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Effects of deep breathing exercises after coronary artery bypass surgery /Westerdahl, Elisabeth, January 2004 (has links)
Diss. (sammanfattning) Uppsala : Univ., 2004. / Härtill 4 uppsatser.
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On cellular sources for intimal hyperplasia after vascular interventions /Mellander, Stefan, January 2007 (has links)
Diss. (sammanfattning) Göteborg : Göteborgs universitet, 2007. / Härtill 4 uppsatser.
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Wound infection following coronary artery bypass graft surgery : risk factors and the experiences of patients /Swenne, Christine Leo, January 2006 (has links)
Diss. (sammanfattning) Uppsala : Uppsala universitet, 2006. / Härtill 4 uppsatser.
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Quality of life following coronary artery surgery with cardipulmonary bypass: the effects of post-operative cognitive impairments and pre-surgery symptoms of depression and trait anxiety /Barr, Francine January 1900 (has links)
Thesis (M.A.) - Carleton University, 2004. / Includes bibliographical references (p. 76-82). Also available in electronic format on the Internet.
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Effects of an expanded rehabilitation programme in patients with ischemic heart diseaseEdström Plüss, Cathrine. January 2009 (has links)
Lic.-avh. (sammanfattning) Stockholm : Karolinska institutet, 2009.
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Bayesian based risk stratification of atrial fibrillation in coronary artery bypass graft patientsWiggins, Matthew Corbin. January 2007 (has links)
Thesis (Ph.D.)--Bioengineering, Georgia Institute of Technology, 2007. / Committee Co-Chair: Litt, Brian; Committee Co-Chair: Vachtsevanos, George; Committee Member: Butera, Robert; Committee Member: Frazier, Bruno; Committee Member: Gerstenfeld, Edward; Committee Member: Hunt, William.
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Sintomas depressivos e experiência pessoal de pacientes submetidos à cirurgia eletiva de revascularização do miocárdio / Depressive symptoms and personal experience of patients undergoing elective surgery for coronary artery bypass graftingUliana, Maithê Cristina [UNESP] 26 February 2016 (has links)
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Previous issue date: 2016-02-26 / A crescente associação entre depressão e doenças cardiovasculares aponta para a influência de fatores psicoemocionais no aparecimento de doenças cardíacas, como é o caso da Doença Arterial Coronariana (DAC). Estudos apontam para a alta prevalência de sintomas de depressão em pacientes com DAC, antes e após a cirurgia de revascularização do miocárdio (CRM). Destacam-se os aspectos emocionais vivenciados pelos pacientes frente à experiência da cirurgia cardíaca, desde sua descoberta até o processo de recuperação. A vivência como Psicóloga na Unidade de Cardiologia de um Hospital Geral mobilizou o interesse em investigar o fenômeno depressivo e os aspectos psicológicos relacionados à experiência da cirurgia cardíaca dos pacientes submetidos à CRM, tendo em vista a importância do tratamento, prevenção e minimização dos riscos relacionados ao quadro orgânico. Neste estudo, de natureza quanti-qualitativa, os sintomas depressivos de 20 pacientes submetidos à CRM foram avaliados nos momentos pré e pós-operatórios, durante a internação hospitalar. As experiências pessoais em relação à doença e à cirurgia cardíaca de 5 destes pacientes, relatadas em entrevistas clinicas no pós-operatório tardio, foram descritas e analisadas, bem como a avaliação dos sintomas de depressão neste momento. Os 20 participantes admitidos na Unidade de Cardiologia do Hospital de Base de Bauru – SP FAMESP, pertenciam a ambos os sexos, situavam-se na faixa etária de 53 a 77 anos, haviam sido diagnosticados com DAC e recebido indicação de CRM. A etapa da internação hospitalar englobou a avaliação dos sintomas de depressão por meio do Inventário de Depressão de Beck-II (BDI-II), e o registro de dados demográficos, clínico-médicos e psicológicos pela Ficha de Registro de Dados de Prontuário, e teve os dados analisados quantitativamente. A análise estatística consistiu da descrição da prevalência e intensidade dos sintomas depressivos e dos dados clínico-médicos e psicológicos em frequências absolutas (N) e relativas (%). Para a comparação das frequências foram utilizados os testes não paramétricos de McNemar e Wilcoxon, adotando-se o nível de significância estatística de α = 0,05. A maioria da amostra foi composta por pacientes acima dos 60 anos de idade (75%) e do sexo masculino (60%). Os resultados obtidos apontam para a alta prevalência de sintomas de depressão em pacientes com DAC, antes e após a CRM, não se constatando mudanças significativas em relação à presença de sintomatologia depressiva entre o pré e o pós-operatório da cirurgia. A intensidade dos sintomas depressivos melhorou entre o pré e pós-operatório, possivelmente devido à sensação de alívio após o procedimento cirúrgico, e à expectativa de melhora da condição física e da qualidade de vida no período de recuperação da cirurgia A análise qualitativa das entrevistas dos cinco casos clínicos, por meio da técnica de análise de conteúdo de Bardin (1977), revelou o caráter positivo da experiência da cirurgia cardíaca, na qual a fé e a religiosidade, o suporte familiar e o suporte oferecido pela equipe multidisciplinar, em especial do psicólogo, foram apontados como importantes recursos para enfrentar o impacto do diagnóstico da enfermidade cardíaca, a indicação da cirurgia e as dificuldades relacionadas ao processo de hospitalização. / The increasing association between depression and cardiovascular disease points to the influence of psycho-emotional factors in the onset of heart disease, as is the case with Coronary Artery Disease (CAD). Studies point to the high prevalence of depression symptoms in CAD patients before and after coronary artery bypass graft (CABG) the emotional aspects are. It highlights the emotional aspects experienced by patients across the experience of heart surgery, since its discovery until the recovery process. The experience as a Psychologist in the Cardiology Unit of a general hospital mobilized the interest in investigating the depressive phenomenon and the psychological aspects related to the experience of heart surgery patients undergoing CABG, considering the importance of treatment, prevention and minimization of related risks the organic framework. In this study, a quantitative and qualitative nature, the depressive symptoms of 20 patients undergoing CABG were evaluated in the pre and postoperative, during hospitalization. Personal experiences about the disease and cardiac surgery in 5 of these patients reported in clinical interviews in the late postoperative period, were described and analyzed, as well as evaluating the symptoms of depression at the moment. The 20 participants admitted to the Cardiology Unit of the Base Hospital of Bauru - SP FAMESP belonged to both sexes, were in the age group 53-77 years had been diagnosed with CAD and CRM received indication. The stage of hospitalization included the assessment of depression symptoms via the Beck Inventory-II Depression Inventory (BDI-II), and the record of demographic data, clinical and medical and psychological the Handbook of Data Recording Sheet, and had the data analyzed quantitatively. Statistical analysis is the description of the prevalence and intensity of depressive symptoms and clinical and medical and psychological data in absolute frequencies (N) and relative (%). To compare the frequency nonparametric McNemar test and Wilcoxon were used, adopting the statistical significance level of α = 0.05. The majority of the sample consisted of patients over 60 years of age (75%) and male (60%). The results point to the high prevalence of symptoms of depression in patients with CHD before and after CABG and contains no significant changes regarding the presence of depressive symptoms between pre and postoperative surgery. The intensity of depressive symptoms improved between the pre- and post-operative, possibly due to the sense of relief after surgery, and the expectation of improving their physical condition and quality of life in the surgery recovery period. The qualitative analysis of five clinical cases through the Bardin content analysis technique (1977), revealed the positive nature of the experience of heart surgery, in which faith and religiosity, family support, and the support offered by the multidisciplinary team, especially the psychologist, were identified as important resources used to address the impact of the diagnosis of heart disease, the indication of surgery and difficulties related to the hospitalization process.
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Myocardial and cerebral preservation during off-pump coronary artery surgeryPenttilä, H. (Hannu) 18 January 2006 (has links)
Abstract
Interest in off-pump coronary surgery and ischaemic preconditioning has been increasing. The aim of this study was to evaluate surrogate indicators of haemodynamic, myocardial, and cerebral outcome during off-pump surgery and preconditioning.
Haemodynamics and myocardial preservation were monitored in a pilot study of twelve patients undergoing off-pump coronary surgery. Indicators of myocardial metabolism and tissue injury as well as cerebral damage were evaluated in a randomized study of thirty-three patients undergoing on-pump (11) or off-pump surgery with (11) or without (11) preceding myocardial ischaemic preconditioning for five minutes followed by reperfusion for five minutes.
The pilot study showed minimal haemodynamic changes and myocardial derangements during off-pump surgery as evaluated intraoperatively based on transcardiac differences of ATP degradation products and lactate and postoperatively based on MB mass of creatine kinase and troponin T.
In the following studies, myocardial ischaemic metabolism was evaluated intraoperatively by measuring transcardiac differences of ATP degradation products, lactate, and pH, which increased significantly from the baseline values in all study groups. However, the maximum values of lactate and pH were significantly higher in the cardiopulmonary bypass group (p = 0.02 and p = 0.007, respectively). There were no statistical differences between the preconditioning and non-preconditioning groups. Myocardial tissue injury was evaluated by postoperative leakage of MB mass of creatine kinase and troponin I. Their peak values were significantly higher (p < 0.001 and p = 0.008) after cardiopulmonary bypass (15.1 μg/l and 13.8 μg/l) than after off-pump surgery without preconditioning (6.3 μg/l and 5.2 μg/l). The respective values were 14.8 μg/l and 7.4 μg/l after preconditioning, and there were no statistically significant differences between the off-pump groups with and without preconditioning. Cerebral damage was evaluated based on the intra- and postoperative serum concentrations of neuron-specific enolase, which were corrected with respect to haemolysis. The corrected values were significantly higher after on-pump than off-pump surgery (p = 0.003 and p = 0.005).
In conclusion, multi-vessel off-pump coronary artery surgery is a haemodynamically feasible procedure offering better myocardial preservation compared to on-pump surgery. Ischaemic preconditioning of the myocardium does not seem to improve myocardial preservation in off-pump surgery. The slightly lower levels of neuron-specific enolase also suggest less cerebral damage.
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Cellular Cardiomyoplasty: A Preliminary Clinical ReportZhang, Fumin, Gao, Xiang, Yiang, Zhi Jian, Ma, Wenzhu, Li, Chuanfu, Kao, Race L. 01 January 2003 (has links)
Background: Cellular cardiomyoplasty is the method of transplanting myogenic cells into injured myocardium to restore the lost heart muscle cells and to improve ventricular function. Method: Three patients, all with a history of coronary heart disease, underwent coronary artery bypass grafting and implantation of autologous satellite cells. A muscle biopsy of 2-4 g from the right vastus lateralis muscle was obtained for satellite cell (myogenic stem cell from skeletal muscle) isolation and proliferation before implanted into the donor's heart. The cells were suspended in serum-free medium and injected into 30-40 sites at and around the ischemic areas just before reversing the hypothermic cardioplegia to eliminate arrhythmia and to improve retention. After recovery, each patient was maintained at the intensive care unit for 3-4 days with ECG monitoring before transferring to the patient floor. Results: All patients survived the procedure with an uneventful recovery and were discharged from the hospital. At 3-4 months follow-up examination, increased left ventricular ejection fraction of 11% (35-46%), 5.4% (40-45.4%) and 1% (40-41%) and decreased left ventricular diastolic diameter of 4, 2 and 9 mm were observed for the patients, respectively. Arrhythmia was not detected during the follow-up evaluation by ECG. Improved perfusion (99mTC-MIBI) and increased metabolic activity (18F-deoxyglucose) were found at the sites of satellite cell implantation. Significant increase of wall thickness and movement at the areas of cell injection was also observed using 2D-echo. Conclusion: Cellular cardiomyoplasty using autologous satellite cells is a safe procedure with encouraging beneficial outcomes in patients.
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Percutaneous Coronary Intervention Versus Coronary Artery Bypass Grafting in Treatment of Unprotected Left Main StenosisTaha, Yasir, Patel, Rajan A.G., Bagai, Jayant, Sachdeva, Rajesh, Kumar, Gautam, Prasad, Anand, Nathan, Sandeep, Paul, Timir K. 01 May 2019 (has links)
Purpose of Review: This article reviews the latest data on unprotected left main (ULM) percutaneous coronary intervention (PCI) versus coronary artery bypass graft (CABG) surgery, with a focus on the NOBLE and EXCEL trials. Recent Findings: In EXCEL trial, the primary endpoint at 3 years was 15.4% in the PCI group and 14.7% in the CABG group (p = 0.02 for non-inferiority of PCI versus CABG). In NOBLE, the primary endpoint at 5 years was 28% and 18% for PCI and CABG, respectively (HR 1.51, CI 1.13–2.0, which did not meet the criteria for non-inferiority of PCI to CABG; p for superiority of CABG was 0.0044). Higher repeat revascularization and non-procedural myocardial infarction were noted in PCI group but there was no difference in all-cause or cardiac mortality between the two groups. Summary: A heart team approach with appropriate patient selection, careful assessment of LM lesions, and meticulous procedural technique makes PCI a valid alternative to CABG for ULM stenosis.
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