Aim. The overall aims of this study were to develop a tailor-made educational intervention and to examine its effectiveness on short- and longer-term outcomes among Chinese patients with traumatic limb fractures who had undergone surgery. / Background. Fracture limb and undergoing surgery is the common problem after injury. It is the most common source of pain and anxiety and research continues to demonstrate a high prevalence of unrelieved pain in injured patients who have undergone surgery. Patient's belief in pain is the major barrier in pain management. Strategies directed to have appropriate educational interventions are urgently needed to improve patient outcomes for those suffering acute pain after surgery for traumatic limb fracture. / Conclusion. The C-BEI was effective in terms of reducing the pain barrier, providing post-operative pain relief, reducing anxiety, and improving sleep satisfaction in patients with fractured limbs during their first week of hospitalization after surgery. This study has generated evidence supporting the use of a C-BEI in acute pain management. / Method. The study was conducted in the orthopaedic wards of two regional hospitals in Hong Kong and comprised two phases. In phase one, qualitative interviews were conducted with twenty-six Chinese patients who had traumatic limb fractures and were undergoing surgery regarding their experiences of and beliefs about pain management. Ten orthopaedic nurses were also interviewed about their perceived pain management practices and the barriers that prevented better pain control among patients. The findings from these qualitative interviews were used to develop a cognitive behavioural approach educational intervention (C-BEI). C-BEI was used to enhance knowledge of pain, modify their beliefs about pain management and promote positive coping thoughts and behaviour. The C-BEI consisted of two sessions. The first was a 30-minute session comprised a combination of patient education and breathing relaxation exercise and conducted at T0 (1 day before surgery). A 30-minute reinforcement session was conducted at day 7 after surgery (T3). / Results. A total of 125 participants completed the study, with 62 in the experimental group and 63 in the control group. The participants were homogenous in terms of demographic data (P > 0.05) and baseline clinical characteristics (p > 0.05). The short-term outcomes (from T0 to T3) for the participants in the experimental group were a statistically significant with lower pain barrier (p = .003), lower level of pain (p = .003), lower level of anxiety (p < .001), and better sleep satisfaction (p = .001) than the control group. The experimental group had a significantly higher frequency of analgesic use at T2 (p < .001) and better self-efficacy in pain management at T3 (p = .011) than the control group. There were no statistically significant differences in the total length of stay in hospital, although the mean length of stay was shorter in the experimental group than in the control group (8.1 day VS 10.1 days). For longer-term effects, the C-BEI was effective at the post-operative stage in anxiety reduction ( p = .002) and sleep satisfaction improvement (p = .002). There were no statistically significant differences for the VAS pain level, GSE scores, physical health summary component (PCS) and mental health summary component (MCS) of the SF36 between two groups over three months, although the experimental group had better scores in the mental health dimension. Findings of the process evaluation showed that most participants perceived the C-BEI as effective in enhancing their knowledge on pain management and the use of analgesics, and helping them to cope with pain, the could sleep better and regain self-control. / The main study was conducted in phase II which consisted of outcomes and process evaluation. A quasi-experimental design of two groups' pre-test and post-test between subjects was employed for the outcomes evaluation. All participants in the experimental group received the C-BEI and usual care, whereas those in the control group received usual care only. The short-term outcomes were treated as primary outcomes and evaluated in terms of the participants' pain barrier score, pain level (Visual Analogue Pain Scale: VAS, anxiety level (State-Trait Anxiety Inventory:STAI), sleep satisfaction, self-efficacy in pain management (General Self Efficacy Scale: GSE), and frequency of analgesic use. All of which were measured at T0, T1 (day 2), T2 (day 4), and T3 (day 7) after surgery. The total length of stay in hospital of the two groups was also compared. Longer-term outcomes were further evaluated over three months at T4 (1 month) and T5 (3 months), and included the VAS pain level, STAI, sleep satisfaction, GSE and health-related quality of life (SF36).The intention-to-treat method was adopted. The process evaluation involved a qualitative study using telephone interviews. / Wong, Mi Ling, Eliza. / Adviser: Sally Chan. / Source: Dissertation Abstracts International, Volume: 71-01, Section: B, page: 0231. / Thesis (Ph.D.)--Chinese University of Hong Kong, 2009. / Includes bibliographical references (leaves 256-278). / Electronic reproduction. Hong Kong : Chinese University of Hong Kong, [2012] System requirements: Adobe Acrobat Reader. Available via World Wide Web. / Electronic reproduction. Ann Arbor, MI : ProQuest Information and Learning Company, [200-] System requirements: Adobe Acrobat Reader. Available via World Wide Web. / Abstracts in English and Chinese.

O padrão ouro no tratamento cirúrgico das fraturas de tornozelo são as sínteses metálicas, sejam de titânio ou aço. Os implantes bioabsorvíveis foram desenvolvidos para evitar o efeito do stress shielding, ou escudo de carga, e a retirada de material de síntese. O uso de materiais absorvíveis é bem documentado, e com bons resultados em grande número de fraturas craniofaciais. O objetivo deste estudo foi comparar os resultados funcionais de fraturas de tornozelo tratadas com placas metálicas e absorvíveis. Os pacientes foram randomizados e seguidos de forma prospectiva em dois grupos, metálico e absorvível. No período pós operatório imediato os pacientes foram imobilizados com tala gessada por uma semana, substituída por órtese removível por mais 4 semanas. Carga parcial foi autorizada com 3 semanas, e carga total com 6 semanas. Dezenove pacientes foram seguidos por nove meses, e avaliados radiográfica e funcionalmente aos 6 e 9 meses. Todos consolidaram entre 8 e 12 semanas. A recuperação funcional foi similar nos dois grupos. Aos 6 meses, três pacientes no grupo metálico queixaram-se de problemas locais, e tiveram seus implantes removidos. Um paciente do grupo absorvível teve uma deiscência da sutura, tratado com boa evolução. Aos 9 meses foi aplicado o escore da AOFAS para todos os pacientes. Os resultados funcionais foram semelhantes nos dois grupos, após a retirada de implante de três pacientes no grupo metálico. Os implantes absorvíveis permitiram resultados clínicos e funcionais semelhantes aos metálicos em fraturas de tornozelo / The current gold standard fixation system for surgical ankle fractures are the metallic implants, steel or titanium made. Resorbable implants have been developed to avoid stress shielding and a new surgery for implant removal, common with metal implants. Use of resorbable implants is well documented in the literature for a range of craniofacial fractures, with good results. The purpose of this study was to compare the outcome of ankle fractures using biodegradable and metal plates. Patients were randomly and prospectively treated with resorbable or metal fixation system. Post-operatively, the ankle was immobilized with a plaster cast for 1 week, removable cast for other 4 weeks. Half and full weight bearing were allowed at weeks 3 and 6. nineteen patients were followed for 9 months. Functional recovery was similar in both groups at 6 and 9 months, three patients in metal group complained implant-related problems, and had their implants removed, and one in resorbable had an acute dehiscence, solved with surgical debridement and closure. At 6 and 9 months, the AOFAS score was applied for all patients. The functional results were similar in both groups. Implant removal was necessary in three patients from the metallic group. The resorbable plate provided qualitatively similar fracture healing results as the metal plate

O padrão ouro no tratamento cirúrgico das fraturas de tornozelo são as sínteses metálicas, sejam de titânio ou aço. Os implantes bioabsorvíveis foram desenvolvidos para evitar o efeito do stress shielding, ou escudo de carga, e a retirada de material de síntese. O uso de materiais absorvíveis é bem documentado, e com bons resultados em grande número de fraturas craniofaciais. O objetivo deste estudo foi comparar os resultados funcionais de fraturas de tornozelo tratadas com placas metálicas e absorvíveis. Os pacientes foram randomizados e seguidos de forma prospectiva em dois grupos, metálico e absorvível. No período pós operatório imediato os pacientes foram imobilizados com tala gessada por uma semana, substituída por órtese removível por mais 4 semanas. Carga parcial foi autorizada com 3 semanas, e carga total com 6 semanas. Dezenove pacientes foram seguidos por nove meses, e avaliados radiográfica e funcionalmente aos 6 e 9 meses. Todos consolidaram entre 8 e 12 semanas. A recuperação funcional foi similar nos dois grupos. Aos 6 meses, três pacientes no grupo metálico queixaram-se de problemas locais, e tiveram seus implantes removidos. Um paciente do grupo absorvível teve uma deiscência da sutura, tratado com boa evolução. Aos 9 meses foi aplicado o escore da AOFAS para todos os pacientes. Os resultados funcionais foram semelhantes nos dois grupos, após a retirada de implante de três pacientes no grupo metálico. Os implantes absorvíveis permitiram resultados clínicos e funcionais semelhantes aos metálicos em fraturas de tornozelo / The current gold standard fixation system for surgical ankle fractures are the metallic implants, steel or titanium made. Resorbable implants have been developed to avoid stress shielding and a new surgery for implant removal, common with metal implants. Use of resorbable implants is well documented in the literature for a range of craniofacial fractures, with good results. The purpose of this study was to compare the outcome of ankle fractures using biodegradable and metal plates. Patients were randomly and prospectively treated with resorbable or metal fixation system. Post-operatively, the ankle was immobilized with a plaster cast for 1 week, removable cast for other 4 weeks. Half and full weight bearing were allowed at weeks 3 and 6. nineteen patients were followed for 9 months. Functional recovery was similar in both groups at 6 and 9 months, three patients in metal group complained implant-related problems, and had their implants removed, and one in resorbable had an acute dehiscence, solved with surgical debridement and closure. At 6 and 9 months, the AOFAS score was applied for all patients. The functional results were similar in both groups. Implant removal was necessary in three patients from the metallic group. The resorbable plate provided qualitatively similar fracture healing results as the metal plate

Sun, Minghui. / Thesis (Ph.D.)--Chinese University of Hong Kong, 2011. / Includes bibliographical references (leaves 125-159). / Electronic reproduction. Hong Kong : Chinese University of Hong Kong, [2012] System requirements: Adobe Acrobat Reader. Available via World Wide Web. / Abstract also in Chinese.

Osteoporosis, a classical age-related disease and known to be more common in women than in men, has been reported increasingly often in men during the past few years. Although men at all ages after puberty have larger bones than women, resulting in greater bending strength, mortality after a hip fracture, one of the major complications of osteoporosis, is more common in men than in women. Sex hormone deficiency is associated with unrestrained osteoclast activity and bone loss. Even though estrogen deficiency is more pronounced in women, it appears to be a major factor in the pathogenesis of osteoporosis in both genders. In contrast to osteoporosis in postmenopausal women, the treatment of osteoporosis in men has been scarcely reported. Nevertheless, some drugs commonly used for the treatment of osteoporosis in women also appear to be effective in men. The aim of this study is to review primary osteoporosis in the elderly with particular emphasis on gender-related aspects. / Dieser Beitrag ist mit Zustimmung des Rechteinhabers aufgrund einer (DFG-geförderten) Allianz- bzw. Nationallizenz frei zugänglich.

Khoo, Chyi Chyi. / Thesis (M.Phil.)--Chinese University of Hong Kong, 2010. / Includes bibliographical references (leaves 177-204). / Abstracts in English and Chinese; appendix in Chinese. / Abstract(English version) --- p.i / Abstract(Chinese version) --- p.iii / Acknowledgements --- p.iv / List of Tables --- p.vii / List of Figures --- p.ix / List of Abbreviations --- p.x / Publications from this Thesis --- p.xi / Chapter Chapter 1 --- Introduction and Objectives / Chapter 1.1 --- Introduction --- p.1 / Chapter 1.2 --- Objectives --- p.3 / Chapter Chapter 2 --- Literature Review / Chapter 2.1 --- Definitions --- p.4 / Chapter 2.2 --- Epidemiology of Osteoporosis and Fracture --- p.5 / Chapter 2.3 --- Burden --- p.7 / Chapter 2.4 --- Osteoporosis in Men --- p.9 / Chapter 2.5 --- Risk factor of Osteoporosis --- p.11 / Chapter 2.6 --- Prediction of Osteoporosis --- p.13 / Chapter 2.7 --- Risk Factors of Osteoporotic Fracture --- p.15 / Chapter 2.8 --- Prediction of Fracture --- p.28 / Chapter 2.9 --- Difference between men and women --- p.29 / Chapter 2.10 --- DXA and Fracture --- p.31 / Chapter 2.11 --- QUS and Fracture --- p.32 / Chapter 2.12 --- pQCT and Fracture --- p.35 / Chapter 2.13 --- Self-report of Fracture --- p.37 / Chapter Chapter 3 --- Research Outline / Chapter 3.1 --- Non-spine fracture of older men --- p.39 / Chapter 3.2 --- Subjects --- p.40 / Chapter 3.3 --- Measurements of study --- p.41 / Chapter 3.4 --- Record of Fracture --- p.50 / Chapter 3.5 --- Statistical Methods --- p.51 / Chapter Chapter 4 --- Predictors of Non-spine Fracture of Hong Kong Elderly Chinese Men / Chapter 4.1 --- Introduction --- p.52 / Chapter 4.2 --- Subjects and Methods --- p.54 / Chapter 4.3 --- Results --- p.61 / Chapter 4.4 --- Discussions --- p.74 / Chapter 4.5 --- Conclusions --- p.80 / Chapter 4.6 --- Key Points --- p.81 / Chapter Chapter 5 --- Predictive values of QUS for non-spine fracture / Chapter 5.1 --- Introduction --- p.82 / Chapter 5.2 --- Subjects and Methods --- p.84 / Chapter 5.3 --- Results --- p.87 / Chapter 5.4 --- Discussions --- p.92 / Chapter 5.5 --- Conclusions --- p.97 / Chapter 5.6 --- Key Points --- p.98 / Chapter Chapter 6 --- Predictive values of pQCT for non-spine fracture / Chapter 6.1 --- Introduction --- p.99 / Chapter 6.2 --- Subjects and Methods --- p.101 / Chapter 6.3 --- Results --- p.103 / Chapter 6.4 --- Discussions --- p.109 / Chapter 6.5 --- Conclusions --- p.112 / Chapter 6.6 --- Key Points --- p.113 / Chapter Chapter 7 --- Accuracy of self-report of fracture in Asian elderly men / Chapter 7.1 --- Introduction --- p.114 / Chapter 7.2 --- Subjects and Methods --- p.115 / Chapter 7.3 --- Results --- p.116 / Chapter 7.4 --- Discussions --- p.118 / Chapter 7.5 --- Conclusions --- p.121 / Chapter 7.6 --- Key Points --- p.122 / Chapter Chapter 8 --- Conclusions / Chapter 8.1 --- Predictors of Non-spine Fracture of Hong Kong Elderly Chinese Men --- p.123 / Chapter 8.2 --- Predictive values of QUS for non-spine fracture --- p.124 / Chapter 8.3 --- Predictive values of pQCT for non-spine fracture --- p.125 / Chapter 8.4 --- Accuracy of self-report of fracture in Asian elderly men --- p.126 / Chapter 8.5 --- Strength and limitations --- p.127 / Chapter 8.6 --- Implications of the results --- p.129 / Chapter 8.7 --- Future research --- p.130 / Appendix A --- p.131 / Bibliography --- p.178

<p>Pod pojmom politraume se podrazumeva te&scaron;ka istovremena povreda najmanje dve regije tela sa anatomskom težinom povrede AIS koja je jednaka ili veća od tri kao i ukupna izračunata anatomska težina povreda izražena ISS zbirom mora da bude veća od 15. Cilj istraživanja je da se primenom upitnika (SF36, PTSD&ndash;testa i Glazgov skale ishoda) proceni kvalitet života između politraumatizovanih pacijenata sa prelomomima dugih kostiju i politraumatizovanih bez preloma duge kosti kao i da se uoče rani pokazatelji lo&scaron;e prognoze kvaliteta života nakon zavr&scaron;etka lečenja. Istraživanje je prospektivnog karaktera i obuhvatilo je 202 politraumatizovana pacijenta koji su bili povređeni u periodu 2010-2014 godine i bili lečeni u Urgentnom Centu Kliničkog Centra Vojvodine. Od 202 politraumatizovana pacijenta na kontrolne preglede se odazvalo ukupno 72 pacijenta, 37 sa prelomima dugih kostiju - ispitivana grupa i 35 politraumatizovanih pacijenata bez preloma duge kosti koji su činili kontrolnu gupu. Godinu dana nakon zavr&scaron;etka hospitalizacije svaki ispitanik je popunjavao upitnik( SF36, PTSD test i Glazgov skala ishoda ), načinjen je klinički pregled i standardna radiografija predela preloma duge kosti. Rezultati ukazuju da ukupni kvalitet života nakon zavr&scaron;etka lečenja se ne razlikuje značajno između ispitivanih grupa, iako politraumatizovani sa prelomima dugih kostiju imaju niži kvalitet života, odnosno značajno lo&scaron;ije fizički funkcioni&scaron;u i imaju značajno če&scaron;će psihičke poremećaje (postraumatski stresni poremećaj, depresija) u odnosu na kontrolnu grupu. Tip preloma duge kosti nije uticao na krajnji kvalitet života politraumatizovanih, dok su oni sa dva i vi&scaron;e preloma imali značajno lo&scaron;iji kvalitet života. Na osnovu dobijenih rezultata konstatovali smo da veću &scaron;ansu za bolji kvalitet života imaju pacijenti mlađi od 44 godine, ukoliko su inicjalno imali vrednost ISS skora manji od 30,5 bodova, vrednosti sistolnog i dijastolnog arterijskog pritiska u referentnim vrednostima, kao i broja eritrocita i trombocita, i ukoliko su primili manje od 4 jedinica transfuzije krvi u prva 24 časa.</p> / <p>The term of polytrauma means, a patient with multiple severe injuries in at least two regions of the body with anatomical severity of trauma AIS equal or greater than three and the total calculated weight anatomical injuries expressed by ISS score must be greater than 15. The aim of our study is early estimate of quality of life in polytrauma patients with multiple fractures of the long bones and polytrauma patients without fractures of long bones as well as to detect early indicators of poor prognosis of quality of life after treatment, using questionnaires (SF 36, PTSD test and Glasgow Outcome Scale). This was prospective study and included 202 polytrauma patients who were injured during the period 2010-2014 and were treated in the Emergency Center of Clinical Center of Vojvodina. From 202 polytrauma patients, on control examinations responded 72 patients, 37 with fractures of long bones - study group and 35 polytrauma patients without fractures of long bones and they were control group. One year after the end of hospitalization each patient filled out a questionnaire (SF36, PTSD test and Glasgow Outcome Scale), made a clinical examination and standard X-rays of long bone fractures. Our results indicate that the overall quality of life after treatment is not significantly different between the groups, although polytraumatized patients with fractures have a lower quality of life and significantly worse physical functioning and have significantly more mental disorders (post-traumatic stress disorder, depression) compared to the control group. Type of long bone fractures did not affect on the final quality of life, while those patients with two or more fractures had a significantly poorer quality of life. Based on these results we concluded that greater chance for a better quality of life have patients younger than 44 years, unless they had initially ISS score less than 30.5 points, systolic and diastolic blood pressure in the reference values as well as the number of red blood cells and platelets, and if they received less than 4 units of blood transfusions in the first 24 hours.</p>