Global ETD Search

1	Efeitos da velocidade de recirculação em reator de biofilme aerado em membranas em batelada sequencial na remoção de nutrientes e carbono orgânico de esgoto doméstico / Silva, Tatiana Santos da. January 2017 (has links) Orientador: Tsunao Matsumoto / Resumo: A aplicação do Reator de Biofilme Aerado em Membrana (MABR) no tratamento de esgotos apresenta como desafio o controle da espessura ótima do biofilme uma vez que elevadas espessuras impedem a transferência de oxigênio e de substratos paras as camadas que compõem o biofilme, findando no decaimento do desempenho do MABR. O objetivo central deste trabalho foi analisar o efeito da velocidade de recirculação sobre a eficiência de remoção de nutrientes e carbono orgânico, em um MABR operado em batelada sequencial com esgoto doméstico bruto. Com um volume de 20 L, o MABR continha um módulo de membranas com 0,08 m2m-3 de área específica, operando com ciclo de batelada de 12 horas. Foram monitorados os seguintes parâmetros: pH, temperatura, oxigênio dissolvido, nitrogênio amoniacal, nitrogênio total, nitrato, nitrito, DQO, fósforo e SSV. A taxa de remoção de amônia alcançada foi de até 75,17% e 62,5% na remoção de Nitrogênio Total para a velocidade de 11 cm/s. Nesta pesquisa houve pouca remoção do fósforo. Na remoção de carbono orgânico foram alcançadas eficiências em torno de 80% nas velocidades de recirculação de 6,3 e 11 cm/s. Assim, a melhor velocidade de recirculação para operação do MABR nas condições apresentadas neste trabalho, seria uma velocidade intermediária a 6,3 e 11 cm/s, na qual ocorreriam tanto a nitrificação e desnitrificação, pela permanência da camada anóxica, e a oxidação pelas heterótrofas. / Mestre MABR Nitrificação. Desnitrificação Remoção de DQO Reator em batelada Biofilme aerado
2	Efeitos da velocidade de recirculação em reator de biofilme aerado em membranas em batelada sequencial na remoção de nutrientes e carbono orgânico de esgoto doméstico / Effects of recirculation speed in membrane aerated biofilm reactor in sequencial battle in the removal of nutrients and organic carbon of domestic sewage Silva, Tatiana Santos da [UNESP] 02 March 2017 (has links) Submitted by Tatiana Santos da Silva null (tatianaengambiental@gmail.com) on 2017-04-27T16:58:43Z No. of bitstreams: 1 2017_Tatiana Santos da Silva.pdf: 2674148 bytes, checksum: 550a2730ada1290262c2c460de534577 (MD5) / Approved for entry into archive by Juliano Benedito Ferreira (julianoferreira@reitoria.unesp.br) on 2017-05-02T17:11:53Z (GMT) No. of bitstreams: 1 silva_ts_me_ilha.pdf: 2674148 bytes, checksum: 550a2730ada1290262c2c460de534577 (MD5) / Made available in DSpace on 2017-05-02T17:11:53Z (GMT). No. of bitstreams: 1 silva_ts_me_ilha.pdf: 2674148 bytes, checksum: 550a2730ada1290262c2c460de534577 (MD5) Previous issue date: 2017-03-02 / A aplicação do Reator de Biofilme Aerado em Membrana (MABR) no tratamento de esgotos apresenta como desafio o controle da espessura ótima do biofilme uma vez que elevadas espessuras impedem a transferência de oxigênio e de substratos paras as camadas que compõem o biofilme, findando no decaimento do desempenho do MABR. O objetivo central deste trabalho foi analisar o efeito da velocidade de recirculação sobre a eficiência de remoção de nutrientes e carbono orgânico, em um MABR operado em batelada sequencial com esgoto doméstico bruto. Com um volume de 20 L, o MABR continha um módulo de membranas com 0,08 m2m-3 de área específica, operando com ciclo de batelada de 12 horas. Foram monitorados os seguintes parâmetros: pH, temperatura, oxigênio dissolvido, nitrogênio amoniacal, nitrogênio total, nitrato, nitrito, DQO, fósforo e SSV. A taxa de remoção de amônia alcançada foi de até 75,17% e 62,5% na remoção de Nitrogênio Total para a velocidade de 11 cm/s. Nesta pesquisa houve pouca remoção do fósforo. Na remoção de carbono orgânico foram alcançadas eficiências em torno de 80% nas velocidades de recirculação de 6,3 e 11 cm/s. Assim, a melhor velocidade de recirculação para operação do MABR nas condições apresentadas neste trabalho, seria uma velocidade intermediária a 6,3 e 11 cm/s, na qual ocorreriam tanto a nitrificação e desnitrificação, pela permanência da camada anóxica, e a oxidação pelas heterótrofas. MABR Nitrificação Desnitrificação Remoção de DQO Reator em batelada Biofilme aerado
3	Structural analysis of transcription factors involved in Mycobacterium tuberculosis mycolic acid biosynthesis Tanina, ABDALKARIM 10 July 2020 (has links) (PDF) Tuberculosis (TB) remains the leading cause of death due to a single infectious agent with more than 1.5 million people killed each year. In 2018, the World Health Organization (WHO) estimated that one third of the world’s population was infected with Mycobacterium tuberculosis (Mtb), the pathogen responsible for the disease.In 2000, EthR, a mycobacterial transcriptional repressor, was identified as a key modulator of ethionamide (ETH) bioactivation. ETH is one of the main second-line drugs used to treat drug-resistant strains and it is a prodrug that is activated in Mtb by the mono-oxygenase EthA and then inhibits InhA, an enzyme involved in the mycolic acid biosynthesis. In 2009, it was demonstrated that co-administration of ETH with the drug-like inhibitors of EthR was able to boost ETH activity by a factor three in a mouse-model of TB-infection, thus validating EthR protein as a target for a new therapeutic strategy. The first part of this thesis deals with the validation and deep characterization of the solved EthR-ligand structures based on all analysis of how each ligand bind to the EthR. In this section, based on the study of both co-crystal structures and the physicochemical properties of the ligands, we have rationalized the information currently available and understood the interaction of all EthR inhibitors in order to lead to more effective inhibitor design.More recently, another mycobaterial repressor, denoted EthR2, was identified as a putative target that appears to be functionally comparable to EthR (then the locus has been termed EthA2/EthR2, due to its similarity to the EthA/EthR locus). Furthermore, a spiroisoxazoline family of small-molecules, generically denoted as SMARt, has been identified as effective ligand of EthR2. However, according to the data present in the literature, this spiroisoxazoline family can also bind to the former EthR. In order to investigate this proposition, I have solved these small molecules in complex with EthR and compared their binding interactions to the EthR2 protein as well. The opportunity for the design small-molecules is capable of targeting both repressors, thereby opening the way to a dual-target approach.Finally, the third part of this thesis is devoted to the mycobacterial transcriptional factor MabR (Rv2242). Several studies identified this protein as a regulatory transcription factor of the fatty acid synthase II operon, which is mainly responsible for the mycolic acid biosynthesis in Mtb. I therefore purified to homogeneity and characterized the MabR protein as well as I determined the crystal structure of its C-terminal part. Finally, the functional role of MabR is largely discussed, and the way on how to interfere with its DNA binding ability is commented with respect to our results. / Doctorat en Sciences biomédicales et pharmaceutiques (Pharmacie) / info:eu-repo/semantics/nonPublished Sciences bio-médicales et agricoles
4	Feasibility of sustainable nitrogen removal: integration of partial nitritation-anammox with membrane aerated biofilm reactor (MABR) Shiu, Natalia January 2023 (has links) The presence of nutrients, such as nitrogenous compounds, in wastewater can pose serious environmental concerns to water systems leading to reduced water quality and potential risks to the public health. Nutrient removal in conventional wastewater treatment systems is becoming increasingly more costly due to the extensive energy requirements and high aeration costs. Anaerobic ammonium oxidation (Anammox) is an alternative method for nutrient removal which can reduce overall treatment costs due to less aeration requirements and less sludge production. Anammox process can be implemented with other innovative technologies, such as membrane aerated biofilm reactors (MABR) to achieve effective and sustainable nutrient removal. A major challenge associated with Anammox process is effective control of nitrite oxidizing bacteria (NOB). High temperature in wastewater treatment systems can promote Anammox bacterial growth and inhibit NOB activity. This research aims to investigate the feasibility of integrating Anammox processes with MABR technologies and to examine the effects of high temperature aeration supplied to MABR systems on Anammox bacterial growth and NOB suppression. The nitrogen removal by Anammox bacteria in a lab-scaled MABR is examined to determine the impact of aeration temperature on inhibition of NOB. / Thesis / Master of Applied Science (MASc) anaerobic ammonium oxidation (anammox) membrane aerated biofilm reactor (MABR) sustainable nitrogen removal
5	Collaborating in the electric age: [onto]Riffological experiments in posthumanizing education and theorizing a machinic arts-based research Stevens, Shannon Rae 05 February 2021 (has links) Collaborating in the Electric Age: [onto]Riffological Experiments in Posthumanizing Education and Theorizing a Machinic Arts-Based Research is a study about locating opportunities and entry points for introducing consideration of the nonhuman and posthuman to pedagogical perspectives that are traditionally concerned with human beings and epistemological subjects. The research, herein, engages doings in collaborative effort, during conditions of unprecedented interconnectedness facilitated by the electric age. Steeped in a environment thus created by technologies’ immense ubiquity and influence, this collaboration endeavours to recognize their full research participation, alongside that of humans. This research presents collaboratively conducted, published inquiries that have been coauthored by myself and fellow doctoral candidate Richard Wainwright. Each facilitates, then attempts to articulate ways to decentre the human in educational contexts, beginning with our own human perspectives. As exercises in broadening our considerations of the life forms, matter, and nonhuman entities that surround humanity, this research prompts us to recognize much more than what humanity typically acknowledges as existing, given the anthropocentric frameworks it has constructed. We reorientate the nature of these relationships—posthumanizing them—and in doing so, disrupt our own thinking to work something different than our circumstances have hitherto informed us to consider. We have co-developed a study and conducted research in collaboration with human and nonhuman research participants.Five nationally and internationally published co-authored journal articles, a book chapter, and five intermezzos (short “observational” pieces) comprise this study that explores collaboration and recombinatoriality during “the electric age” (McLuhan, 1969, 10:05). Recognizing humanity’s increasingly inextricable relationships with technologies, this collaboratively conducted study draws into creative assemblage Gilles Deleuze and Félix Guattari’s philosophical concepts; new materialism as cultural theory; the prescient observations and predictions of Marshall McLuhan and a media studies curriculum he co-developed over forty years ago; arts-based research; museum exhibitions; features of music production such as sampling, mashup, remix, and turntabling; among many other notes and tones. A conceptually developed riff mobilizes our inquiries as “plug in and play,” while its academic study is theorized as [onto]Riffology. Ontological shifts beget a machinic arts-based research (MABR) that develops a posthuman critical pedagogy inspired by Negri and Guattari (2010). Collaborating in the Electric Age: [onto]Riffological Experiments in Posthumanizing Education and Theorizing a Machinic Arts-Based Research celebrates collaborativity, discovery, and learning during the electric age. / Graduate / 2023-01-07 Collaborating Electric age [onto]Riffology Posthuman Posthuman education Machinic arts-based research MABR Posthuman critical pedagogy Turntabling Forcework Riff Arts-based research Riffology MashUp Mash up Vancouver Art Gallery VAG Treachery of images Marshall McLuhan City as classroom Hypercity Figure/ground analysis Thanatourism Bootstrapping Remix Collaboration The Anthropocene Project In-Review DeleuzoGuattarian concepts Poststructuralist philosophy Posthumanism Critical pedagogy Recombinatoriality Assemblage Learning event The Jimmy Dore Show Jimmy Dore Nonhuman Speculative realism Post truth era Land acknowledgements Ontologies

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