Presentation given on October 27, 2016 at Data Reproducibility: Integrity and Transparency program as part of Open Access Week 2016. / The NIH is now requiring the authentication of Key Biological Resources to be specified in a scored portion of most grant applications, but what does it mean to authenticate? We will discuss what Key Biological Resources are, the ongoing efforts to understand how to authenticate them and of course the resources available, including examples. The journal response to authentication will also be pointed to and practical steps that every researcher can take today to improve reporting of research in scientific publication.

The present study attempted to investigate the information needs/information seeking behaviour of health researchers at the National Institute of Health Research and Development, Ministry of Health, Indonesia. Its objective was to identify the relationship between information needs/information seeking behaviour and the characteristics of those health professionals. Those characteristics include institution to which health professionals belonged, institution geographic location, level of appointment, level of education, and work experience. Research was carried out through survey by using a questionnaire. This survey obtained a response rate of 92 percent from a sample of 131 health professionals. Their information needs/information seeking behaviour were correlated with their characteristics to determine relationships, and the Statistical Package for the Social Sciences (SPSS) was used to analyse the data. Frequency distribution, chi-square analysis, and descriptive analysis were used to obtain the results. The study found that the health information available did not match the health professionals' needs and that there was strong demand by these personnel for automated information services. It also found that total hours reading per week was significantly related to level of appointment, level of education, and work experience at other institutions. The perceived usefulness of journals as information sources was significantly related to institution, geographic location, level of appointment, level of education and work experience at other institutions. Government publications and statistical data as a source of information were found to be related significantly to institution and geographic location. There was also a relationship between the perceived value of reference books and work experience at the current institution. The usefulness of library catalogues as a guide to information was found to be related significantly to institution and geographic location, as was the usefulness of abstracting and indexing services to level of education. Frequency of visiting libraries was significantly related to institution, geographic location and level of appointment. The membership of professional organizations and obtaining useful information from friends, colleagues or personal contact were found to be significantly related to level of education. The study concludes with recommendations and suggestions for further research.

El Instituto Nacional de Salud ente encargado del desarrollo y difusión de la investigación científica–tecnológica y a la prestación de servicios de salud en los campos de la salud pública. Es una institución líder en vigilancia que monitorea aquellas enfermedades sujetas a vigilancia y cuyos procesos se deben mantener óptimos para gestionar grandes volúmenes de información en corto tiempo y lograr indicadores que contribuyan a la toma de decisiones en el sector salud. Ante esto nuestro trabajo de investigación propone una Arquitectura Empresarial para optimizar el proceso de vigilancia en salud del Instituto Nacional de Salud, el alcance de la propuesta es proponer el modelo de arquitectura empresarial para el proceso de Vigilancia en Salud del Instituto Nacional de Salud. Este modelo base, podrá implementar los procesos operativos e integrar los componentes actuales de TI, haciendo uso óptimo de los recursos humanos y reduciendo costos. Cabe resaltar que la información utilizada para construir el presente documento fue obtenida del Portal Web del INS, de Boletines Institucionales, páginas Web y documentos de investigación publicados en internet. / The National Institute of Health, entity in charge of the development and dissemination of scientific-technological research and the provision of health services in the fields of public health. It is a leading institution in epidemiological surveillance that monitors those diseases subject to surveillance and whose processes must be kept optimal to manage large volumes of information in a short time and achieve indicators that contribute to decision-making in the health sector. Given this, our thesis proposes a Business Architecture to optimize the health surveillance process of the National Institute of Health, the scope of the proposal is to propose the business architecture model for the Health Surveillance process of the National Institute of Health. This base model will be able to implement operational processes and integrate current IT components, making optimal use of human resources and reducing costs. It should be noted that the information used to build this document was obtained from the INS Web Portal, Institutional Bulletins, Web pages and research documents published on the Internet. / Trabajo de investigación

Philosophiae Doctor - PhD / Injuries, and head injuries in particular, are a common cause of childhood, adolescent and young adulthood morbidity and mortality. The risk factors for injuries in general have been well researched. But it remains uncertain whether these factors are similar for specific injuries, such as head injuries. The inter-relationships between individual and environmental risk factors are difficult to study. Whilst much is know of the short-term consequences of head injuries, relatively little information is available on their long-term conseque~ces. The follow-up period in most research is short (often less than 1 year) and studies are weak in terms of design. Studies generally find a variety of social, cognitive and psychological consequences in children and young adults experiencing head injuries. This study assessed in two large, nationally representative samples, a 1946 birth cohort and a 1997 cross-sectional health survey: 1) the occurrence and risk factors for childhood, adolescent and early adulthood head and other injuries, and 2) the long-term cognitive and psychiatric effects of skull injuries. The overall findings for the risk factors across the two data sets and over 5 decades of data collection were strikingly similar. Maleness was a major risk factor for the head and other injuries. Some of the behaviour and personality factors such as hyperactivity and being neurotic, even after adjusting for sex, socioeconomic status and family type, remained significantly related to injuries, particularly those affecting the head region. A clustering of demographic, socioeconomic, family and behavioural risk factors significantly increased the likelihood of injuries, particularly recurring injuries with at least one being a head injury. In the unadjusted analyses socioeconomic status and family type were less consistently related to injuries. The long-term psychiatric and cognitive consequences of skull injuries causing concussion and skull fractures in childhood and early adulthood were negligible. Other childhood factors such as educational ability, behaviour and personality, and level of education achieved were more predictive of psychiatric symptoms and cognitive problems in adulthood. This study suggests that children and adolescents with behavioural and personality problems were at greater risk of head and other injuries in childhood, adolescence and later in adulthood. Children and adolescents with behavioural and personality problems were more likely to live in manual social class families and families with a single parent or stepparent. This combination of behavioural problems and deprived socioeconomic and family circumstances may increase tendencies for violent behaviour, alcohol dependence and manual occupations later in adulthood, which all increase the risk of injuries. There is therefore a need to identify children and adolescents with behavioural and personality problems as early as possible to prevent the impact in the short- and longterm. This will not only reduce the burden of injuries but also the many other consequence of behavioural and personality problems, particularly when located within deprived socioeconomic and family circumstances.