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Early life cytokines, viral infections and IgE-mediated allergic disease /Larsson, Anna-Karin, January 2006 (has links)
Diss. (sammanfattning) Stockholm : Univ., 2006. / Härtill 4 uppsatser.
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Oropharyngeal muscular inter-relationships in chronic nasorespiratory allergy a cephalometric study : a thesis submitted in partial fulfillment ... orthodontics ... /Eastman, George A. January 1963 (has links)
Thesis (M.S.)--University of Michigan, 1963.
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Oropharyngeal muscular inter-relationships in chronic nasorespiratory allergy a cephalometric study : a thesis submitted in partial fulfillment ... orthodontics ... /Eastman, George A. January 1963 (has links)
Thesis (M.S.)--University of Michigan, 1963.
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Immunomodulatory roles of endotoxin and glutaraldehyde in the development of latex allergyHowell, Michael D. January 1900 (has links)
Thesis (Ph. D.)--West Virginia University, 2002. / Title from document title page. Document formatted into pages; contains xvii, 194 p. : ill. (some col.). Vita. Includes abstract. Includes bibliographical references (p. 163-181).
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The influence of antigen presentation on the induction of the cellular immune responseKerckhaert, Joseph August Marie. January 1900 (has links)
Thesis (doctoral)--Rijksuniversiteit te Utrecht.
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The influence of antigen presentation on the induction of the cellular immune responseKerckhaert, Joseph August Marie. January 1900 (has links)
Thesis (doctoral)--Rijksuniversiteit te Utrecht.
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AvaliaÃÃo clÃnica do uso do oxalato de potÃssio em restauraÃÃes de lesÃes cervicais nÃo-cariosas. / Evaluation of Potassium Oxalate in Restorations of Non-Carious Cervical Lesions.Andrà Mattos de Brito de Souza 17 January 2011 (has links)
CoordenaÃÃo de AperfeiÃoamento de Pessoal de NÃvel Superior / Avaliou-se a eficiÃncia do uso do oxalato de potÃssio (BisBlock â Bisco) em restauraÃÃes de lesÃes cervicais nÃo-cariosas. Para a realizaÃÃo do estudo, foram selecionados vinte pacientes voluntÃrios de ambos os sexos, com idades entre vinte e quatro e cinquenta e cinco anos, com no mÃnimo duas lesÃes que foram restauradas com as tÃcnicas a serem avaliadas. Noventa dentes foram aleatoriamente divididos em dois grupos, a saber: Grupo 1 - RestauraÃÃo pela tÃcnica convencional com o condicionamento Ãcido total e Grupo 2 - RestauraÃÃo com prÃ-tratamento de oxalato de potÃssio seguido da aplicaÃÃo do sistema adesivo. O sistema restaurador adesivo empregado foi o XP Bond (Dentisply) â Durafill (Kulzer). Para a realizaÃÃo das avaliaÃÃes clÃnicas, foi empregado o mÃtodo USPHS modificado, levando-se em consideraÃÃo os seguintes critÃrios: retenÃÃo (R), integridade marginal (IM), descoloraÃÃo marginal (DM), sensibilidade pÃs-operatÃria (S), cÃrie (C), forma anatÃmica (FA). As avaliaÃÃes clÃnicas foram realizadas por dois avaliadores nos perÃodos imediato (Baseline), seis meses e um ano. A intensidade da sensibilidade dolorosa foi avaliada antes e apÃs o tratamento utilizando-se uma escala de medida verbal. Ao final de um ano, os resultados de restauraÃÃes clinicamente satisfatÃrios (Alfa e Bravo) obtidos para o grupo controle e experimental foram respectivamente: R (97%/89%), IM (100%/100%), DM (100%/100%), S (100%/100%), C (100%/100%), FA (100%/100%). Os resultados foram submetidos à anÃlise estatÃstica com os testes de Kruskal-Wallis e Mann-Whitney para os nÃveis de sensibilidade e o exato de Fisher para os demais critÃrios com o nÃvel de significÃncia de 5% (p<0,05). Com base na anÃlise estatÃstica dos resultados, conclui-se que o emprego do oxalato de potÃssio como agente de prÃ-tratamento dentinÃrio nÃo influenciou no desempenho clÃnico das restauraÃÃes de lesÃes cervicais nÃo-cariosas ao final de um ano. / The aim of this study was to evaluated the efficiency of the use of potassium oxalate (BisBlock - Bisco) in restorations of non-carious cervical lesions. Twenty volunteers patients of both sexes, aged between twenty-four and fifty-five years old, with at least two lesions that were restored with the techniques to be evaluated were selected. Ninety teeth were randomly divided into two groups: Group 1- Restoration with total-etch technique and Group 2 â Restoration with pre-treatment with potassium oxalate followed by application of adhesive system. The adhesive restorative system used was XP Bond (Dentisply) - Durafill (Kulzer).
The clinical evaluation was employed USPHS modified method, taking into account the following criteria: retention (R), marginal integrity (MI), marginal discoloration (MD), postoperative sensitivity (S), caries (C), anatomic form (AF). Clinical assessments were conducted by two examiners in the periods baseline, 6 months and 1 year. The intensity of pain sensitivity was assessed before and after treatment using a verbal rating scale. After one year the results of restorations clinically satisfactory (Alfa and Bravo) obtained for the control and experimental group were: R (97% / 89%), MI (100% / 100%), MD (100% / 100%), S (100% / 100%), C (100% / 100%), FA (100% / 100%). The results were analyzed statistically with Kruskal-Wallis and Mann-Whitney tests for levels of sensitivity and the Fisher exact test for the other criteria with a significance level of 5% (p <0.05). Based on statistical analysis, we conclude that the use of potassium oxalate as an agent of dentin pre-treatment did not influence the clinical performance of restorations in non-carious cervical lesions after one year.
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Avaliação clinica do efeito do fluoreto de sodio sobre a sensibilidade dentinaria, a saude gengival e a satisfação do paciente durante o clareamento dental caseiro com peroxido de carbamida a 10% / Clinical evaluation of the effect of sodium fluoride on dentin hypersensitivity, gingival health and patient satisfaction during 10% carbamide peroxide at-home bleachingLobo, Maristela Maia 08 August 2008 (has links)
Orientadores: Giselle Maria Marchi Baron, Carlos Eduardo Francci / Tese (doutorado) - Universidade Estadual de Campinas, Faculdade de Odontologia de Piracicaba / Made available in DSpace on 2018-08-12T16:01:12Z (GMT). No. of bitstreams: 1
Lobo_MaristelaMaia_D.pdf: 970564 bytes, checksum: cceba3a37b5226f311ffa842569a6760 (MD5)
Previous issue date: 2008 / Resumo: Este estudo clínico randomizado e duplo-cego avaliou os efeitos do fluoreto de sódio, presente na composição do gel clareador (0,11%) e/ou aplicado topicamente em moldeira (2%), sobre a sensibilidade dentinária, a saúde gengival e a satisfação de pacientes submetidos ao clareamento dental caseiro com peróxido de carbamida a 10%. Sessenta voluntários foram, aleatoriamente, divididos em seis grupos (n=10): (G1) gel de peróxido de carbamida a 10%+ gel de flúor a 2%; (G2) gel de peróxido de carbamida a 10% + placebo do gel de flúor a 2%; (G3) placebo do gel clareador + gel de flúor a 2%; (G4) placebo do gel clareador + placebo do gel de flúor a 2%; (G5) gel de peróxido de carbamida a 10% contendo 0,11% de fluoreto de sódio + gel de flúor a 2%; (G6) gel de peróxido de carbamida a 10% contendo 0,11% de fluoreto de sódio + placebo do gel de flúor a 2%. Esses voluntários trataram seus dentes durante a noite por, no mínimo, 4 horas, durante 14 dias consecutivos. Após cada jornada de clareamento, eles aplicavam o gel de flúor (ativo ou placebo) na moldeira por 5 minutos. Na consulta de baseline, 7, 14, 21 e 28 dias após o início do clareamento, foram avaliados: sensibilidade a estímulos tátil e evaporativo (através de escala analógica visual de dor), satisfação do voluntário (através de questionário, nos retornos de 7 e 14 dias), e parâmetros periodontais (após 14 e 28 dias). Do total de voluntários avaliados, 47,36% demonstraram sensibilidade ao estímulo evaporativo e 17,54% ao estímulo tátil, sem diferença estatística entre os grupos. A satisfação positiva para este tratamento foi de 61,4%. Houve uma significativa diminuição da profundidade de sondagem avaliada no retorno de 14 dias, e não houve diferença estatística entre os grupos com relação ao índice de sangramento. Pode-se concluir que o flúor, nas concentrações avaliadas, não foi capaz de evitar ou diminuir a ocorrência de sensibilidade associada ao clareamento dental caseiro com peróxido de carbamida a 10%. / Abstract: This double-blind and randomized clinical trial evaluated the effects of sodium fluoride - within the composition of bleaching gel (0,11%) or topically applied (2%) - over dentin hypersensitivity, gingival health and overall satisfaction of patients submitted to 10% carbamide peroxide nightguard vital bleaching. Sixty volunteers were randomly assigned to six groups (n=10): (G1) 10% carbamide peroxide gel + 2% neutral fluoride gel; (G2) 10% carbamide peroxide gel + placebo fluoride gel; (G3) placebo bleaching gel + 2% neutral fluoride gel; (G4) placebo bleaching gel + placebo fluoride gel; (G5) 10% carbamide peroxide gel with 0,11% sodium fluoride + 2% neutral fluoride gel; (G6) 10% carbamide peroxide gel with 0,11% sodium fluoride + placebo fluoride gel. Treatment was conducted for 14 consecutive days, and after each night of bleaching volunteers wore trays with topic fluoride gels (active or placebo) for 5 minutes. At baseline and after 7, 14, 21 and 28 days from the beginning of treatment, were evaluated: dentin sensitivity to tactile and evaporative stimuli (using analogue VAS scale), volunteer satisfaction (applying questionnaire at recalls 7 and 14), and periodontal health (at recalls 14 and 28). From the total of volunteers evaluated, 47.36% demonstrated evaporative sensitivity and 17.54% tactile sensitivity, with no statistical difference between groups. Positive satisfaction achieved 61.4%, with a mean bleaching of three tons of Vita scale for active groups and no influence of fluoride. Probing depth was lower at second recall (day 14), but there was no statistical difference for bleeding on probing between groups. In conclusion, different concentrations of sodium fluoride were not capable of preventing or diminishing dentin sensitivity during 10% carbamide peroxide nightguard vital bleaching. / Doutorado / Dentística / Doutor em Clínica Odontológica
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AvaliaÃÃo in vitro do efeito da escovaÃÃo com dentifrÃcios clareadores sobre a superfÃcie dentinÃria / In vitro evaluation of the toothbrushing effect with whitening toothpaste abrasion on root dentineGustavo Henrique Apolinario Vieira 30 March 2012 (has links)
CoordenaÃÃo de AperfeiÃoamento de Pessoal de NÃvel Superior / Conselho Nacional de Desenvolvimento CientÃfico e TecnolÃgico / A escovaÃÃo tem um papel importante na etiologia da hipersensibilidade dentinÃria. AbrasÃo pode estar relacionada a abrasivos contidos nos dentifrÃcios. O objetivo deste estudo foi comparar por perfilometria mecÃnica o efeito da abrasÃo da escovaÃÃo com dentifrÃcios clareadores e convencionais na dentina radicular. Noventa espÃcimes de dentina (4 x 4 x 2mm) foram aleatoriamente divididos em cinco grupos experimentais (n=18) de acordo com os dentifrÃcios: trÃs clareadores (W1, W2, e W3) e dois convencionais (C1 e C2), produzidos por dois fabricantes distintos. Utilizando uma mÃquina de escovaÃÃo, cada espÃcime foi escovado com carga constante de 300g por 2500 ciclos (4,5 ciclos por segundo). Os dentifrÃcios foram diluÃdos na proporÃÃo de 1:3 em peso (dentifrÃcio/saliva artificial). A ponta diamantada do perfilÃmetro moveu-se em velocidade constante de 0,05mm/s com forca de 0,7mN. O valor mÃdio das leituras da abrasÃo da escovaÃÃo (μm; mÃdia  desvio padrÃo) foi obtido de cinco leituras consecutivas em cada espÃcime: W1 = 8,86  1,58, W2 = 8,27  2,39, W3 = 7,59  1,04, C1 = 2,94  1,29 C2 = 2,89  1,05. Houve diferenÃa estatisticamente significante entre os grupos (ANOVA - p<0.0001). O teste de Tukey para mÃltiplas comparaÃÃes mostrou diferenÃas entre todos os dentÃfricios clareadores e os convencionais, mas nÃo entre os clareadores e os convencionais entre si. DentifrÃcios clareadores podem causar mais abrasÃo na dentina do que os convencionais. / Toothbrushing abrasion has an important role in the etiology of dentine hypersensitivity. The abrasion may be related to the abrasivity of the toothpaste. The aim of this study was to compare by mechanical profilometry the effect of toothbrushing abrasion with whitening and regular toothpastes on root dentine. Ninety dentine specimens (4x4x2 mm) were randomly divided into five experimental groups (n=18) according to the toothpaste: three whitening (W1, W2 and W3) and two regular toothpastes (C1 and C2), produced by two different manufacturers. Using a brushing machine, each specimen was brushed with constant load of 300g for 2500 cycles (4.5 cycles/second). The toothpastes were diluted at a ratio of 1:3 w/w (dentifrice/distilled water). The brush diamond tip of the profilometer moved at a constant speed of 0.05 mm/s with a force of 0.7 mN. The average reading value of brushing abrasion (μm; mean  standard deviation) was obtained from five consecutive measurements of each specimen: W1 = 8.86  1.58, W2 = 8.27  2.39, W3 = 7.59  1.04, R1 = 2.94  1.29 and R2 = 2.89  1.05. There was a significant difference between groups (ANOVA - p<0.0001). Post-hoc Tukey test for multiple comparison showed differences between all the whitening toothpastes and the regular ones, but not among the whitening or the regular against each other. Whitening toothpastes can cause more dentine abrasion than the regular ones.
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Immunophenotypic Analysis of Peripheral Blood and Synovial Fluid Lympocytes from Patients with Failed Hip ImplantsHurda, Ian January 2013 (has links)
Metal-on-metal (MM) bearings have been considered as an alternative to conventional metal-on-polyethylene (MPE) bearings because of their lower volumetric wear, but concern exists due to potential metal hypersensitivity. Metal hypersensitivity reactions have been thought to be T cell-mediated delayed type hypersensitivity (DTH) reaction. However some of the MM periprosthetic tissues show the presence of B- and plasma cells, as well as massive fibrin exudation, which are not characteristic of a DTH reaction. Therefore, the exact nature of the hypersensitivity reaction(s) MM implants remains unclear. The present study aimed to compare the phenotypes of lymphocytes from the peripheral blood and synovial fluid of patients with failed MM and MPE implants, and from volunteers with no implant (peripheral blood only). Results in peripheral blood showed differences in the T-cell populations depending on the implant type. This included differences in the proportions of T-helper and T-cytotoxic cells, and T-cells expressing IFN-g. Results in synovial fluid showed a significant difference between MM and MPE groups for the B-cells. Both groups depicted a predominance of T-cell lymphocytes in synovial fluid and overall larger proportions of memory cells than in peripheral blood, but group sizes were rather small. Overall, T-cell cytokine expression (analyzed in peripheral blood only because of the limited number of synovial fluid samples) did not exhibit characteristics of a DTH reaction and the proportions of memory lymphocytes did not indicate activation of a specific subset in the MM group. Nevertheless, group sizes still remain to be increased.
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