Conselho Nacional de Desenvolvimento CientÃfico e TecnolÃgico / A necessidade de obter uma matriz energÃtica menos poluente e em harmonia com o meio ambiente à um tÃpico muito importante no sÃculo XXI. Este trabalho apresenta um conversor cc-ca de dois estÃgios para injetar a energia de um arranjo de painÃis fotovoltaicos à rede elÃtrica. O primeiro estÃgio à um conversor elevador, isolado, baseado na CÃlula de ComutaÃÃo de TrÃs Estados (CCTE), responsÃvel por elevar a tensÃo dos painÃis fotovoltaicos de 48 Vcc para 400 Vcc e de extrair a mÃxima potÃncia disponÃvel deles. O segundo estÃgio consiste em um conversor monofÃsico cc-ca, ponte completa, responsÃvel por injetar a energia na rede elÃtrica de baixa tensÃo (220 Vca, 60 Hz). SÃo apresentados estudos teÃricos e exemplos de projeto dos circuitos de potÃncia e controle para ambos os estÃgios e, com o objetivo de validar a anÃlise, sÃo apresentados resultados de simulaÃÃo computacional, complementados com resultados experimentais, correspondentes a um protÃtipo de laboratÃrio de 850 W. O rendimento global obtido experimentalmente à aproximadamente 86,5% enquanto que a distorÃÃo harmÃnica total da corrente entregue à rede elÃtrica obtida via simulaÃÃo computacional à 3,8% a plena carga. / In the 21st century, the need of a more clean and environment friendly power matrix has become a very important issue. Therefore this work presents a two stage cc-ac converter for connecting a photovoltaic array to the electrical grid. The 1st stage itâs an isolated boost converter, based in the Three Stage Switching Cell (TSSC), in charge of boosting the photovoltaic array voltage from 48 Vcc to 400 Vcc and to track its maximum power point. The 2nd stage is a single-phase cc-ac Full-Bridge converter responsible of injecting the photovoltaic power into the low voltage power grid (220 Vac, 60 Hz). Both, theoretical analysis and designs examples of power and control circuits are presented for the two stages and, in order to validate the analysis, simulation results complemented with experimental results from an 850 W laboratory prototype are presented. The overall efficiency obtained from the prototype was 86.5% while the total harmonic distortion of the current obtained via simulation was 3.8% at full load.

INTRODUÇÃO: O limite de tempo de isquemia renal sem causar um dano permanente à função ainda é um questionamento pertinente na prática cirúrgica urológica. Algumas cirurgias requerem um campo cirúrgico menos sangrante, necessitando de uma interrupção temporária do fluxo sanguíneo para o parênquima renal através de clampeamento do pedículo. Este estudo objetivou avaliar qual técnica de clampeamento em isquemia isotérmica é superior, em termos de preservação da função renal. MÉTODOS: Neste estudo, foram utilizados 28 coelhos da raça New Zealand distribuídos em quatro grupos de forma randomizada e submetidos à laparotomia com interrupção do fluxo sanguíneo renal esquerdo, conforme grupo: grupo 1 - Controle, sem isquemia (4 animais), grupo 2 - Isquemia seletiva (8 animais), grupo 3 - Isquemia não-seletiva (8 animais) e grupo 4 - Isquemia não-seletiva intermitente (8 animais). Os animais foram submetidos à análises cintilográficas da função renal com mercaptoacetiltriglicina (MAG3) e dosagens séricas de creatinina no pré-operatório, no primeiro, terceiro e sétimo dias pós-operatórios. Após 15 dias da cirurgia, os animais foram sacrificados e os rins submetidos à análise histológica. RESULTADOS: A análise cintilográfica da função renal mostrou que os três grupos submetidos à isquemia apresentaram um agravo semelhante, nas primeiras 24 horas; não havendo diferença estatística entre eles no tocante a perda de função renal do rim esquerdo (p= 0,165), neste período. No exame do terceiro dia pós-operatório, houve diferença estatística (p= 0,006) entre os grupos não-seletivo (3) e o intermitente (4), mostrando uma superioridade do fator desclampeamento na proteção à função renal. No sétimo dia pós-operatório, o grupo do clampeamento seletivo (2) mostrou-se superior (p< 0,001) ao grupo não-seletivo (3), mas não apresentou diferença estatística em relação ao grupo intermitente (4). Este último, por sua vez, também apresentou-se superior ao grupo 3, com diferença estatística (p< 0,001). Após sete dias não foi observada diferença estatística entre os grupos 2 e 4. A histologia e a creatinina não mostraram diferença estatisticamente significante entre os grupos isquêmicos. Do ponto de vista funcional, a isquemia seletiva e a intermitente foram superiores em relação a não-seletiva. CONCLUSÃO: O modelo utilizado neste estudo mostrou uma superioridade da isquemia isotérmica seletiva e da intermitente em relação a não-seletiva na proteção da função renal. Não houve diferença entre o clampeamento seletivo e o intermitente não-seletivo na função do rim / INTRODUCTION: The time limit of renal ischemia with no permanent damage to renal function still remains as a pertinent question in urologic surgical practice. Several procedures require a bloodless surgical field most of time needing an interruption of blood flow to the renal parenchyma and they can require hilum control and clamping. This study assessed which normothermic clamping technique is superior in order to preserve kidney function. METHODS: In this project, 28 New Zealand rabbits were distributed in four groups by randomization and submitted to laparotomy and blood flow interruption of left kidney: Group 1 - Control, no ischemia (four animals), Group 2 Selective ischemia (eight animals), Group 3 Nonselective ischemia (eight animals) e Group 4 intermittent nonselective ischemia (eight animals). The animals were submitted to renal scintigraphy with mercaptoacetiltriglicin (MAG3) and serum creatinine analysis preoperatively and at days 1, 3 and 7 after left hilum clamping. The animals were submitted to nephrectomy and immediately sacrificed and the kidneys subjected to blinded evaluation by a nephropathologist. RESULTS: Renal scintigraphy showed equal damage in the three groups in first 24 hours, with no statistical difference in loss of left kidney function (p= 0,165) in this period. At third day examination, there was statistical difference (p= 0,006) between the nonselective group (3) and intermittent one (4), demonstrating a superiority of declamping factor in renal function protection. At seventh postoperative day, selective group (2) proved to be better (p< 0,001) than nonselective one (3), however there was not statistical difference between group 2 and the intermittent group (4). The intermittent clamping group was also superior to group 3 (p< 0,001). Histopathology and serum creatinine did not demonstrate statistical difference among groups. Functionally, selective and intermittent warm ischemia techniques are better than nonselective one. CONCLUSION: The model used in this study presented a superiority of selective clamping and intermittent arteriovenous clamping in shielding the renal function. No difference occurred between selective clamping and intermittent nonselective one

Vevaxeldeformation studeras i samband med uppspänning i en virvelfräsmaskin inför en skärande process. Syftet är att öka förståelse om deformationsbeteendet av vevaxelns viktiga funktionsytor genom analysering med Finita elementmetoden (FEM). Volvo Cars i Skövde hanterar i dagsläget oönskad vevaxeldeformation genom tidskrävande fysiska tester. Därför önskar företaget ta stöd av virtuell analysering. Detta arbete leder även till ett fastställande om FEM är ett tillämpbart verktyg att utgå ifrån för att upprätthålla snäva vevaxeltoleranser. Användning av virtuell analysering istället för fysiska tester skulle medföra tidsbesparing och ha positiv inverkan på miljön.  Programvaran Abaqus används för genomförande av deformationsanalyser vilka också utvärderas mot fysiska mätningar i en dragprovmaskin (Instron) för att därigenom säkerställa pålitligheten av använd FE modell.  Analyser genomförs huvudsakligen för deformationsuppkomst av vevaxeln i samband med uppspänning. Två olika typer av vevaxlar analyseras. Till respektive vevaxel skapas en FE modell med ansatta randvillkor och belastningsförhållanden utgående från en genomförd mekanisk analys av vevaxeln. Erhållna resultat visar att bricksidorna av vevaxeln deformeras med i storleksordningen <img src="http://www.diva-portal.org/cgi-bin/mimetex.cgi?10%5E%7B-2%7D" /> mm då vevaxeln belastas i samband med uppspänning med en hoptryckning på 0,2 mm. Denna deformation anses medföra risk att ett bearbetningsfel kan förorsakas. Analyserna visar även vilka ytor som deformeras mest/minst. Utvärdering mot dragprovning indikerar att riktning på vevaxeldeformation stämmer överens med analyserna, men att avvikelser på deformationsstorleken förekommer. Skillnaden kan möjligen förklaras med att E-modulen varierar inom den testade vevaxeln medan den definierade E-modulen i Abaqus antar ett konstant värde. Dessutom kan eventuella felkällor från dragprovningen ha inverkan på resultatutfallet av de fysiska mätningarna.  Genomförda analyser tyder på att FEM är tillämpbar för analysering av vevaxeldeformation och rekommendationer om en lämplig FE modell tillhandahålls. En potentiell lösning till deformationsproblemet anses vara beräkning av optimal klämkraft vid uppspänning. / Crankshaft deformation is studied in connection with clamping conditions in a whirl milling machine before a cutting process. The purpose of the project is to increase knowledge about the deformation behaviour of the crankshaft and its important functional surfaces by performing analyses using the finite element method (FEM). Volvo Cars in Skövde, Sweden is currently managing unwanted crankshaft deformation occurrence by using time consuming physical testing methods. Therefore, the company wish to use virtual analyses instead of physical tests. This work also leads to a determination if FEM is an applicable tool in order to maintain narrow tolerances of the crankshaft. Using virtual analyses instead of physical tests would be time saving and would also have a positive impact on the environment. The computer software Abaqus is used to implement the deformation analyses that are also evaluated against physical measurements done with a tensile testing machine (Instron) and thereby be able to ensure the reliability of the used FE model. FE analyses are mainly performed to evaluate the deformation of the crankshaft associated with clamping. Two different crankshaft types are being analysed. A FE model is created for each crankshaft along with applied boundary and load conditions according to performed mechanical analysis of the crankshaft. Obtained results show that the thrust bearing sides of the crank pins on the crankshaft deform in the range of <img src="http://www.diva-portal.org/cgi-bin/mimetex.cgi?10%5E%7B-2%7D" /> mm when the crankshaft is compressed during clamping with 0.2 mm. This deformation is considered to entail a risk for a processing error to occur. At the same time the analyses show which surfaces are most/least deformed. Evaluation according to the tensile testing indicates that the direction of the crankshaft deformation corresponds to the analysis but slight deviation of the deformation magnitude is present. The deviations can be explained by variations of the E-module within the crankshaft while the defined E-module in Abaqus has a constant value. Furthermore, there is a possibility that sources of error from the tensile tests can have an influence on the obtained results from the physical measurements. Conducted analyses indicates that FEM is applicable for crankshaft deformation analyses and recommendations of a suitable FE model are provided. A potential solution of the deformation problem is considered to be the calculation of optimal clamping force.

Étude expérimentale de l'hypothermie ultra-rapide par ventilation liquide totale au cours de situations critiques d'ischémie-reperfusionL’ischémie-reperfusion est une situation rencontrée de façon pluri-quotidienne en anesthésie-réanimation. Sa prise en charge thérapeutique est limitée au traitement de la pathologie causale et à la suppléance des organes défaillants. Dans ce contexte, l’hypothermie possède des effets cyto- et organo-protecteurs pléiotropes, dont les bénéfices pourraient être pénalisés par des délais d’application trop longs. La ventilation liquide totale (VLT) hypotherme est une approche émergente, permettant de refroidir très rapidement un organisme. Elle consiste à ventiler les poumons avec des perfluorocarbones liquides, permettant d’assurer les échanges gazeux, tout en faisant varier la température de ces perfluorocarbones, et en utilisant le poumon comme bio-échangeur thermique.L’objectif de cette thèse était d’investiguer les effets de la VLT hypotherme au cours de la défaillance multi-viscérale dans des modèles d’ischémie-reperfusion systémique chez le lapin.Dans un premier travail, nous avons étudié un modèle d’ischémie-reperfusion par clampage de 30 minutes de l’aorte abdominale supra-cœliaque, suivi par 5 heures de reperfusion. Les animaux témoins développaient une défaillance multi-viscérale d’expression clinico-biologique sévère. Dans le groupe soumis à la VLT, cette stratégie permettait d’abaisser la température à 33°C en moins de 15 minutes, cible thermique maintenue pendant 75 minutes avant réchauffement. Les défaillances cardio-circulatoires, rénales et hépato-splanchniques étaient atténuées de façon pérenne, avec une protection d’autant plus puissante que la VLT était initiée tôt par rapport au clampage.Dans un second travail, nous nous sommes appuyés sur un modèle d’arrêt cardiaque en rythme non choquable par asphyxie, à l’origine d’une mortalité majeure de cause neurologique, et d’un syndrome post-arrêt cardiaque sévère. La VLT hypotherme offrait une neuro- et cardio-protection puissante, et une réduction du syndrome inflammatoire. L’hyperhémie cérébrale, la production d’espèces réactives de l’oxygène et l’augmentation de la perméabilité de la barrière hémato-encéphalique étaient également significativement réduits.Ces travaux démontrent qu’une hypothermie systémique ultra-rapide par VLT hypotherme atténue les effets délétères multi-viscéraux de l’ischémie-reperfusion. La brièveté de la fenêtre temporelle de protection suggère que la rapidité d’obtention de la cible thermique est un élément clef dans le bénéfice permis par cette approche. / Ultra-fast cooling with total liquid ventilation and ischemia-induced multi-organ failureIschemia and reperfusion injury is a major challenge in anesthesiology and critical care. Resolution of the underlying condition and organ replacement therapies are the cornerstone of the treatment. Hypothermia exhibits a myriad of protective effects, but delays of application may blunt its benefits. Ultra-fast cooling with total liquid ventilation (TLV) is an emerging strategy, which consists in lung ventilation with cold perflurocarbons and uses the lungs as a heat exchanger while maintaining normal gas exchanges. Our objective was to investigate the effects of TLV-induced cooling during multiorgan failure caused by systemic ischemia-reperfusion in rabbits.In a first study, the application of 30 minutes of supraceliac aortic cross-clamping followed by 300 minutes of reperfusion led to severe multiorgan failure in control animals. On the contrary, animals submitted to hypothermic TLV reached the temperature of 33°C within less than 15 minutes. Hypothermia was maintained during 75 minutes before rewarming. This brief period of hypothermic TLV attenuated biochemical and histological markers of multiorgan failure. Cardiovascular and liver dysfunctions were limited by this short period of hypothermic TLV, even when started after reperfusion. Conversely, acute kidney injury was limited only when hypothermia was started before reperfusion.In a second study, non-shockable cardiac arrest from respiratory cause was responsible for a high rate of mortality and a severe post-cardiac arrest syndrome. Hypothermic TLV had potent neuro- and cardio-protective effects, as well as reduced inflammatory syndrome. Early preservation of the blood-brain barrier integrity and cerebral hemodynamics as well as reduction in the immediate reactive oxygen species production in the brain, heart, and kidneys were also notable.These studies demonstrate that ultra-fast cooling by TLV alleviates the deleterious effects of ischemia-reperfusion. The optimal duration and timing of TLV-induced hypothermia for end-organ protection in hypoperfusion states remains to be determined.

Master’s thesis is dealing with safety of workpiece clamping device. In the first part we are describing possibilities of clamping workpiece on different machines, legislative conditions in EU and CR in engineering devices, and general demands that refer to harmonized standards for different types of clamping devices. The main target of the thesis are the lists of requirements for hydraulic three-jaw chucks and proposal of two chosen safety applications. The first safety application refers to safety of clamping workpiece in hydraulic chuck. The second safety application is aimed at clamping of workpiece with the help of strap clamps. There is a description of the procedure of calculation of safe tightening moment during assembly of the nut.

This thesis descibes questions of tools for production of shape hollows focused especially on milling and electroerosion machining. Here you can find individual tools included their description and characteristics, toolmakers and their news. Here are mentioned methods and contemporary trend of cutting. Here is comparison of several tools in concrete applications. Included is also list of basic types of milling tools clamping. In conclustion there is mentioned further development of tools and their using.

Design servodrive clamping unit with pneumatic or mechanic multiplier. Unit has be instrumental to strength clamp parts in tension technical machines. Frame unit’s is complicate from massive and movable clamping board and is self-supporting. Unit has be solution like incorporated modulus. Target is proposal main driving period for movable clamping board. Work up proposal constructional solution, drawing listings, production drawing of the three engaged part of, BOM. Computational report must include calculations drives, constructional knots and their verification and further needed strength calculation and analyses. Proposal treatment tribotechnical knots. Analysis construction from standpoint safety in operation according to NV24/2003 and analysis safety hazards. Part of work must be and economic analysis resultant solution.

This master’s thesis deals with the design of the manipulator for rotating objects, especially workpieces, semifinished products, or complete products around horizontal axis. It’s the manipulator for objects where is needed change orientation during production process. This thesis describes step by step construction of individual components of the manipulator and calculations of propulsive units. At the beginning the conveyor roller with propulsive unit is designed. The next step is construction of scissor lift table and choice of the propulsive unit. There is also made FEM analysis for the scissor mechanism. The next unit is aimed to the construction and computation of rotating and telescopic jaw. Then hydraulic circuit with computation of the propulsive unit is designed. As the final step the appropriate type of sensors are chosen and the step diagram of the manipulator is made. The manipulator is designed in the 3D model program and there are also made some assembly drawings.

Diploma thesis deals with the concept of interchangeable straight spindle head type VA1-C, used for automatic clamping in 80 kW spindle head from production of TOS Kuřim. Thesis contains survey of interchangeable heads, analysis of the spindle housing, strenght analysis of the spindle with the safety calculations in critical sec-tions and analysis of the clamping mechanism together with the calculation of the camping force, which holds the tools in the spindle. Analysis of the camping mechanisms contains calculation of the contact stress between balls and housings. All results are shown in the graphs. In the last part of the thesis are described the construction elements using the model of the interchangeable head. Enclosed is the assembly drawing of the spindle head, bill of material, detail drawing of the spindle and also 3D model of the interchangeable spindle head.

Optimalizace procesu vrtání kovových materiálů vyžaduje minimální tvorbu otřepů a jednotný vzhled vrtaných děr. Cílem práce bylo pochopit roli různých klíčových faktorů, jako řezných podmínek, způsobu upnutí obrobku a geometrie vrtáku, na tvorbu otřepů při vrtání 2 mm plechů tvářené hliníkové slitiny Al99.7Mg0.5Cu-H24, za použití vrtáků o průměru 1,6 a 2 mm, pro dosažení minimalizace tvorby otřepů a zajištění jednotnosti získaných povrchů pro velký počet vrtaných děr v obrobku. Tohoto cíle bylo dosaženo provedením 3 experimentálních testů. První experimentální test byl proveden za účelem sledování vlivu řezné rychlosti a posuvu za otáčku, jakožto rozpoznaných řezných parametrů nejvýznamněji ovlivňujících tvorbu otřepů, na výsledné velikosti vzniklých otřepů a jednotnosti vrtaných děr. V druhém experimentu byl zkonstruován vakuový upínací přípravek, za účelem upnutí vrtaného hliníkového plechu a omezení prostoru pro tvorbu otřepů na výstupní straně vrtání na obrobku, a jeho vlivu na tvorbu otřepů bylo vyhodnoceno. V třetím testu byl vyhodnocen efekt rozdílných geometrií vrtáků na tvorbu otřepů, spolu s dosaženou jednotností vrtaných děr. Výsledky z prvního experimentu prokázaly, že výška a tloušťka otřepů je redukována na obou stranách vrtaného plechu za použití vyšších řezných rychlostí. Při použití vyšších posuvů byla viděna zvětšující se výška a tloušťka otřepů na obou stranách vrtání, s výjimkou výšky otřepů na vstupní straně vrtáku do obrobku, která byla minimálně snížena. Druhý experiment prokázal, že vhodně konstruovaný vakuový upínací přípravek může významně omezit vznik otřepů na výstupní straně vrtáku z obrobku. V třetím experimentu, za použití 3 břitého vrtáku a vhodně konstruovaného vakuového upínací ho přípravku, bylo dosaženo eliminace tvorby otřepů z obou stran vrtaného plechu, společně s naplněním požadavků na jednotný vzhled vrtaných děr a vysoké výrobní produktivity. Takovýto optimalizovaný proces, bez nutnosti použití přídavné operace na odstranění vzniklých otřepů, poskytuje významnou redukci výrobních nákladů. Mimoto jsou poskytnuta doporučení pro další výzkum k dosažení zlepšení ve výrobě.