This study investigates how the feminist movement in the city of São Paulo, Brazil, relates to the International Women’s Strike – a transnational feminist mass strike launched by the Argentinian feminist collective Ni Una Menos in 2017. Based on a qualitative analysis of semi-structured interviews conducted with representatives of 10 feminist organizations in São Paulo, this text explores the feasibility of a feminist strike in the context of São Paulo and highlights the structural challenges in its implementation. In addition, the text employs a qualitative literature review to examine the ways in which women in São Paulo have resorted to the strike as an instrument of their resistance since the early 20th century. Theoretically drawing on the theories of direct action and institutionalization of social movements, this work constitutes a synthesis of previous debates and sheds light on the implications that the institutionalization of the Brazilian feminist movement has had on the viability of direct actions such as the feminist strike. A central finding indicates a relative consensus that the feminist movement in São Paulo must first build a massive and popular feminist movement, before an inclusive and intersectional feminist strike can be carried out.