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Developmental markers of time and associated moderatorsYao, Christie 16 July 2009 (has links)
Background: The selection of a developmental time metric is useful in understanding causal processes that underlie cognitive change, and for the identification of potential moderators of cognitive decline. We examined various conceptualizations of developmental time (e.g., chronological age, measurement occasion, time-in-study, and time-to-attrition), and moderators of cognitive decline that are associated with CNS functioning (e.g., intraindividual variability and chronic health conditions).
Methods: Participants were 304 community-dwelling Caucasian older adults (208 women and 96 men), aged 64 to 92 (M = 74.02, SD = 5.95) in a longitudinal study. HLM models were fit to examine patterns and moderators of cognitive change.
Results: Time-to-attrition was associated with significant cognitive decline. Greater intraindividual variability, a behavioural indicator of CNS deficits, was associated with impaired performance on executive functioning and episodic memory measures.
Conclusions: Our findings underscore the importance of selecting an appropriate time metric in order to address the possible causal mechanisms underlying the association between cognitive loss and selective attrition (i.e., CNS integrity).
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SOCIAL DETERMINANTS OF HEALTH AND HEALTH BELIEFS AMONG AFRICAN AMERICAN WOMEN WITH CHRONIC HEALTH CONDITIONS AND THEIR DECISIONS TO PARTICIPATE IN GENETIC RESEARCHHarmon, Carolyn Wilma 06 July 2010 (has links)
No description available.
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Research Participation Decision-Making Among Youth and Parents of Youth with Chronic Health Conditions: A DissertationPagano-Therrien, Jesica 11 April 2016 (has links)
The purpose and aims of this qualitative descriptive study were to describe how past experiences with research (including communication, information, values and support) may contribute to research fatigue among youth and parents of youth with HIV, CF, and T1D. Eighteen parents and youth were purposively recruited from outpatient subspecialty clinics at a major academic medical center. They took part in qualitative interviews, completed a demographics form, and the Decisional Conflict Scale. Youth participants also completed the Erikson Psychosocial Stage Inventory. Two major themes emerged: blurred lines and hope for the future. Research fatigue was not found in this sample. Results point to challenges with informed consent in settings where research and clinical care are integrated, and suggest that protective factors allow for continued participation without excess burden on youth and parents. Strategies to minimize research fatigue and support engagement in research are offered.
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