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Incremental and decremental L- and M-cone driven ERG responses: I. Square-wave pulse stimulation.McKeefry, Declan J., Kremers, Jan, Kommanapalli, Deepika, Challa, Naveen K., Murray, I.J., Maguire, John, Parry, Neil R.A. 04 1900 (has links)
No / Electroretinograms (ERGs) elicited by transient, square-wave L- and M-cone isolating stimuli were recorded from human trichromatic (n=19) and dichromatic (n=4) observers. The stimuli were generated on a 4 primary LED stimulator and were equated in terms of cone modulation (cone contrast = 0.11) and retinal illuminance (12,000 trolands). L- and M-cone isolated ERGs had waveforms similar to those observed for luminance responses. However, M-cone ERGs exhibited a phase reversal in their responses to onset and offset stimuli relative to the L-cone responses. This on-off response reversal was observed in trichromats but not dichromats. Simultaneous counter-phase and in-phase combinations of L- and M-cone isolating stimuli generated responses that reflected chromatic and luminance processing, respectively. We conclude that L- and M-cone specific ERGs provide a measure of how photoreceptors contribute to post-receptoral mechanisms.
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Compensation of Cotton to Square Removal at Various RatesPitman, Virginia Leigh 22 October 2002 (has links)
Fruit abscission is a natural occurrence in cotton. Fruiting retention is very important since yields are highly correlated with number of bolls produced. There are many factors contributing to the abscission of squares by cotton, including environmental conditions, heavy boll load, diseases, and insect feeding. An experiment was designed to evaluate the compensation capacity of cotton at various levels of square removal using two cotton cultivars at two planting dates over two Virginia locations; the effect of mechanical square removal on cotton yield components and quality; and to evaluate the use and effectiveness of COTMAN in tracking major phenological stages PHS, FF, and Cutout of cotton at various rates of square removal. In 1998, DPL 51 was planted on May first at the Tidewater Agricultural Research and Extension Center in Suffolk, Virginia. This was an ideal location, planting date, and variety, so in 1999, the experiment was expanded to ascertain whether cotton would have the same compensation capacity in less ideal conditions. In 1999, two varieties were planted, DPL 51 (early maturing) and DPL 5111 (late maturing), on two planting dates (two weeks apart), and in a location outside the traditional cotton growing region, the Southern Piedmont AREC in Blackstone, Virginia. Five levels of manual desquaring treatments (0%, 12-15%, 20-25%, and 30-40% of first position squares, and 20% of small bolls [Suffolk, 1999 only]) were used in both years. The physiological progress of the crop was monitored using the COTMAN cotton monitoring system and compared to the Target Development Curve (TDC). Over both years, there were no significant differences in boll numbers or yield among any of the square removal treatments. Comparison of fruiting curves with the TDC showed that in both 1998 and 1999, the influence of square removal in excess of 30-40% resulted in a lower apogee and premature cut-out. Also, though not statistically significant, yield was greatly reduced at the 30-40% square removal rate, often by as much as 448 kg/ha. In many cases, a lower level of square removal (varying between the 12-15% and the 20-25% rates) seemed to stimulate the growth and development of the crop. It may also contribute to a higher level of square retention. The results of this study suggest that cotton plants will compensate for up to 30% of first position square loss, with no reduction in yields. / Master of Science
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Effective Field Theory Based on the Quantum Inverted Harmonic Oscillator and the Inverse Square Potential with Applications to Schwinger Pair CreationSundaram, Sriram January 2024 (has links)
In this thesis we focus on two elementary unstable quantum systems, the inverted
harmonic oscillator and the inverse square potential, using the methods of effective
field theory (EFT) and the renormalization group (RG). We demonstrate that the
phenomenon of fall to the centre associated with the inverse square potential is an
example of a PT symmetry breaking transition. We also demonstrate a mapping
between the inverted harmonic oscillator and the inverse square potential including a
one-to-one mapping between the quantum states and boundary conditions using an
EFT framework in a renormalization group invariant way. We apply these methods
to the phenomenon of Schwinger pair production and study finite size effects using
the RG scheme for the quantum inverted harmonic oscillator. / Thesis / Doctor of Philosophy (PhD)
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Energy Absorption of Metal-FRP Hybrid Square TubesKalhor, Roozbeh 07 February 2017 (has links)
Lower-cost manufacturing methods have increased the anticipation for economical mass production of vehicles manufactured from composite materials. One of the potential applications of composite materials in vehicles is in energy-absorbing components such as hollow shells and struts (these components may be in the form of circular cylindrical shells, square and rectangular tubes, conical shells, and frusta). However, constructions which result in brittle fracture of the composite tubes in the form of circumferential or longitudinal corner crack propagation may lead to unstable collapse failure mode and concomitant very low energy absorption. As a result, metal-composite hollow tubes have been developed that combine the benefits of stable ductile collapse of the metal (which can absorb crushing energy in a controlled manner) and the high strength-to-weight ratio of the composites. The relative and absolute thicknesses of metal or FRP section has a substantial effect on energy absorption of the hybrid tubes. In particular, likelihood of delamination occurrence raises with increase in FRP thickness. This can reduce the energy absorption capability of the metal-FRP hybrid tubes. Additionally, adding a very thick FRP section may result in a global buckling failure mode (rather than local folding). Until now, there are no studies specifically addressing the effect of FRP thickness on energy absorption of hybrid tubes. In this study, the effects of fiber orientation and FRP thickness (the number of layers) on the energy absorption of S2-glass/epoxy-304 stainless steel square tubes were experimentally investigated. In addition, a new geometrical trigger was demonstrated which has positive effects on the collapse modes, delamination in the FRP, and the crush load efficiency of the hybrid tube.
To complete this study, a new methodology including the combination of experimental results, numerical modeling, and a multi-objective optimization process was introduced to obtain the best combination of design variables for hybrid metal-composite tubes for crashworthiness applications. The experimental results for the S2 glass/epoxy-304 stainless steel square tubes with different configurations tested under quasi-static compression loading were used to validate numerical models implemented in LS-DYNA software. The models were able to capture progressive failure mechanisms of the hybrid tubes. In addition, the effects of the design variables on the energy absorption and failure modes of the hybrid tubes were explained. Subsequently, the results from the numerical models were used to obtain optimum crashworthiness functions. The load efficiency factor (the ratio of mean crushing load to maximum load) and ratio between the difference of mean crushing load of hybrid and metal tube and thickness of the FRP section were introduced as objective functions. To connect the variables and the functions, back-propagation artificial neural networks (ANN) were used. The Non-dominated Sorting Genetic Algorithm–II (NSGAII) was applied to the constructed ANNs to obtain optimal results. The results were presented in the form of Pareto frontiers to help designers choose optimized configurations based on their manufacturing limitations. Such restrictions may include, but are not limited to, cost (related to the number of layers), laminate architecture (fiber orientation and stacking sequence) which can be constrained by the manufacturing techniques (i.e. filament winding) and thickness (as an example of physical constraints). / Ph. D. / In a car accident, the incident energy must be absorbed by elements of the vehicles to prevent it from being transferred to the occupants. (Indeed, a vehicle that is not damaged in a crash may lead to significant injury to occupants.) Typical energy absorbing elements in a vehicle include hollow shells and struts in the crumple zone, bumpers, and airbags. The focus of this study is on hollow thin-walled tubes in the form of hybrid metal-composite square tubes which have the potential to provide cost-effective structures for energy absorption applications. The behavior of these elements is complicated, requiring computationally intensive and time-consuming computer simulations to analyze their failure and to improve their design. The time required for these simulations may lead to long times before new elements are introduced into the marketplace. Consequently, the objective of this study is to provide an efficient and fast methodology to obtain the best hybrid structures for crashworthiness applications. To support the computational modeling, experimental results obtained from the samples with different configurations tested under quasi-static compression loading were used to validate the models. The effect of fiber orientation, stacking sequence, and thickness of the composite on energy absorption and failure modes were predicted using the models. To reduce the time associated with computational modeling, artificial neural networks (ANNs) were employed to fit the response at selected training points and to generate a pool of responses at other points. These responses may then be used by a designer to choose the best solution for a set of competing design constraints.
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The stars in our eyes: representations of the Square Kilometre Array telescope in the South African mediaGastrow, Michael 03 1900 (has links)
Thesis (PhD)--Stellenbosch University, 2015. / AFRIKAANSE OPSOMMING : Die vierkantkilometer-radioteleskoop SKA (―Square Kilometre Array‖) sal na verwagting die grootste teleskoop op aarde en die grootste wetenskapprojek in Afrika wees. Hierdie verhandeling konsentreer op hoe die SKA vanaf September 2011 tot Augustus 2012 in die Suid-Afrikaanse media uitgebeeld is. Dit handel oor die leemtes in die literatuur oor wetenskapkommunikasie, veral wat betref wetenskapkommunikasie in Afrikaverband. Deur uit massa- en wetenskapkommunikasieteorie te put, modelleer die studie kommunikasieprosesse en -uitsette met behulp van ‘n konseptuele raamwerk wat op die gedagte van die openbare sfeer berus. Die navorsing word in die besonder onderstut deur onderhoude met sleutelinformante en die ontleding van nuus- en sosiale media.
Die wetenskapkommunikasie oor die SKA gedurende hierdie tydperk was stelselmatig gekenmerk deur ‘n hoë vlak van koördinasie tussen die aansporings, strategieë en strukture van alle hoofrolspelers oor die kommunikasiestelsel heen. Al die hoofrolspelers buite die media het die SKA op so ‘n manier in die openbare sfeer probeer uitbeeld dat dit openbare steun sou werf. Primêre hekwagterfunksies is aan die voorste SKA-organisasie- en openbaresektor-rolspelers toegewys, maar was verder afgewentel binne universiteite. Hekwagterfunksies in die media is hoofsaaklik deur nuuswaarde sowel as institusionele kultuur en organisatoriese kenmerke bepaal. Verhoudings tussen wetenskaplikes en joernaliste was oënskynlik oor die algemeen positief en gegrond op vertroue. Die beduidendste bron van inligting vir joernaliste was die SKA self, gevolg deur rolspelers in die openbare sektor. Tog is ander rolspelers, bepaald plaaslike belanghebbendes, gemarginaliseer. Die Afrikaanstalige media het veral onder plaaslike gemeenskappe ‘n belangrike rol gespeel en het meer dikwels as ander oor die SKA berig. Die sosiale media het die SKA merendeels op ‘n soortgelyke wyse as die nuusmedia hanteer, maar die struktuur van kommunikasie-uitsette is beïnvloed deur die kenmerkende eienskappe van sosiale media self, waaronder die virale verspreiding van boodskappe en hoër vlakke van vryewilsoptrede (―agency‖) deur individuele rolspelers. Tog was daar aanduidings van beduidende media-integrasie, in die sin dat groot Suid-Afrikaanse mediahuise die bron was van die meeste boodskappe in sowel die nuus- as sosiale media. / ENGLISH ABSTRACT : The Square Kilometre Array (SKA) radio telescope is set to become the largest telescope on Earth, and also the largest science project in Africa. This dissertation focuses on the manner in which the SKA was represented in the South African media from September 2011 to August 2012. This addresses gaps in the literature on science communication, particularly with respect to science communication in an African context. By drawing on mass communication theory and science communication theory, it models communication processes and outputs using a conceptual framework based on the notion of the public sphere. Empirically, the study is underpinned by key informant interviews and the analysis of news media and social media content.
Systemically, the science communication of the SKA during this period was characterized by a high level of alignment of incentives, strategies, and structures across the main actors in the communication system. Main actors outside the media all aimed to position the SKA in the public sphere in a manner that would grow public support. Primary gatekeeping functions were positioned at the apex of the SKA organisation and public sector actors, but were more devolved within universities. Gatekeeping in the media was primarily driven by news value, as well as institutional culture and organisational attributes. Relationships between scientists and journalists were found to be generally positive and trust-based. The most significant source of information for journalists was the SKA itself, followed by public sector actors. However, other actors were marginalized, particularly local stakeholders. The Afrikaans language media played an important role, particularly among local communities, and published about the SKA relatively more often. The social media represented the SKA in a broadly similar manner to the news media, but the structure of communication outputs was influenced by the distinct attributes of the social media, including the viral propagation of messages and higher levels of agency by individual actors. However, there were indications of substantial media integration, in that major South African media corporations were the source of the majority of messages in both the news and social media.
The tone of media outputs was largely neutral or positive, framing the SKA as a 'good news story‘. The overarching dominant frame for representing the SKA was the site allocation process, in which South Africa and Australia competed in a bid to host the telescope for the international SKA consortium. Science and technology aspects of the project constituted the second most common framing, within which the search for extra-terrestrial intelligence was the most commonly represented research question. Representations of technological aspects of the SKA were generally shallow, with most articles mentioning only one aspect of the project‘s technology.
The SKA was also constructed as a symbol, representing an instance of African scientific and technological achievement, African participation in globalized science, and a refutation of Afro-pessimism. The impact of the SKA on the public imagination, and the public sphere, was thus clearly far wider and deeper than only its science and technology accomplishments and contributions.
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Fractal grid-turbulence and its effects on a performance of a model of a hydrokinetic turbineMahfouth, Altayeb 04 January 2017 (has links)
This thesis focuses on generating real world turbulence levels in a water tunnel rotor test using fractal grids and characterizing the effect of the fractal grid generated-turbulence on the performance of hydrokinetic turbines. The research of this thesis is divided into three studies: one field study and two laboratory studies. The field study was conducted at the Canadian Hydro Kinetic Turbine Test Centre (CHTTC) on the Winnipeg River. An Acoustic Doppler Velocimeter (ADV) was used in the field study to collect flow measurements in the river. The laboratory studies were conducted at the University of Victoria (UVic) fluids research lab and the Sustainable Systems Design Lab (SSDL). In addition, the Particle Image Velocimetry (PIV) technique was used in the experiential studies to obtain quantitative information about the vector flow field along the test section, both upstream and downstream of the rotor’s plane.
The first study is a field study aiming to provide real flow characteristics and turbulence properties at different depths from the free-surface to boundary layer region of a fast river current by conducting a field study in the Winnipeg River using ADV. A novel technique to deploy and control an ADV from free-surface to boundary layer in a fast-current channel is introduced in this work. Flow characteristics in the river, including mean flow velocities and turbulence intensity profiles are analyzed. The obtained results indicate that the maximum mean velocity occurs below the free-surface, suggesting that the mean velocity is independent of the channel depth. From the free-surface to half depth, it was found that changes in both the mean velocity and turbulence intensity are gradual. From mid-depth to the river bed, the mean velocity drops rapidly while the turbulence intensity increases at a fast rate. The turbulent intensity varied from 9% at the free-surface to around 17.5% near the river bed. The results of this study were used in the second lab study to help designing a fractal grid for a recirculating water flume tank. The goal was to modify the turbulence intensity in the water tunnel such that the generated turbulence was similar to that in the river at a location typical of a hydrokinetic device. The properties of fractal-generated turbulence were experimentally investigated by means of 2D Particle Image Velocimetry (PIV). The streamwise turbulent intensity profiles for different grids along the channel are presented. Additionally, visualization of the average and fluctuating flow fields are also presented. The results are in good agreement with results in literature. The third and final study investigated the power coefficient of a scale hydrokinetic turbine rotor in controlled turbulent flow (7.4 % TI), as well as in the low-turbulence smooth flow (0.5% TI) typical of lab scale testing. PIV was employed for capturing the velocity field. The results show that using realistic TI levels in the water tunnel significantly decrease the turbine’s power coefficient compared to smooth flow, highlighting the importance of considering this effect in future experimental campaigns. / Graduate
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Studium elektrochemického chování kyseliny tauroursodeoxycholové na elektrodách na bázi rtuti / Study of electrochemical behaviour of tauroursodeoxycholic acid at mercury-based electrodesPišnová, Kateřina January 2016 (has links)
This thesis deals with electrochemical behaviour of tauroursodeoxycholic acid (TUDCA) at silver solid amalgam electrode modified by mercury meniscus (m-AgSAE), polished silver solid amalgam electrode (p-AgSAE) and hanging mercury dropping electrode (HMDE). This thesis is a part of a bigger scientific research that deals with synthesis and characterization of supramolecular systems based on natural steroid compounds and its conjugates. TUDCA offers one reduction peak at m-AgSAE in the environment of Britton - Robinson buffer in range of pH 6.0 - 13.0. The potential of this peak is around −1200 mV. Using cyclic voltammetry was determined that the process on the electrode surface is quasireversible, the reduction is controlled by diffusion and the anodic process is controlled by adsorption. Concentration dependence measured at HMDE by direct current voltammetry in 0.04 mol∙l-1 borat buffer (pH 9.1) is linear in two concentration intervals - 1∙10-3 - 2∙10-4 mol∙l-1 and 1∙10-4 - 8∙10-6 mol∙l-1 of TUDCA. There was no linear dependence between the increase of concentration of TUDCA and the height of the peak obtained on amalgam electrodes by methods DC, DP, cyclic and "square-wave" voltammetry. On HMDE was in several short concentration intervals measured by a CV method a linear dependence of cathodic and...
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Jednoduchý elektrochemický DNA biosenzor pro detekci poškození DNA způsobeného UV zářením / Simple Electrochemical DNA Biosensor for Detection of DNA Damage Caused by UV RadiationArustamian, Daria January 2018 (has links)
Ultraviolet (UV) radiation is a common DNA damaging agent. Major DNA lesions, such as cyclobutane pyrimidine dimers (CPDs) and pyrimidine-(6-4)-pyrimidone (6-4PPs) photoproducts, are carcinogenic and mutagenic. UV induced DNA damage was investigated using a simple electrochemical DNA biosensor based on an ultra-trace graphite electrode (UTGE) and low molecular weight doble-stranded DNA (dsDNA) from salmon sperm. Biosensor was prepared using adsorption of dsDNA on a surface of the UTGE and then used to detect UV-induced DNA damage. Effects of UV radiation were investigated using a combination of several electrochemical technics: square-wave voltammetry (SWV) for direct monitoring of DNA base oxidation and cyclic voltammetry (CV) and electrochemical impedance spectroscopy (EIS), as non-direct methods, using redox-active indicator [Fe(CN)6]4-/3- . CV and EIS, which allow characterization of electrode surface, were used to optimize preparation of the dsDNA/UTGE biosensor. Prepared dsDNA/UTGE biosensor was exposed to UV radiation using UV lamp with two set wavelengths: UVC of 254 nm and UVA of 365 nm. UVC radiation was used to damage DNA. Relative signal decrease was 50% after 20 minutes of exposure to UVC radiation. UVA radiation was used to compare effects of different types of UV radiation. Obtained...
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Att äta kakan och ha den kvar : En studie om universitetsstudenters medvetenhet, attityd, och beteende gällande cookiesJonasson, Fanny, Oskarsson, Amanda January 2019 (has links)
Cookies är idag ett utbrett fenomen som nyttjas vid digital insamling av information. Informationen som samlas in är ofta av personlig karaktär och används bland annat för att individanpassa användarupplevelser på webbsidor. Ovissheten kring digital insamling av personlig information skapar en oro som idag är mycket omdebatterad. Detta arbete utgörs av en kvantitativ studie med syfte att undersöka möjliga samband mellan universitetsstudenters medvetenhet, attityd och beteende gällande digital insamling av information. Undersökningen består av en onlinebaserad enkät. Det insamlade materialet har analyserats utifrån det teoretiska ramverket Communication Privacy Management (CPM) med hjälp av analysmetoden Partial Least Squares (PLS) samt IBM Statistical Package for Social Sciences (SPSS) för att finna relevanta samband. Resultat påvisade att majoriteten universitetsstudenter känner till fenomenet cookies, men färre känner till dess användningsområden. Det konstaterades även att medvetenhet kring cookies har en påverkan på både beteende och attityd. Det fastställdes även att oavsett om universitetsstudenter har en negativ attityd förändras inte dess beteende. / Cookies are a widespread phenomenon and the main technique for digital collection of information. The collected information is often of personal nature and is used, among other things, to personalize user experiences on web pages. The uncertainty regarding digital collection of personal information creates privacy concerns that is significantly debated today. This essay consists of a quantitative study with the aim to investigate possible relations between university students awareness, attitude and behaviour regarding digital collection of information. The survey consist of an online-based poll. The gathered material has been analyzed by the theoretical framework Communication Communication Management (CPM) with the analysis method Partial Least Squares (PLS) and the IBM Statistical Package for Social Sciences (SPSS) to find relevant relations. Results showed that the majority of university students are familiar with the phenomenon of cookies, but few are aware of its area of use. It was also found that awareness of cookies has an influence on both behaviour and attitude. It can be established that regardless of whether university students have a negative or positive attitude regarding cookies, it does not affect their behaviour.
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Natálie Gorbaněvská v české recepci a překladech / Natalya Gorbanevskayaʼs reception and translation in the Czech RepublicVaňková, Zuzana January 2019 (has links)
The present diploma thesis investigates Czec sociopolitical and translation reception of poet, journalist and dissident Natalya Gorbanevskaya. The thesis bases on the context from the Moscow Red Square demonstration against the occupation of Czechoslovakia in August 1968 and maps its reception, which is above all in the Czech Republic an inseparable part of the image of this personage. Further, it introduces the life, literary output and poetics of Gorbanevskaya and makes translatological analysis of Czech translations of authorial parts from her book Red Square at Noon, cycle of eight-line-poems "Place de la non-Concorde" (Площадь несогласия) and other particular poems. Inseparable part of the thesis is also an interview with the author of Czech translations Milan Dvořák.
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