This thesis is about moods in works of art, and how moods expressed in art can change how we view the world. Among those who speak of the value of discussing moods in philosophical aesthetics, it is normally assumed that the value of moods is in the way they are induced in the viewer of the work. In this thesis, I will argue that such an argument is not the best. Those who think moods are not relevant to aesthetics have only to argue either that being induced with emotions is not an ideal way of approaching art, or that such reactions as being induced with mood belong to the more rare cases of approaching art. Therefore, focusing on how moods are induced hinders the potential of discussing moods in art. Instead I argue that the value of moods is in the way they are expressed. I argue that moods can be understood as a form of symbolic schemas. They affect how the world appears, and how one sorts and organizes things in the world. One can therefore use moods as resources for getting knowledge about the world. Because some works of art express moods, where expression is understood as metaphorical exemplification, they make the viewer epistemically aware of the mood. Thus one can imagine being in the mood expressed. Thereby moods can lead to knowledge, also in cases where they are not literally induced. When one succesfully imagines being in an expressed mood, parts of the world are sorted and organized differently as in accordance with the mood.

<p>The relationship between positive urgency, a personality trait reflecting rash action during extreme positive emotional states, and risk-taking has previously been experimentally examined. However, how positive urgency is related to risk-taking while under the acute influence of alcohol has not been examined. The overarching goal of this dissertation was to generate behavioral evidence concerning how the interaction between positive urgency and alcohol consumption influences risk-taking via changes in emotional arousal. In this study, 59 community-dwelling adults (mean age = 29.45 (SD = 10.96), 32.2% women, 78% White) completed mood induction procedures (positive or neutral) while consuming a beverage (alcohol or placebo) and then completed the Balloon Analogue Risk Task (BART) as a measure of risk-taking. The positive mood induction was effective in inducing high arousal positive emotions. Overall, study hypotheses were not supported; however, because of low power, effect sizes and patterns of relationship are reported. The relationship between positive urgency and risk-taking was positive and small in the positive mood condition but negative and small in the neutral mood condition. The alcohol group and the placebo group showed similar patterns of risk-taking that are positive and small. Finally, the relationship between positive urgency changes in emotional arousal was positive and small only in the positive/alcohol condition; however, there was no relationship between changes in emotional arousal and risk-taking. These findings suggest that, while changes in emotional arousal may result from a combination of positive urgency and alcohol consumption, it may not be a focal mechanism that explains the relationship between positive urgency and risk-taking. Further, positive urgency is a risk factor whether or not alcohol consumption is present. Although the small sample size limited the power to test the hypotheses, the effect size estimates obtained in this study provide preliminary data for a more properly powered future study. The pattern of findings suggests the viability of further developing the current positive mood induction to establish a lab-based paradigm for positive urgency and the use of a different experimental risk-taking task to examine positive emotion-based risk-taking.</p>

Introduction: Cardiovascular disorders contribute significantly to mortality and morbidity amongst patient's psychotic disorders such as schizophrenia and bipolar mood disorders. In addition to conventional risk factors for cardiovascular disorders (smoking, alcohol use, inadequate physical activity, hypertension, diabetes, dyslipidaemia, obesity and metabolic syndrome, and non-modifiable factors such as sex, age and social-economic status) exposure to potentially traumatic events, psychological distress, comorbidity of other medical conditions, and use of antipsychotics may also increase cardiovascular risk in patients with psychosis. There is also evidence to suggest that intervention to mitigate such cardiovascular risk factors are suboptimal, hence contributing to poor outcomes. Despite growing interest in cardiovascular health, there remains a paucity of data on the prevalence of the various cardiovascular risk factors among patients with psychosis in low resource settings such as Sub-Saharan Africa. This is likely to differ from high resource contexts given social-cultural and economic differences as well as differences in the health systems. In order to design contextually relevant cardiovascular risk screening, treatment and prevention guidelines that can be integrated into routine care of the mentally ill patients in low- and middle-income countries (LMICs), further work in this setting is warranted. Objectives: The aim of this thesis was to establish the cardiovascular risk profile among patients treated for psychotic disorders at Moi Teaching and Referral Hospital (MTRH) in Eldoret, Western Kenya. Specific objectives were as follows: 1. To conduct a literature review on the burden and etiological mechanisms of cardiovascular risk in patients with psychosis, with a focus on LMIC. 2. To compare the prevalence, as well as sociodemographic and clinical correlates, of conventional cardiovascular risk factors (smoking, alcohol intake, poor diet, and lack of exercise, diabetes mellitus, hypertension, obesity, dyslipidaemia and metabolic syndrome) in patients with psychosis versus matched controls. 3. To establish the prevalence and correlates of non-conventional risk factors; psychological distress, traumatic events (lifetime and childhood trauma) and comorbid medical disorders in patients with psychosis and controls, and to delineate how these risk factors contribute to the overall cardiovascular risk. 4. To describe current psychopharmacological treatments and explore potential associations with cardiovascular risk among patients with psychosis. 5. To explore the overall 10-year cardiovascular disease risk, as well as the social demographic and clinical correlates among patients and controls. 6 .To determine the proportion of untreated metabolic disorders (hypertension, diabetes mellitus, and dyslipidaemia) in patients with psychotic disorders and matched controls. Methods: This was a cross-sectional descriptive survey comparing 300 patients with psychosis and 300 controls at Moi Teaching and Referral Hospital, Western Kenya. A paper based researcher-administered questionnaire was used to collect data on demographic variables (age, sex, education level, and marital status), and risk factors (smoking, alcohol intake, diet, physical activity). We used the Composite International Diagnostic Interview (CIDI) to assess for presence of other chronic medical disorders. Data on childhood trauma were obtained using the Childhood Trauma Questionnaire (CTQ) while the Life Events Checklist (LEC) was used to obtain data on lifetime exposure to potentially traumatic events. Data on psychological distress among controls were obtained using the Kessler-10 questionnaire. Measurements of weight, height, abdominal circumference and blood pressure were taken from each of the participants. Blood was drawn for measurement of glucose level and lipid profile. Data analysis was undertaken using Stata version 15. T-tests were used to compare continuous variables while Pearson chi-squared tests was used for categorical variables. Regression modelling was undertaken to assess associations between sociodemographic and clinical predictor variables and the cardiovascular risk factors. Results: Data collection took place between July 2018 and March 2019. The mean age of patients was 33 years and of controls was 35 years. Compared to controls, patients were more likely to be unmarried (46% vs 33% p< 0.001), and were reduced among females (OR 0.41 p20). The estimated 10 year cardiovascular risk was significantly associated with female Sex (p=0.007), age (p <0.001), current tobacco smoking (p <0.001) and metabolic syndrome (P<0.001). Among the patients, 280 (94.3%) patients were on antipsychotics with the majority (86.5%) being treated with olanzapine. Of all the participants with diabetes 60% among patients and 22% among controls were not on treatment. Of the total number of participants with hypertension, 65% of patients and 47% controls were not on treatment. Conclusion: In the study setting of Eldoret, Western Kenya, patients with psychosis were found to have high levels of lifestyle cardiovascular risk factors such as smoking, inadequate intake of fruits and vegetables and inadequate physical activity. They were also found to have high rates of metabolic disorders such as hypertension, obesity, metabolic syndrome and dyslipidaemia. There was no evidence of increased cardiovascular risk among participants exposed to traumatic life events, with those experiencing psychological distress or those with other chronic medical disorders. The use of olanzapine was not significantly associated with increased cardiovascular risk in this setting. There was an identifiable gap in the treatment of cardiovascular risk factors in this setting. Given these findings, we recommend efforts to address these risk factors by development of protocols to ensure screening for these risk factors, adequate documentation and appropriate treatment.

In the context of video games, a portrayed mood can bring forward emotion and make a scene more alive. With the use of dynamic mood, the look and feel of the game may change provided dynamic events, as dictated by player inputs and various sets of conditions. This thesis aims to describe and present a range of techniques that are subject of affecting the in-game mood, as implemented into an original development project. By using select design patterns, carefully authored parameters and intuitive areas of implementation, the mood and atmosphere of the game experience can be altered dynamically in meaningful ways. / Ur ett datorspelsperpektiv så kan en viss stämning väcka känslor och få en miljö att kännas mer levande. Med dynamisk stämning så menas att spelets utseende och känsla kan förändras med hjälp av dynamiska händelser, formade efter indata från spelaren och olika uppsättningar av villkor. Detta dokument har för avsikt att presentera en rad tekniker som kan användas för att påverka ett spels stämning på ett dynamiskt och betydelsefullt sätt. Genom att välja rätt designmönster, noggrant formulera parametrar samt utforska intuitiva utvecklingsområden så demonstreras detta inför ett verkligt spelprojekt.

Objectives: To examine the association between depressed mood and clusters of health risk behaviors. Methods: A nationally representative sample of adolescents (N=15,214) was utilized to construct 10 pseudocontinuous health risk behaviors. Cluster analysis was performed to group adolescents, and subsequent multivariable logistic models were created. Results: Compared to non-risk takers, belonging to risk clusters significantly increased the odds of reporting depressed mood. African Americans in high-risk clusters appeared to be more vulnerable to depressed mood, when compared to remaining racial groups. Conclusions: Results suggest that adolescents engaging in multiple health-risk behaviors do so in the context of depressed mood.

The classic nonparametric confidence intervals for a difference or ratio of medians assume that the distributions of the response variable or the log-transformed response variable have identical shapes in each population. Asymptotic distribution-free confidence intervals for a difference and ratio of medians are proposed which do not require identically shaped distributions. The new asymptotic methods are easy to compute and simulation results show that they perform well in small samples.

This study examined which particular facets of mindfulness (nonreactivity, observing thoughts and feelings, acting with awareness, describing experience, and nonjudging of experience) accounted for improvements in mood and warning signs of relapse in an adult population. This exploratory study examined the impact of the five facets of mindfulness on both warning signs of relapse and mood in a primarily minority adult population in a residential substance abuse treatment facility. Results showed that all five facets were significantly correlated with mood and warning signs at the bivariate level. When considering the facets together, observing and nonjudging were related to mood, and acting with awareness and nonjudging were related to warning signs. Implications for future research and practice are offered.

Ms. K is a 19-year-old Caucasian female with no prior psychiatric diagnoses who presented to outpatient clinic with chief complaint of depressed mood. She reports depressed mood, low energy, low motivation, low self-esteem, anhedonia, and loss of appetite for past 2 months. She reports sleeping only 4 hours per night and denies daytime naps. She was diagnosed with major depressive disorder according to Diagnostic and Statistical Manual of Mental Disorder, 5 edition in our outpatient clinic. She denies suicidal thought, homicidal thoughts, or plan. She denies hopelessness, worthlessness, and recurrent thoughts of death. She denies history of mania, psychosis, PTSD, eating disorder or OCD. She works as a server at a local restaurant. She denies tobacco, alcohol use and other illicit substance use. She doesn’t have history of inpatient hospitalization, suicide attempt or homicide attempt. She had not tried psychotropics in the past. She doesn’t have any medical illness and not on any current medications. She has history of nocturnal enuresis at age 6 improved and remitted with minimizing fluid intake before bedtime and enuresis alarm. She was started on fluoxetine 10mg daily for 7 days and increase to 20mg daily for depression. She came for follow up 4 weeks later. She reported significant improvement in her mood, energy, interest, and sleep. She has been sleeping 8 hours per night. During the follow up she denied depressed and other depressive symptoms. She reported onset of nocturnal enuresis 1 weeks after start of fluoxetine. She is reporting nocturnal enuresis 4 times a week. fluoxetine 20mg daily was decreased to 10mg daily however enuresis persisted. After discussing with patient, we decided to discontinue fluoxetine and start escitalopram 10mg daily for depression. 4 days later, patient reported that nocturnal enuresis resolved completely. Patient reached remission of her depressive symptoms on escitalopram 10mg daily. Case reports describing SSRI induced incontinence with paroxetine, sertraline have been published. Escitalopram is extremely selective for serotonergic transport proteins when compared with other antidepressant such as sertraline, fluoxetine, paroxetine, and fluvoxamine. Clinicians should keep in mind the possibility that enuresis may possible be either precipitated or exacerbated by SSRI. In this poster, we discuss fluoxetine induced enuresis, possible mechanism and bladder pathophysiology.

Background: It is known that both severe mental illness and violence have genetic components. Multiple genes play a role in the cause of violent behaviour. Violence is one of the leading causes of death for young people in South Africa and yet little is known about its prevalence in state patients and their family members. Aim: This study aimed to investigate the prevalence of violence and mental illness in the families of state patients, to what extend these coincide and to compare schizophrenia and mood psychosis in that context. Setting: The study included 60 state patients' folders, all of whom were diagnosed with a psychotic disorder, in accordance with DSM5 criteria. The subjects were divided into two groups: those who have committed violence and those who have not committed violence. Method: Patients' folders were selected by purposive sampling. These folders were then reviewed by the researcher and a questionnaire was completed. Results: Violent patients had more first-generation relatives with violent convictions (68.2%), compared to 36.4% of non-violent patients. Only 3.3% of non-violent patients witnessed domestic violence, whereas 13.3% of violent patients witnessed domestic violence. A significantly higher proportion of patients with bipolar disorder had been convicted of physical assault (p=0.035). 17.6% of violent schizophrenia patients had a family history of violence and mental illness, compared to 18.2% of violent patients with mood psychoses which is not statistically significant. Conclusion: It was found that violence runs in families and that mental illness and violence was prevalent in the described group. Of further concern was that more violent patients witnessed domestic violence compared to non-violent patients, emphasising the idea that the cause of violence is multifactorial (genetic, environmental), and that identification of not only high-risk patients but also high-risk families need to be implemented.

The present study was designed to test the causal locus hypothesis, and to develop and explore the selfevaluational hypothesis. The causal locus hypothesis is based on attribution, which is a person's perception of cause. The hypothesis holds that persons making internal attributions (self-caused) for failure end external attributions (not self-caused) for success experience more negative postoutcome mood than persons making external attributions for failure and internal attributions for success. The hypothesis was derived from major theories or attribution, but was not experimentally tested until recently (Wollert et al., 1981).