Neste trabalho, estudamos alguns colóides magnéticos dos tipos iônico e surfactado com partículas de estrutura tipo espinélio. Usamos a técnica de varredura-Z para investigar as amostras nas escalas de tempo de femtossegundos e milissegundos. Medimos o índice de refração não-linear nas duas escalas de tempo. Na escala de milissegundos todas as amostras apresentaram comportamento tipo lente divergente, e os valores obtidos são da ordem de 10^(-7) cm^2/W. Na escala de femtossegundos, as amostras iônicas apresentaram comportamento tipo lente convergente, com valores típicos do índice de refração não-linear da ordem de 10^(11) cm^2/W. Também medimos a absorção não-linear na escala de tempo de femtossegundos. Os valores obtidos são da ordem de 10^2 cm/GW. Com os dados obtidos na escala de femtossegundos calculamos a susceptibilidade elétrica de terceira ordem (chi(3)). O módulo de chi(3) encontrado é da ordem de 10^(-17) m^2/V^2 (ou 10^(-9) esu). Obtivemos evidências experimentais da contribuição da susceptibilidade elétrica de quinta-ordem nas medidas de absorção não-linear. Verificamos a presença do efeito de tamanho das partículas no valor de chi(3) ao estudar partículas de mesma composição e de diâmetros diferentes. / In this work, we studied some magnetic colloids of kind ionic and surfacted with particles of spinel struture. We used the Z-Scan technique to investigate the samples in the time scales of femto- and milliseconds. We measured the nonlinear refractive index in both time scales. In the scale of milliseconds all samples showed divergent-lens-type behavior, and the obtained values are of order of 10^(-7) cm^2/W. In the femtoseconds scale, the ionic-type samples have convergent-lens-type behavior, with the typical values of order of 10^(11) cm^2/W. Also we measured the nonlinear absorption in the femtoseconds time scale. The obtained values are of order of 10^2 cm/GW. With the data obtained in the femtoseconds time scale we calculated the third-order electric susceptibilities (chi(3)). The found modulus of chi(3) is of order of 10^(-17) m^2/V^2 (or 10^(-9) esu). We obtained experimental evidences that fifth-order electric susceptibilities can contribute to the measurements of nonlinear absorption. We observed the dependence of particles\' size effect in the values of chi(3) in the studies of particles of the same composition and different diameters.

Neste trabalho, estudamos alguns colóides magnéticos dos tipos iônico e surfactado com partículas de estrutura tipo espinélio. Usamos a técnica de varredura-Z para investigar as amostras nas escalas de tempo de femtossegundos e milissegundos. Medimos o índice de refração não-linear nas duas escalas de tempo. Na escala de milissegundos todas as amostras apresentaram comportamento tipo lente divergente, e os valores obtidos são da ordem de 10^(-7) cm^2/W. Na escala de femtossegundos, as amostras iônicas apresentaram comportamento tipo lente convergente, com valores típicos do índice de refração não-linear da ordem de 10^(11) cm^2/W. Também medimos a absorção não-linear na escala de tempo de femtossegundos. Os valores obtidos são da ordem de 10^2 cm/GW. Com os dados obtidos na escala de femtossegundos calculamos a susceptibilidade elétrica de terceira ordem (chi(3)). O módulo de chi(3) encontrado é da ordem de 10^(-17) m^2/V^2 (ou 10^(-9) esu). Obtivemos evidências experimentais da contribuição da susceptibilidade elétrica de quinta-ordem nas medidas de absorção não-linear. Verificamos a presença do efeito de tamanho das partículas no valor de chi(3) ao estudar partículas de mesma composição e de diâmetros diferentes. / In this work, we studied some magnetic colloids of kind ionic and surfacted with particles of spinel struture. We used the Z-Scan technique to investigate the samples in the time scales of femto- and milliseconds. We measured the nonlinear refractive index in both time scales. In the scale of milliseconds all samples showed divergent-lens-type behavior, and the obtained values are of order of 10^(-7) cm^2/W. In the femtoseconds scale, the ionic-type samples have convergent-lens-type behavior, with the typical values of order of 10^(11) cm^2/W. Also we measured the nonlinear absorption in the femtoseconds time scale. The obtained values are of order of 10^2 cm/GW. With the data obtained in the femtoseconds time scale we calculated the third-order electric susceptibilities (chi(3)). The found modulus of chi(3) is of order of 10^(-17) m^2/V^2 (or 10^(-9) esu). We obtained experimental evidences that fifth-order electric susceptibilities can contribute to the measurements of nonlinear absorption. We observed the dependence of particles\' size effect in the values of chi(3) in the studies of particles of the same composition and different diameters.

Cette thèse a pour objectif l’étude du comportement vibratoire des suspensions à joint de ferrofluide utilisées dans un nouveau type de haut-parleur. Le moteur de ce haut-parleur, conçu pour réduire les non-linéarités d’origine magnétique, permet l’utilisation de joints de ferrofluide comme alternative aux suspensions viscoélastiques traditionnelles : sous la forme de deux joints annulaires, ils réalisent la liaison entre la partie fixe et la partie mobile du système. L’originalité du travail présenté a trait aux forts niveaux du champ magnétique présent dans le haut-parleur et à la caractérisation en dynamique des joints en terme de masse, raideur et amortissement. La première partie est une analyse expérimentale de la raideur radiale statique d’un joint au sein d’un moteur magnétique. La connaissance de cette raideur est nécessaire pour dimensionner le guidage de l’équipage mobile. Elle est étudiée en fonction du volume et de la saturation magnétique du ferrofluide. Les résultats sont en bon accord avec les simulations. Dans une deuxième partie, nous présentons une étude expérimentale sur le comportement visqueux des ferrofluides en condition de cisaillement oscillatoire et sous champ magnétique homogène et stationnaire. Cette étude s’élargie dans la suite aux conditions magnétiques du moteur, où le champ n’est plus homogène. Les propriétés sont étudiées en fonction du volume, de la viscosité et de la saturation magnétique. Un modèle pour les pertes du haut-parleur est proposé en fonction des propriétés magnétovisqueuses du ferrofluide. / The aim of this thesis is the study of the vibratory behavior of ferrofluid seals suspensions used in a new type of loudspeaker. The motor of this loudspeaker has been designed to reduce magnetic nonlinearities and allows ferrofluid seals, as two annular seals, to be used as an alternative to classical viscoelastic suspensions. Seals serve as a link between mobile to fixed part of the system. The originality of this configuration is the presence of high level magnetic field in the loudspeaker, which require a dynamic characterization of seals in term of mass, stiffness and damping. First part of this thesis is an experimental analysis of static radial stiffness of one seal inside a magnetic engine. This parameter is necessary for centering the moving part. The influence of the volume and saturation magnetization of the ferrofluid are analyzed. There is a good agreement between experimental results and simulations. In the second part, an experimental study of the viscous ferrofluid behavior under an oscillatory shear excitation and homogeneous and stationary magnetic field is presented. It is then broaden to real non homogeneous loudspeaker motor conditions. The influence of ferrofluid seals volume, viscosity and saturation magnetization are analyzed. A model which depends on the magnetoviscous properties of the ferrofluid is suggested for the loudspeaker internal losses.

<div> <div> <div> <p>Microfluidics is a new and emerging field that has applications in a myriad of microfluidic industrial applications such as biochemical engineering, analytical processing, biomedical engineering and separation of cells. Microfluidics operations are carried out in microfluidic chips, and the traditional method of fabrication is carried out in a cleanroom. However, this fabrication method is very costly and also requires professional trained personnel. In this thesis, a low-cost fabrication platform was developed based on soft-lithography technique developed to fabricate the microfluidic devices with resolution at microscale. This fabrication method is advantageous and novel because it is able to achieve the microscale fabrication capability with simple steps and lower-level laboratory configuration. In the developed fabrication platform, an array of ultraviolet light was illuminated onto a photoresist film that has a negative photomask with a microfluidic design on it. The photoresist film is then developed, and a silicon polymer of polydimethylsiloxane (PDMS) is chosen to be the material for the device. In this work, the performance and resolution of the fabrication system was evaluated using scanning electron microscopy (SEM), polymer resolution test and light intensity analysis. </p> <p>Based on the success of the development of microfluidics fabrication platform, various experiment of mixing and separation was conducted and studied because the utilization of the microfluidic device for mixing and separation is very valuable in biomedical and chemical engineering. Although there are a lot of applications reported, the precise separation and mixing at microscale still meet some difficulties. Mixing in micromixers is extremely time-consuming and requires very long microchannels due to laminar flow and low Reynolds number. Particle separation is also hard to be achieved because the size of micron bioparticles is very small and thus the force is not strong enough to manipulate their motion. The integration of magnetic field is an active method to strengthen both mixing and separation that has been widely applied in the biomedical industry overcome these difficulties because of its compatibility with organic particles. However, most magnetic mixing and separation use bulky permanent magnets that leave a large footprint or electromagnets that generate harmful Joule heat to organic and bio-particles. In this work, microscale magnet made of a mixture of neodymium powder and polydimethylsiloxane was developed and integrated into microfluidic system to achieve both rapid mixing of ferrofluids and separation of microparticles. Systematic experiments were conducted to discuss the effect of various parameters on the performance of magnetic mixing and separation of microparticles. It was found that channel geometry, flow filed, and magnetic properties will affect the transport phenomena of ferrofluid and microparticles, and thus mixing and separation efficiency. These findings are of great significance for the high throughput sorting of cancer cells and its mixing between drug for therapy treatment.</p></div></div></div>

In this study, the magnetically-induced vibrations of functionalized magnetic particle suspensions were probed for the development of a novel optical spectroscopy technique. Through this work (1) the frequency-dependence of the faraday rotation in ferrofluids and (2) the extension of this system to elucidating particle size and conformation as an alternative immunossay to costly and labor/time intensive Western Blotting and ELISA has been shown. With its sensitivity and specificity, this method has proven to be a promising multi-functional tool in biosensing, diagnostic, and therapeutic nanomedicine efforts. Due to its ubiquitous nature in all optically-transparent materials, the farady rotation, or circular birefringence, was developed as a robust and sensitive nanoscale biomolecule characterization technique through Brownian relaxation studies of particle suspensions. Current efforts have shown the applicability of this phenomenon in solid, pure liquid, and colloidal samples as well as simultaneous advancements of magnetic nanoparticle research in the magnetometric and magneto-optical regimes. By merging these two fields, a clinically relevant spectroscopy (fd-FRS, Frequency Domain Faraday Rotation Spectroscopy) was developed based on a newly revised model stemming from Debye relazation theory. Through this work, an optical bench with a variable permeability core electromagnet and a frequency-domain lock-in amplifier setup (DC to 20 kHz) have been used to distinguish between Fe3O4-core nanoparticles with functionalization layers of PEG4/PEG8 polymer with future applications involving the Anti-BSA/BSA antibody/antigen couple. Particle concentrations down to 500 nM (magnetic nanoparticles) and 0.01 Volume % (magnetic beads) were studied with diameters ranging from 200 nm to 1μm. currently, the characteristic peak corresponding to the out-of-phase relazation of the suspended particles has been elusive, despite a wide particle size distribution and the use of a balanced photodetector. Future work will involved highly monodisperse samples, faster scan times, and thermal characterization applications of fs-FRS.

Micro- or nanometer sized magnetic particles (beads) currently have a vast range of life science applications in, for example, bioseparation techniques, cancer therapy, development of contrast agents and biosensing techniques. In the latter field, magnetic beads offer several unique advantages, including minimal background signals, physical and chemical stability and low manufacturing costs. Because of these properties, magnetic biosensing techniques are potential candidates for low-cost, easy-to-use molecular diagnostic devices. This doctoral thesis focuses mainly on the proof of principle and further development of a new magnetic biosensor platform for detection of DNA targets, a potential candidate for a new generation of low-cost, easy-to-use diagnostic devices: the Volume-Amplified Magnetic Nanobead Detection Assay (VAM-NDA). The VAM-NDA principle combines target recognition by padlock probe ligation followed by rolling circle amplification (RCA) of the reacted probes with changes in Brownian relaxation behaviour of magnetic nanobeads (typically ~100 nm in diameter) induced by a change in hydrodynamic bead volume. More specifically, the RCA products (coils, typically ~1 μm in diameter) are detected magnetically by adding magnetic beads tagged with detection probes complementary to part of the repeating RCA-coil sequence. Thus, depending on the target concentration, a certain quantity of beads binds to the coils by base-pair hybridisation (bead immobilisation), resulting in a dramatic bead volume increase, which is then detected by measuring the complex magnetisation spectrum. Use of a commercial SQUID magnetometer for measuring complex magnetisation resulted in a detection limit in the low pM range for DNA targets with excellent quantification accuracy. Simultaneous multiplexing was also evaluated. The stability and aging of typical commercial ferrofluids (suspensions of magnetic beads) were investigated by measuring the complex magnetisation of and interbead interactions in oligonucleotide-functionalised ferrofluids. In summary, the bead surface characteristics were found to have a strong impact on the measured dynamic magnetic properties.

Cette thèse a étudié de façon systématique les processus de la rupture et de la coalescence impliquant une interface liquide-liquide (gouttelettes) ou gaz-liquide (bulles) en présence ou pas d’un champ magnétique dans des dispositifs microfluidiques, à l’aide d’une caméra rapide. Les mécanismes de la rupture d’une interface ferrofluide sous différents champs magnétiques ont été étudiés et comparés. On a constaté que la structure morphologique et la vitesse d’amincissement du cou peuvent être contrôlées activement par la force magnétique. Ainsi, le volume et la fréquence de formation de gouttelettes de ferrofluide peuvent être pilotés aisément. La rupture de l'interface liquide-liquide a généralement conduit à la formation de gouttelettes satellites avec sa taille proportionnelle au nombre capillaire de la phase continue. La coalescence des gouttelettes ont aussi été étudiée avec l’analyse de l'évolution du cou reliant deux gouttelettes. Il a été constaté que la formation du pont ou du cou liquide pouvait se produire dans la gamme de l'ordre de dizaines de micromètres entre les bords d'attaque sous champ magnétique. L'inertie d’origine d'attraction magnétique sur des gouttelettes de ferrofluide devenait la force motrice pour la coalescence lors de la première étape au détriment de la force capillaire / This thesis systematically investigates the breakup and coalescence processes of the involved droplet (bubble) interface under magnetic field or not in two-phase microfluidic flow, by using a high speed digital camera. The whole breakup processes of ferrofluid interface under different magnetic fields were investigated and compared. It was found that the morphological structure and necking velocity of the interface can be actively controlled by the magnetic force. Thus the volumes and the formation frequencies of ferrofluid droplets can be actively adjusted. The breakup of Liquid-Liquid interface usually leads to the formation of satellite droplet with its size proportional to the capillary number of the continuous phase. The coalescences of droplets were investigated. The evolution of the neck connecting two droplets was analyzed. It was found that the formation of liquid bridge or neck could occurs with a visible gap in the order of tens of micrometers between the leading edges under magnetic field and the inertia of the ferrofluid originating from the magnetic attraction fields becomes the driving force at the initial stage of coalescence instead of capillary force

Nous proposons d'exploiter la convection thermomagnétique, phénomène caractéristique des Ferro fluides, pour améliorer les transferts de chaleur dans les transformateurs. Les équations régissant le système se composent des équations de Navier-Stokes dans l'approximation de Boussinesq, de l'équation de la conservation de l'énergie et des équations de la magnétostatique. Les simulations sont menées avec notre code de recherche parallélisé SFEMaNS (Spectral/Finite Element for Maxwell and Navier-Stokes) pour des géométries axisymétriques, utilisant une décomposition spectrale dans la direction azimutale et des éléments finis de Lagrange dans le plan méridien. Afin de résoudre ce problème spécifique, divers développements sont apportés à SFEMaNS, tels que l'implémentation des forces magnétiques de Kelvin et de Helmholtz. Le code est d'abord appliqué au refroidissement d'un solénoïde dans une cuve cylindrique contenant de l'huile de transformateur ou un ferrofluide à base d'huile de transformateur. Les résultats montrent que l'utilisation du ferrofluide diminue la température maximale du système grâce à la convection thermomagnétique et au changement des propriétés thermophysiques du fluide. L'influence de différents paramètres (fraction volumique de nanoparticules, présence d'un cœur ferromagnétique, propriétés magnétiques des nanoparticules) est étudiée. En particulier, les simulations confirment l'intérêt des nanoparticules magnétiques à faible température de Curie. Nous montrons également sur cet exemple que deux densités de force magnétique égales à un gradient près, telles que les forces de Kelvin et de Helmholtz, donnent le même écoulement. Un bon accord qualitatif est trouvé entre les résultats numériques et expérimentaux utilisant de l'huile de transformateur ou du ferrofluide. Le code est ensuite appliqué au refroidissement d'un système proche d'un transformateur de 40 kVA (20 kV/400 V). Les résultats montrent à nouveau une réduction de la température maximale grâce au ferrofluide. / We propose to make use of thermomagnetic convection, a characteristic phenomenon of ferrofluids, to improve heat transfer in transformers. The governing equations consist in the Navier-Stokes equations under the Boussinesq approximation, the energy conservation equation and the magnetostatics equations. The simulations are performed with the in-house parallel code SFEMaNS (Spectral/Finite Element for Maxwell and Navier-Stokes) for axisymmetric geometries, using a spectral decomposition in the azimuthal direction and Lagrange finite elements in the meridian plane. In order to solve this specific problem, various developments are brought to SFEMaNS, such as the implementation of the Kelvin and Helmholtz magnetic forces. The code is first applied to the cooling of a coil in a cylindrical tank containing either transformer oil or transformer oil-based ferrofluid. The results show that the use of the ferrofluid reduces the maximum temperature in the system due to thermomagnetic convection and the change of the fluid thermophysical properties. The influence of different parameters (volume fraction of nanoparticles, presence of a ferromagnetic core, nanoparticle magnetic properties) is investigated. In particular, the simulations confirm the benefit of magnetic nanoparticles with a low Curie temperature. We also show on this example that two magnetic body forces equal up to a gradient, such as the Kelvin and Helmholtz forces, give the same flow. A good qualitative agreement is found between the numerical and experimental results using transformer oil or ferrofluid. The code is then applied to the cooling of an electromagnetic system close to a 40 kVA (20 kV/400 V) transformer. The results show again a reduction of the maximum temperature when using ferrofluid.

В работе изучается динамическая восприимчивость феррожидкости, которая моделируется системой взаимодействующих подвижных магнитных частиц. Предполагается, что система находится в постоянном и переменном магнитном полях, направленных параллельно друг другу. / In this work, we study the dynamic susceptibility of a ferrofluid, which is modeled by an system of interacting moving magnetic particles. It is assumed that the system is in a constant and an alternating magnetic field, directed parallel to each other.

Les liquides complexes sont des matériaux très prometteurs pour réaliser la conversion bon marché et à grande échelle d’énergie thermique en énergie électrique, dans un contexte de réchauffement climatique et de maîtrise de la consommation d’énergie. Nous montrons qu’en présence d’un couple redox, les cellules thermogalvaniques à base de liquides ioniques (NEA et EMIMTFSI) présentent des propriétés remarquables tels des coefficients Seebeck de plus de 5 mV/K (Eu³⁺/Eu²⁺ dans l’EMIMTFSI). De même, ces travaux présentent l’utilisation de ferrofluides, solutions colloïdales (aqueuses ou à base de solvants organiques) de nanoparticules magnétiques (maghémite), pour accroître le coefficient Seebeck et le courant extractible de générateurs thermoélectriques liquides. Les phénomènes réversibles d’adsorption des nanoparticules sur la surface des électrodes jouent également un rôle important sur les propriétés thermoélectriques de ces solutions, et sont modifiés par l’application de champs magnétiques homogènes parallèles ou perpendiculaires au gradient de température.En l’absence d’un couple redox, les liquides ioniques peuvent être utilisés pour fabriquer des supercondensateurs à charge thermique. Ces derniers exploitent les modifications avec la température des double couches électriques aux interfaces liquide/électrode. Nous avons étudié ici ces modifications de double couches dans l’EMIMBF4 par simulations numériques de Monte-Carlo. Les résultats démontrent un accroissement conséquent des propriétés thermoélectriques lors de la dilution du liquide ionique dans un solvant organique, l’acétonitrile, en accord qualitatif avec les résultats expérimentaux. / Complex liquids are promising material for low cost and wide scale conversion of thermal energy to electric energy, within a context of global warming and control of the energy consumption.In this work we showed that with a redox couple, ionic liquid (EAN and EMIMTFSI) based thermogalvanic cells present remarkable thermoelectric properties such as the Seebeck coefficient over 5 mV/K (Eu³⁺/Eu²⁺ in EMIMTFSI). Moreover, we demonstrated for the first time that ferrofluids, colloidal solutions (aqueous or organic solvent based) of magnetic nanoparticles (maghemite), can be used to increase both the Seebeck coefficient and the electric current in liquid thermoelectric generators through unknown physical processes. The importance of reversible adsorption phenomena of the nanoparticles on the electrodes’ surface for the thermoelectric properties of these solutions was revealed. That can be further modified by a homogeneous magnetic field applied perpendicular or parallel to the temperature gradient. Without a redox couple, ionic liquids can be used to build thermally chargeable supercapacitors. They take advantage of temperature dependent electrical double-layer formation at liquid/electrode interfaces. Here, we studied these double-layer modifications in EMIMBF4/platinum through Monte-Carlo simulations. The results show substantial modifications in the thermoelectric properties when the ionic liquid is diluted in an organic solvent, acetonitrile. These results are qualitatively consistent with experimental measurements.