No description available.

No description available.

No description available.

This study is concerned with a critical comparison of the passive transfer mechanisms of tuberculin and chemical contact hypersensitivities in the guinea pig by use of a four phase experimental approach.

Call number: LD2668 .T4 1950 W3 / Master of Science

Práce se zabývá problematikou financování rozvojových projektů se zaměřením na příklad neprioritní země České republiky. Práce je rozdělena do kapitol, které se jednotlivě věnují rozvojové spolupráci České republiky obecně, zaměřením na neprioritní země, problematikou fundraisingu obecně a analyzuje příklad projektu české neziskové organizace v Guineji.

No description available.

Abstract not available

Contact Lens Acute Red Eye (CLARE) and Infiltrative Keratitis (IK) are inflammatory responses of the eye associated with extended wear of soft contact lenses. Bacterial colonization of contact lenses with Gram-negative bacteria such as Pseudomonas aeruginosa is an important risk factor for the development of these adverse responses. Strategies that control the bacterial colonization of contact lenses may help prevent the occurrence of adverse responses. This thesis aimed to develop an animal model of CLARE/IK to test this hypothesis and to test the effectiveness of contact lenses containing antimicrobial compounds, namely silver and furanone compounds, in controlling corneal inflammation caused by Pseudomonas aeruginosa. A guinea pig model of contact lens wear was developed for the study and it was observed that the ocular responses to contact lens wear in the guinea pig were similar to those seen in human eyes wearing contact lenses. Also, three different models for CLARE/IK were developed and tested in the guinea pig eye. The pathological features of CLARE/IK in the guinea pig were virtually identical to those observed in human eyes. Bacterial contamination of contact lenses was confirmed to be a major risk factor for the development of CLARE/IK. Contact lenses containing nano-particles of silver demonstrated very good antibacterial activity against Pseudomonas aeruginosa in-vitro. The silver lenses were able to control the development of CLARE/IK responses in one of the models for CLARE/IK. Silver lenses might be most effective if used to prevent the establishment of a biofilm of bacteria on a lens such as might occur during storage in a contact lens case. Contact lenses were coated with different concentrations of the furanone compounds by physical adsorption and demonstrated good antibacterial activity at higher concentrations. However these concentrations were cytotoxic in-vitro and lower concentrations of furanones did not possess adequate antibacterial activity to control CLARE/IK responses in-vivo. This thesis has successfully demonstrated that guinea pigs can be used to test the effects of extended wear of contact lenses and developed models to test the pathogenesis of adverse responses such as CLARE/IK. The CLARE/IK models developed could be used to further our understanding of the pathogenesis of these inflammatory conditions and explore the activity of other antimicrobials.

Papua New Guinea gained its independence from Australia in 1975. However, as a developing nation, PNG has continued to depend on external assistance for its development programs. Extensive foreign aid has been expended primarily to enhance the quality of education. To explore the issue of foreign aid and its impact on PNG as a postcolonial society, the dependency and postcolonial theories were adopted to guide the discussion. The theorist Beeby argues that in order to improve the quality of education, the level of general education and training of teachers in developing countries must be raised. This has occurred in PNG but it has not significantly enhanced the quality of education. Consequently, the issue explored concerns the type of educational change occurring in PNG primary teachers’ colleges (PTCs) and its leadership. Globalization processes were adopted to guide the exploration of the education reform and its impact on the quality of education in primary teacher education in PNG. The following questions focused the content of the study:1. What is the quality of education being experienced in the Catholic Primary Teachers’ Colleges? 2. What are the lecturers’, students’, and recent graduates’ perceptions of the recent Primary and Secondary Teacher Education Project innovations occurring in the teachers’ colleges? 3. How is the curriculum in the teachers’ colleges perceived by the lecturers, students and recent graduates? 4. How is leadership demonstrated in the three Catholic Primary Teachers’ Colleges? The epistemological framework of the research was constructionism adopting an interpretivist approach. The specific interpretivist perspective employed was symbolic interactionism because symbolic interactionism places emphasis on the importance of understanding, interpretation and meaning. A case study approach was adopted as the methodology for this research because of the nature of the research purpose. This study involved a total of 166 participants consisting of staff and students from the three Catholic primary teachers’ colleges, representatives from the Catholic Church, National Department of Education (NDOE), Primary and Secondary Teacher Education Project (PASTEP) and other education officers. The data was gathered through a variety of methods including in-depth interviews, participant observation, focus groups, and documentary analysis. The major conclusions that emerged from this study revealed that educational change in primary teacher education has been implemented. However, the study concluded that the quality of leadership demonstrated to lead the educational change was disappointing. Inadequate leadership at the administration and curriculum levels had a negative influence on the quality of education. Achieving quality education was also hampered by inadequate funding, scarcity of resources and inappropriate infrastructure in all the institutions. The two-year trimester program has improved access and quantity but at the expense of quality. To assist primary teacher education implement the reform agenda, foreign aid was required. PASTEP was introduced and the contribution made by PASTEP was substantial. However, the study concluded that some of the strategies adopted by PASTEP to conduct its programs were questionable because there was evidence of hegemonic and colonial practices found among some of its workforce. In accepting foreign aid projects, PNG needs to establish strategies to ensure equitable partnerships with all stakeholders for sustainable development in education. In this respect, the findings of this study may serve as a guide for future decisions about educational leadership, curriculum innovation, donor funding agencies and policy generation.