This work deals with processing and analysis of micro-CT images of dental-canals filled by~two materials (AH-plus and NaMPC). For that reason, six dog-teeth were scanned in the X-Ray Micro CT Research Lab. The main aim was to produce an algorithm (in Matlab) that evaluates the quality of filling of dental canals (quality of filling materials). The algorithm performs the segmentation of dental canals and calculates their borders. Also, the algorithm measures the percentage contacts of filling materials with dental walls. Moreover, the algorithm provides masks of dental canals according to requirements of the commercial program VG Studio, that evaluates the porosity of filling materials. The results of percentage contacts and porosities show on not-remarkable differences of tested filling materials.

Low concentrations (1-10mg/mL) of double antibiotic paste (DAP) have demonstrated antibacterial properties in regenerative endodontics. The aim of this study was to evaluate if DAP made radiopaque (RoDAP) with barium sulfate has antibacterial effects against bacterial isolates from a mature and immature tooth with necrotic pulp. Clinical bacterial isolates were obtained from the canals of mature and immature teeth with necrotic pulps during root canal therapy or a regenerative procedure, respectively. Bacterial isolates were grown anaerobically for three weeks on 4x4mm dentin specimens prepared from extracted human teeth (n=48 per biofilm type). The dentin specimens were allocated into six groups and treated as follows: 1mg/mL RoDAP, 10mg/mL RoDAP, calcium hydroxide (UltraCal), placebo (barium sulfate in methylcellulose), no treatment, and no bacteria or treatment (sterile control). After one week of treatment the biofilm was detached and biofilm disruption assays were conducted to determine the bacterial numbers (CFUs/mL). The data was analyzed using Wilcoxon Rank Sum tests followed by pairwise comparisons. 1 and 10 mg/mL RoDAP as well as calcium hydroxide demonstrated significant antibacterial effects against the tested bacterial isolates. The placebo paste did not demonstrate any significant antibacterial effects. No significant difference in antibacterial effects was found against isolates from both mature and immature teeth regardless of the type of treatment. Both 1 and 10 mg/mL RoDAP demonstrated significant antibacterial effects against bacterial isolates from mature and immature teeth with necrotic pulps. RoDAP can be beneficial clinically since its adequate placement within the canal system can be confirmed radiographically.

The commonly used materials in endodontic treatment lack the ability to prevent microleakage, which can lead to failure of the treatment. This study aimed to evaluate the effectiveness of adding Coltosol plug in preventing coronal microleakage in endodontically treated teeth using the in vitro dye penetration method. Ten single canal plastic teeth were prepared and obturated using the SG-endodontic technique. The teeth were randomly divided into two groups, with and without Coltosol plug, and dye penetration was measured at 6 and up to 72 hours. No difference in leakage was observed after 6 and 72 hours. Specimens with a plug of Coltosol showed similar dye penetration compared to the ones with only Gutta-percha and sealer.

Syftet med denna masterstudie var att jämföra den smärtlindrande effekten av fullständig utrensning och desinfektion av rotkanalsystemet med enbart utrymning av pulpakavum, utan instrumentering av rotkanalerna, som akutbehandling hos tänder med symtomatisk apikal parodontit. Materialet utgjordes av 16 patienter insamlade på Tandvårdshögskolans jourmottagning. Patienter med svullnad och allmänpåverkan exkluderades. Patienterna valdes slumpmässigt ut till att genomgå någon av behandlingarna. Den preoperativa smärtnivån och ev. analgetikaintag registrerades. Tre till fem dagar efter utförd behandling kontaktades patienterna per telefon och fick då gradera sin postoperativa smärtnivå samt analgetika- och/eller antibiotikaintag. Resultatet visade att 100% av patienterna som behandlades med fullständig utrensning erhöll tillfredställande smärtlindring jämfört med 71% av de patienter som behandlades med enbart utrymning av pulpakavum. Skillnaden var inte statistiskt signifikant. 44% av patienterna som behandlades med fullständig utrensning hade tagit smärtstillande postoperativt medan 29% av patienterna i utrymningsgruppen hade gjort det. Skillnaden var inte signifikant. Ingen av patienterna oavsett behandling hade tagit antibiotika efter behandlingen. Ingen skillnad förelåg i andelen patienter som blev tillräckligt smärtlindrade mellan fullständig utrensning och enbart utrymning av pulpakavum hos tänder med symtomatisk apikal parodontit. Det var inte heller någon skillnad i smärtsänkning mellan de två behandlingarna. / The aim was to compare the pain relieving effect of complete chemo mechanical disinfection of the root canal system with removal of necrotic tissue in the pulp chamber without instrumentation of the root canals as emergency treatment in teeth with symptomatic apical periodontitis. The material consisted of 16 patients collected at the emergency clinic at Malmö University. Patients with swelling and/or systemic involvement were excluded. The patients were randomized to either treatment. The preoperative pain level and intake of analgesics was registered. Three till 5 days postoperatively the patients were contacted and asked to grade the current pain level and intake of analgesics and/or antibiotics. The results showed that 100% of the patients treated with complete chemo mechanical disinfection of the root canal system obtained satisfying pain relief compared to 71% for patients treated with removal of necrotic tissue in the pulp chamber. 44% of the patients treated with chemo mechanical disinfection of the root canal system had some kind of analgesics postoperatively compared to 29% for those treated with removal of necrotic tissue in the pulp chamber. No patients in either group reported use of antibiotics postoperatively. The conclusion was that both complete chemo mechanical disinfection and removal of necrotic tissue implied a significant pain relief as emergency treatment in teeth with symptomatic apical periodontitis. There was no difference between the two treatments concerning the number of patients who obtained sufficient pain relief or in pain relieving effect.

Syftet med denna randomiserade kliniska studie var att jämföra anestesieffekten mellan 2 % lidocain med 1:200,000 adrenalin och 3 % prilocain med 0,03 i.u./ml felypressin vid en blockad av Nervus alveolaris inferior för behandling av patienter med symtomatisk pulpit i en underkäksmolar eller –premolar.Materialet utgjordes av 5 patienter som uppsökt Tandvårdshögskolans jourmottagning för akuta besvär. Patienterna fick upp till 3,6 ml av antingen 2% lidocain (n=4) eller 3% prilocain (n=1). Det valda medlet var okänt för både patient och behandlare under hela behandlingen. Behandling (pulpotomi) påbörjades först när patienten erhållit bedövad läpp. Information om smärta före och under behandling, intag av analgetika och oro inför behandling noterades. Lyckad anestesi ansågs vara ingen eller endast mild smärta under behandling (<54 mm av 170 mm på en visuell analog skala).Lyckandefrekvensen för lidocain var 50 % och för prilocain 100 %. Det insamlade materialet var för litet för möjliggöra statistisk analys.De patienter som inkluderades i denna pilotstudie var för få för att visa eventuella skillnader i anestesieffekt mellan lidocain och prilocain vid en blockad av Nervus alveolaris inferior för behandling av patienter med symtomatisk pulpit i en underkäksmolar eller –premolar. Ett större underlag krävs för att kunna dra slutsatser om något av de testade bedövningsmedlen är överlägset. Ett stickprov på 57 deltagare i varje grupp krävs för att upptäcka en skillnad i lyckandefrekvens på 25 % (power 80 %). Protokollet har nu testats och visat sig vara lämpligt att använda i en större studie. / The aim of this randomized clinical trial was to compare the anesthetic efficacy of 2% lidocaine with 1:200,000 epinephrine and 3% prilocaine with 0,03 i.u./ml felypressin used for the inferior alveolar nerve block (IANB) in endodontic treatment of adult patients with symptomatic pulpitis in posterior mandibular teeth.5 patients visiting the emergency clinic of the Faculty of Odontology, Malmö University participated in the study. They randomly received, in a double-blind manner, up to 3,6 ml of either 2% lidocaine (n=4) or 3% prilocaine (n=1) in a conventional IANB. Treatment (pulpotomy) was only initiated after profound lip numbness was obtained. Pre- and perioperative pain, intake of analgesics and anxiety was recorded. Anesthetic success was defined as no or only mild pain (a rating of <54mm on a 170mm Visual Analogue Scale) during treatment.The success rate for IANB using lidocaine was 50% and for prilocaine 100%. The material size was insufficient to enable statistical analysis.The few patients selected for this pilot study were insufficient to assess any difference in anesthetic efficacy between lidocaine and prilocaine for IANB in endodontic treatment of adult patients with symptomatic pulpitis in a posterior mandibular tooth. Further data collection is needed to make conclusions about possible superiority of any of the tested substances. A sample size of 57 test subjects in each group would give a power of 80% to detect a difference of 25% in success rate. The protocol appears to be suitable for use in a larger-scale study.

Syftet med den här systematiska litteraturöversikten var att ta reda på om vitala tänder restaurerade med kompositmaterial har högre risk för att utveckla endodontiska komplikationer över tid såsom apikal parodontit eller smärta i jämförelse med tänder som restaurerats med andra dentala fyllningsmaterial som amalgam. Komposit används ofta som ett fyllningsmaterial och även om man studerat kompositers påverkan på t.ex. pulpaceller och funnit att det inte är helt oskadligt är det oklart om materialet faktiskt påverkar pulpan och leder till endodontiska komplikationer. Genomförandet av systematiska litteraturöversikten omfattade (i) formulering av frågeställning, (ii) konstruktion och genomförande av litteratursökning med (iii) tolkning och värdering av den identifierade litteraturen. Den initiala sökningen i databasen PubMed gav 938 publikationer som granskades oberoende av tre personer. Efter ytterligare sökningar kvarstod totalt tio studier som inkluderades i den systematiska litteraturöversikten. Alla inkluderade studier bedömdes ha ett lågt bevisvärde vilket ledde till att ingen konklusion med evidensgrad kunde ges. De inkluderade studierna rapporterar få, om ens några, endodontiska komplikationer och få eller inga skillnader rapporterades vid tänder restaurerade med komposit jämfört med amalgam. Fler väl genomförda studier med ett stort antal patienter krävs för att svara på frågan om tänder restaurerade med kompositmaterial har högre risk för att utveckla endodontiska komplikationer i jämförelse med andra dentala fyllningsmaterial.

El objetivo de este estudio fue comparar la capacidad de remoción de material de relleno entre sistemas de limas reciprocantes y rotatorios. Este fue un estudio in vitro, experimental, prospectivo. Para esta investigación se utilizaron 30 piezas dentarias, premolares inferiores, y se dividieron en 2 grupos de 15 cada uno respectivamente. El primer grupo fue tratado con la lima Easy ProDesign Logic RT y el segundo grupo con la lima R 50 del sistema Reciproc. Como resultado se obtuvo que al comparar la remoción del material de relleno entre los sistemas de limas reciprocantes y rotatorios hay un *P 0.197 indicando que no existe diferencia significativa entre ambos sistemas. Se llegó a la conclusión que los sistemas de limas rotatorias y reciprocantes no mostraron diferencias significativas a la remoción de material de relleno. los sistemas de limas rotatorias y reciprocantes no mostraron diferencias significativas a la remoción de material de relleno al ser comparadas en los tercios cervical, medio y apical. Las limas Easy ProDesign Logic RT lograron la remoción parcial del material en más de dos minutos.Y las lima R 50 del sistema Reciproc lograron la remoción parcial del material al 1-2 minutos en un 60%; mientras que, el 40% en 2 minutos a más. / The objective of this study was to compare the filler removal capacity between reciprocating and rotary file systems. This was a prospective, experimental, in vitro study. For this research, 30 teeth, lower premolars, were used and divided into 2 groups of 15 each respectively. The first group was treated with the Easy ProDesign Logic RT file and the second group with the R 50 file of the Reciproc system. As a result, it was obtained that when comparing the removal of the filling material between the reciprocating and rotary file systems there is a *P 0.197 indicating that there is no significant difference between both systems. It was concluded that the rotary and reciprocating file systems did not show significant differences in the removal of filling material. The rotary and reciprocating file systems did not show significant differences in the removal of filling material when compared in the cervical, middle and apical thirds. The Easy ProDesign Logic RT files achieved partial material removal in more than two minutes. And the R 50 files of the Reciproc system achieved partial material removal in 1-2 minutes by 60%; while, 40% in 2 minutes or more.

O objetivo do presente estudo foi determinar a área alargada posterior ao retratamento do canal radicular com instrumentos de níquel-titânio em imagens de tomografia computadorizada de feixe cônico. Sessenta raízes mesiais de molares inferiores foram selecionadas e submetidas a tomografia computadorizada de feixe cônico(TCFC) em 4 períodos de: antes do preparo (T1), após o preparo (T2), após o retratamento (T3) e após a complementação do retratamento (T4). Após a TCFC inicial (T1), os dentes foram submetidos ao protocolo de abertura coronária e exploração dos canais com lima manual tipo K n.15, preparados com instrumentos ProTaper Next (até X3: # 30.07), e submetidos novamente a TCFC (T2); A seguir foram obturados pela técnica híbrida de Tagger com cimento AH Plus, e submetidos a 1000 ciclos de termociclagem simulando um período de 12 meses. Subsequentemente, os espécimes foram distribuídos de acordo com os protocolos de desobturação do canal radicular, em três grupos (n=10): G1- Protaper Universal Retratamento (D1: #30.09; D2: #25.08; D3: #20.07;); G2- Mtwo Retratamento (#25.05) e G3- DRaCe (DR1: #30.10; DR2: #25.04). Após a desobturação, os espécimes foram submetidos novamente à TCFC (T3). Em seguida, foram submetidos ao protocolo de complementação para remoção do material obturador, em três grupos (n=10): G1, G2 e G3: PT next X4: #40.06. A seguir os espécimes foram submetidos novamente à TCFC (T4) para avaliação da área alargada do canal radicular. A média e o desvio padrão das variáveis quantitativas foram obtidas. A normalidade dos dados foi avaliada pelo teste de Kolmogorov-Smirnov. As variáveis foram avaliadas pelo Teste-t para amostras pareadas para avaliar a diferença entre a área desgastada entre o preparo (Tomografia 2) e o retratamento (Tomografia 4). As variáveis foram avaliadas pelo Teste de Análise de Variância (ANOVA) post hoc Tukey para a comparação entre Protaper-R (grupo 1), Mtwo-R (grupo 2) e D- Race (grupo 3). Foram considerados significativos valores de p < 0,05. A análise de variância evidenciou diferença estatisticamente significante em relação aos grupos em canal mesiovestibular em nível 2 mm abaixo de furca p<0,038 e em canal mesiovestibular em nível 4 mm abaixo de furca p<0,005. Evidenciou também diferença estatisticamente significante em relação aos grupos 1, 2 e 3 em canal mesiovestibular em nível 2 mm abaixo de furca após o retratamento p<0,028. A diferença média da área alargada entre o preparo e o retratamento em canais mesiovestibulares comparando os grupos Protaper-R, Mtwo-R e D-race evidenciou diferença estatisticamente significante em todos os grupos (p<0,000 e p<0,029) e em canais mesiolinguais valores entre p<0,000 e p<0,029. Conclui-se que as técnicas de complementação avaliadas aumentaram a área do canal radicular, contribuindo para a remoção do remanescente de material obturador, sendo que o sistema Protaper-R ® permitiu maior desgaste. Embora tenha havido ampliação da área do canal radicular em níveis determinados, nenhuma das técnicas avaliadas foram capazes de remover completamente o material obturador dos canais radiculares / The objective of the present study was to determine the enlarged area after retreatment of the root canal with nickel-titanium instruments in conical beam computed tomography images. Sixty mesial roots of mandibular molars were selected and submitted to concomitant computed tomography (CBCT) in 4 periods of: before preparation (T1), after preparation (T2), after retreatment (T3) and after completing retreatment (T4). After the initial CBCT (T1), the teeth were submitted to the protocol of coronary opening and exploration of channels with manual file type K n.15, prepared with ProTaper Next instruments (up to X3: # 30.07), and again submitted to CBCT); They were then filled by the Tagger hybrid technique with AH Plus cement and submitted to 1000 cycles of thermocycling simulating a period of 12 months. Subsequently, the specimens were distributed according to root canal clearance protocols, in three groups (n = 10): G1 Protaper Universal Retreatment (D1: # 30.09; D2: # 25.08; D3: # 20.07;); G2- Mtwo Retreatment (# 25.05) and G3- DRaCe (DR1: # 30.10; DR2: # 25.04). After disintegration, the specimens were again submitted to TCFC (T3). Afterwards, they were submitted to the complementation protocol to remove the obturator material, in three groups (n = 10): G1, G2 and G3: PT next X4: # 40.06. Afterwards the specimens were again submitted to TCFC (T4) for evaluation of the enlarged area of the root canal. The mean and standard deviation of the quantitative variables were obtained. The normality of the data was evaluated by the Kolmogorov-Smirnov test. The variables were evaluated by the t-Test for paired samples to evaluate the difference between the worn area between the preparation (Tomography 2) and the retreatment (Tomography 4). The variables were evaluated by the Tukey post-hoc ANOVA for the comparison between Protaper- R (group 1), Mtwo-R (group 2) and D-Race (group 3). Values of p <0.05 were considered significant. The analysis of variance showed a statistically significant difference in relation to the groups in mesiobuccal channel at level 2 mm below furca p <0.038 and in mesiobuccal channel at level 4 mm below furca p <0.005. There was also a statistically significant difference in relation to groups 1, 2 and 3 in mesiobuccal channel at level 2 mm below furcation after retreatment p <0.028. The mean difference in the wide area between preparation and retreatment in mesiobuccal canals comparing the Protaper-R, Mtwo-R and D-race groups showed a statistically significant difference in all groups (p <0.000 and p <0.029) and in mesiolinguistic channels values between p <0.000 and p <0.029. It was concluded that the complementation techniques evaluated increased the root canal area, contributing to the removal of the remainder of the obturator material, and the Protaper-R ® system allowed for greater wear. Although there was enlargement of the root canal area at determined levels, none of the techniques evaluated were able to completely remove the obturator material from the root canals

O desenvolvimento de cimentos endodônticos com maior capacidade antimicrobiana, leva a associação de cimentos endodônticos com agentes antimicrobianos. O vanadato de prata nanoestruturado decorado com nanopartículas de prata (AgVO3) é um nanomaterial com capacidade antimicrobiana com aplicação na odontologia. O objetivo desse trabalho foi avaliar quatro cimentos endodônticos (AH Plus, Sealapex, Sealer 26 e Endofill) incorporados com AgVO3, em diferentes concentrações (0%, 2,5%, 5% e 10%), através de testes in vitro de concentração inibitória mínima (CIM) e capacidade antimicrobiana (difusão em ágar) (n=6) frente aos micro-organismos: Enterococcus faecalis, Pseudomonas aeruginosa, Escherichia coli. Testes das propriedades físicas de escoamento (n=6), radiopacidade (n=5), teste de alteração de cor da estrutura dental (n=3) e padrão de distribuição superficial do AgVO3 aos cimentos endodônticos (n=5) foram realizados. Para análise estatística da capacidade antimicrobiana e escoamento foram realizados teste paramétrico 2-way ANOVA e teste de Tukey honestly significant difference (HSD), os dados da radiopacidade foram analisados pelo teste Kruskal-Wallis e teste de permutação com nível de significância de 5%, e para a alteração de cor realizou-se análise estatística descritiva. A CIM do AgVO3 para E. faecalis foi de 500 &micro;g/mL e para P. aeruginosa e E. coli de 31,25 &micro;g/mL. A incorporação de 10% de AgVO3 promoveu maior atividade antimicrobiana a todos os cimentos frente a E. coli, ao Sealer 26 e Sealapex frente a E. faecalis e ao AH Plus e Endofill frente a P. aeruginosa (p<0,05). A incorporação de AgVO3 não influenciou na atividade antimicrobiana inerente do AH Plus frente a E. faecalis (p>0,05) e não promoveu tal propriedade ao Sealer 26 e Sealapex frente a P. aeruginosa (p>0,05). O escoamento do AH Plus e Endofill reduziu com o aumento da concentração de AgVO3 (p<0,05). Não houve influência no escoamento do Sealer 26 e Sealapex (p>0,05). Todos os grupos apresentaram valores de escoamento dentro do recomendado pela American National Standard/American Dental Association (ANSI/ADA), exceto o AH Plus 10%. O AgVO3 não influenciou na radiopacidade do Endofill (p=0,399) e Sealapex (p=0,316), e a concentração de 2,5% do Sealer 26 e AH Plus apresentou maior radiopacidade em relação ao controle (p=0,022 e p=0,006, respectivamente), que não diferiu dos demais grupos (p>0,05). Todos cimentos incorporados com AgVO3 apresentaram maiores alterações de cor após 180 dias, a menor alteração foi do Endofill 10% e a maior do Sealer 26 10%. O AgVO3 apresentou um padrão de distribuição superficial circular na composição dos cimentos endodônticos. Concluiu-se que a incorporação do AgVO3 tem potencial para aumentar a atividade antimicrobiana dos cimentos endodônticos avaliados, não influenciou no escoamento do Sealer 26 e Sealapex, e na radiopacidade dos cimentos avaliados. Os grupos incorporados com AgVO3 apresentaram maior alteração de cor com 180 dias, exceto o Endofill 10%. / The development of endodontic sealers with higher antimicrobial capacity, leads to the association of endodontic sealers with antimicrobial agents. The nanostructured silver vanadate decorated with silver nanoparticles (AgVO3) is an antimicrobial nanomaterial with application in dentistry. The aim of this study was to evaluate four endodontic sealers (AH Plus, Sealapex, Sealer 26 and Endofill) incorporated with AgVO3, in different concentrations (0%, 2.5%, 5% and 10%), through in vitro tests of minimum inhibitory concentration (MIC) and antimicrobial capacity (agar diffusion method) (n=6) against microorganisms: Enterococcus faecalis, Pseudomonas aeruginosa, Escherichia coli. Tests on physical properties of flow (n = 6), radiopacity (n = 5), tooth discoloration (n = 3) and superficial distribution pattern of the AgVO3 to endodontic sealers (n = 5) were performed. For statistical analysis of antimicrobial capacity and flow, were performed the 2-way ANOVA parametric test and the Tukey honestly significant difference (HSD) test, the radiopacity data were analyzed by the Kruskal-Wallis test and permutation test with significance level of 5%, and descriptive statistical analysis was performed for tooth discoloration. The MIC of AgVO3 for E. faecalis was 500 &micro;g/mL and for P. aeruginosa and E. coli 31,25 &micro;g/mL. The incorporation of 10% of AgVO3 increased antimicrobial activity to all sealers against E. coli, to Sealer 26 and Sealapex against E. faecalis and to AH Plus and Endofill against P. aeruginosa (p <0.05). The incorporation of AgVO3 did not influence on antimicrobial activity inherent of the AH Plus against E. faecalis (p> 0.05) and did not promote this property to Sealer 26 and Sealapex against P. aeruginosa (p> 0.05). The flow of AH Plus and Endofill decreased with increasing AgVO3 concentration (p <0.05). There was no influence on the flow of Sealer 26 and Sealapex (p> 0.05). The evaluated groups presented flow values within the recommended by the American National Standard/American Dental Association (ASNI/ADA), except the AH Plus 10%. The AgVO3 did not influence the radiopacity of Endofill (p = 0.399) and Sealapex (p = 0.316), the concentration of 2.5% of Sealer 26 and AH Plus presented higher radiopacity than the control (p = 0.022 and p = 0.006, respectively), which did not differ from the other groups (p> 0.05). All sealers incorporated with AgVO3 presented color alterations after 180 days, the lowest change was Endofill 10% and the highest was Sealer 26 10%. The AgVO3 presented a pattern of circular superficial distribution in the composition of the endodontic sealers. It is concluded that the incorporation of AgVO3 has the potential to increase the antimicrobial activity of the endodontic sealers evaluated, did not influence the flow of the Sealer 26 and Sealapex, and the radiopacity of sealers evaluated. The groups incorporated with AgVO3 presented color alterations with 180 days, except Endofill 10%.

No modelo tradicional de ensino, desenvolver os aspectos cognitivos, psicomotores e comportamentais inerentes ao diagnóstico e plano de tratamento em Endodontia, tornam-se um problema, devido ao número relativamente limitado de experiências clínicas vivenciadas pelos alunos na formulação do diagnóstico, bem como a disponibilidade do professor compatível ao número de alunos na clínica endodôntica e o número cada vez mais insuficiente de pacientes para atender a demanda. Neste sentido, o desenvolvimento de estratégias de ensino-aprendizagem eficientes e de avaliação das competências relacionadas ao diagnóstico, seria interessante para a educação em Endodontia. O objetivo deste trabalho foi verificar e comparar o desempenho de alunos de Endodontia, tendo como fonte de variação para a metodologia educacional, a utilização da tecnologia hipermídia e o uso da internet como facilitadores do processo de ensino-aprendizagem. Para isso, graduandos do terceiro ano de Odontologia de três Universidades foram divididos em três grupos, de acordo com a metodologia de ensino-aprendizagem utilizada: GI método tradicional centrado no professor - grupo controle (n = 23); GII método tradicional acrescendo uma revisão centrada no professor, antes da avaliação (n = 30) e, GIII método de auto-instrução centrado no aluno utilizando a tecnologia hipermídia com acesso através da internet (n = 90). O site endo-e.com foi utilizado como método de auto-instrução, incluindo, entre outros temas, as doenças da polpa e do periápice, diagnóstico e tratamento endodôntico, além da simulação de casos clínicos com todas as modalidades das doenças da polpa e do periápice, tanto para treinamento, bem como para avaliação dos alunos. Os resultados obtidos na avaliação foram submetidos à análise estatística, por meio dos testes Kruskal-Wallis e Student Newman Keuls. A estratégia centrada no professor com revisão, onde os alunos interagiram com situações simuladas após as aulas teóricas tradicionais, foi o método mais eficiente, apresentando resultados estatisticamente significantes (p<0,01), em relação às demais estratégias utilizadas. Não foram observadas diferenças estatísticas significantes entre os grupos que utilizaram estratégias centradas exclusivamente no professor e no aluno, ambas sem o uso da revisão interativa. A tecnologia hipermídia e o uso da internet quando empregados isoladamente, sem despender nenhuma hora/aula presencial, mostrou equivalência com a estratégia de ensino-aprendizagem convencional centrada no professor, podendo ser considerada como estratégia complementar ou facilitadora da aprendizagem do diagnóstico em Endodontia. / In the traditional education model, developing of cognitive learning, psychomotor and conduct aspects during the endodontic diagnosis and treatment planning become a problem for students due to the relatively limited number of clinical experiences in diagnosis as well as the availability of adequate teacher/student ratio and the insufficient number of patients. Thus, the development of new strategies for effective teaching and learning process and evaluations in diagnosis would be interesting for education in Endodontics. The aim of this study was verified and compares the students performance in Endodontic varying the educational methodology where the use of hypermedia technology and internet could make the teaching-learning process easier. For this, undergraduate dental students from three universities were divided in three groups according to the applied teaching-learning methodology: GI - Traditional centered teacher - control group (n=23), GII Adding a review before the traditional centered teacher method (n = 30) and GIII - Self-instruction using hypermedia technology accessed by Internet (n = 90). The www.endo-e.com website was used as a self-instruction and evaluation method that includes diagnosis of pulp and periapical diseases, root canal therapy and clinical cases simulation. The results were statistically analyzed using Kruskal-Wallis followed by Student-Newman-Keuls tests. The strategy focused on the teacher that used previous review, where students interacted with simulated conditions following traditional class was the most efficient method and showed statistically significant difference (p<0,01) when compared with other strategies. There were no statistically significant differences between groups using strategies focused just on the teacher and student without the use of interactivity. Hypermedia technology and the use of Internet showed equivalence with the conventional teaching and learning strategy (teacher-centered) and can be considered as a complementary strategy to facilitate the diagnosis learning in Endodontics.