Thesis--Wisconsin. / Vita. Includes bibliographical references (leaves 142-144).

Thesis (Ph. D.)--The University of Wisconsin--Madison, 1972. / Typescript. Vita. eContent provider-neutral record in process. Description based on print version record. Includes bibliography.

München, Techn. Univ., Diss., 2000.

This thesis investigates bullying and negative behaviour among chefs working in commercial kitchens. The idea for this study arose due to evidence from the hospitality industry and amongst chefs in particular which suggested that negative behaviour and bullying were widely accepted practices. However, much of this evidence has been either anecdotal from media reporting or based on small scale studies.The industry has also complained about high labour turnover and the need for a trained workforce. Therefore, this study examines the behaviours to which chefs are exposed and if negative behaviours cause them to leave the industry.This thesis has used a questionnaire to measure responses from chefs who were either in training in catering colleges or working in the industry. Questionnaires were distributed to first year student chefs (n = 202), final year student chefs (n = 153) and working chefs (n = 304). Working chefs and final year student chefs were given questionnaires that included a behavioural method of measuring bullying, known as the NAQ-R, a self labelling method of measuring bullying and items about kitchen specific behaviours. Working chefs and final year student chefs were also asked about positive aspects of work and job satisfaction. First year student chefs were also given a personality instrument as well as being asked their opinions of kitchen specific behaviours.The findings suggest chefs’ exposure to regular bullying was in line with another major UK study (Hoel, 2002). However, occasional bullying was much higher. An examination of industry specific behaviours revealed that chefs tolerate a range of behaviours from verbal abuse on the one hand to physical and sexual abuse on the other. There were also positive aspects about the freedom of work and job satisfaction but this study was unable to find any evidence as to what made chefs stay in the industry.The study found that as student chefs become socialised into their role they were more likely to tolerate negative work behaviours and could identify reasons for their use although, this did not mean that they necessarily agreed with them. In fact, as the working chef sample was very different in ethnicity, gender and nationality from the student sample it could mean that due to negative behaviours on graduation students may not work as chefs.

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Robert Agnew’s (1992) General Strain Theory significantly revitalized traditional scholarship in the anomie/strain tradition by offering a general theory of crime; purported to account for both criminal and analogous behaviors. GST specifically extends anomie/strain theory by introducing new sources of strain (i.e. loss of positively valued stimuli, presentation of noxious stimuli) into the theoretical framework, as well as elucidating the causal pathways (including mediating and moderating effects) leading from the experience of strain to deviant coping mechanisms. An emerging trend within GST is the identification of previously untapped sources of strain (e.g. victimization, discrimination) that ostensibly have deviancegenerating properties. Concerning the latter trend, recent empirical iterations of GST have also introduced internal (e.g. self-esteem) and external conditioning factors (e.g. social control) that have been found to exert a mediating effect on the relationship between strain-generated negative emotions and deviant coping responses. Jang and Johnson-in a recent series of studies (2003, 2005)-offered a crucial extension to the General Strain Theory (GST) literature by finding that religiosity at least partially moderates the deviance-generating effects of strain-induced negative affect among a sample of African Americans. The current study offers a key extension to the Jang and Johnson thesis by offering the most comprehensive examination of the central tenets of their research to a nationally-representative, longitudinal sample of adolescents. Results from Waves I and II of the National Longitudinal Study of Adolescent Health reveal support for GST in general, and qualified support for the Jang/Johnson thesis in particular. Strain was found to be a significant, positive predictor of depression and anger. With regard to the fundamental hypothesis of the current research, partial support was garnered for the Jang and Johnson hypothesis. In particular, religiosity only offered direct protective effects when predicting drug use, and failed to condition the relationship of strain on deviance across any of the deviance measures. Consequently, religiosity failed to moderate the effects of strain on deviant coping strategies among the full sample, although significant conditioning effects were observed for female deviance. Consequently, these results largely attribute the Jang and Johnson findings to elevated levels of religiosity in their sample.

Celebrity endorsements are a widely used marketing strategy, through which a popular celebrity is paired with the brand in order to enhance brand meaning in the eyes of consumers. However, endorsement strategies are not without risk, as evidenced by popular media revealing celebrities’ negative behavior. While much research has addressed factors enhancing endorsement effectiveness, limited research exists that examines the effects of negative celebrity information on consumer responses to the endorser and brand. The current research seeks to understand the potential differentiating effects of failure type (functional vs. nonfunctional) on related consumer attitudes and intentions. Three experiments (between subjects factorial design) were conducted to examine the phenomenon of interest. Contrary to expectations, results of the first two experiments suggest an absence of significant differentiating effects of failure type, overall, although various exceptions surfaced. These experiments represent a unique research attempt to disentangle the effects of functional and nonfunctional information on consumer responses to endorsement strategies. In addition, it contributes to the growing research interest in understanding the important effects of negative information on consumer attitudes and intentions.

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Recent studies indicate a correlation between high expression of the POZ-ZF transcription factor Kaiso, and the aggressiveness of the triple negative breast cancer (TNBC) subtype. However, little is known about the biological roles of Kaiso in TNBC tumorigenesis and metastasis, which laid the foundation for this thesis. To elucidate Kaiso’s role in TNBC, we generated stable Kaiso depletion in two well-established TNBC cell lines – MDA-MB-231 and Hs578T – using RNA interference technology. Intriguingly, we observed that Kaiso depletion delayed the tumor onset of MDA-MB-231 but not Hs578T cells, and led to the reduced expression of the c-Myc oncoprotein in MDA-MB-231 but not Hs578T cells. We postulate that this reduction in c-Myc expression is partly responsible for the delayed tumor onset observed in MDA-MB-231 cells. Additionally, loss of Kaiso expression resulted in increased apoptosis of both MDA-MB-231 and Hs578T cells in vitro and in vivo, which was accompanied by reduced expression of the DNA repair protein BRCA1. Remarkably, bioinformatic analysis revealed that high Kaiso and BRCA1 mRNA expression correlates with the reduced survival rates of TNBC patients. Further characterization of the Kaiso-depleted cells revealed that loss of Kaiso expression strongly inhibited the metastatic abilities of MDA-MB-231 and Hs578T cells. Importantly, Kaiso depletion led to decreased TGFβ-receptor I and II (TGFβRI and II) expression that is essential for the activation of the TGFβ signaling cascade. Concomitantly, suppressing Kaiso led to reduced TGFβ signaling. As increased TGFβRI expression is independently associated with the poor prognostic outcome of breast tumors, and the TGFβ signaling pathway is highly involved in breast tumor metastasis, we hypothesize that Kaiso functions together with TGFβRI and the TGFβ signaling cascade to promote TNBC metastasis. An additional goal of this thesis was to investigate the role of Kaiso in the prevalence of TNBC in women of African ancestry (WAA) compared to Caucasian women – since increased Kaiso expression is implicated in the poor survival outcomes of breast cancer patients of African ancestry relative to their Caucasian counterparts. Using tissue microarray and immunohistochemical analyses, we revealed for the first time a high nuclear expression of Kaiso in TNBC tissues of WAA (Nigerian, Barbadian, African American) compared to TNBC tissues of Caucasian women. Collectively, these findings unveiled functional oncogenic roles for Kaiso in the tumorigenesis and metastasis of TNBC, and revealed a plausible link between high Kaiso expression, high African ancestry and the predisposition of young WAA to TNBC. / Thesis / Doctor of Philosophy (PhD)