Le système nerveux central est la cible la plus probable d'effets biologiques dûs à l'exposition aux radiofréquences (RF) de la téléphonie mobile. Plusieurs études sur l’EEG (électroencéphalogramme) ont montré des variations dans le spectre de la bande alpha pendant et / ou après l'exposition aux radiofréquences, avec les yeux fermés ou pendant le sommeil. Dans ce contexte, l'observation de l'activité électrique spontanée des réseaux neuronaux sous exposition aux radiofréquences représente un outil efficace pour détecter de possibles effets des RF de faible niveau sur le système nerveux. Dans ce travail de thèse, nous avons développé un dispositif expérimental dédié à l'exposition dans la gamme des GHz de réseaux neuronaux et permettant simultanément l’enregistrement de l'activité électrique des neurones. Une cellule électromagnétique transversale (TEM) a été utilisée afin d'exposer les réseaux neuronaux aux signaux GSM-1800 à un niveau de DAS de 3,2 W / kg. L'enregistrement de l'activité électrique neuronale et la détection en termes de spikes et bursts sous exposition ont été réalisées à l'aide de réseaux de micro-électrodes (MEAs). Ce travail démontre la faisabilité de l’étude (culture de réseaux de neurones primaires, enregistrement de l'activité électrique et analyse des signaux obtenus sous exposition aux radiofréquences) et expose des résultats préliminaires. Dans l'expérience principale (16 cultures), il y avait une diminution réversible de 30% du taux moyen de spikes (MFR) et de bursts (BR) pendant les 3 min d’exposition aux RF. Des expériences supplémentaires sont nécessaires pour mieux caractériser cet effet, notamment en termes d'élévation de la température au niveau microscopique. / The central nervous system is the most likely target of mobile telephony radiofrequency field (RF) exposure in terms of biological effects. Several EEG (electroencephalography) studies have reported variations in the alpha-band power spectrum during and/or after RF exposure, in resting EEG and during sleep. In this context, the observation of the spontaneous electrical activity of neuronal networks under RF exposure can be an efficient tool to detect the occurrence of low-level RF effects on the nervous system. In this thesis research work we developed a dedicated experimental setup in the GHz range for the simultaneous exposure of neuronal networks and monitoring of electrical activity. A transverse electromagnetic (TEM) cell was used to expose the neuronal networks to GSM-1800 signals at a SAR level of 3.2 W/kg. Recording of the neuronal electrical activity and detection of the extracellular spikes and bursts under exposure were performed using Micro Electrode Arrays (MEAs). This work provides the proof of feasibility and preliminary results of the integrated investigation regarding exposure setup, culture of the neuronal network, recording of the electrical activity and analysis of the signals obtained under RF exposure. In the main experiment (16 cultures), there was a 30% reversible decrease in mean firing rate (MFR) and bursting rate (BR) during the 3 min exposures to RF. Additional experiments are needed to further characterize this effect, especially in terms of temperature elevation at the microscopic level.

Fundação de Amparo a Pesquisa no Estado do Rio Grande do Sul / Photovoltaic solar energy (PV) grows exponentially, since 2012 reaching levels of over 100 GWp installed worldwide. In this area the Brazilian industry just awakened through auctions, mainly aimed to Distributed Generation (DG). There are few large systems (1 MWp) of PV in an urban environment. Even though, since 2012, with the ANEEL's Normative Resolution 482 there was available law, these systems weren't economically feasible until 2014. This panorama, generates methodological opportunity to PV proposition to mapping potentials in public and city buildings; targeting creation of support policies, strategies and decision makers for solar energy investments in long terms and another consequences of management. It complements the stagnation gap at Brazilian Electric System (BES) as its business models of energy contracting from its captive environment, which has shown to be very innovative for PV at leading markets such as the USA. So, this study asks whether the Net Metering is sufficient, conducting comprehensive survey of Technical and Economic Feasibility for a case study to an utility company and an university (public sector) using PV at DG. The proposal sets 10% penetration targets in the utility and measuring its consequence impacts. It predicts 5 MWp as ideal project due to restrictions, 11.3 MWp to optimize the Net Metering system and 17 MWp to turn the University into a "Net Zero Building" (or zero costs electricity bill). / A energia solar fotovoltaica (PV) cresce exponencialmente e desde 2012 atinge patamares de mais de 100 GWp mundiais instalados. Neste aspecto que envolve a geração distribuída de energia elétrica através de PV, o Brasil recentemente despertou através dos leilões. Entretanto, poucos são os sistemas de grande porte (1 MWp) de PV em ambiente urbano. Apesar de que, desde 2012, com a Resolução Normativa 482 da ANEEL já exista legislação, tais sistemas eram economicamente inviáveis até 2014. Este panorama gera oportunidades de proposição metodológica para mapeamento de potenciais de PV em órgãos públicos e cidades; visando principalmente subsidiar políticas, estratégias e apoio a decisões para investimentos de energia solar em longo prazo e demais consequências da modelagem. Esta dissertação complementa a lacuna de estagnação do Sistema Elétrico Brasileiro (SEB) quanto aos modelos de negócios dos ambientes de contratação de energia renovável, que vêm sendo inovadores para a PV em países líderes do mercado como os EUA. Este estudo questiona se o Net Metering é um mecanismo suficiente, através de um levantamento abrangente de Viabilidade Técnico-Econômica aplicada em um estudo de caso. Este considera a concessionária local e universidade (órgão público) utilizando PV como GD. Apresentam-se metas de 10% de penetração na distribuidora e identificam-se alguns impactos. Propõe-se 5 MWp como ideal devido às restrições, 11,3 MWp para otimização do Net Metering e 17 MWp para tornar a Universidade Net Zero Building (ou zero de conta de luz ).

The theoretical part of this thesis explains the process of real estate project financing, describes its main features, characterizes participants of the process and main forms of project loans. It also depicts the feasibility study as a key source of project bank loan application, describe collection of loan documents, guarantees and hedging agreements and provide an overview of the methods used to evaluate the effectiveness of the project. The analytical part describes a particular project of development of a residential real estate and its project finance funding. Furthermore, the final section analyses the effectiveness of given project and the parameters of provided project bank loan.

This thesis deals with the issue of business plan of construction company. The aim is to process functional plan for development project, which includes strategic analysis of external and internal environment, marketing mix, implementation plan, financial plan and risk analysis.

The aim of the Master thesis is to analyse the functioning and operations of so-called luxury trains (trains of the Orient-Express-type) and to apply the findings to a concrete example of such a train. The theoretical part deals with the railway transport in the Czech Republic, with a special focus on irregular transport and specifics of the functioning and operations of luxury trains. An overview of the most known luxury trains of nowadays in Europe and all over the world is also a part of the theoretical background. The empirical part analyses the concrete example of a luxury train in a feasibility study. The thesis is based not only on theoretical literature and information from electronic sources, but also on personal consultation with experts on railway transport and luxury trains in the Czech Republic.

The topic of this dissertation thesis is collection, analysis and evaluation of information about investment decisions making within public administration bodies. The investment decision making is examined in relation to allocation of public funds on investment activities and projects. The main goal of this thesis is to analyze and evaluate the current status of the investment decision making within the public sector. Subsequently the goal is to offer new or updated knowledge related to these issues, and bring recommendations to improve the investment decision making of public administration bodies. At first, there are described current knowledge in the field of investment decision making. This is followed by an analysis of assessment methods used for evaluation and selection of investment projects. The work is completed by recommendations for investment decisions making in the form of a normative model. The model should increase benefits of public investment expenses for society. There are used data obtained through a questionnaire survey of 430 subsidized firms, 169 state organizational units and state funds and 130 cities, boroughs and counties. Another important source of information was secondary data of selected ministries and agencies, legislation and literature.

The interview focuses mainly on the theme of contracts Tax stability. thus, the author shows how its development has been in our system in recent years related to mining investment in our country and from the General Mining Act. He also takes a position with regard to measures to promote investment presented by the Government. Finally, the author emphasizes the importance of stability contracts primarily to provide certainty to investors. / La entrevista se centra principalmente en el tema de los contratos de estabilidad tributaria. De esta manera, el autor indica cómo ha sido su desarrollo en nuestro ordenamiento en los últimos años en relación con la inversión minera en nuestro país y a partir la Ley General de Minería. Asimismo, señala su posición con respecto a las medidas para promover la inversión que presentó el Gobierno. Finalmente, el autor enfatiza la importancia de los contratos de estabilidad sobre todo para brindar seguridad jurídica a los inversionistas.

The diploma thesis deals with the construction of Housing Houses in Hodonín. The diploma thesis describes development of Czech development, development phase, feasibility study, construction of the project and appraisal of apartments for sale and commercial premises for rent. In addition a database for market segmentation in Hodonín was created and for subsequent evaluation and evaluation of the effectiveness of the whole development project. Here are some parts of the feasibility study.

The goal of this dissertation is to create a business plan for mr. David Mokrý - owner of café Blue Queen in Boskovice. In a short time he would like to make his business bigger and found another café - pub (Black King).The needed data for creating a project of new successful cafe, which should become the most popular in selected location, I'm going to get by many market analyses, respective by analyses of internal and external neighborhood.

This master ‘s thesis deals with problems of the development and development process. Part of the thesis is a description of the development market in the Czech Republic and significant changes in the construction area in 2017 and 2018. The thesis is focused on the development project in the centre of Brno and the proposal for its next extension. Description of the feasibility study goes smoothly into the proposal to extend the development project. Part of this thesis is a proposal for establishing and functioning of real estate and facility management in the project.