Approved for public release; distribution in unlimited. / A noticeable civil-military gap has emerged in American society where the public does not fully understand the mission of the military, and the military does not understand the expectations and demands by the public in a liberal democracy. Maintaining a good rapport with the media and not fostering a civil-military gap will allow the public to embrace 'good news' stories that are introduced by the military as well as accept the times when a negative story breaks the news. Cooperating with the media by allowing appropriate access to the military is vital to effective information operations. This research identifies instances of failure in military-media relationships by reviewing the historical relationship between the media and military in wartime as well as two examples in the last 15 years in which the Navy has mishandled newsworthy events-the 1989 explosion aboard the USS IOWA and the 2001 collision between the submarine, USS GREENEVILLE and the Japanese fishing trawler, Ehime Maru. The purpose of this project is to determine and ultimately to mitigate military bias against the media. / Lieutenant, United States Navy

Lo scopo della presenta ricerca è analizzare il ruolo del sistema di ricompensa in relazione al costrutto BIS/BAS (Behavioural Inhibition System/ Behavioural Activation System) in un contesto sano e di dipendenza da sostanza. Il lavoro ha inoltre esplorato l'asimmetria cerebrale frontale nelle scelte decisionali che implicano stimoli di ricompensa e condizioni punizione. I risultati hanno confermato l'ipotesi di un anomalia del sistema di ricompensa in individui con alto BAS e in pazienti con dipendenza da sostanza, che sovrastimavano la ricompensa immediata a scapito di quella a lungo termine durante l’Iowa Gambling Task. Un’altra componente cruciale emersa da questo progetto è una iper-attivazione del lobo frontale di sinistra rispetto a quello di destra in risposta alle opzioni più rischiose. Questo "effetto di sbilanciamento inter-emisferico” potrebbe essere considerato come un indicatore critico del comportamento decisionale disfunzionale nella dipendenza o come fattore di vulnerabilità allo sviluppo di dipendenze. Infine, questo "modello di squilibrio corticale" è stato applicato ad altre forme di dipendenza comportamentale, misurate con l’Internet Addiction Test (IAT). In effetti, un aumento dell'attività frontale di sinistra è stata osservata per gli individui ad alto IAT in risposta a stimoli premianti. In particolare, i risultati ottenuti sottolineano l'importanza di un modello integrato di dipendenza che tiene conto del sistema motivazionale (BIS/BAS) correlato alla lateralizzazione dell'attività corticale. / The aim of this PhD research was intended to analyze the role of the reward system by the BIS/BAS (Behavioural Inhibition System/ Behavioural Activation System) construct in healthy and addiction context. It explored the frontal brain asymmetry in decisional choices implying reward stimuli and punishment conditions. Results confirmed the hypothesis of a “reward bias” induced by high-BAS individuals and patients suffering from Substance Use Disorder (SUD) to overestimate the immediate reward to the detriment of the delayed reward during the Iowa Gambling Task. Another critical component is the frontal left-hyper activation of the brain in response to more risky options. This "inter-hemisphere" unbalancing effect can be considered as a critical indicator of the dysfunctional decision behavior in dependence or as a vulnerability factor to the development of addiction. Finally, this “cortical imbalance model” was applied to other forms of behavioural addiction, measured by the Internet Addiction Test (IAT). Indeed, an increased left frontal activity was observed for high-IAT individuals in response to rewarding stimuli. In particular, the results underlined the importance of an integrated model of addiction that takes into account the motivational system (BIS / BAS) related to the lateralization of cortical activity.

Decision-making is necessary to adapt to the variable environment in everyday life. During this process, our goal is to select the most beneficial course of action in order to obtain the best outcome, to develop efficient choice strategies. That is, estimating the probability to obtain any of the available outcomes as well as their value. Moreover, poor decision-making ability is a common symptom to several psychiatric disorders, such as pathological gambling, depression, schizophrenia and bipolar disorder.The cognitive and emotional mechanisms controlling decision-making processes depend, among others, on the striatum, Basal Ganglia’s main input nucleus. The striatum is divided into the dorsal striatum, responsible for motor and cognitive control that initiate actions (Dorsomedial Striatum, DMS) and generate habits (Dorsolateral Striatum, DLS), and Nucleus Accumbens (NAc) which manages reward and the influence of motivation on motor behavior. A2A-expressing and D1-expressing medium spiny neurons (iMSNs and dMSNs, respectively), accounting for 95% of striatal neurons act in coordination to generate adaptive behavioral responses. It has been shown that imbalanced activity between these two populations leads to abnormal behaviors: overactivation of striatonigral neurons promotes an increased locomotion as well as a higher sensitivity for reward, whereas overactivation of striatopallidal neurons produces the exact opposite effects. However, the specific contributions to decision-making of these two populations in each striatal territory remains unclear. Here, we made use of a chemogenetic (DREADD) tool to manipulate striatal projection neurons’ activity within each specific striatal area and tested their role in a decision-making operant protocol. To do so, we used two different mouse models that allowed us to target specifically iMSNs (A2A-Cre mice) or dMSNs (D1-Cre mice) and induce neuronal-specific expression of the hM3Dq DREADD receptor. CNO-mediated activation of these receptors led to neuronal activation. Then, we tested DREADD-dependent activation of MSNs during the Iowa Gambling Task (IGT), a test used to assess the influence of different rewards on choice and to evaluate the ability of mice to develop advantageous choice strategies. We found an exclusive role of DMS’ dMSNs in controlling choice preference, as DREADD-induced activation of these neurons produced a loss of preference. Manipulations of MSNs in other striatal areas led to altered task performance without affecting choice preference.These results contribute to a better understanding of the role of the striatum on decision-making and moreover, suggest the existence of a high level of functional specialization in this area, a fact that could be explained by the local circuits in which each MSN population is involved. / Doctorat en Sciences biomédicales et pharmaceutiques (Médecine) / info:eu-repo/semantics/nonPublished

More than 13,000 deaths and $340 million in health care costs are the result of catheter-associated urinary tract infections (CAUTIs) annually in the United States. CAUTIs can also result in acute patient discomfort and potentially preventable exposure to antibiotics. The hospital for which this quality improvement project was developed was above the National Healthcare Safety Network CAUTI bench mark. Framed within the Iowa model of evidence-based practice, a multidisciplinary team of 8 hospital stakeholders guided the project (n=8). The purpose of the project was to develop an indwelling urinary catheter maintenance checklist using evidence-based practice guidelines related to preexisting inappropriate risk factors for catheterization and appropriate indications for catheterization, as well as evidence-based maintenance practices for care of the indwelling catheter. Each piece of evidence to be included in the checklist was evaluated by 4 content experts using a 10 item 5 point Likert scale ranging from 'strongly disagree' to 'strongly agree'. Descriptive analysis showed an average of 4.8/5 for all items with 'agree' being voiced in two of the items rather than 'strongly agree'. The checklist was completed and presented to hospital senior leadership who recommended that the checklist be incorporated into the hospital CAUTI prevention plan. All project team members (n=8) completed an 8 item 5 point Likert scale summative evaluation of the purpose, goal, objectives, and my leadership which averaged as 5 or 'strongly agree' supporting the development of the project. Implications for social change include improved patient outcomes, mindful stewardship of healthcare dollars, and increased patient and family satisfaction.

The current investigation supports the objectives of Project GEMS (Roberts, 2008), a grant funded program whose objectives include the development and validation of a protocol to identify students from underrepresented and diverse populations as gifted in the content areas of science, technology, engineering and mathematics. Identification of students from low-income and diverse populations as gifted has been a struggle with current assessment techniques (Baldwin, 2005). Project GEMS aims to address this problem through development of interest measures specific to the STEM areas for use within an identification protocol. The current project developed a measure to assess interest in mathematics. The construct of interest was targeted as it is correlated with many positive factors in education that lead to increased academic performance (Schunk, Pintrich, & Meece, 2008). Existing math interest inventories are designed for older populations, lack good psychometric properties and are atheoretical. To improve upon existing interest measures, Hidi and Renninger’s (2006) four-phase model of interest served as the theoretical basis to inform and guide the process of development and validation of a math interest inventory. A twenty-seven item self-report math interest measure was designed to assess the four phases of Hidi and Renninger’s interest model (emotion, value, knowledge, and engagement; 2006). Pilot and field testing of the measure were conducted in elementary schools selected on the basis of a high proportion of low-income students in a south central Kentucky school district. The sample consists of 1,429,429 students in grades two through six. The measure was hypothesized to evidence good internal consistency, a four-factor structure, and a significant and positive correlations between the Iowa Test of Basic Skills and the composite and subscales of the math interest inventory. The first hypothesis found support with an internal consistency reliability coefficient of .916 for the overall score. Results of confirmatory factor analysis supported a four-factor structure resembling Hidi and Renninger’s (2006) four phase model of interest and including the four components emotion, value, knowledge, and engagement. The correlations between the math scores from the Iowa Test of Basic Skills and the math interest inventory total score and scales partially supported the last hypothesis. The correlations were small and positive for the Values and Knowledge scales but small and negative for the Emotion and Engagement scales. The correlations for the total score of the math interest inventory were significant; however, their values had little practical significance. While the math interest measure evidences good reliability and support for the structure of the scales through confirmatory factor analysis, the current study did not provide evidence for a significant relationship with math achievement as measured by a standardized group administered math achievement test. These results are discussed in relation to limitations of the current study and recommendations for further investigation.

Thesis (D. Min.)--Covenant Theological Seminary, 2002. / Abstract. Includes bibliographical references (leaves 262-267).

Neuropsychological deficits may perpetuate the risk and chronicity of psychiatric disorder. Borderline Personality Disorder, characterized by significant suicide risk, intense affect and behavioural dysregulation, is frequently associated with the executive function (EF) deficits of decision making and inhibitory control. However, the role of inhibitory control on decision making remains poorly understood. This study examined the relationships among working memory, cognitive and motor inhibitory control, and IGT decision-making performance in 41 women with BPD and 41 healthy controls. Associations among EF and suicide risk were also explored. Experimental tasks included the Iowa Gambling Task, Digit Span, Stroop and Stop Tasks, and Raven’s Matrices. Only IGT decision-making deficits distinguished BPD subjects from healthy controls. Weaker yet normal range IQ and EFs in BPD women did not explain their disadvantageous IGT performance. Contrary to expectations, IGT deficits in BPD women did not predict any suicidal risk; however, intact interference control was as sensitive to suicidal risk as was depression. Normal interference control was associated with a reduction in suicide risk. While IGT decision making may be a marker for BPD, Stroop interference control is more sensitive to suicide risk and may represent a vulnerability for suicide that exists beyond psychiatric diagnosis.

Operant acquisition, operant expression, and decision-making differentially rely on brain areas that are differentially affected by antipsychotic and other dopaminergic drugs. The purpose of this thesis was to test if the known differential pharmacological and location of action of antipsychotic and other dopaminergic drugs predict the drug effects on operant acquisition, operant expression, and decision-making. Clozapine and to a lesser extent, risperidone but not metoclopramide or haloperidol affect the prefrontal cortex (PFC); haloperidol, metoclopramide, and to a lesser extent, risperidone affect the dorsolateral striatum (DLS). We used amphetamine as a broadly-acting indirect dopamine (DA), serotonin (5-HT), and norepinephrine agonist. We found that all antagonists altered operant acquisition and expression, but in different ways. The DA D2-like receptor antagonists blunted reinforcement impact during operant acquisition and induced an extinction-like decline in expression whereas the atypical antipsychotics with high PFC 5-HT-2A affinity maintained inactive lever presses during acquisition, but produced tolerance in expression. Curiously, risperidone and metoclopramide, but not clozapine or haloperidol, more potently suppressed lever pressing in acquisition than expression. In contrast, amphetamine suppressed operant expression, but not acquisition, at a dose range that increased locomotion and induced conditioned place preference. Amphetamine decreased sensitivity to reward presentation and inactive lever pressing during operant acquisition, but had the opposite effects during expression. A very different pattern was found in the rodent gambling task (rGT), a model of the 4- choice (deck) Iowa Gambling Task used in humans. The rGT puts small, immediate rewards that are advantageous in the long-term due to generally fewer and shorter associated penalties in conflict with large, immediate rewards that are disadvantageous in the long-term due to generally more and longer associated penalties. Two antipsychotics (risperidone, haloperidol) but not the anti-emetic (metoclopramide) enhanced performance by shifting preferences towards advantageous options, but the antipsychotic that induces PFC Fos (clozapine) impaired performance. Amphetamine decreased discrimination among different decks in the rGT. These data demonstrate the differential effects of clinically relevant drugs on decision-making and different stages of operant learning. The differential effects on operant responding and decision-making of different antipsychotic drugs provide important information regarding their therapeutic and side-effect profiles. / Thesis (Ph.D, Psychology) -- Queen's University, 2013-03-14 16:12:57.629

Neuropsychological deficits may perpetuate the risk and chronicity of psychiatric disorder. Borderline Personality Disorder, characterized by significant suicide risk, intense affect and behavioural dysregulation, is frequently associated with the executive function (EF) deficits of decision making and inhibitory control. However, the role of inhibitory control on decision making remains poorly understood. This study examined the relationships among working memory, cognitive and motor inhibitory control, and IGT decision-making performance in 41 women with BPD and 41 healthy controls. Associations among EF and suicide risk were also explored. Experimental tasks included the Iowa Gambling Task, Digit Span, Stroop and Stop Tasks, and Raven’s Matrices. Only IGT decision-making deficits distinguished BPD subjects from healthy controls. Weaker yet normal range IQ and EFs in BPD women did not explain their disadvantageous IGT performance. Contrary to expectations, IGT deficits in BPD women did not predict any suicidal risk; however, intact interference control was as sensitive to suicidal risk as was depression. Normal interference control was associated with a reduction in suicide risk. While IGT decision making may be a marker for BPD, Stroop interference control is more sensitive to suicide risk and may represent a vulnerability for suicide that exists beyond psychiatric diagnosis.

This dissertation complements those analytical studies which discuss choral works and techniques of contemporary choral composition, by examining what twentieth-century literature was actually performed within one of the choral traditions of the United States.The a cappella choral tradition has spread widely throughout the United States. Previous studies have examined the history of the pioneering a cappella choirs and the biographies of the movement's leaders. This study also complements them in examining another aspect of the a cappella tradition.Three representative choirs were chosen: the Concordia Choir from Moorhead, Minnesota, Paul J. Christiansen, conductor; the Nordic Choir of Luther College from Decorah, Iowa, Weston Noble, conductor; and the St. Olaf Choir from Northfield, Minnesota, Kenneth Jennings, conductor. These choirs were selected because each had a long tradition of touring -- consequently exposing a broader public to the literature they performed, because each choir has been widely acknowledged for performance excellence, and because each has had remarkable continuity in leadership -having only one or two conductors during the thirty-six year span included in this study.The program archives of each choir were examined to determine the twentieth-century literature which had been performed. Three conductors, Paul J. Christiansen, Kenneth Jennings, and Weston Noble, were interviewed with regard to their ideas concerning selection and preparation of twentieth-century choral music.Though each choir was found to have some distinct patterns, there were also several elements in common among the choirs:1. Each took. seriously the relationship between music and text, and the fact that the choirs were representatives of Lutheran colleges.2. Each emphasized the highest possible level of performance in order that the expressive and aesthetic qualities of the music sung would be comprehended by both singers and audience.3. Each has given a prominent place to twentieth-century music by American composers.4. Each has given a comparatively minor role to music by Scandinavian composers.5. Each has repeated certain works several times during the thirty-six years, helping to establish them in the choral repertory.6. Each has performed an approximately constant quantity of twentieth-century music during the thirty-six years, but each has tended to program progressively more challenging works as time goes on. Appendices present listings of the choral literature included in the study, of the repertory for each choir, and of currently available recordings by the three choirs of twentieth-century choral music. / School of Music