can be anticipated by observing physicochemical parameters of NCEs in conjunction with conventional IVIVC, since NCEs that are not highly permeable, possess some hydrophobic characteristics, and which are poor substrates of cytochrome P450 enzymes are more likely to be good substrates of transporters and be directly eliminated in bile and/or urine. The present study focused on exploring hepatobiliary disposition pathways using rat as the investigative species. Whilst there is no guarantee that pathways relevant to rat will be similar to other preclinical species or even humans, an early diagnosis of dominant clearance pathways can guide a more efficient use of the ADME-PK toolbox.

<p>Despite worldwide interest in a number of applications involving cryogenic fluids that are crucial to future space exploration, there is presently a lack of a large, reliable cryogenic pool boiling critical heat flux (CHF) database that can be used for assessment of accuracy of available predictive tools - model and correlations – or development of new tools. This shortcoming is a primary motivation for the present study, prompting compilation of a new consolidated cryogenic pool boiling CHF database from world literature. The database is used to assess accuracy of previous models and correlations, which are segregated according to ability to predict key operating parameters, such as pressure, surface orientation, and subcooling. A new correlation is constructed which shows very good predictive accuracy, evidenced by a mean absolute error of 16.95%, based on Earth gravity data which comprise a large fraction of the consolidated database. Using a limited subset of datapoints for three cryogens and a reduced gravity range of 0 to 0.7466, the new correlation is further modified with a reduced gravity multiplier to tackle reduced gravity conditions. The modified correlation has a mean absolute error of 17.47%, slightly higher than for Earth gravity alone. Overall, the new correlations are proven far more accurate than all prior models and correlations and therefore constitute new powerful tools for design of cryogenic space systems. It is shown CHF is very sensitive to pressure, increasing with increasing pressure up to maximum before decreasing appreciably toward critical pressure. CHF is also shown to be strongly influenced by surface orientation, being highest for horizontal surfaces and decreasing monotonically with increasing orientation angle, and increasing fairly linearly with increased subcooling.</p><p>Additionally, CHF models and correlations are assessed using amassed quenching CHF data that showed overpredictions of data. A new correlation is formulated which includes the effects of surface material and heater thickness to achieve high predictive accuracy for complied quenching CHF database. The new correlation has a mean absolute error and root mean square error of 10.79% and 16.12%, respectively, based on a compiled database. Analysis of complied quenching data showed that CHF is sensitive to the surface material, increasing with increasing thermal conductivity but, the influence of surface material becomes weak with increasing thermal conductivity. CHF is also strongly influenced by heater thickness, increasing with increased heater thickness till it reaches the asymptotic thickness. </p>

L'étude de l'état isolant de Mott est un des domaines très actif de la recherche en matière condensée car les fortes corrélations qui en sont à l'origine donnent naissance à des états de la matière très variés et avec des applications potentielles. Sr₂IrO₄ est un isolant de Mott exotique car induit par un fort couplage spin-orbite. Il permet d'étudier l'impact des corrélations électroniques sur les propriétés de basses énergies sous un angle nouveau. L'objet de cette thèse est l'étude expérimentale des propriétés électroniques de ces composés iridates par des mesures d'ARPES permettant des observations directes de la structure électronique dans l'espace réciproque et de RMN et μSR, qui donnent une vision locale dans l'espace réel. Nous nous sommes en particulier intéressés à la transition isolant métal pouvant survenir en dopant ce composé. Une façon originale de doper Sr₂IrO₄ que nous avons étudiée en détails est de substituer l'iridium par du rhodium. Les deux sont isovalents, mais le rhodium capture un électron conduisant à un dopage effectif en trous. Grâce à l’ARPES, nous avons mis en évidence les différentes bandes de la structure électronique. Nous avons étudié attentivement le caractère orbital de ces bandes et mis en évidence des anisotropies résiduelles en certains points de l’espace réciproque, survivant malgré la présence du fort couplage spin-orbite. Ceci, ainsi que des effets de repliement de la structure électronique, donnent lieu à des variations brutales d'intensité, qui doivent être prises en compte pour analyser correctement les spectres. Lors du dopage avec le Rh, la phase métallique obtenue reste très incohérente, avec une absence de pic de quasiparticule et un pseudogap uniforme sur l'ensemble de la surface de Fermi. Le gap de Mott ne semble pas se fermer. Le pseudogap peut révéler une brisure de symétrie mais aussi l’effet du désordre introduit par le Rh et nous discuterons son origine, en lien avec la physique d’autres systèmes corrélés. Nous montrons que pour de faibles taux de substitution Ir/Rh, l’ajout de porteurs trous contrôle le comportement du système alors qu’à des taux de substitutions plus élevés, le nombre de porteurs est stable mais le désordre augmente et contrôle à son tour la physique. Nous nous sommes aussi intéressés aux propriétés électroniques et magnétiques sondées par la RMN de l'oxygène 17 sur poudre et poudre orientée et par μSR. La RMN permet de différencier les deux sites d'oxygène de Sr₂IrO₄ nous permettant de déterminer certains paramètres nucléaires préalables à l'étude fine des propriétés électroniques. Dans le composé pur, nous avons étudié la transition magnétique et observé ce qui semble être le développement d'un moment sur l'oxygène apical. Dans les composés dopés, nous ne voyons pas de désordre structural important malgré des taux de dopage allant jusqu'à 15% de rhodium. Les propriétés magnétiques présentent néanmoins des signes d’inhomogénéité, plus marqués dans le cas du dopage lanthane. Les fluctuations dans le composé métallique montrant une prédominance des corrélations antiferromagnétiques. De son côté, la μSR a permis de construire le diagramme de phases de la transition antiferromagnétique et de mettre en évidence l'inhomogénéité de la transition magnétique dans les échantillons faiblement dopés. À basse température, nous confirmons que la phase magnétique évolue, peut-être avec l’apparition d’un moment sur l’oxygène, et cet effet est même renforcé dans les composés faiblement dopés. Au-dessus de la température de transition antiferromagnétique, nous n'avons pas trouvé de signature d'une transition vers une phase de boucles de courant observée par d'autres techniques. Cette étude permet d’attribuer à Sr₂IrO₄ dopé rhodium le caractère assez rare de matériau 2D fortement corrélé à désordre contrôlé. De manière plus générale, cet exemple devrait permettre de mieux comprendre les effets éventuels de désordre associés à d’autre façons de doper les iridates. / The study of the insulating Mott state is a very active field of research in condensed matter because of the strong correlations usually at play which can lead to a large variety of states of matter, with potential applications. Sr₂IrO₄ is an exotic Mott insulator because it is induced by a strong spin-orbit coupling. It allows studying the impact of electronic correlations on the low energy properties from a new viewpoint. The subject of this thesis is the experimental study of the electronic properties of these iridate compounds by ARPES measurements allowing direct observations of the electronic structure in reciprocal space and NMR and μSR, which give a local view in real space. We have in particular studied the metal to insulator transition which can occur in this compound upon doping. An original way to dope Sr₂IrO₄ that we have investigated in details is to substitute iridium by rhodium. Both are isovalent but the rhodium captures an electron leading to an effective hole doping. Thanks to ARPES we have identified the different bands in the electronic structure. We have studied in details the orbital character of these bands and pointed out residual anisotropies at some points in the reciprocal space, which survive despite the strong spin-orbit coupling. This, as well as the folding effects of the electronic structure, give rise to sudden variations in intensity, which must be taken into account in order to correctly analyze the spectra. Upon doping with Rh, the obtained metallic phase remains very incoherent, with no quasiparticle peak and a uniform pseudogap over the full Fermi surface. The Mott gap does not seem to be closing. The pseudogap can reveal symmetry breaking but also the effect of the disorder introduced by the Rh and we will discuss its origin, in relation to the physics of other correlated systems. We show that for low Ir/Rh substitution rates, the addition of hole carriers controls the behavior of the system while at higher substitution rates, the number of carriers is stable but the disorder increases and in turn controls physics.We were also interested in the electronic and magnetic properties probed by 17 oxygen NMR on powder and oriented powder samples and by μSR. NMR makes it possible to differentiate the two oxygen sites in Sr₂IrO₄ allowing determining some nuclear parameters necessary to the fine study of the electronic properties. In the pure compound, we have studied the magnetic transition and observed what appears to be the development of a moment on the apical oxygen. In the doped compounds, we do not see any significant structural disorder despite doping levels up to 15% rhodium. However, the magnetic properties nevertheless show signs of inhomogeneity, which are more pronounced in the case of lanthanum doping. The fluctuations in the correlated metal compound show a predominance of antiferromagnetic correlations. From our μSR investigation, we could construct the magnetic phase diagram which highlights the inhomogeneity of the magnetic transition in the low-doped samples. At low temperature, we confirm that the magnetic phase evolves, perhaps with the appearance of a moment on the oxygen, and this effect is even enhanced in the lightly doped compounds. Above the antiferromagnetic transition temperature, we did not find signatures of the current loop phase observed by other techniques. This study makes it possible to attribute to Sr₂IrO₄ doped with rhodium the rather rare character of strongly correlated 2D material with controlled disorder. More generally, this example should provide a better understanding of the potential effects of disorder associated with other ways to dope iridates.