The adjustment and assimilation achieved by Cuban-Americans who arrived in Oregon during the 1960s was notable for its rapidity. Little contact existed between the state and the island prior to the resettlement efforts begun by the Charities Division of the Portland Catholic Archdiocese, where a group of concerned administrators meshed their activities with a nation-wide program created and encouraged by the united States government and private agencies.

Thesis--Michigan State University, 1973. / Bibliography: p. 192-196.

Type 2 Diabetes (T2D) disproportionally affects ethnic minorities in the United States. The development of T2D involves complex interaction between environmental factors and genetic predisposition. The genetic associations of six single nucleotide polymorphisms (SNPs) in TCF7L2 gene with the risk of T2D were evaluated in three high risk minority populations: Cuban Americans, Haitian Americans, and African Americans. For Cuban Americans, four SNPs (rs7901695, rs4506565, rs7903146 and rs11225537) were significantly associated with the risk of T2D after multivariable adjustment (p=0.018, p=0.016, p=0.014, and p=0.0008, respectively). Among controls, risk allele carriers of SNPs rs7901695, rs4506565 and rs7903146 had significantly higher fasting glucose level, compared to non-risk allele carriers. Additionally, a significant interaction between dietary fiber intake and SNP rs7903146 for the risk of T2D (p= 0.044) was found in Cuban Americans. Similarly, for SNP rs7901695, significant interaction was also found for fiber intake (p=0.014) as well as glycemic load (p=0.040). Subgroup analysis revealed that significant associations were only found within higher intake groups of dietary factors for both SNPs. For Haitian Americans, SNPs rs11196205 (p=0.059) and rs7895340 (p=0.069) showed marginal significance for the risk of T2D. After stratification by gender, SNPs with marginal significance from the gender-combined analysis became statistically significant with the same trend for the risk of T2D when analysis were done in males: rs11196205 (p=0.034) and rs7895340 (p=0.024). For African Americans, SNP rs7903146 (p=0.065) showed a marginal significance with the risk of T2D in gender-combined analysis and a statistical significance (p=0.013) in males. Two additional SNPs rs7901695 and rs4506565 were found to be significantly associated with the risk of T2D in males. Risk allele carriers of these two SNPs had significantly higher mean level of the fasting glucose level, compared to non-risk allele carriers in controls. T2D related quantitative trait analysis also demonstrated that in controls, compared to non-minor allele carriers of SNP rs12255372, minor allele carriers had significantly higher means of BMI, diastolic blood pressure, numbers of components of Metabolic Syndrome, significantly lower mean values of HDL-cholesterol and adiponectin. Taken together, our studies demonstrated ethno-specific genetic associations between TCF7L2 gene and the risk of T2D and related phenotypes.

Made available in DSpace on 2014-06-11T19:28:04Z (GMT). No. of bitstreams: 0 Previous issue date: 2008-07-24Bitstream added on 2014-06-13T20:57:42Z : No. of bitstreams: 1 morrone_p_me_mar.pdf: 511209 bytes, checksum: bdbd295a6628155bd53961c752aeed05 (MD5) / Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) / Esta dissertação tem como objetivo analisar a atuação dos cubano-americanos organizados sob a Fundação Nacional Cubano Americana (FNCA) na política externa dos Estados Unidos para Cuba. Para tanto, abordamos o processo migratório cubano para os Estados Unidos, com ênfase no período posterior à Revolução Cubana, quando essa emigração passa a ser concebida como base social da contra-revolução e promovida pelo governo norte-americano. Nessa direção, apresentamos o tratamento particular oferecido a essa emigração pela administração Ronald Reagan, que estimulou a formação da FNCA como uma organização política contrarevolucionária capaz de pressionar o Congresso em temas cubanos, e a inserção dos cubanos organizados sob esta instituição na vida doméstica do país, sinalizada por seus votos e por suas contribuições financeiras às campanhas eleitorais. Por fim, analisamos os atuais objetivos da FNCA, traduzidos na promoção de uma transição política em Cuba para a democracia e favorecidos pela administração George W. Bush, que financia e apóia programas para esse fim. / This dissertation has as objective to analyse the cuban-americans’ role, organized under the Cuban American National Foundation (CANF), in the United States’ foreign policy towards Cuba. For this purpose, we analyzed the cuban migration process directed to the United States, emphasizing the post Revolution period, when this emigration is conceived as the social basis of the counter-revolution and promoted by the U.S. government. In this direction, we presented the particular treatment offered to this emigration by the Reagan administration, which stimulated the CANF creation as a counter-revolutionary political organization capable of pressing the Congress in cuban themes, and the insertion of the cubans organized under this institution in the domestic affairs of the country through their votes and financial contributions. Finally, we analyzed the actual objectives of CANF, translated in the promotion of a political transition in Cuba for democracy and favored by Bush’s administration, which finances and supports programs towards this end.

Orientador: Luís Fernando Ayerbe / Banca: Héctor Saint-Pierre / Banca: Harry E. Vanden / O Programa de Pós-Graduação em Relações Internacionais é instituído em parceria com a Unesp/Unicamp/PUC-SP, em projeto subsidiado pela CAPES, intitulado "Programa San Tiago Dantas" / Resumo: Esta dissertação tem como objetivo analisar a atuação dos cubano-americanos organizados sob a Fundação Nacional Cubano Americana (FNCA) na política externa dos Estados Unidos para Cuba. Para tanto, abordamos o processo migratório cubano para os Estados Unidos, com ênfase no período posterior à Revolução Cubana, quando essa emigração passa a ser concebida como base social da contra-revolução e promovida pelo governo norte-americano. Nessa direção, apresentamos o tratamento particular oferecido a essa emigração pela administração Ronald Reagan, que estimulou a formação da FNCA como uma organização política contrarevolucionária capaz de pressionar o Congresso em temas cubanos, e a inserção dos cubanos organizados sob esta instituição na vida doméstica do país, sinalizada por seus votos e por suas contribuições financeiras às campanhas eleitorais. Por fim, analisamos os atuais objetivos da FNCA, traduzidos na promoção de uma transição política em Cuba para a democracia e favorecidos pela administração George W. Bush, que financia e apóia programas para esse fim. / Abstract: This dissertation has as objective to analyse the cuban-americans' role, organized under the Cuban American National Foundation (CANF), in the United States' foreign policy towards Cuba. For this purpose, we analyzed the cuban migration process directed to the United States, emphasizing the post Revolution period, when this emigration is conceived as the social basis of the counter-revolution and promoted by the U.S. government. In this direction, we presented the particular treatment offered to this emigration by the Reagan administration, which stimulated the CANF creation as a counter-revolutionary political organization capable of pressing the Congress in cuban themes, and the insertion of the cubans organized under this institution in the domestic affairs of the country through their votes and financial contributions. Finally, we analyzed the actual objectives of CANF, translated in the promotion of a political transition in Cuba for democracy and favored by Bush's administration, which finances and supports programs towards this end. / Mestre

Thesis (M.A.)--Miami University, Dept. of History, 2008. / Title from first page of PDF document. Includes bibliographical references (p. 26-31).