L'enseignement de l'évolution du vivant en Tunisie souffre d'une précarité du statut scientifique en raison de son interférence avec les croyances religieuses des élèves, d'un contexte concordiste et d'une déficience de formation scientifique en évolution. Les élèves ont des difficultés avec la méthodologie de validation par enquête et conçoivent une équivalence argumentative entre référentiels argumentatifs scientifique et théologique. Une action innovante dans l'enseignement de l'évolution en Tunisie est proposée pour militer au statut scientifique. C'est un dispositif d'enseignement qui traite de deux obstacles au statut scientifique de l'évolution par des réflexions épistémologiques en débats de classe. Ces réflexions distanciées accompagnent une construction de savoirs en méthodologie de validation par enquête. Ces savoirs devaient aider les élèves à comprendre le statut scientifique de l'évolution du vivant. La proposition conçue est mise à l'essai et évaluée. La déstabilisation et l'identification des deux obstacles au statut scientifique de l'évolution a permis de caractériser le référentiel scientifique de l'évolution du vivant.

<p>The aim of the study was to show whether or not there exists, and if so, to understand, a common creativity, vision and imagination of the members of Småland’s Entrepreneurial Academy’s organisation.</p><p>The method used for this research is the fictive narrative collage , which consists of the collection of fictive stories. The author has also made her own additions to the method. A composer composes songs to the narratives, two artists illustrate the narratives. The research is carried out on the total population within Småland’s Entrepreneurial Academy which consists of 10 permanent members of the organisation.</p><p>The theory focuses on different areas, such as creativity, vision and imagination as well as on the entrepreneur and the organisation. The latter two to provide the research with a foundation for the whole.</p><p>Analyses were carried out and interpreted by the author, coupled to the theory, but also with a starting point in the interpretations that the composer and artists made in their contributions. Theatrical metaphors are used to draw parallels and to make further clarifications in the interpretation and the texts.</p><p>The results show that vision, imagination and creativity do exist and common characteristics have been able to be identified, such as the creativity of the entrepreneur and his or her desire to go his or her own way, to not enter into conflict with his or her own role. In the vision, there are common trains of thought, where a balance in life/existence is the most central. If imagination is allowed completely free flight, the research group will allow anarchy to reign.</p>

Thesis (D. Min.)--Northern Baptist Theological Seminary, 2003. / Abstract. Includes bibliographical references (leaves 146-151).

Thesis (M.A.)--Catholic Theological Union at Chicago, 2000. / Vita. Includes bibliographical references (leaves [84]-87).

Thesis (M.A.)--Catholic Theological Union at Chicago, 2003. / Includes bibliographical references (leaves 149-151).

An understanding of the damage evolution prior to crack initiation in advanced structural materials is of vital importance to the fatigue community in both academia and industry. Features known as the Persistent Slip Bands (PSBs) play an integral role in this damage evolution. Therefore, PSBs have been the focus of a lot of science-based investigations over the years. However, most existing studies in this area are restricted to analysis of PSBs in single crystal face centered cubic (FCC) materials. Moreover, these studies lack a quantitative analysis of the evolution of the fatigue damage (or PSBs) as a function of the material microstructure. This is especially true for relatively modern materials such as the Advanced High Strength Structural (AHSS) steels that are gaining a lot of importance in the automotive sector. Accordingly, the objective of this research is to quantitatively characterize evolution of PSBs in three AHSS steels having different microstructures as a function of number of fatigue cycles and strain amplitude. For this purpose strain controlled interrupted fatigue tests have been performed on two dual phase steels (DP-590 and DP-980) having different relative amounts of tempered martensite and a ferritic high strength low alloy steel (HR-590). Digital image analysis and Stereology have been used for unbiased quantitative characterization of the evolution of global geometry of the PSB colonies as function of number of fatigue cycles and strain amplitude. Evolution of PSB colonies has been couched in terms of variation of PSB colony volume fraction and total surface area unit volume, and total surface area of individual PSBs per unit volume and three-dimensional angular orientation distribution of the PSBs. For this purpose, new stereological techniques have been developed for estimation of the three-dimensional angular orientation distribution. The stereological data reveal that during strain controlled in these AHSS steels, volume fraction of the PSB colonies varies linearly with the their total surface area per unit volume. Detailed analysis of the stereological data leads to a simple geometric model for evolution of the PSB colonies in the three AHSS steels, which accounts for all observed data trends.

Traditional approaches for power optimization during high level synthesis, have targetted single-cycle designs where only one input is being processed by the datapath at any given time. Throughput of large single-cycle designs can be improved by means of pipelining. In this work, we present a framework for the high-level synthesis of pipelined datapaths with low leakage power dissipation. We explore the effect of pipelining on the leakage power dissipation of data-flow intensive designs. An algorithm for minimization of leakage power during behavioral pipelining is presented. The transistor level leakage reduction technique employed here is based on Multi-Threshold CMOS (MTCMOS) technology. Pipelined allocation of functional units and registers is performed considering fixed data introduction intervals. Our algorithm uses simulated annealing to perform scheduling, allocation, and binding for obtaining pipelined datapaths that have low leakage dissipation.

Children with autism exhibit deficits in joint attention initiations, which are crucial to development of language and social skills (Bakeman & Adamson, 1984; Rollins, Wambacq, Mathews, & Reese, 1998; Whalen, Schreibman, & Ingersoll, 2006). Showing an object to a communication partner is an example of a joint attention initiation. A systematic synthesis of interventions targeting joint attention initiations was conducted to guide the development of an intervention for teaching showing behavior. In this study, a video modeling intervention was implemented with four young children with autism. Sessions were conducted during play sessions with the researcher in each participant’s typical therapy context. Following a prescribed baseline, the video modeling intervention was implemented. The video provided a model of an individual showing a toy to a communication partner with narration explaining the four components of the showing behavior: gaining the partner’s attention, making eye contact, extending the toy toward the partner, and commenting on the toy. Following the first four intervention sessions, verbal feedback and practice was added with the video model. The effects of this intervention on accuracy (percentage of components completed) and frequency of showing behavior and generalization to a small group setting with peers were evaluated using a multiple baseline across design across participants. Results indicate that accuracy and frequency of showing behavior increased when the video modeling intervention was implemented. The acquisition, performance, and generalization of showing behavior in relation to the video modeling intervention are discussed. Implications for teaching joint attention initiations and directions for future research are presented. / text

The retinoblastoma tumor suppressor protein (RB) is an important regulator of the cell cycle and development. Significantly, RB is inactivated in a majority of human cancers. Thus, elucidating the function of RB will give us a better understanding of how it prevents cancer. Many decades of research have yielded a detailed understanding of the role of RB in cell proliferation through transcriptional repression of target genes. However, the precise mechanisms of its action in many cellular pathways are poorly understood, including the control of DNA replication and post-transcriptional control of gene expression. Drosophila melanogaster presents a simplified genetic system to study cancer genes. Several published observations have suggested a role for RB in regulating DNA replication. Interestingly, other data indicate that RB associates with RNA processing factors. I have characterized novel protein-protein interactions with the Drosophila retinoblastoma tumor suppressor homologue Rbf, with an emphasis on its poorly characterized N-terminal domain. I describe the interaction of Rbf with the origin recognition complex, indicating a unique connection to DNA replication control. I also show that Rbf interacts with the RNA binding protein Squid, and review the literature that suggests potential role of RB/E2F in the control of RNA processing. The ability to control RNA processing may be an additional, unappreciated mode of gene regulation by RB. A focused study of the uncharacterized amino-terminal domain of Rbf has revealed new details about the retinoblastoma tumor suppressor in cell regulation, including DNA replication and RNA processing.

科学研究費補助金 研究種目:基盤研究(C) 課題番号:16570143 研究代表者:小川 徹 研究期間:2004-2005年度