Made available in DSpace on 2014-12-17T15:32:16Z (GMT). No. of bitstreams: 1 DeborahPPI.pdf: 1504501 bytes, checksum: a7d060d1016a25d3b60f572c27bd03bc (MD5) Previous issue date: 2008-10-14 / We investigated the immunohistochemistry expression of claudins -1 and -7 in ameloblastoma and in human dental germs on the pattern of distribution (focal, regional or diffuse), the cells that expressed (if central or peripheral) and the location of that expression in the cell components recital membrane, cytoplasm and nucleus. Among the 29 cases of ameloblastoma, 24 were type solid and 6 unicystic. In 7 mandibular specimens of human fetuses found dental germs from the stage of bud to the crown. We note that the pattern of expression in the dental germs was variable for claudinas studied according to the cell type and stage of differentiation and was invariate only in the cells of stellate reticulum. In epithelium internal of enamel organ, claudin-1 has been decreasing with the progression of differentiation as to claudina-7 that was found in the cells of the peripheral papilla. For ameloblastoma the expression was more significant than that observed in dental germs. Fisher s exact test no found association between the expression of claudinas cells in central and peripheral and the type of ameloblastoma (solid or unicystic). Thus, in general the claudin-1 was positive in the central cell of 93,1% of the cases and in peripheral cells of 51,7%. The claudin-7 was expressed in the cells of all cases central and peripheral cells from 89,7%. For both claudins the distribution was predominantly diffuse cells both in central and peripheral cells. Given our findings it is suggested that the expression of claudins may be indicative of the involvement of these molecules in morphogenetics events culminating with the dental development and that possibly influence the development of neoplastic ameloblastoma / Investigamos a express?o imuno-histoqu?mica das claudinas -1 e -7 em ameloblastomas e germes dentais humanos, avaliando o padr?o de distribui??o (focal, regional ou difuso), as c?lulas que as expressavam (central ou perif?rica) e a localiza??o dessa express?o nos constituintes celulares considerando membrana, citoplasma e n?cleo. Dentre os 29 casos de ameloblastomas, 23 eram do tipo s?lido e 6 unic?sticos. Nos 7 esp?cimes mandibulares de fetos humanos observamos germes dentais desde a fase de capuz at? a fase de coroa. Constatamos que o padr?o de express?o nos germes dentais foi vari?vel para as claudinas estudadas de acordo com o tipo celular e est?gio de diferencia??o assemelhando-se apenas nas c?lulas do ret?culo estrelado. No epit?lio interno a express?o da claudina-1 foi decrescente com a progress?o da diferencia??o enquanto para a claudina-7 foi verificada nas c?lulas perif?ricas da papila. Para os ameloblastomas, de forma geral, a express?o foi mais significativa do que aquela observada nos germes dentais. Foi aplicado o teste estat?stico de Fisher o qual n?o demonstrou associa??o entre a express?o das claudinas nas c?lulas centrais e perif?ricas e o tipo do ameloblastoma (s?lido ou unic?stico). De uma maneira geral, a claudina-1 foi positiva nas c?lulas centrais de 93,1% dos casos e nas c?lulas perif?ricas de 51,7%. A claudina-7 esteve expressa nas c?lulas centrais de todos os casos e nas c?lulas perif?ricas de 89,7%. Para ambas as claudinas a distribui??o foi predominantemente difusa tanto nas c?lulas centrais como nas c?lulas perif?ricas. Diante dos nossos achados sugere-se que a express?o das claudinas pode ser indicativa da participa??o destas mol?culas nos eventos morfogen?ticos que culminam com a forma??o dental e possivelmente influenciam o desenvolvimento neopl?sico dos ameloblastomas

Made available in DSpace on 2015-03-03T15:28:33Z (GMT). No. of bitstreams: 1 ElvisSS_DISSERT.pdf: 714691 bytes, checksum: 14d53d32eb67e048150da6da7ea2ee1d (MD5) Previous issue date: 2012-07-20 / This paper proposes a new control chart to monitor a process mean employing a combined npx-X control chart. Basically the procedure consists of splitting the sample of size n into two sub-samples n1 and n2 determined by an optimization search. The sampling occur in two-stages. In the first stage the units of the sub-sample n1 are evaluated by attributes and plotted in npx control chart. If this chart signs then units of second sub-sample are measured and the monitored statistic plotted in X control chart (second stage). If both control charts sign then the process is stopped for adjustment. The possibility of non-inspection in all n items may promote a reduction not only in the cost but also the time spent to examine the sampled items. Performances of the current proposal, individual X and npx control charts are compared. In this study the proposed procedure presents many competitive options for the X control chart for a sample size n and a shift from the target mean. The average time to sign (ATS) of the current proposal lower than the values calculated from an individual X control chart points out that the combined control chart is an efficient tool in monitoring process mean. / Esta disserta??o prop?e um novo gr?fico (ou procedimento) de controle para monitorar a centralidade de um processo (m?dia) por meio da jun??o dos gr?ficos X e npx. Basicamente o procedimento consiste em dividir a amostra de tamanho n em duas (n1 e n2), definidas pelo processo de otimiza??o. Realiza-se a amostragem em dois est?gios. No primeiro est?gio conta-se o n?mero de itens n?o conformes amostra de tamanho n1 por meio do gr?fico npx. Caso haja um n?mero excessivo de itens n?o conformes, segue-se para o segundo est?gio da amostragem, onde calcula-se a m?dia X da amostra de tamanho n2. A possibilidade de n?o inspecionar todos os itens reduz tanto o custo quanto o tempo gasto para inspecionar os itens da amostra. Descreve-se a metodologia de constru??o, avalia??o e o funcionamento do gr?fico aqui proposto, e com o aux?lio do software estat?stico Rc e feito um estudo comparativo entre os gr?ficos individuais X e npx e o gr?fico misto. Neste estudo verificou-se que o procedimento proposto fornece v?rias op??es concorrentes com o gr?fico X para um dado tamanho de amostra n e um desvio na m?dia . Os valores do tempo esperado at? o sinal (TES) inferiores aos provenientes do gr?fico individual X evidenciaram que o gr?fico misto ? uma ferramenta eficaz no monitoramento de processos capaz de substituir o gr?fico da m?dia

Submitted by Automa??o e Estat?stica (sst@bczm.ufrn.br) on 2017-02-09T21:43:59Z No. of bitstreams: 1 WellingtonVieiraMendes_TESE.pdf: 2621241 bytes, checksum: f6a95e3bc3e71ca27b84f76bdb210ccf (MD5) / Approved for entry into archive by Arlan Eloi Leite Silva (eloihistoriador@yahoo.com.br) on 2017-02-10T17:04:04Z (GMT) No. of bitstreams: 1 WellingtonVieiraMendes_TESE.pdf: 2621241 bytes, checksum: f6a95e3bc3e71ca27b84f76bdb210ccf (MD5) / Made available in DSpace on 2017-02-10T17:04:04Z (GMT). No. of bitstreams: 1 WellingtonVieiraMendes_TESE.pdf: 2621241 bytes, checksum: f6a95e3bc3e71ca27b84f76bdb210ccf (MD5) Previous issue date: 2016-08-22 / Coordena??o de Aperfei?oamento de Pessoal de N?vel Superior (CAPES) / A observa??o do modo como se organizam os textos acad?micos permite o entendimento dos mecanismos de constru??o dos sentidos nos diferentes estratos dos sistemas discursivos. Al?m das caracter?sticas lexicogramaticais que se configuram na superf?cie dos textos, o reconhecimento dos contextos em que s?o produzidos possibilita tamb?m compreend?-los como sendo resultantes de processos de constru??o de sentidos complexos e articulados nesses sistemas, tal como definido pela Lingu?stica Sist?mico-Funcional (LSF). Este estudo se filia aos modelos de sistemas discursivos propostos por Martin e Rose (2007), aos estudos de coes?o desenvolvidos em Halliday e Hasan (1976) e ? gram?tica sist?mico-funcional de Halliday e Matthiessen (2014). O foco e escopo do trabalho ? o fen?meno da jun??o com marcadores expl?citos ? aqui concebida como diferentes realiza??es da lexicogram?tica que, independentemente de seu estatuto ou extens?o, atuam na conflu?ncia de complexos oracionais. Neste caso espec?fico, o interesse se volta aos textos produzidos por graduandos e p?s-graduandos em Letras, a fim de: (i) identificar as rela??es de jun??o em textos acad?mico-cient?ficos produzidos por estudantes de gradua??o e de p?s-gradua??o; (ii) comparar os usos das rela??es de jun??o entre os textos produzidos por estudantes de gradua??o e p?s-gradua??o; (iii) apresentar contribui??es para as pr?ticas de escrita na academia a partir dos subs?dios te?ricos fornecidos pela LSF sobre articula??o textual. Para atendimento destes objetivos, a pesquisa analisa um corpus de 9,8 milh?es de palavras composto por artigos, monografias, disserta??es e teses da ?rea de Lingu?stica. Os dados foram recenseados com apoio de ferramentas dispon?veis nas aplica??es do WordSmith Tools (SCOTT, 2012), especificamente no tratamento quantitativo de amostras. ? guisa de resultados, ? poss?vel indicar que a jun??o com marcador expl?cito se situa com maior recorr?ncia nos textos de graduandos, mas colabora, indistintamente nos trabalhos de gradua??o e p?s-gradua??o, para a constru??o de sentidos no discurso porque configuram rela??es e atividades dentro do pr?prio texto e para al?m dele, tanto pelas passagens argumentativas de um t?pico a outro, como pelo emprego de recursos como met?frase, transposi??o e/ou amplia??o de sentidos quando esses componentes funcionais apontam para a experi?ncia ou idea??o e, noutros casos, para a organiza??o sequencial do texto. / The observation of how academic texts are organized provides the understanding of the meaning construction mechanisms in the different strata of the discursive systems. Besides the lexicogrammatical characteristics which configure on the surface of the texts, the contexts recognition in which they are produced also make it possible to understand them as a result of a complex process of meaning construction and articulated in these systems according to Systemic Functional Linguistics (SFL). The theoretical frameworks of this study are the discursive system model suggested by Martin and Rose (2007), the cohesion studies carried out by Halliday and Hasan (1976) and the Systemic-Functional Grammar by Halliday and Matthiessen (2014). The focus and objective of this research is the junction phenomenon with overt markers - here conceived as different lexicogrammatical realizations which, regardless their status or length, act in the confluence of clause complexes. In this specific case, the focus is shifted towards texts written by Letras undergraduate and graduate students. It aims at: (i) Identifying the relations of junction in academic texts written by undergraduate and graduate students; (ii) comparing the usages of relation of junctions within the texts written by undergraduate and graduate students; (iii) provide input to writing practices in the gym from the theoretical basis provided by LSF on textual articulation. To reach these objectives, the research analyzes a corpus of 9,8 million words composed of research articles, monographs, master?s dissertations and doctoral theses in Linguistics. The data were compiled with the support of the tools available for use on WordSmith Tools (SCOTT, 2012), specifically on the quantitative treatment of the samples. By way of results, it is possible to state that junction with overt marker shows a higher recurrence in the undergraduates? texts, but cooperate, indistinctly, with the undergraduates? and graduates? works, for the meaning construction in discourse because they configure relations and activities in the text itself and beyond, as much for the argumentative passages of a given topic or another, as for the usage of resources such as metaphrase, transposition and/or amplification of meanings when these functional components point out towards the experience or ideation and, in other cases, for the sequential organization of the text.

Made available in DSpace on 2014-12-17T14:08:54Z (GMT). No. of bitstreams: 1 ItaloBS_DISSERT_Parcial.pdf: 1092449 bytes, checksum: 84033c6935995f4df8913ea7b715a8e5 (MD5) Previous issue date: 2014-01-16 / The study of complex systems has become a prestigious area of science, although relatively young . Its importance was demonstrated by the diversity of applications that several studies have already provided to various fields such as biology , economics and Climatology . In physics , the approach of complex systems is creating paradigms that influence markedly the new methods , bringing to Statistical Physics problems macroscopic level no longer restricted to classical studies such as those of thermodynamics . The present work aims to make a comparison and verification of statistical data on clusters of profiles Sonic ( DT ) , Gamma Ray ( GR ) , induction ( ILD ) , neutron ( NPHI ) and density ( RHOB ) to be physical measured quantities during exploratory drilling of fundamental importance to locate , identify and characterize oil reservoirs . Software were used : Statistica , Matlab R2006a , Origin 6.1 and Fortran for comparison and verification of the data profiles of oil wells ceded the field Namorado School by ANP ( National Petroleum Agency ) . It was possible to demonstrate the importance of the DFA method and that it proved quite satisfactory in that work, coming to the conclusion that the data H ( Hurst exponent ) produce spatial data with greater congestion . Therefore , we find that it is possible to find spatial pattern using the Hurst coefficient . The profiles of 56 wells have confirmed the existence of spatial patterns of Hurst exponents , ie parameter B. The profile does not directly assessed catalogs verification of geological lithology , but reveals a non-random spatial distribution / O estudo dos sistemas complexos tornou-se uma ?rea prestigiada da ci?ncia, apesar de ser relativamente jovem. Sua import?ncia foi comprovada pela diversidade de aplica??es que v?rios estudos j? proporcionaram para campos diversos como os da Biologia, Economia e Climatologia. Na F?sica, a abordagem dos sistemas complexos vem criando paradigmas que influenciam de forma marcante os novos m?todos, trazendo para a F?sica Estat?stica problemas de n?vel macrosc?pico n?o mais restritos a estudos cl?ssicos como os da Termodin?mica. O presente trabalho tem como objetivo fazer uma compara??o e verifica??o dos aglomerados estat?sticos de dados relativos aos perfis de S?nico (DT), Raio Gama (GR), Indu??o (ILD), Neutr?nico (NPHI) e Densidade (RHOB) por serem grandezas f?sicas medidas durante a perfura??o de po?os explorat?rios de fundamental import?ncia para localizar, identificar e caracterizar reservat?rios de petr?leo. Foram utilizados os softwares: Statistica, Matlab R2006a, Origin 6.1 e Fortran para a compara??o e verifica??o dos dados dos perfis de po?os de petr?leo da Escola Campo Namorado cedidos pela ANP (Ag?ncia nacional de petr?leo). Foi poss?vel evidenciar a import?ncia do m?todo DFA e que o mesmo mostrou-se bastante satisfat?rio no referido trabalho, chegando-se a conclus?o que os dados do H (expoente de Hurst) produzem dados espaciais com uma maior aglomera??o. Portanto, constatamos que ? poss?vel encontrar padr?o espacial usando o coeficiente de Hurst. Os perfis dos 56 po?os comprovaram a exist?ncia de padr?es espaciais dos expoentes de Hurst, ou seja, par?metro B. O perfil avaliado n?o cataloga diretamente a verifica??o da litologia geol?gica, mas revela a exist?ncia de uma distribui??o espacial n?o aleat?ria / 2024-12-31