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Effect of physical activity on menopausal symptoms in non-vigorously active postmenopausal womenDuff, Shannon Marie 04 March 2008
Menopause is the time in a womans life when regular menstrual periods cease, due to a natural change in sex hormones, which may be accompanied by unwelcome symptoms. PURPOSE: To determine whether physical activity is associated with a reduction in menopausal symptoms (hot flashes, insomnia, numbness, fatigue, headaches, psychological symptoms, urogenital symptoms and physical symptoms). Providing that symptom differences among activity levels exist, a secondary purpose was to suggest an adequate level of physical activity for relief of menopausal symptoms. METHODS: Women (n=401) who were not taking hormone replacement therapy completed two questionnaires based on a 7-day recall of an average week: the Leisure-Time Exercise Questionnaire (Godin & Shephard, 1985) and the Menopausal Index (St. Germain, Peterson, Robinson, & Alekel, 2001). Women were divided into quintiles according to their physical activity scores (1=least active, 5=most active) and compared for menopausal symptoms using first a MANCOVA with covariate percent fat, as this was the only covariate that had significant group mean differences. Secondly a MANOVA with the appropriate post-hoc analysis was conducted. RESULTS: The mean (SD) age of the participants was 58.2 (6.3), the mean years postmenopausal was 6.7 (6.0), the mean percent body fat was 37.4 (5.6) %, and 16.5% had a previous hysterectomy. Univariate tests did not identify significant group differences for hysterectomy (p=0.774) or time since menopause (p=0.440); however, there were significant group differences for percent body fat (p=0). The MANCOVA was not significant between physical activity groups with percent fat as a covariate (Wilks Lamda p = 0.126). The MANOVA indicated a significant group main effect of physical activity on menopausal symptoms (Wilks Lamda p = 0.034). Of the 8 symptoms under review there were significant group differences for fatigue (p=0.05), and physical symptoms (p=0.004). The post-hoc analyses identified that two least active groups reported above average fatigue occurrence whereas the three most active groups reported below average fatigue occurrence. Group 2 had significantly more physical symptom complaints than groups 4 & 5. Of the three symptoms comprising physical symptoms, there were significant differences for weight gain (p=0.004) but not for breast tenderness (p=0.742) or aches and pains (p=0.175). Groups 1 & 2 reported significantly higher frequency of weight gain than groups 4 & 5. CONCLUSION: Any indirect effect of physical activity on menopausal symptoms is most likely through the alteration of body composition. Women with lower percent body fat report less weight gain and fatigue. There was no significant relationship between physical activity levels and reporting of hot flashes/night sweats, insomnia, limb numbness, headache, psychological symptoms or urogenital symptoms. A randomized controlled clinical trial would likely determine the relationship between higher activity levels and symptom reduction. For future research it is recommended that groups be matched based on percent body fat prior to randomization and that a greater amount of physical activity be prescribed.
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Effect of physical activity on menopausal symptoms in non-vigorously active postmenopausal womenDuff, Shannon Marie 04 March 2008 (has links)
Menopause is the time in a womans life when regular menstrual periods cease, due to a natural change in sex hormones, which may be accompanied by unwelcome symptoms. PURPOSE: To determine whether physical activity is associated with a reduction in menopausal symptoms (hot flashes, insomnia, numbness, fatigue, headaches, psychological symptoms, urogenital symptoms and physical symptoms). Providing that symptom differences among activity levels exist, a secondary purpose was to suggest an adequate level of physical activity for relief of menopausal symptoms. METHODS: Women (n=401) who were not taking hormone replacement therapy completed two questionnaires based on a 7-day recall of an average week: the Leisure-Time Exercise Questionnaire (Godin & Shephard, 1985) and the Menopausal Index (St. Germain, Peterson, Robinson, & Alekel, 2001). Women were divided into quintiles according to their physical activity scores (1=least active, 5=most active) and compared for menopausal symptoms using first a MANCOVA with covariate percent fat, as this was the only covariate that had significant group mean differences. Secondly a MANOVA with the appropriate post-hoc analysis was conducted. RESULTS: The mean (SD) age of the participants was 58.2 (6.3), the mean years postmenopausal was 6.7 (6.0), the mean percent body fat was 37.4 (5.6) %, and 16.5% had a previous hysterectomy. Univariate tests did not identify significant group differences for hysterectomy (p=0.774) or time since menopause (p=0.440); however, there were significant group differences for percent body fat (p=0). The MANCOVA was not significant between physical activity groups with percent fat as a covariate (Wilks Lamda p = 0.126). The MANOVA indicated a significant group main effect of physical activity on menopausal symptoms (Wilks Lamda p = 0.034). Of the 8 symptoms under review there were significant group differences for fatigue (p=0.05), and physical symptoms (p=0.004). The post-hoc analyses identified that two least active groups reported above average fatigue occurrence whereas the three most active groups reported below average fatigue occurrence. Group 2 had significantly more physical symptom complaints than groups 4 & 5. Of the three symptoms comprising physical symptoms, there were significant differences for weight gain (p=0.004) but not for breast tenderness (p=0.742) or aches and pains (p=0.175). Groups 1 & 2 reported significantly higher frequency of weight gain than groups 4 & 5. CONCLUSION: Any indirect effect of physical activity on menopausal symptoms is most likely through the alteration of body composition. Women with lower percent body fat report less weight gain and fatigue. There was no significant relationship between physical activity levels and reporting of hot flashes/night sweats, insomnia, limb numbness, headache, psychological symptoms or urogenital symptoms. A randomized controlled clinical trial would likely determine the relationship between higher activity levels and symptom reduction. For future research it is recommended that groups be matched based on percent body fat prior to randomization and that a greater amount of physical activity be prescribed.
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The effect of Agnus castus D3 on menopausal symptomsLazarus, Kerri Leigh 19 June 2014 (has links)
M.Tech. (Homoeopathy) / Please refer to full text to view abstract
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South African consumers' opinion of the potential health benefits of soy and soy products as hormone replacement therapy (HRT) / Anel Van Wyk de VriesVan Wyk de Vries, Anel January 2003 (has links)
There is an increasing awareness in the food industry about the role that
proper nutrition plays in maintaining health and preventing disease. Women
especially have always been interested in nutrition and its impact on their
well-being. This awareness has placed more pressure on the food industry to
provide a greater variety of nutritious and wholesome products which has led
to the development of a new field in the food industry, called functional foods.
These are food products that apart from the micro- and macronutrients that it
already provides have additional important physiologically active functions
that enhance health. These active components, called phytochemicals (from
plant sources) and zoochemicals (from animal sources) have changed the role
of diet in health. Functional foods can, by nature or design, bridge the
traditional gap between food and medicine and thereby provide consumers
with the opportunity to become involved in their own health care. One of these
functional foods that have been receiving increased attention and research is
soy. Apart from other health benefits of soy, such as cholesterol reduction and
bone strengthening, scientific evidence has shown that soy can be used as an
alternative for hormone replacement therapy (HRT). The increased interest in
the latter can be ascribed to the changed attitude of women, as well as
evidence of the side effects of conventional hormone replacement therapies.
Consumer research in the nutraceutical area is, however, still in its infancy
stage.
Objective:
The main objective of this study was thus to assess South African consumers'
opinion of the potential health benefits of soy and soy products as an
alternative for HRT. To attain this main objective, the following specific
objectives were stated:
To determine, by means of a consumer questionnaire, the percentage of
South African consumers who are aware of soy.
To determine, by means of an attitude scale, the attitudinal disposition
of South African consumers towards the potential health benefits of
soy and soy products as an alternative for HRT.
To determine South African consumers' opinions regarding the
menopausal related health benefits of soy.
To determine whether there is a relation between respondents who
Eat/drink soy and their opinion of the potential health benefits of soy.
To determine whether there is a relation between respondents who
never use soy and their opinion of the bone strengthening benefit of
soy.
To determine whether there is a relation between respondents' opinion
of the health benefits of soy and their opinions of soy as an alternative
for HRT and reliever of menopausal symptoms, respectively.
Methods:
In this study, consumers' opinion regarding the health benefits of soy was
evaluated using a questionnaire. Respondents were randomly selected from
nine metropolitan, as well as rural areas in South Africa, representing the four
main race groups, namely whites, blacks, coloureds and Indians. The total
sample size of the metropolitan and rural subjects was 3001. A sub-dataset
was created which included female respondents that have heard of soy before
and were premenopausal (35-44 years) and post-menopausal (50-59 years) of
age. Thus, the total number of respondents used for further statistical analyses
was 825. The respondents expressed their opinions of the health benefits of
soy on a five-point hedonic (Likert) scale which was adapted to a three-point
scale for easier interpretation of the tables.
Results:
1. Of the 3 001 respondents, 2 437 (80%) were aware of soy.
2. A mean attitudinal disposition score of 2.47 on a three-point scale
indicated a neutral to positive attitudinal disposition of the South
African consumer population towards the potential health benefits of
soy and soy products as alternative for HRT. No practically significant
differences were found between the mean values of each statement,
which indicated that no specifically strong opinions were expressed
between different races or between different age groups.
3. Of all the consumers surveyed and those who did express a specific
opinion, 72% agreed that soy has many health benefits compared to
only 7% who disagreed. Although 34% of South Africans expressed a
positive opinion when asked if soy can be used as alternative for HRT,
the majority (46%) of the population had a neutral opinion. Forty-two
percent of the consumers who held an opinion regarding soy as reliever
of menopausal symptoms were positive, 35% had a neutral opinion and
23% of South Africans did not agree that soy can relieve menopausal
symptoms.
4. A relation, although not of practical significance, was found between
respondents who eat/drink soy and their opinion of the health benefits
of soy. Of the respondents who indicated that they eat/drink soy, the
majority agreed that soy has many health benefits. The respondents
who disagreed when asked if they eat/drink soy, still expressed an
overall positive opinion when asked whether soy has many health
benefits.
5. A relation, although not of practical significance, was found between
respondents who never use soy and their opinion of the bone
strengthening benefit of soy. Of those who indicated that they use soy,
the majority agreed that soy has a bone strengthening benefit. On the
contrary, only 43% of those who agreed that they never use soy were
positive about the bone strengthening benefit of soy, whereas 37% held
a neutral opinion and 20% expressed a negative opinion.
6. The relation between respondents' opinion of the overall health
benefits of soy and their opinion of soy as alternative for HRT and
reliever of menopausal symptoms was of practical significance. Of the
respondents who did not agree that soy has many health benefits, the
majority expressed a negative opinion of soy as an alternative for HRT.
Of those who agreed that soy has many health benefits, 45% expressed
a neutral opinion and 44% a positive opinion of soy as alternative for
HRT. Almost half (47%) of the respondents who agreed that soy does
have many health benefits, expressed a neutral opinion when asked if
soy can relieve menopausal symptoms, whereas only 30% had a
positive opinion in this regard. The majority (86%) of the respondents
who disagreed that soy has many health benefits, also expressed a
negative opinion of soy as reliever for menopausal symptoms
Conclusion:
The results of this study indicate that 80% of the South African consumer
population are aware of soy and that South African consumers have a neutral
to positive attitudinal disposition towards the potential health benefits of soy.
Respondents did not express a particularly strong opinion regarding several
health benefits of soy. It may be hypothesized that they are not informed well
enough on the health benefits of soy as to take a stand and to form a definite
opinion. Neither different race groups, nor pre- or post-menopausal women
differ significantly in the frequency of their opinions, indicating that in this
study, race and age did not have a practical significant influence on opinion of
the health benefits of soy.
Of all those surveyed and who did express a specific opinion, 72% agreed that
soy has many health benefits, which is almost the same percentage (74%) as
American consumers who perceive soy products as healthy as according to the
United Soybean Board (USB) National Report (2003-2004:4). A survey by
Adams (2001:433) reported that 71% of American consumers believed that
plant-derived HRT have fewer risks and can thus be used as a safe alterative
for conventional HRT. According to the results of the present study only 34%
of South African consumers expressed a positive opinion when asked if soy
can be used as an alternative for HRT. Insufficient evidence on the safety and
efficacy of the potential health benefits of soy, as well as a lack of consumer
education in South Africa, could be the reason for this uncertainty among
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South African consumers. While only 26% of American consumers are aware
that soy might relieve menopausal symptoms (USB National Report, 2003-
2004:4), results of the current study found that 42% of South Africans were of
opinion that soy can relieve menopausal symptoms.
A relation, although not of practical significance, was found between
respondents who eat/drink soy and their opinion of the health benefits of soy.
This can be an indication that whether or not the South African consumer
population consume soy doesn't have an influence on their opinion of soy's
health benefits in practice. The relation found between respondents who never
use soy and their opinion of the bone strengthening benefit of soy were not of
practical significance. This can be an indication that whether or not South
Africans use soy does not influence their opinion of the bone strengthening
benefit of soy in practice. Furthermore, a practically significant relation was
found between respondents' opinion of the overall health benefits of soy and
their opinion of soy as alternative for HRT and reliever of menopausal
symptoms, respectively. Interestingly, respondents who expressed a positive
opinion regarding the health benefits of soy did not have a convincingly
positive opinion of soy as alternative for HRT and as reliever of menopausal
symptoms. They expressed a more neutral opinion. As expected, consumers
that were not of opinion that soy has certain health benefits, also disagreed
when asked if soy can be used as an alternative for HRT or as reliever of
menopausal symptoms.
Although the causes for the respondents' opinion or uncertainty were not
determined in this study, it can be hypothesised that it may be due to lack of
standardisation of evidence on the safety and efficacy of alternative hormone
replacement therapies. Further studies are still needed to determine the
contributing factors which influence consumers' opinion or lack of opinion on
soy. If consumers are not educated about the benefits and disadvantages of
soy as alternative for HRT, they cannot make intelligent decisions and
choices as to whether or not to use soy as alternative for HRT. / Thesis (M. Consumer Science)--North-West University, Potchefstroom Campus, 2004.
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South African consumers' opinion of the potential health benefits of soy and soy products as hormone replacement therapy (HRT) / Anel Van Wyk de VriesVan Wyk de Vries, Anel January 2003 (has links)
There is an increasing awareness in the food industry about the role that
proper nutrition plays in maintaining health and preventing disease. Women
especially have always been interested in nutrition and its impact on their
well-being. This awareness has placed more pressure on the food industry to
provide a greater variety of nutritious and wholesome products which has led
to the development of a new field in the food industry, called functional foods.
These are food products that apart from the micro- and macronutrients that it
already provides have additional important physiologically active functions
that enhance health. These active components, called phytochemicals (from
plant sources) and zoochemicals (from animal sources) have changed the role
of diet in health. Functional foods can, by nature or design, bridge the
traditional gap between food and medicine and thereby provide consumers
with the opportunity to become involved in their own health care. One of these
functional foods that have been receiving increased attention and research is
soy. Apart from other health benefits of soy, such as cholesterol reduction and
bone strengthening, scientific evidence has shown that soy can be used as an
alternative for hormone replacement therapy (HRT). The increased interest in
the latter can be ascribed to the changed attitude of women, as well as
evidence of the side effects of conventional hormone replacement therapies.
Consumer research in the nutraceutical area is, however, still in its infancy
stage.
Objective:
The main objective of this study was thus to assess South African consumers'
opinion of the potential health benefits of soy and soy products as an
alternative for HRT. To attain this main objective, the following specific
objectives were stated:
To determine, by means of a consumer questionnaire, the percentage of
South African consumers who are aware of soy.
To determine, by means of an attitude scale, the attitudinal disposition
of South African consumers towards the potential health benefits of
soy and soy products as an alternative for HRT.
To determine South African consumers' opinions regarding the
menopausal related health benefits of soy.
To determine whether there is a relation between respondents who
Eat/drink soy and their opinion of the potential health benefits of soy.
To determine whether there is a relation between respondents who
never use soy and their opinion of the bone strengthening benefit of
soy.
To determine whether there is a relation between respondents' opinion
of the health benefits of soy and their opinions of soy as an alternative
for HRT and reliever of menopausal symptoms, respectively.
Methods:
In this study, consumers' opinion regarding the health benefits of soy was
evaluated using a questionnaire. Respondents were randomly selected from
nine metropolitan, as well as rural areas in South Africa, representing the four
main race groups, namely whites, blacks, coloureds and Indians. The total
sample size of the metropolitan and rural subjects was 3001. A sub-dataset
was created which included female respondents that have heard of soy before
and were premenopausal (35-44 years) and post-menopausal (50-59 years) of
age. Thus, the total number of respondents used for further statistical analyses
was 825. The respondents expressed their opinions of the health benefits of
soy on a five-point hedonic (Likert) scale which was adapted to a three-point
scale for easier interpretation of the tables.
Results:
1. Of the 3 001 respondents, 2 437 (80%) were aware of soy.
2. A mean attitudinal disposition score of 2.47 on a three-point scale
indicated a neutral to positive attitudinal disposition of the South
African consumer population towards the potential health benefits of
soy and soy products as alternative for HRT. No practically significant
differences were found between the mean values of each statement,
which indicated that no specifically strong opinions were expressed
between different races or between different age groups.
3. Of all the consumers surveyed and those who did express a specific
opinion, 72% agreed that soy has many health benefits compared to
only 7% who disagreed. Although 34% of South Africans expressed a
positive opinion when asked if soy can be used as alternative for HRT,
the majority (46%) of the population had a neutral opinion. Forty-two
percent of the consumers who held an opinion regarding soy as reliever
of menopausal symptoms were positive, 35% had a neutral opinion and
23% of South Africans did not agree that soy can relieve menopausal
symptoms.
4. A relation, although not of practical significance, was found between
respondents who eat/drink soy and their opinion of the health benefits
of soy. Of the respondents who indicated that they eat/drink soy, the
majority agreed that soy has many health benefits. The respondents
who disagreed when asked if they eat/drink soy, still expressed an
overall positive opinion when asked whether soy has many health
benefits.
5. A relation, although not of practical significance, was found between
respondents who never use soy and their opinion of the bone
strengthening benefit of soy. Of those who indicated that they use soy,
the majority agreed that soy has a bone strengthening benefit. On the
contrary, only 43% of those who agreed that they never use soy were
positive about the bone strengthening benefit of soy, whereas 37% held
a neutral opinion and 20% expressed a negative opinion.
6. The relation between respondents' opinion of the overall health
benefits of soy and their opinion of soy as alternative for HRT and
reliever of menopausal symptoms was of practical significance. Of the
respondents who did not agree that soy has many health benefits, the
majority expressed a negative opinion of soy as an alternative for HRT.
Of those who agreed that soy has many health benefits, 45% expressed
a neutral opinion and 44% a positive opinion of soy as alternative for
HRT. Almost half (47%) of the respondents who agreed that soy does
have many health benefits, expressed a neutral opinion when asked if
soy can relieve menopausal symptoms, whereas only 30% had a
positive opinion in this regard. The majority (86%) of the respondents
who disagreed that soy has many health benefits, also expressed a
negative opinion of soy as reliever for menopausal symptoms
Conclusion:
The results of this study indicate that 80% of the South African consumer
population are aware of soy and that South African consumers have a neutral
to positive attitudinal disposition towards the potential health benefits of soy.
Respondents did not express a particularly strong opinion regarding several
health benefits of soy. It may be hypothesized that they are not informed well
enough on the health benefits of soy as to take a stand and to form a definite
opinion. Neither different race groups, nor pre- or post-menopausal women
differ significantly in the frequency of their opinions, indicating that in this
study, race and age did not have a practical significant influence on opinion of
the health benefits of soy.
Of all those surveyed and who did express a specific opinion, 72% agreed that
soy has many health benefits, which is almost the same percentage (74%) as
American consumers who perceive soy products as healthy as according to the
United Soybean Board (USB) National Report (2003-2004:4). A survey by
Adams (2001:433) reported that 71% of American consumers believed that
plant-derived HRT have fewer risks and can thus be used as a safe alterative
for conventional HRT. According to the results of the present study only 34%
of South African consumers expressed a positive opinion when asked if soy
can be used as an alternative for HRT. Insufficient evidence on the safety and
efficacy of the potential health benefits of soy, as well as a lack of consumer
education in South Africa, could be the reason for this uncertainty among
XIV
South African consumers. While only 26% of American consumers are aware
that soy might relieve menopausal symptoms (USB National Report, 2003-
2004:4), results of the current study found that 42% of South Africans were of
opinion that soy can relieve menopausal symptoms.
A relation, although not of practical significance, was found between
respondents who eat/drink soy and their opinion of the health benefits of soy.
This can be an indication that whether or not the South African consumer
population consume soy doesn't have an influence on their opinion of soy's
health benefits in practice. The relation found between respondents who never
use soy and their opinion of the bone strengthening benefit of soy were not of
practical significance. This can be an indication that whether or not South
Africans use soy does not influence their opinion of the bone strengthening
benefit of soy in practice. Furthermore, a practically significant relation was
found between respondents' opinion of the overall health benefits of soy and
their opinion of soy as alternative for HRT and reliever of menopausal
symptoms, respectively. Interestingly, respondents who expressed a positive
opinion regarding the health benefits of soy did not have a convincingly
positive opinion of soy as alternative for HRT and as reliever of menopausal
symptoms. They expressed a more neutral opinion. As expected, consumers
that were not of opinion that soy has certain health benefits, also disagreed
when asked if soy can be used as an alternative for HRT or as reliever of
menopausal symptoms.
Although the causes for the respondents' opinion or uncertainty were not
determined in this study, it can be hypothesised that it may be due to lack of
standardisation of evidence on the safety and efficacy of alternative hormone
replacement therapies. Further studies are still needed to determine the
contributing factors which influence consumers' opinion or lack of opinion on
soy. If consumers are not educated about the benefits and disadvantages of
soy as alternative for HRT, they cannot make intelligent decisions and
choices as to whether or not to use soy as alternative for HRT. / Thesis (M. Consumer Science)--North-West University, Potchefstroom Campus, 2004.
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Use of Hormone Therapy for Menopausal Symptoms: A Shared DecisionBlackwelder, Reid B. 01 August 2008 (has links)
No description available.
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Prophylactic, Risk-Reducing Surgery in Unaffected BRCA-Positive Women: Quality Of Life, Sexual Functioning and Psychological Well-BeingTollin, Sharon 01 January 2011 (has links)
Women with an inherited BRCA mutation are at significantly increased risk for breast and ovarian cancer, often diagnosed at an earlier age than sporadic cancers. Prophylactic surgery, with bilateral mastectomy and/or bilateral prophylactic salpingo-oophorectomy, represents an option for risk reduction. The purpose of this study was to explore quality of life, sexual functioning, menopausal symptoms, psychological well-being and satisfaction with risk management decisions for BRCA-positive women ages 21 to 50 (M = 38.4 years), without a personal history of cancer. A web-based, cross-sectional study design was utilized to compare women opting for any prophylactic surgery (n = 160) with those without a history of prophylactic surgery (n = 71). Quality of life (per the Quality of Life Index, Self-Anchoring Striving Scale and Body Image Quality of Life measures) and Psychological General Well-Being Index scores were essentially the same across the entire study sample. While controlling for age, prophylactic surgery (PS) predicted more severe symptoms of sexual dysfunction as measured by the Female Sexual Functioning Index (total score, Desire, Arousal, Lubrication and Satisfaction domains). Similarly, PS predicted menopausal symptoms and sleep difficulties. Women who had not undergone any prophylactic surgery had higher levels of Stigma and lower levels of Mastery, as measured by the BRCA Self-Concept scale. Prophylactic surgery also predicted higher levels of Satisfaction with Decision for hereditary cancer risk management. Findings from this exploratory study provide insight into the quality of life, sexual functioning and psychological well-being for unaffected, BRCA-positive women. Additional research is needed to examine sexual functioning prospectively, to further investigate the potential sequelae of risk-reducing surgery.
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Hot Flashes in Relation to Breast Cancer Endocrine TherapyVan Der Wall, Ana 01 January 2015 (has links)
Women undergoing endocrine therapy for breast cancer often experience hot flashes. As part of a performance improvement project, 14 patients were surveyed to determine who is at risk for hot flashes during endocrine therapy. This information encourages the education of patients, increases compliance with therapy, and improves quality of life.
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Age at natural menopause and menopausal symptoms among Saudi Arabian women in Al-KhobarAl-Sejari, Maha M. 13 July 2005 (has links)
No description available.
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Fluoreszenzmikroskopische Untersuchung der Wirkung von Östrogen, Alendronat, Raloxifen und Cimicifuga auf die Knochenheilung der ovarektomierten Ratte / Fluorescence mikroscopical analyze of the effekt of Estrogen, Alendronat, Raloxifen and black cohosh on fractue healing in ovariectomized ratsWenda, Eliane 22 February 2011 (has links)
No description available.
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