Die junge slowenische Musikwissenschaftlerin hat sich in ihrer Dissertation dem Leben und Werk des Komponisten und Orgelmachers Isaac Posch (1591? - 1623) gewidmet.

Digital forensics examiners have a growing problem caused by their own success. The need for digital forensics is increasing and so are the devices that need examining. Not only are the number of devices growing, but so is the amount of information those devices can hold. One result of this problem is a growing backlog that could soon overwhelm digital forensics labs across the country. One way to combat this growing problem is to use digital triage to find the most pertinent information first. Unfortunately, although several digital forensics models have been created, very few digital triage models have been developed. This results in most organizations, if they perform digital triage at all, performing digital triage in an untested ad hoc fashion that varies from office to office. This dissertation will contribute to digital forensics science by creating and testing a digital triage model. This model will be semi-automated to allow for the use by untrained users; it will be as operating system independent as possible; and it will allow the user to customize it based on a specific crime class or classes. The use of this model will decrease the amount of time it takes a digital triage examiner to make a successful assessment concerning evidence.

This dissertation is an attempt to develop an Augustinian response to political problems diagnosed by Michel Foucault's analysis of modern political power. Foucault argues that the primary acts of power in the modern age are not repressive acts but creative ones. Instead of prohibiting acts, political power disciplines, rehabilitates and normalizes. The result of this is a disciplined and docile subject within which relations of power are so deeply embedded that 'liberation' can only bring about their entrenchment and the absorption of all aspects of life into the political structures they represent. Foucault's alternative consists in practices of aesthetic self-creation not linked to transcendent or natural construals of order. William Connolly extends Foucault's argument by criticizing Augustine as a thinker projecting a moral order onto the world and then categorizing the world on the basis of this order. This contrasts with Connolly's attempt to derive political practice from ethical sources that do not attempt to order the cosmos unambiguously . I use John Milbank to begin an Augustinian response as Milbank understands Augustine as developing an ontology grounded in the priority of peace and plenitude to violence and scarcity. This provides the basis for my argument that within Augustine's account of the purposive nature of love and desire within the subject lies an implicit critique of Foucault's ethic of aesthetic self-creation. What follows this is an attempt to outline the significant characteristics of a political posture formed by the practice of the Eucharist. These characteristics provide an alternative to both modem political practice and Foucauldian practice. The final chapter applies this Augustinian political posture to the realms of sexuality, on one hand, and punishment and discipline, on the other. / Thesis / Doctor of Philosophy (PhD)

Historically, the doctoral dissertation has had two purposes: to train young scholars in proper research methodology, and to contribute original findings to research. However, some feel that the traditional dissertation format falls short of these goals for two reasons. First, the majority of dissertations never get published in academic journals, and dissertations are unlikely to get cited in academic articles. Second, many students in doctoral programs see little authenticity in traditional dissertations because the writing style and process differ from that of academic articles. In response to these concerns, many Instructional Technology programs have implemented alternative dissertation formats. This study used survey data to investigate the benefits, challenges, perceptions and current practices of alternative dissertation formats in Instructional Technology. Online surveys were sent to 74 students, 61 alumni, and 38 faculty of Instructional Technology programs in 2010, and 78 students, 43 alumni, and 12 department representatives in 2014. Data were analyzed using qualitative and quantitative methods. Surveys found that alumni who completed alternative dissertation formats received more citations for their dissertations than those who completed traditional dissertations, showing that alternative dissertations increase the likelihood of impact. Additionally, respondents reported that alternative dissertation formats facilitate authenticity and collaboration, and prepare students for a career in academia. However, some participants perceived alternative dissertations as less rigorous than traditional dissertations, with ambiguous requirements and expectations of quality. More research is needed in order to understand current practices for alternative dissertation formats in Instructional Technology.

Ligand-targeted therapeutics are a rapidly growing class of anticancer agents. This class of therapeutics is typically bifunctional molecules that use a targeting moiety to selectively deliver potent, typically nonspecific, cytotoxic agents to cancer cells while sparing normal cells. The low-molecular-weight of ligant-targeted therapeutics allows for better tumor penetration, especially in the case of solid tumors where the size of antibodies is a limiting factor for effective treatment. Unfortunately, the poor pharmacokinetic profiles of many of these conjugates present a challenge, which limits their tremendous therapeutic potential. Dose-limiting toxicity is also observed due to the need for high doses and frequent administration. This dissertation describes our work to develop a fundamentally new approach for targeting cancer. Our approach could potentially reduce the toxicity and enhance the pharmacokinetic properties of targeted anticancer agents, which would decrease dosing frequency and improve the lives of cancer patients.

The data presented in this thesis highlights how sea water composition and biological activity can affect the morphology, composition, organic volume fraction, and hygroscopicity of individual sea spray aerosols (SSA). A variety of techniques were used to measure seawater and aerosol composition with the emphasis placed on spatial chemical composition obtained through Scanning Transmission X-ray Microscopy-Near Edge X-ray Absorption Fine Structure (STXM-NEXAFS). Through NEXAFS data, organic volume fractions were derived from Beer's Law, and spatially resolved chemical composition for individual particles were determined through application of singular value decomposition and principal component analysis. These methods were applied to two specific studies: a 30 day mesocosm study using a wave flume termed Investigation into Marine PArticle Chemistry and Transfer Science (IMPACTS) and a smaller scale collection of SSA generated from a miniature Marine Aerosol Reference Tank (mini-MART) with bacteria enriched sea water. For IMPACTS, two consecutive phytoplankton blooms were observed; however, organic enrichment in sea spray aerosols only occurred during one of the blooms. STXM-NEXAFS measurements revealed four distinct particle types: sea salt-organic particles with a distinct NaCl core and an organic carbon coating, homogenously mixed organic-inorganic particles, calcium-rich needle-like particles, and agglomerations of optically thick organic material with inorganic salts. Organic enrichment was correlated with aliphatic-rich organic species as detected by an intense Cls—•a(C-H)* exciton excitation. This enrichment was unique to particles collected in the aerodynamic size range 0.18-0.32 µm and corresponded with a depression in the hygroscopicity of small particles. This depression can significantly suppress the number of cloud condensation nuclei thus influencing cloud properties. Results of the mini-MART collection revealed that whole bacterial inclusions are ejected into SSA via jet drops. Bacterial inclusions are rich in protein and can be identified through Principal Component Analysis (PCA) on image stacks acquired at the carbon K edge. Vesicles were not identified in SSA but could be resolved in standard liquid cell samples in which they exhibited a strong phospholipid spectrum that could also be resolved spatially usually PCA coupled with k-means clustering. Bacterial inclusions in SSA may affect SSA physical properties by serving as ice nuclei.1,2,3

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Die Veröffentlichung beinhaltet die Dissertationsarbeit 'The effect of alcohol use disorder symptom and recovery narratives on problem recognition: A randomized online trial.' Hierbei geht es um verschiedene Krankheits- und Umgangsmodelle von Alkoholabhängigkeit und wie sie die Selbsterkennung von problematischem Alkoholkonsum beeinflussen.

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