Access to abstract permanently restricted to Ball State community only / Access to thesis permanently restricted to Ball State community only / School of Physical Education, Sport, and Exercise Science

Current knowledge indicates that nonthermal muscle metaboreflex activity plays a critical role in the modulation of skin vasodilation and sweating. However, the mechanisms of control have primarily been studied during isometric handgrip exercise in which muscle metaboreceptor activation is induced by a brief post-exercise ischemia of the upper limb. While the reflex increase in mean arterial pressure associated with this period of ischemia is consistent with the activation of muscle metaboreceptors, the change in baroreflex activity may in itself modulate the response. Thus, we sought to understand how these nonthermal stimuli interact in modulating the control of skin perfusion and sweating under conditions of elevated hyperthermia. Furthermore, we examined the mechanisms responsible for the maintenance of arterial blood pressure under varying levels of heat stress during isometric handgrip exercise. Our study findings indicate that the parallel activation of muscle metaboreceptors and baroreceptors during post-exercise ischemia causes divergent influences on the control of skin blood flow and sweating; and these nonthermal stimuli are dependent on the level of hyperthermia. Moreover, we report that heat stress reduces the increase in arterial blood pressure during isometric handgrip exercise and this attenuation is attributed to a blunted increase in peripheral resistance, since cardiac output increased to similar levels for all heat stress conditions. These results provide important insight and understanding into the role of muscle metabo- and baroreflex activity on the control of skin blood flow and sweating; along with further knowledge into the cardiovascular mechanisms responsible for the regulation of arterial blood pressure during hyperthermia.

名古屋大学博士学位論文 学位の種類 : 博士(医学)(論文) 学位授与年月日:平成8年7月12日 服部洋兒氏の博士論文として提出された

Thesis (M.A.)--University of Alabama at Birmingham, 2009. / Title from PDF title page (viewed Jan. 21, 2010). Includes bibliographical references (p. 47-53).

Thesis (Ph. D.)--University of Missouri--Columbia, 2002. / "December 2002." Typescript. Vita. Includes bibliographical references (leaves 141-160). Also issued on the Internet.

Abstract The core is the center of gravity in our body. Injuries and overload in the joints, is the most common reason for not be able to work in Sweden today. A god strength capacity in the core is important for secure and effective movements, as well for active athletes, as for non athletes. The increased number of employees, who report in sick today, has been correlated with psychological bad health. New methods to deal with mental and physical health problems among people can indicate to the fact that Yoga in the western world has increased its members, due its spiritual and physical recognition in favor of well being. The purpose with this study was to examine the effect of yoga practice on isometrics muscular strength endurance in the core, and if the mental and physical general health has been effected after 8 weeks of yoga classes twice a week. The method has a quantitative and qualitative approach. Fourteen health female subjects, ranging in age from 32 to 60 years old, were studied. The subjects were evaluated before and after the training program in three test positions for core isometric endurance. There was improvement for all the subjects, in all three tests positions together. The subject’s isometric endurance average improved with 29 %. All subjects reported improvement in physical and mental function after the yogic practices. These findings indicate that regular yoga practice can elicit improvements in isometric endurance in the core, and facilitate mental and physical well being for the subjects.

The American College of Sports Medicine (ACSM) currently recommends 1 set of 8 - 12 repetitions as the minimal dose of resistance training (RT) required to achieve the health and fitness benefits gained from RT. Yet, certain benefits derived from resistance training are not mentioned by the ACSM. An increase in basal metabolic rate (BMR) is a possible health benefit derived from RT. However, no previous studies have examined the effect of the ACSM's current resistance training recommendations on BMR. Therefore, the purpose of this study was to determine if this low level of RT could increase BMR in currently active older men. Sixteen subjects were assigned to either a training group or control group for 10 weeks of training. The training group continued their current aerobic activity while adding 1 set of RT 2x/week as recommended by the ACSM. The control group continued their aerobic activity with no modifications. Measurements of strength, fat free mass (FFM), and BMR were made pre- and posttraining. The training group showed an increase in strength (P<0.05) while the control group did not change. The training and control groups showed no change in FFM or BMR (P<0.05). The strength increases reported in the current study were of expected values while FFM and BMR have not been previously examined with this protocol. It was concluded that 10 weeks of RT using 1 set of 8 - 12 repetitions does not increase BMR in currently active older men. / School of Physical Education

The purpose of this study was to examine collegiate female swimmers' attitudes toward gender and coaching. The study also examined the coaching styles of male and females coaches and determined whether a difference between styles existed. A purposeful sample of 250 female swimmers from the Mid-American Conference (MAC) during the 2001-2002 swimming season participated in the study. Swimmers were required to have been coached by both female and male coaches in order to be eligible to participate. Addressing the purpose of this study, participants were asked to complete a 30-item questionnaire developed by the researcher. Frequency counts revealed that 23 of the 57 participants preferred a male coach to a female coach. Only two individuals reported their preference for a female with 32 participants citing no gender preference. Two sections, including 14 questions for each gender on the Gender Preference Instrument, assessed coaching style. Independent t -tests were calculated on each question (p < .05). Eight significant gender differences were observed on coaching styles, with the participating athletes scoring the male coach higher on all of the eight categories. / School of Physical Education

The Beothuk Indians were an extinct group of Amerinds who were among the earliest founders of Newfoundland. In literature, the Beothuk were described as perhaps being phenotypically more similar to Europeans than Asians (Gatschet 1890, Lloyd 1875, 1876a, Marshall 1996). In this research, mitochondrial DNA (mtDNA) analysis was performed on a Beothuk individual in order to determine his haplotype and, perhaps, shed light on the origins of the Beothuk.For this analysis, a tooth of Nonosabasut, a Beothuk chief who died in 1819 was loaned from the Royal Museum of Scotland. Ancient DNA was extracted from 172 mg of dentin from the tooth. The DNA was cut with two blunt-end restriction enzymes, RsaI and HaeIII. Double-stranded DNA adapters were ligated to the blunt ends. A single adapter was used to amplify the resulting fragments using PCR. In this manner, two libraries of the DNA were created that could be readily reamplified using a small amount of the PCR product. mtDNA type was determined by amplifying specific regions and performing Restriction Fragment Length Polymorphism analysis and sequencing. It was determined that the Beothuk individual had a 9-bp deletion at nucleotide position (np) 8272, an Alul restriction site at np 5176, and heteroplasmy for a HincII restriction site at np 13,259, indicating that the Beothuk individual falls into the Native American Haplogroup B. Haplogroup B is not present in modern Siberian populations, whereas the remaining Native American mtDNA haplogroups are. It has been hypothesized that Haplogroup B arrived in the Americas at a different time than haplogroups A, C, D, and X, about 16,000-13,000 YBP (Years Before Present) (Starikovskaya et al. 1998). Haplogroup B can be found in some modern Taiwanese, Japanese, Korean, Evenk, and other Asian populations.Sequencing of the D-Loop region revealed a G to A transition at np 16303. To our knowledge, this transition was never previously reported in a Native American. This transition has been reported in Tibetans, Koreans, Hans, and Japanese, all considered to be southeast Asian Causacoids (Torroni et al. 1993b, 1994b). This transition, also frequently described in the Caucasian Haplogroup H, is especially prevalent in Spain and among the Basque. It is described as a root haplotype of Haplogroup H whose expansion was estimated to be between 12,300-13,200 YBP (Torroni et al. 1998). This time estimate coincides with the expansion of Haplogroup B. One possible explanation for this transition may be some admixture of the Beothuk with a Caucasian population. / School of Physical Education

Cyclooxygenase (COX) is the enzyme that catalyzes the rate-limiting step in prostaglandin (PG) synthesis. In skeletal muscle, PGF2a, has been shown to regulate protein synthesis, and ibuprofen and acetaminophen have been shown to block the normal increase in PGF2a and muscle protein synthesis following resistance exercise in humans. The purpose of this investigation was to determine the expression of the COX-1 (COX-1 variants: COX-1 v1, -1v2, -1 b,, -1 b2, and -1b3) and COX-2 isoforms following resistance exercise to help elucidate the isoform or variant through which PGF2a, ibuprofen, and acetaminophen regulate muscle protein synthesis. Human skeletal muscle biopsy samples were taken from 16 individuals (8M, 8F) before, 4 h, and 24 h following a single bout of resistance exercise and analyzed using real-time RT-PCR. COX-Iv1 and COX-1v2 were the most abundant COX mRNA before exercise and remained unchanged (P>0.05) following exercise (i.e., constitutively expressed). Relatively few individuals expressed the intron 1-retaining COX-1 b variants (COX-1 b,, - 1b2, and -1 b3) at any time point, and when expressed these variants were in very low abundance. COX-2 was not expressed in any subject before exercise, but increased significantly (P<0.05) at 4 and 24 h following exercise. These results suggest that the intron 1-retaining COX-1 b,, -1 b2, and -lb3 variants are likely not the COX through which PGF2a is produced to stimulate skeletal muscle protein synthesis. PGF2a, stimulation, as well as ibuprofen and acetaminophen inhibition of skeletal muscle protein synthesis likely work through COX-2, or one of the constitutively expressed COX-1 variants (COX-lv1 or -1v2). / School of Physical Education, Sport, and Exercise Science