Thesis (Ph. D.)--University of Wisconsin, 1964. / Typescript. Vita. eContent provider-neutral record in process. Description based on print version record. Includes bibliographical references.

Thesis (M.S.)--University of Missouri--Columbia, 2005. / "May 2005." Typescript. Includes bibliographical references (leaves 23-27). Also issued on the Internet.

Thesis (M.S.)--University of North Texas, May, 2007. / Title from title page display. Includes bibliographical references.

The purpose of this phenomenological study was to explore the experiences of individuals who spend time in nature with their dogs. The study was guided by three key research questions: what is the essence of the experience; how does time in nature with a dog differ from time in nature without a dog; and what are the outcomes of spending time in nature with a dog? Eight participants who spent at least six hours a week in nature with their dog were interviewed. Transcripts were analyzed and coded. Three overall themes (heightened experience, negotiating constraints, and outcomes) emerged, which informed the three research questions. This study connected two related research areas, adding to existing literature on dog ownership and nature experiences. / Graduate

This study served as a preliminary investigation of the effectiveness of an understudied complementary (to traditional treatment approaches) intervention for military related PTSD. Specifically, the utilization of a nonprofit organization’s intensive three-week training program and use of psychiatric service dogs (PSDs) for PTSD and associated symptom amelioration. The sample included two separate cohorts of military veterans (n = 7 and n = 5) with prior diagnoses of PTSD. Participants completed a battery of self-report measures assessing PTSD and related symptoms, depression, perception of social support, anger, and overall quality of life. Participants also completed an attention bias task that was utilized to objectively assess changes in attentional bias to threat. Participants completed the measures one month prior to the training (baseline), at arrival to the training site, at the end of each week of the training, and at one and six month follow-up. Results indicated that, for all participants, there was a statistically significant decrease in PTSD and depression symptoms. In addition, for most participants, these decreases were both clinically significant and reliable. Further, participants reported significant reductions in anger and improvement in perceived social support and quality of life. Data from the attentional bias task was inconclusive. Limitations of the study include a lack of control group and small sample size. Despite this, the findings of this study indicate that utilizing PSDs as a complementary treatment for PTSD could yield beneficial results in terms of symptom amelioration and improvement to overall quality of life for veterans suffering from PTSD.

Orientador: Luiz Carlos Vulcano / Resumo: Os valores da densidade mineral óssea (DMO) da extremidade distal do rádio-ulna de 95 cães de diferentes portes e idades foram determinados por meio da técnica de densitometria óptica em imagens radiográficas. Para a medida da DMO foi utilizado um programa computacional que analisou a densidade óptica das radiografias confeccionadas em projeção crânio-caudal da extremidade distal do rádio-ulna e de partes moles adjacentes, juntamente com uma escala de alumínio (penetrômetro), usada como referência densitométrica, permitindo a medida da DMO do rádio-ulna, que corresponde ao valor em milímetros de alumínio da escala. Os valores da média e os desvios padrões da densidade mineral óssea da extremidade distal do rádio-ulna da amostra foram: 2,38 ± 0,70 mmAl para cães entre 01 e 10 Kg, 3,55 ± 1,04 mmAl para cães entre 10,1 e 25 Kg, e 4,69 ± 0,90 mmAl para cães com mais de 25 Kg. Ocorreu forte correlação (p<0,001) entre a DMO e o peso dos animais estudados, sendo que a DMO não foi significativamente influenciada pelo sexo e nem pela idade dos animais. / Abstract: The values of bone mineral density (BMD) of distal ext remity radius - ulna of 95 dogs of different weights and ages were determinated using the technique of optical densitometry in radiographic images. To measure BMD it was used a computer software that analyses the optical density of radiographic in craniocaudal view from the distal extremity radius - ulna and adjacent soft parts, with an aluminum scale (penetrometer), used as a densitometry reference, allowing the measurement of the radius - ulna BMD, that corresponds to the value in millimeters of the scale. The mean values and the standard deviation of bone mineral density of the extremity radius - ulna of the sample were: 2,38 ± 0,70 mmAl for dogs between 01 and 10Kg, 3,55 ± 1,04 mmAl for dogs between 10,1 and 25Kg, and 4,09 ± 0,90 mmAl for dogs over 25Kg. There was a strong correlation (p<0,001) between the BMD and the studied animals weight, although BMD was not significantly influenced by the animals sex or age. / Mestre

Orientador: Valéria Marçal Felix de Lima / Coorientador: Paulo César Ciarlini / Banca:Luiz Daniel de Barros / Banca:Flavia Lombardi Lopes / Banca:Suely Regina Mogami Bomfim / Banca; Rosimeri de Oliveira Vasconcelos / Resumo: A leishmaniose visceral canina (LVC) é uma doença crônica que causa imunossupressão nos animais doentes, principalmente por prejudicar a resposta imunológica celular, diminuindo a proliferação linfocitária e a capacidade fagocítica das células de defesa. Recentemente, a enzima heme oxigenase-1 (HO-1) vem ganhando destaque por estar envolvida na regulação da resposta imune celular em algumas condições patológicas, sendo uma enzima induzível por condições de estresse, como o estresse oxidativo que sabidamente ocorre na LVC. Nesse contexto, esse trabalho teve por objetivo determinar o papel da HO-1 na LVC, determinando sua concentração e expressão em cães infectados e saudáveis, correlacionando-a com o estresse oxidativo, carga parasitária e IL-10. Objetivou-se também avaliar o efeito da indução e inibição da enzima sobre a resposta linfoproliferativa de células de linfonodo de cães doentes e sobre a taxa de infecção macrofágica por promastigotas de Leishmania infantum, determinando as citocinas envolvidas. Os cães com LVC apresentaram marcante estresse oxidativo e aumento da concentração e expressão de HO-1, obtendo-se correlação positiva entre HO-1e estresse oxidativo e IL-10 de acordo com o tecido analisado. A inibição de HO-1 aumentou a taxa de proliferação celular na presença de antígeno solúvel de L. infantum, enquanto a indução de HO-1 diminuiu a taxa de proliferação antígeno-específica e aumentou a taxa de infecção macrofágica e o número de amastigotas por macrófago. Con... (Resumo completo, clicar acesso eletrônico abaixo) / Abstract: Canine visceral leishmaniasis (CVL) is a chronic disease that causes immunosuppression by reducing the cellular response of infected animals, impairing the cell proliferation and the phagocytic ability of defense cells. Recently, heme oxygenase-1 (HO-1) has been highlighted for being involved in regulation of cell response in certain pathological conditions, and for being an enzyme that can be induced by stress conditions, such as oxidative stress, that is known to occur in CVL. In this context, this study aimed to determine the role of HO-1 in CVL, determining its levels and expression in infected and healthy dogs, correlating these findings with oxidative stress, parasite load and IL-10. The effect of induction and inhibition of HO-1 on lymphoproliferative response by lymph node cells of infected dogs and macrophage infection rate by promastigotes of Leishmania infantum were also evaluated. Dogs with CVL showed marked oxidative stress and increased levels and expression of HO-1, obtaining a positive correlation between HO-1 and oxidative stress and IL-10 in a tissue-dependent way. Inhibition of HO-1 increased proliferation rate in the presence of L. infantum soluble antigen, while induction of HO-1 decreased antigen-specific proliferation and increased macrophage infection rate and number of amastigotes per macrophage. The increase in HO-1 metabolism observed in CVL is associated to oxidative stress present in these dogs and could be one of the mechanisms involved in the in... (Complete abstract click electronic access below) / Doutor

Orientador: Alexandre Lima de Andrade / Banca: Paola Castro Moraes / Banca: Maria Gisela Laranjeira / Resumo: O objetivo deste trabalho foi o de avaliar a cicatrização óssea de fraturas experimentais do radio de cães, tratadas ou não com o PRP autógeno, por meio de estudos radiográfico, densitométrico e histológico; bem como avaliar a expressão dos fatores de crescimento do PRP. Foram utilizados 21 cães inicialmente agrupados de acordo com o tempo de colheita de biopsia: aos sete dias (n=10) ou 60 dias (n=11) que foram alocados aleatoriamente em dois grupos experimentais: o grupo controle (G-controle, n=11) e o grupo PRP (G-PRP, n=10). Todos os animais foram submetidos à osteotomia e osteossíntese (fixador esquelético externo) do rádio direito, gerando-se um "gap" de 2,0mm, que foi preenchido ou não com PRP. Os estudos radiográficos e densitométricos foram realizados no pós-operatório imediato e até 60 dias de pós-operatório. As avaliações histológicas e imunoistoquímicas foram realizadas aos sete e 60 dias. Os dados encontrados foram tratados estatisticamente (p<0,05). Houve diferença significativa nas avaliações radiográficas e densitométricas entre os grupos. A avaliação histológica evidenciou uma cicatrização óssea mais avançada aos 60 dias no G-PRP e união óssea tardia no G-controle. Houve imunomarcação intensa do PDGF-B e TGF-β no G-PRP aos sete e 60 dias de pós-operatório. Conclui-se, que o PRP pode ser utilizado como terapia adjuvante, pois promoveu melhor cicatrização óssea em fraturas experimentais ("gap" de 2,0mm) do radio de cães tratadas com fixador esquelético externo. Ainda houve maior expressão do PDGF-B e TGF-β nos períodos, precoce e tardio, dos animais tratados com PRP / Abstract: The present article aimed to assess bone healing of experimental radial fractures, treated or not with autologous PRP, by means of radiographic, densitometric and histological studies and evaluate the expression of growth factors in PRP. Were used 21 dogs initially grouped according to the time of biopsy collection: seven days (n = 10) or 60 days (n = 11) were randomly assigned to two groups: the control group (G-control, n = 11) and the PRP group (G-PRP, n = 10). All animals underwent osteotomy and fixation (external skeletal fixation) of the right radius, generating a gap of 2.0 mm, which was filled or not with PRP. Radiographic and densitometry studies were performed in the immediate postoperative period and to 60 days after the surgery. The histological and immunohistochemical evaluations were performed at seven and 60 days. The data were treated statistically (p <0.05). There were significant differences in densitometric and radiographic evaluations between the groups. Histological evaluation showed a more advanced bone healing at 60 days in G-PRP and bone union late in the G-control. There was intense expression of PDGF-B and TGF-β in G-PRP from seven to 60 days postoperatively. It is concluded that the PRP can be used as adjuvant therapy, because it provided better bone healing in experimental fractures (gap of 2.0 mm) radius of dogs treated with external skeletal fixation. Although there was a higher expression of PDGF-B and TGF-β in periods, early and late, the animals treated with PRP / Mestre

A study was conducted to evaluate the ability of police dog teams to identify "guilty" subjects in a simulated crime situation and to compare their accuracy with that of a polygraph examination. Research on the olfactory acuity of dogs, and on the role of olfactory cues such as pheromones in social communication, implies that the detection of guilt by experienced police dogs could occur as reliably as police dog handlers believe. The literature on polygraph investigations shows high reliability in detecting guilt. This was one of the reasons for using the polygraph as the comparison technique. Three experienced dog teams from the Vancouver Police Dog Squad and two expert polygraph field examiners were used. The subjects were 64 male volunteers, all university or college students. Subjects randomly assigned to the "guilty" condition were instructed to "steal" and conceal a $10 bill that had been left in an empty office, and to deny throughout the rest of the experiment that they had done so. Volunteers in the "not guilty" condition were told nothing about the "crime" Both groups were told that police dog teams and polygraph operators would try to find out whether they were guilty. They were promised $5.00 for participating plus a bonus of $10 if they succeeded in establishing that they were innocent. Police dog team performance was about chance level, while the polygraph examination was significantly more accurate than chance and than the dog teams. No individual difference was found among the dog teams. The failure of the dog teams could be attributed either to the impossibility of detecting guilty by smell cues or to some aspect of the simulation procedure. Further research should be directed at developing more realistic field studies. / Arts, Faculty of / Psychology, Department of / Graduate

Please read the abstract in the section 00 front of this document / Dissertation (M Med Vet (Clinical Laboratory Diagnostics))--University of Pretoria, 2001. / Companion Animal Clinical Studies / unrestricted