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1	Altered White Matter Connectivity in Young Acutely Underweight Patients With Anorexia Nervosa Geisler, Daniel, King, Joseph A., Bahnsen, Klaas, Bernardoni, Fabio, Doose, Arne, Müller, Dirk K., Marxen, Michael, Roessner, Veit, van den Heuvel, Martijn, Ehrlich, Stefan 06 March 2023 (has links) Objective: Reductions of gray matter volume and cortical thickness in anorexia nervosa (AN) are well documented. However, findings regarding the integrity of white matter (WM) as studied via diffusion weighted imaging (DWI) are remarkably heterogeneous, and WM connectivity has been examined only in small samples using a limited number of regions of interest. The present study investigated whole-brain WM connectivity for the first time in a large sample of acutely underweight patients with AN. Method: DWI data from predominantly adolescent patients with acute AN (n ¼ 96, mean age ¼ 16.3 years) and age-matched healthy control participants (n ¼ 96, mean age ¼ 17.2 years) were analyzed. WM connectivity networks were generated from fiber-tractography-derived streamlines connecting 233 cortical/subcortical regions. To identify group differences, network-based statistic was used while taking head motion, WM, and ventricular volume into account. Results: Patients with AN were characterized by 6 WM subnetworks with abnormal architecture, as indicated by increased fractional anisotropy located primarily in parietal-occipital regions and accompanied by reduced radial diffusivity. Group differences based on number of streamlines reached only nominal significance. Conclusion: Our study reveals pronounced alterations in the WM connectome in young patients with AN. In contrast to known reductions in gray matter in the acutely underweight state of AN, this pattern does not necessarily indicate a deterioration of the WM network. Future studies using advanced MRI sequences will have to clarify interrelations with axonal packing or info:eu-repo/classification/ddc/150 ddc:150 info:eu-repo/classification/ddc/610 ddc:610
2	Monitoring Cerebral Functional Response using sCMOS-based High Density Near Infrared Spectroscopic Imaging Langri, Dharminder Singh 02 August 2019 (has links) No description available. Biomedical Engineering Optics Biomedical Research Engineering Camera Fiber fNIRS sCMOS High Density Hemodynamics oxygenated and deoxygenated hemoglobin Continuous Wave In-Vivo Dynamic Flow Phantom Autism Non-invasive Long term monitoring Intra-operative Portable Cheap Imaging Fiber bedside monitoring

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Altered White Matter Connectivity in Young Acutely Underweight Patients With Anorexia Nervosa

Monitoring Cerebral Functional Response using sCMOS-based High Density Near Infrared Spectroscopic Imaging