This report describes the project background, design process plus the final result of my MFA degree thesis in Advanced Product Design at Umeå Institute of Design. A breast pump is generally a mechanical or electrical suction device for withdrawing milk from the breast of a lactating woman. Even though the first pumps were patented in the mid-19th century as medical devices for in-hospital use, breast pumps as widely available consumer products have only been around for a little more than 20 years. Existing breast pumps do not address functional as well as emotional needs of many mothers and there is great potential for improvements and innovative solutions to transform pumping into a more enjoyable and positively associated experience. The main purpose of this project is to rethink the way breast pumps are currently used in order to push the boundaries, and come up with a forward-looking, conceptual design solution as a final result. This human-centered design project was carried out in close collaboration with various experts in the areas of pediatrics, breastfeeding and lactation counselling. Moreover this project was done in cooperation with leading design and innovation consulting firm IDEO. San Francisco basted design director Thomas Overthun provided mentoring throughout the design process. Regular check-in calls and feedback sessions were set up throughout the project to discuss project milestones. Anders Smith, an experienced industrial designer from Denmark, closely followed throughout the project as an external design tutor at Umeå Institute of Design. Several tutoring sessions were held on a regular basis. Continuous involvement of experts and external project advisors helped to make sure that the project remains valid and provided a great source for relevant insights, expert knowledge and professional feedback. "Being able to develop an impactful and forward-looking design solution that can encourage positive change both on an individual and societal level has been my main motivation to tackle this design challenge".

Submitted by Biblioteca da Faculdade de Farmácia (bff@ndc.uff.br) on 2017-03-28T18:39:00Z No. of bitstreams: 1 Pereira, Tatiane Aguiar Durães [Dissertação, 2014].pdf: 1735158 bytes, checksum: a682bc5c3ae743230efe452e23a93bb2 (MD5) / Made available in DSpace on 2017-03-28T18:39:00Z (GMT). No. of bitstreams: 1 Pereira, Tatiane Aguiar Durães [Dissertação, 2014].pdf: 1735158 bytes, checksum: a682bc5c3ae743230efe452e23a93bb2 (MD5) / Introdução: Sabe-se que o leite humano contém não apenas macro e micronutrientes, mas também uma variedade de substâncias bioativas, tais como os hormônios, grelina e leptina. A leptina principalmente sintetizada pelo tecido adiposo promove a saciedade e é liberado na corrente sanguínea proporcionalmente a quantidade de massa de gordura corporal. A grelina é sintetizada essencialmente no estômago, sendo conhecida como “hormônio da fome”, estimulando a ingestão de alimentos. A leptina e a grelina sofrem influências de outros hormônios, como a prolactina, dependendo do momento metabólico da mulher, modificando seu mecanismo de ação normal, durante a lactação, seus níveis podem estar diminuídos. Esses hormônios estão presentes no leite materno e passam para o lactente podendo influenciar seu desenvolvimento. Dessa maneira, o objetivo desse estudo foi determinar a concentração de leptina e grelina no sangue e leite materno (LM) e avaliar a relação com o estado nutricional da nutriz e do lactente. Metodologia: Trata-se de um estudo analítico observacional longitudinal, com 40 nutrizes e seus lactentes, em aleitamento materno exclusivo ou predominante, avaliados em 3 momentos, 30, 60 e 90 dias pós-parto. Os hormônios foram analisados pelométodo ELISA. Resultados: O peso, índice de massa corporal (IMC) e percentual de gordura corporal (PGC) das nutrizes apresentaram-se semelhantes ao longo do estudo, não houve perda de peso corporal, mas sim retenção de 7,1±2,3Kg e aumento de 3% PGC, ocorrendo uma transição no perfil nutricional. Quanto aos lactentes, o peso, perímetro cefálico e comprimento, apresentaram-se diferentes (p<0,0001) daquele ao nascimento, apresentaram crescimento ascendente, porém, acima do esperado para o trimestre (3102±930,9g). No decorrer da lactação, os níveis hormonais analisados não se modificaram. Foram encontradas maiores concentrações (p<0,0001) de leptina e grelina no plasma, em relação ao leite materno. A leptina do plasma associou-se de forma positiva com os níveis de leptina do LM (r=0,78; p=0,01), e também com a antropometria materna (IMC aos 90 PP e PGC aos 30 e 90 PP) e negativamente com o ganho de peso do lactente (r= -0,64; p=0,04). A grelina associou-se de forma negativa com o perímetro cefálico do lactente (r=-0,57; p=0,03) e com o peso da nutriz (r=-0,66; p=0,03). Conclusão: As nutrizes no primeiro trimestre pós-parto apresentaram aumento da gordura corporal e retenção de peso. Os lactentes apresentaram ganho de peso excessivo nesse período e podem sofrer influências da composição corporal materna e hormonais. Os níveis de leptina e grelina foram maiores no plasma e ambos podem influenciar a antropometria materna e do lactente, além disso, seus níveis podem sofrer influências hormonais, como da prolactina, que pode contribuir para o controle da ingestão alimentar das nutrizes, nesse período / Introduction: It is known that human milk contains not only macronutrients and micronutrients, but also a variety of bioactive substances, such as hormones, ghrelin and leptin . Leptin mainly synthesized by adipose tissue promotes satiety and is released into the bloodstream in proportion to amount of body fat mass. Ghrelin is synthesized primarily in the stomach, known as the " hunger hormone " , stimulating food intake. Leptin and ghrelin are influenced by other hormones, such as prolactin, modifying its normal mechanism of action depending on the time of metabolic woman, their levels may be reduced during lactation. These hormones are present in breast milk and can pass to the infant and influence its development. Thus, the objective of this study was to determine the concentration of leptin and ghrelin in the blood and breast milk (BM) and evaluate its relationship to the nutritional status of the lactating woman and infant. Methodology: This is a longitudinal observational analytic study with 40 lactating woman and their infants exclusively or predominantly breastfed, valued at 3 times: 30, 60 and 90 days postpartum. The hormones were analyzed by ELISA. Results: The weight, body mass index (BMI) and body fat percentage (BFP) of the mothers were similar throughout the study, there was no weight loss, but retention of 7.1 ± 2.3 kg and 3% increase in BFP, a transition occurring in the nutritional profile. About infants, weight, head circumference and length, showed up different (p < 0.0001) at birth, showed normal growth, higher than expected for the period (3102 ± 930.9g). During lactation, hormone levels analyzed were unchanged. Higher concentrations (p < 0.0001) of the plasma leptin and ghrelin, relative to the milk were found. The plasma leptin was associated positively with leptin levels of BM (r = 0.78, p = 0.01), and also with maternal anthropometry (BMI 90 to PP and BFP at 30 and 90 PP), and negatively associated with infant weight gain (r = -0.64, p = 0.04). Ghrelin, was associated negatively with infant head circumference (r = -0.57, p = 0,03) and the weight of the lactating woman (r = -0.66, p = 0.03). Conclusion: Lactating woman in the first postpartum trimester showed increased body fat and weight retention. The infants showed excessive weight gain during this period and can be influenced maternal hormonal and body composition. The levels of leptin and ghrelin were higher in plasma, and both can influence maternal and infant anthropometry, moreover, their levels may suffer hormonal influences, such as prolactin, which may contribute to the control of food intake of the mothers, in this period

Breastfeeding is at its best when both the mother and infant benefit from the experience. Aim: To obtain data on the adequacy of the diet and nutrition knowledge of lactating women (0-6 months postpartum) living in a low socio-economic area in Nairobi. The findings could be used to plan future nutrition intervention programs. Research design: A cross-sectional survey in the quantitative and qualitative research paradigms. Health status indicators, socio-economic and cultural factors were additionally investigated as interactive factors that could influence the nutrient intake and nutrition knowledge of the lactating women. Setting: Mbagathi District Hospital, located at the edge of Kibera slum area in Nairobi. Sample: Lactating mothers (0-6 months postpartum), who were visiting the Maternal-Child Health Clinic to bring their children for immunisation, were recruited. Convenience sampling was used (N=120). Informed consent was obtained from the mothers in their home tongue. Methodology: Individual interviews in Swahili, using structured questionnaires (Socio biodemographic questionnaire, Hunger Scale, 24 Hour-recall, and Quantitative Food Frequency Questionnaire), and anthropometry (according to standard procedure) were done in the quantitative domain. Seven structured focus group discussions were employed in the qualitative domain. Descriptive and inferential statistics were used on the quantitative data, and Krueger‘s framework of analysis on the qualitative data. Ethical approval was obtained from the Ethics Committee, Faculty of Natural and Agricultural Sciences, University of Pretoria; Ref no EC 080922-039, and research permission was granted by the National Council for Science and Technology, Nairobi; Permit no NCST/5/002/R/355. Main findings: Majority of women (92%) had energy intakes between 5040 – 10080 kJ/day with the mean energy intake of 6975.5 kJ/day which was lower than the recommended 11340 kJ/day. Macronutrient intake was within the acceptable macronutrient distribution ranges, whereas the micronutrients were consumed below the recommended dietary allowances (WHO). The mean adequacy ratio (excluding niacin) was 0.74. The highest frequency of consumption (100%) was from cereals, while the lowest were for vitamin A rich vegetables/fruits (6.6%) and dairy products (1.7%). Overall, the mean Food Variety Score (FVS) was 6.6 ( ± 2.0) and the Dietary Diversity Score (DDS) was 4.3 ( ± 1.0). Hunger assessment revealed 43 households that were food secure, whereas 77 households were either hungry or at risk of hunger. Majority of women (93%) had good nutrition knowledge but the rationale for applying the knowledge was lacking for most of the nutrition concepts. Socio-economic status, cultural beliefs and practices, health status and nutrition knowledge were all identified as probable factors that influenced the dietary intake of the lactating women. Recommendation: There seems to be a need for well-designed nutrition intervention programs focusing on nutrient intake from culturally acceptable and affordable foods to increase dietary diversity and food variety of lactating women in this low socio-economic area. With a concurrent increase in nutrition knowledge such interventions would improve their nutritional status. / Dissertation (MSc)--University of Pretoria, 2010. / Food Science / unrestricted