Magister Scientiae Dentium - MSc(Dent) / Background: Most edentulous patients have expectations regarding complete dentures that are not only dependant on past experiences but also the information they received from others. These expectations may impact on the level of satisfaction the patient would have when receiving their complete dentures. When determining levels of satisfaction, factors such as comfort, speech, aesthetics, mastication, retention, fit / stability and occurrence of pain should be assessed. The dental student should be able to clinically apply theoretical knowledge to provide the patient with a stable and retentive denture that fulfils their expectations on function and aesthetics. Not much has been written regarding this link between patients' expectations and satisfaction with complete dentures at the University of the Western Cape, thus it warranted further investigation. Aim: The aim of this study was to determine whether patients' expectations influence their satisfaction with new complete dentures constructed by undergraduate dental students. Objectives:- 1. To determine the expectations of the edentulous patients prior to receiving new complete dentures. 2. To determine if patients’ expectations influences satisfaction with new complete dentures. 3. To investigate the influence of socio-demographic factors on patients' satisfaction wearing complete dentures. 4. To determine if the level of experience of the undergraduate student influences patient satisfaction. Methodology: This was an observational study using two questionnaires for data collection namely the Patient Expectation Questionnaire and the Oral Health Impact Profile- 20. Socio-demographic data was collected as part of the first questionnaire. Each participant was given an individual case number that corresponded on both questionnaires. This facilitated correlation between the expectations and satisfaction results of individual patients. Results: The age range for the majority of the patients was between 56-65 years. Females made up 72% of the sample with 85% of the sample of coloured ethnicity. Statistical analysis included reliability testing of the Patient Expectation Questionnaire and the Cronbach's Alpha of .773 was recorded, which indicates good reliability. Results following analysis of the Oral Health Impact Profile-20 showed high levels of satisfaction in most domains. The correlation between patients' expectations and satisfaction with new complete dentures was not proven using Pearson correlation. However, the comparison between the expectations questionnaire and Oral Health Impact Profile-20 frequency distribution showed positive results and most expectations of the patient were met or even exceeded for certain domains. Conclusion: Once analysis of both questionnaires was completed high levels of expectations were recorded and these expectations were met in most domains. Even though the statistical relationship between patient expectations and satisfaction was not proven, analysis of the questionnaires yielded positive results. No association was found between pre-treatment expectation and patient satisfaction with complete dentures. Some socio-demographic factors influenced patient satisfaction with complete dentures. High levels of patient satisfaction were recorded regardless of the clinical experience of the undergraduate dental student.

Title: The knapsack and its applications Author: Romana Linkeová Department: Department of Algebra Supervisor: doc. Mgr. Pavel Příhoda, Ph.D., Department of Algebra Abstract: This thesis is focused on various aspects of cryptosystems based on NP (non-deterministic polynomial) complete knapsack problem. From the theory of complexity point of view, the less known parts of the proof of knapsack problem NP completeness are shown in detail. From the cryptographical point of view, a demonstration of breaking of the Merkle-Hellman cryptosystem (the basic de- sign of knapsack-type cryptosystems) is provided, showing that poor parameters choice can lead to easy obtaining of the whole private key. Another contribution of this thesis consists in a presented proposal of a new cryptosystem concept based on the matrix 0-1 knapsack problem. This concept was developed in order to prevent known attacks, however, in the thesis we provide a proof analogous to J. C. Lagarias and A. M. Odlyzko, 1985, which shows that an attack based on the LLL algorithm will be successful on the majority of the matrix 0-1 kna- psack problem cryptosystems. Finally, a list of modern cryptosystems based on the knapsack problem is provided and a cryptanalysis thereof is given. Keywords: knapsack problem, NP complete problems, LLL algorithm 1

Magister Scientiae Dentium - MSc(Dent) / Aim: The aim of this study was to investigate the accuracy, intra- and inter-observer reliability of identifying occlusal markings made by articulating paper on complete dentures intra-orally. Methods: A series of photographs of 14 tissue borne complete dentures with occlusal markings was obtained. Articulating paper was used intra-orally at the delivery visit to make the occlusal markings. The denture sets were divided into two groups. Group 1 comprised pictures of the 14 complete lower dentures on their own, and group 2 comprised pictures of the same 14 lower dentures together with their opposing upper denture. The two groups of images were loaded into a Microsoft PowerPoint presentation as well as Keynote. Two experienced observers analysed the complete dentures independently and noted the number and distribution of the markings that they felt required adjustment. They differed, but discussed these and reached consensus. These data served as the control. Three groups of observers (10 per group) were then asked to analyse the occlusal markings of the 2 groups of denture images twice, with a two-week interval between each assessment. Before each subsequent assessment, the images were randomised by means of computer-generated random number sequence. The mean number of markings was established for each group and compared with the control mean. Intra-rater reliability was established by comparing the difference of the means of sequential observations for each rater by establishing the z-value. Inter-rater reliability within each group was established by means of analysis of variance. Results: Considering all the data, in only 17 instances (of the possible 60), did observers’ mean scores not differ from the control mean scores with good intra-rater reliability. In all other 43 instances the observers’ mean scores differed from the control mean scores and/or displayed poor intra-rater reliability. Considerable variation in inter-rater reliability was also found within every group of observers. Conclusion: The results indicate that observers are generally unable to reliably identify occlusal markings warranting occlusal adjustment, made by articulating paper on a lower complete denture. Clinical significance: Articulating paper should not be used intra-orally when delivering removable complete dentures.

The thesis deals with the financing of complete industrial plants exports with state support. The author is initially engaged in Export Strategy of the Czech Republic with an emphasis on companies founded by the state in order to support exports. Legislation in this field follows. The greatest emphasis is placed on methods of medium- and long-term export financing. One part of the thesis is a case study illustrating the possible practical way of financing export transactions.

Orientadores: Rafael Leonardo Xediek Consani, Mateus Bertolini Fernandes dos Santos / Dissertação (mestrado) - Universidade Estadual de Campinas, Faculdade de Odontologia de Piracicaba / Made available in DSpace on 2018-08-24T08:13:00Z (GMT). No. of bitstreams: 1 Caetano_ConradoReinoldes_M.pdf: 1244825 bytes, checksum: e99a928da45883acc1a5cc2ace6699fd (MD5) Previous issue date: 2014 / Resumo: O objetivo neste estudo foi avaliar a distribuição de tensões em overdentures com sistema de retenção tipo barra-clipe apresentando diferentes inclinações dos implantes, desajuste vertical e material da barra. Para isso foram confeccionados modelos tridimensionais de mandíbula e overdenture fixada por dois implantes com sistema de retenção barra-clipe que foram modelados com software específico (SolidWorks 2010) ... Observação: O resumo, na íntegra, poderá ser visualizado no texto completo da tese digita / Abstract: The aim of this study was evaluate the stress distribution in overdentures with a bar-clip retention system presenting different implant inclinations, vertical misfit, and framework materials. Three-dimensional models of a jaw, an overdenture retained by two implants and a bar-clip attachment were modeled using specific software (SolidWorks 2010) ... Note: The complete abstract is available with the full electronic document / Mestrado / Protese Dental / Mestra em Clínica Odontológica

Orientador: Rafael Leonardo Xediek Consani / Dissertação (mestrado) - Universidade Estadual de Campinas, Faculdade de Odontologia de Piracicaba / Made available in DSpace on 2018-08-26T21:39:48Z (GMT). No. of bitstreams: 1 Caldas_RicardoArmini_M.pdf: 2481955 bytes, checksum: f84eab0472b008e5bab4c2136a7f6b7e (MD5) Previous issue date: 2014 / Resumo: O uso de prótese total implanto-retida tem sido indicada atualmente como primeira opção de tratamento para uma mandíbula desdentada; no entanto, os fatores biomecânicos associados a ela não estão totalmente esclarecidos. O objetivo neste estudo foi avaliar por meio da análise tridimensional por elementos finitos o comportamento biomecânico do sistema de retenção barra-clipe para overdentures com barra de diferentes secções transversais (circular, oval e Hader), níveis de desajuste horizontal (50 e 150 µm) e inclinações em um dos implantes no sentido látero-lateral (-10, -5, 0, 5 e 10 graus). As angulações positivas (5 e 10 graus) dos implantes representam a inclinação da região cervical do mesmo para mesial, valores negativos (-10, -5 graus) inclinação para distal e o valor de 0 graus para os implantes paralelos. Os resultados foram obtidos de forma quantitativa e qualitativa em tensão de von Mises para os componentes protéticos, tensão máxima principal e deformação para o tecido ósseo. Foi observado que na inclinação 10 graus ocorreu o pior comportamento biomecânico, promovendo os maiores valores de tensão sobre a barra e tecido ósseo peri-implantar. Os grupos com inclinação negativa (distal) apresentaram os menores valores de tensão sobre os componentes protéticos e na inclinação -10 graus foi observado o menor valor de deformação no tecido ósseo peri-implantar. O aumento do desajuste horizontal aumentou os valores de tensão em todas as estruturas avaliadas. A seção da barra não demonstrou influência nas tensões geradas. Concluiu-se que a inclinação do implante para mesial aumentou a tensão em todos os componentes e a maior inclinação (10 graus) causou os maiores valores; os implantes com inclinação para distal geraram os menores valores de deformação no tecido peri-implantar. As diferentes secções transversais da barra não influenciaram os valores de tensão em todos os componentes do sistema / Abstract: The most common treatment for edentulous patients is conventional denture. However, implant-retained prosthodontics is actually the first option for treatment of these patients. The aim of this study was to evaluate by 3-D finite element analysis the biomechanics involved in the bar clip retention system for overdentures. The study factors were latero-lateral angulation in the right implant (-10, -5, 0, 5 and 10 degrees); horizontal misfit on the left implant (50 e 150 µm), and bar cross-section (round, Hader and oval). Positive angulation (5 and 10 degrees) means inclination of the implant to mesial position, negative values (-5 and -10 degrees) for distal position and zero degress for parallel implants. The von Mises stresses evaluated the prosthetic components; maximum principal stresses, and strain analyses evaluated the peri-implantar bone. The positive angulation (10 degrees) showed the worse biomechanical behavior for bar and peri-implantar bone, with higher stress concentration. Conversely, the negative angulation showed the lowest stress deformation to the peri-implantar bone. The amplitude of horizontal misfit was directly proportional to stress concentration. Bar Cross-sections did not affect the stress distribution. It was possible to conclude that: the mesial implant angulation produced more stresses in the prosthetic components; distal angulation showed better biomechanical behavior; and bar cross-section had no influence on stress distribution / Mestrado / Protese Dental / Mestre em Clínica Odontológica

Dengue é uma doença infecciosa não contagiosa causada pelo vírus da dengue (gênero Flavivirus, família Flaviviridae), transmitida pela picada de artrópodes do gênero Aedes, principalmente Aedes aegypti, e sendo atualmente um importante problema de saúde pública em todo o mundo. Segundo a Organização Mundial de Saúde, cerca de 50 a 100 milhões de pessoas se infectam anualmente em mais de 100 países de todos os continentes. A dengue apresenta-se em três formas clínicas principais; doença febril indiferenciada, febre clássica do dengue (DF) e dengue hemorrágico com ou sem choque (DHF/DSS). Recentemente, viu-se um dramático aumento do número de casos de DHF/DSS nas Américas, e este aumento coincidiu com a introdução do dengue tipo 3, genótipo III. Neste trabalho, caracterizamos completamente o genoma de um vírus brasileiro de dengue tipo 3 (D3BR/RP1/2003) isolado de um paciente com dengue clássica. O genoma viral possui um tamanho de 10707 nucleotídeos e contém uma única região codificadora (posição 95 a 10264) flanqueada por duas regiões não codificadoras (RNC5, 1 a 94; RNC3, 10268 a 10707). A comparação do genoma viral com outros vírus isolados de pacientes com DF e DHF não mostrou diferenças significativas que sugerissem a presença de um fator genético associado à virulência. A analise filogenética baseada no genoma completo, mostra que a cepa D3BR/RP1/2003 pertence ao genótipo III e encontra-se proximamente relacionada a outro vírus isolado no Rio de Janeiro em 2002. Entretanto, quando essa análise filogenética é realizada com as regiões codificadoras das proteínas E e NS5 individualmente, a cepa D3BR/RP1/2003 encontra-se mais proximamente relacionada a um vírus isolado na Ilha de Martinica no Caribe. Este achado sugere que o isolado D3BR/RP1/2003 pode ter sido originado através de um evento de recombinação entre duas cepas virais distintas antes ou após sua introdução no Brasil. Dados sugestivos de recombinação foram observados também quando analisada a relação filogenética entre vírus isolados na Ásia. / Dengue is an infectious disease caused by dengue virus (genus Flavivirus, family Flaviviridae), transmitted by the bite of arthropods of the Aedes genus, mainly Aedes aegypti, and being currently an important problem of public health worldwide. According to the World Health Organization, about 50 the 100 million people are infected annually in more than 100 countries of all continents. Dengue can be presented in three main clinical forms; undifferentiated febrile illness, classic dengue fever (DF) and hemorrhagic dengue fever with or without shock (DHF/DSS). Recently, a dramatically increase of DHF/DSS cases in the Americas have been seen, and this increase coincided with the introduction of the dengue type 3, genotype III. In this work, we have completely characterized the genome of a Brazilian dengue type 3 (D3BR/RP1/2003 strain) isolated from a DF patient. The viral genome possesses a size of 10707 nucleotides and has a unique open reading frame (position 95 to 10264), flanked by two untranslated regions (UTR5\', 1 to 94; UTR3\', 10268 to 10707). The comparison of the viral genome with other viruses isolated from patients with DF and DHF did not show significant differences to suggest the presence of a genetic factor associate with virulence. Phylogenetic analysis based on the complete genome showed that D3BR/RP1/2003 strain belongs to genotype III and is close related to another virus isolated in Rio de Janeiro in 2002. However, when the phylogenetic analysis was based on the individual coding regions of E and NS5 proteins, D3BR/RP1/2003 strain was closely related to a virus isolated in the Island of Martinique in the Caribbean. This finding suggests that D3BR/RP1/2003 strain could have been originated through an event of recombination between different virus strains before or after its introduction to Brazil. Data supporting recombination events between viruses isolated in Asia have also been observed.

O objetivo deste estudo foi avaliar a eficiência mastigatória de usuários de prótese parcial removível (PPR) classe I inferior e prótese total (PT) superior, da cidade de Porto Velho - Rondônia, e comparar os resultados obtidos com os descritos na literatura, utilizando a mesma metodologia. Dez indivíduos (cinco do gênero feminino e cinco do gênero masculino) totalmente dentados foram selecionados para o grupo controle. Vinte e sete indivíduos, de ambos os gêneros, receberam 17 cubos de Optocal (simulador de alimento) os quais foram mastigados em vinte ciclos (golpes) mastigatórios. O mesmo procedimento foi repetido posteriormente, desta vez com quarenta ciclos. Os fragmentos foram passados por oito peneiras granulométricas calibradas (5,6; 4,0; 2,8; 2,0; 1,4; 1,0; 0,71 e 0,5 mm) e depositado em um coletor sem perfurações. O material triturado, retido em cada peneira e no coletor, foi secado em estufa e pesado. Os valores foram tabulados em tabela e analisados. Após a mastigação, os indivíduos responderam um questionário para qualificar o alimento utilizado quanto à natureza, consistência, influência do sabor e grau de dificuldade de mastigação. Os resultados mostram melhor eficiência mastigatória em pacientes totalmente dentados, com quarenta ciclos mastigatórios e que, para compensar o fraco desempenho mastigatório das próteses removíveis, os pacientes devem realizar mais golpes mastigatórios. / The aim of this study was evaluate the masticatory efficiency of removable partial denture (RPD) of wearers class I mandibular and complete denture maxillar in Porto Velho, Rondônia. Ten completely dentate subjects (five women and five men) were selected to the control group. Twenty seven subjects both gender were selected and received 17 Optocal cubes (food simulator) that were chewed in twenty chewing strokes. The same procedure was used on late with forty chewing strokes. The fragments of Optocal were sieved on stacks of eight sieves, with apertures from 5,6 decreasing to 0,5 mm (5,6; 4,0; 2,8; 2,0; 1,4; 1,0; 0,71 e 0,5 mm), and a bottom plate. The amount of test food on each sieve and on the bottom plate was dried and measured. The results were tabled and analyzed. After the chewing test, the subjects answer a questionnaire to qualify the test food in relation to hardness, consistency and difficulty to chew. The results show better masticatory efficiency in subjects completely dentates with 40 chewing strokes and that, to compensate the removable denture low performance, the patients must do extra masticatory bites.

Akut stroke är en allvarlig och livshotande sjukdom som ofta leder till fysiska och kognitiva funktionsnedsättningar. Riksstroke är ett kvalitetregister som samlar in och tillhandahåller information om strokevården i Sverige. Under 2019–2020 pågår ett omfattande valideringsarbete där analys av bortfallet inom registret utförs. Syftet med uppsatsen var att som i en del av detta arbete analysera omfattningen av bortfallet i flera faktorer och om det fanns en skillnad mellan grupperna kön, ålder och sjukhus. Därefter testades två metoder för bortfallshantering, complete case analysis och multipel imputations by chained equation (MICE). Dessa utvärderades genom att jämföra de skattade oddskvoterna för död inom 90 dagar efter inskrivning på sjukhus. Resultatet visade att det fanns stora skillnader i bortfall mellan män och kvinnor, åldersgrupper och sjukhusen. Där kan en stor del av skillnaden i bortfall troligtvis kan förklaras av åldern på patienterna. Det två utvärderade metoderna producerade jämförbara resultat.

abstract: Bivariate responses that comprise mixtures of binary and continuous variables are common in medical, engineering, and other scientific fields. There exist many works concerning the analysis of such mixed data. However, the research on optimal designs for this type of experiments is still scarce. The joint mixed responses model that is considered here involves a mixture of ordinary linear models for the continuous response and a generalized linear model for the binary response. Using the complete class approach, tighter upper bounds on the number of support points required for finding locally optimal designs are derived for the mixed responses models studied in this work. In the first part of this dissertation, a theoretical result was developed to facilitate the search of locally symmetric optimal designs for mixed responses models with one continuous covariate. Then, the study was extended to mixed responses models that include group effects. Two types of mixed responses models with group effects were investigated. The first type includes models having no common parameters across subject group, and the second type of models allows some common parameters (e.g., a common slope) across groups. In addition to complete class results, an efficient algorithm (PSO-FM) was proposed to search for the A- and D-optimal designs. Finally, the first-order mixed responses model is extended to a type of a quadratic mixed responses model with a quadratic polynomial predictor placed in its linear model. / Dissertation/Thesis / Doctoral Dissertation Statistics 2020