<p>The prevalence of non-communicable diseases such as hypertension and diabetes including obesity has increased among the black population over the past few years. The increase in these diseases has been associated with increased urbanization and lifestyle changes. No studies have documented the experiences of people who have migrated to urban areas. Aim: To describe the type of lifestyle changes, reasons for the lifestyle changes and the barriers to adopting a healthy lifestyle among people who have migrated from rural areas to urban areas in the past 5 years and reside in Khayelitsha. Objectives: (1) To identify people who have moved from rural to urban areas in the past 2-5 years / (2) To explore reasons for moving to the city / (3) To explore experiences of respondents on moving to the city / (4) To identify the types of lifestyle changes related to chronic diseases among respondents on arrival to the city / (5) To identify reasons for the lifestyle changes among respondents / (6) To identify coping strategies that have been adopted by respondents / (7) To identify barriers to healthy lifestyle among respondents / (8) To make recommendations for development of appropriate interventions that will enable migrating populations to adjust better to city life.</p> <p>Rural-urban migration (urbanization) was associated with factors such as seeking employment, better life and working opportunities. On arrival in the city migrants face a number of challenges such as inability to secure employment and accommodation. Faced with these challenges, migrants change their lifestyle including buying fatty foods, increasing frequency in food consumption and decreasing in physical activity. In the city factors such as poverty, environment including lack of infrastructure, and lack of knowledge about nutrition, social pressures and family preferences were identified as hindrances to a healthy lifestyle. Conclusion: This study identified various factors that influence the decision to migrate from rural areas. Lifestyle changes in an urban setting are due to socio-economic, environmental and individual factors. Perceived benefits of moving to urban areas can pose challenges to health and this may have negative health-outcomes.</p>

<p>The prevalence of non-communicable diseases such as hypertension and diabetes including obesity has increased among the black population over the past few years. The increase in these diseases has been associated with increased urbanization and lifestyle changes. No studies have documented the experiences of people who have migrated to urban areas. Aim: To describe the type of lifestyle changes, reasons for the lifestyle changes and the barriers to adopting a healthy lifestyle among people who have migrated from rural areas to urban areas in the past 5 years and reside in Khayelitsha. Objectives: (1) To identify people who have moved from rural to urban areas in the past 2-5 years / (2) To explore reasons for moving to the city / (3) To explore experiences of respondents on moving to the city / (4) To identify the types of lifestyle changes related to chronic diseases among respondents on arrival to the city / (5) To identify reasons for the lifestyle changes among respondents / (6) To identify coping strategies that have been adopted by respondents / (7) To identify barriers to healthy lifestyle among respondents / (8) To make recommendations for development of appropriate interventions that will enable migrating populations to adjust better to city life.</p> <p>Rural-urban migration (urbanization) was associated with factors such as seeking employment, better life and working opportunities. On arrival in the city migrants face a number of challenges such as inability to secure employment and accommodation. Faced with these challenges, migrants change their lifestyle including buying fatty foods, increasing frequency in food consumption and decreasing in physical activity. In the city factors such as poverty, environment including lack of infrastructure, and lack of knowledge about nutrition, social pressures and family preferences were identified as hindrances to a healthy lifestyle. Conclusion: This study identified various factors that influence the decision to migrate from rural areas. Lifestyle changes in an urban setting are due to socio-economic, environmental and individual factors. Perceived benefits of moving to urban areas can pose challenges to health and this may have negative health-outcomes.</p>

Thesis (M.Sc.) (Applied Mathematics) --University of Limpopo, 2008. / In this dissertation, two non-linear mathematical models are proposed and analyzed to investigate the spread of infectious diseases in a variable size population through horizontal transmission in the presence of preventive or therapeutic vaccines which are capable of inducing temporary immunity and wane in time. In modeling the transmission dynamics, the population is divided into three subclasses namely; Susceptibles, Infectives and Vaccinated groups. It is assumed that both Vaccinated and Susceptible individuals are recruited into the community and can only become infected via contacts with the infectives group but the rate at which the vaccinated group may contract the diseases is extremely very low depending on the efficacy of the vaccine. All infectives are assumed to move at a constant rate to both Vaccinated and Susceptible groups. These models are analyzed by using the stability theory of differential equations and numerical simulation. The models exhibit two equilibria namely; the disease-free and the endemic equilibria. It is shown that if the vaccination reproduction number R0 < 1, the disease-free equilibrium is always globally asymptotically stable and in such a case the endemic equilibrium does not exist and the disease can be totally eliminated in the community. However, if R0 > 1, a unique endemic equilibrium exists that is locally asymptotically stable and consequently the equilibrium values of infective, vaccinated and susceptible population can be maintained at desired levels. Numerical simulations implemented on MAPLE using both Adomian decomposition technique and Runge-Kutta integration schemes, support our analytical conclusions and illustrate possible behaviour scenarios of the models. / International Pentecostal Holiness Church, Limpopo Provincial Treasury, National Student Financial Aid Scheme and National Research Foundation

The pace at which change is occurring in the life of human beings, due to technological advancement, could be described as logarithmic. This fast-paced change is not just of consequence to the individual, but to countries, governments, companies, big and small systems like villages and sports clubs and the like, as well. This study case was inspired by the fact that what was a little-known threat yesterday, could suddenly become a crippling matter. It is, therefore, critical for individuals and businesses to consider risk not just in the usual context but with an open mind. This is especially true for systems in the Third World or developing nations where evolutionary stages of advancement and development are known to have been skipped due to forced or influenced adoption by the advanced or First World dictates. An example is the adoption of Carbon Emission Minimisa tion Pacts that have also been mooted for developing nations, even though their participation in causing the past Industrial Revolution pollution was minimal. A small operation in the Eastern Cape may, today, see no need to attract an overseas customer, not realising that the local customer may enter a merger or be bought out by an international organisation which would demand international protocols on the local supplier. Such is the risk with Globalisation. Local businesses should embrace global competitive practices for sustainability in the global business arena that is surely upon the business place today and the short term. South African businesses are no longer protected by the country borders, or the government and political systems such as the apartheid-born sanctions and tariff regimes. The objective of this study of Legionella bacteria risk management by business firms in the Eastern Cape (East London and Border Areas) is to obtain an insight into how they fare on one of the risks that, in Europe, is legislated and, in many parts of the First World, is regarded as fundamental. Beside the globalisation issues mentioned above, the South African workforce has been noted as highly affected by HIV and TB, which are symptomatic of people susceptible to Legionnaire‟s Disease. The high cost and skills shortage in the South African industry demand great care in order to prevent further loss, due to sick absenteeism or the death of workers. The study included a comprehensive literature review of issues around Legionella bacteria in industrial operations and how ill effects could be prevented and managed. A questionnaire was then drawn up and used to check for awareness, capability and ascertain what motivational factors could influence Legionella risk management by businesses in the geographical study area. All businesses with facilities utilising water cooling towers, safety showers, waste water treatment plants, humidifier air conditioning and water fountains, were presented with the questionnaire. A 56 percent return was achieved and responses were processed and analysed using Microsoft Excel on a Windows XP computer package. The findings showed that there was a poor awareness of Legionella bacteria and the risk they posed, a factor that may be used to explain the poor questionnaire returns. The capability assessment also showed a weak status. Legislation, proof of outbreak and fines were determined as effective would-be motivators for full Legionella risk management. The study concluded with recommendations for awareness programmes by interested bodies like the Legionella Action Group, Department of Labour and companies providing Legionella consulting services. While legislation and, therefore, fines, were not yet applied in South Africa, the drive for employee and community welfare should be adequate motivating factors for businesses to manage Legionella risk. Foreign capital inflow into the South African economy was also a factor that should be considered by businesses that looked to expand and need to access these funds through mergers or acquisitions. These funds would require financial as well as technical audits that show adequate risk protection.

MENVSC (Geography) / Department of Geography and Geo-Information Sciences / Semi-arid regions of Africa are prone to epidemics of malaria. Epidemic malaria occurs along the geographical margins of endemic regions, when the equilibrium between the human, parasite and mosquito vector populations are occasionally disturbed by changes in one or more meteorological factors and a sharp but temporary increase in disease incidence results. Monthly rainfall and temperature data from the South African Weather Service and malaria incidence data from Department of Health were used to determine the influence of meteorological variables on malaria transmission in Limpopo from 1998-2014. Meteorological influences on malaria transmission were analyzed using time series analysis techniques. Climate suitability for malaria transmission was determined using MARA distribution model. There are three distinct modes of rainfall variability over Limpopo which can be associated with land falling tropical cyclones, cloud bands and intensity of the Botswana upper high. ENSO and ENSO-Modoki explains about 58% of this variability. Malaria epidemics were identified using a standardized index, where cases greater than two standard deviations from the mean are identified as epidemics. Significant positive correlations between meteorological variables and monthly malaria incidence is observed at least one month lag time, except for rainfall which shows positive correlation at three months lag time. Malaria transmission appears to be strongly influenced by minimum temperature and relative humidity (R = 0.52, p<0.001). A SARIMA (2, 1, 2) (1, 0, 0)12 model fitted with only malaria cases has prediction performance of about 53%. Warm SSTs of the SWIO and Benguela Niño region west of Angola are the dominant predictors of malaria epidemics in Limpopo in the absence of La Niña. Warm SSTs over the equatorial Atlantic and Benguela Niño region results in the relaxation of the St. Helena high thus shifting the rainy weather to south-east Africa. La Niña have been linked with increased malaria cases in south-east Africa. During El Niño when rain bearing systems have migrated east of Madagascar ridging of the St. Helena high may produce conducive conditions for malaria transmission. Anomalously warmer and moist winters preceding the malaria transmission season are likely to allow for high mosquito survival and the availability of the breeding sites thus high population in the beginning of the transmission season hence resulting in increased epidemics. / NRF

Diarrhoea, particularly infectious diarrhoea, in children below five years of age is recognised as one of the leading cause of morbidity and mortality throughout the world. This is especially true in residential areas of developing countries where there is substandard sanitation and overcrowding which are reservoirs for farther transmission. Shigellosis is endemic in developing countries and in Sub-Saharan Africa, including South Africa, a region where unique geographic, economic, political, sociocultural, and personal factors interact to create distinctive continuing challenges to prevention and control. Our study was undertaken to establish baseline information on incidences of Shigella, its serotype and resistant pattern of isolates from human faeces from residents of Johannesburg, South Africa. All stools received from January to April 2013 from the private health care system were cultured on standard media for isolation of Shigella and confirmed by standard biochemical reactions and serological method. Antibiotic sensitivity test was determined by the agar diffusion method. 11009 stool samples were assayed from patients aged between 22 days to 94 years with a 110 Shigella isolates yield, of which 47 (43%) were S. flexneri, 61 (55%) S. sonnei and 1 (1%) of S. dysentriae and S. boydii respectively. Majority of patients 76 (69%) were children between < 1 to 5 years old followed by those between 6 to 10 years 13(12%). Of the four species isolated from children of up to 10 years old, S. sonnie was confirmed in 52 cases (59%) and S. flexneri in 36 cases (41%). A total of 53 (48%) males and 57 (52%) females were infected. However, a hundred per cent susceptibility to ciprofloxacin and ceftriaxone but high levels of resistance to Co-trimoxazole (83%), tetracycline (72%), and ampicillin (26%) was noted. From the 110 isolates, 96 (87%) were resistant to one or more drugs while 14 (13%) were fully susceptible. These results show that S. sonnei followed by S. flexneri as predominating aetiology of shigellosis and Ceftriaxone and ciprofloxacin as effective drugs against all four Shigella species. / Health Studies / M. Sc. (Life Sciences)

Diarrhoea, particularly infectious diarrhoea, in children below five years of age is recognised as one of the leading cause of morbidity and mortality throughout the world. This is especially true in residential areas of developing countries where there is substandard sanitation and overcrowding which are reservoirs for farther transmission. Shigellosis is endemic in developing countries and in Sub-Saharan Africa, including South Africa, a region where unique geographic, economic, political, sociocultural, and personal factors interact to create distinctive continuing challenges to prevention and control. Our study was undertaken to establish baseline information on incidences of Shigella, its serotype and resistant pattern of isolates from human faeces from residents of Johannesburg, South Africa. All stools received from January to April 2013 from the private health care system were cultured on standard media for isolation of Shigella and confirmed by standard biochemical reactions and serological method. Antibiotic sensitivity test was determined by the agar diffusion method. 11009 stool samples were assayed from patients aged between 22 days to 94 years with a 110 Shigella isolates yield, of which 47 (43%) were S. flexneri, 61 (55%) S. sonnei and 1 (1%) of S. dysentriae and S. boydii respectively. Majority of patients 76 (69%) were children between < 1 to 5 years old followed by those between 6 to 10 years 13(12%). Of the four species isolated from children of up to 10 years old, S. sonnie was confirmed in 52 cases (59%) and S. flexneri in 36 cases (41%). A total of 53 (48%) males and 57 (52%) females were infected. However, a hundred per cent susceptibility to ciprofloxacin and ceftriaxone but high levels of resistance to Co-trimoxazole (83%), tetracycline (72%), and ampicillin (26%) was noted. From the 110 isolates, 96 (87%) were resistant to one or more drugs while 14 (13%) were fully susceptible. These results show that S. sonnei followed by S. flexneri as predominating aetiology of shigellosis and Ceftriaxone and ciprofloxacin as effective drugs against all four Shigella species. / Health Studies / M. Sc. (Life Sciences)

MPH / Department of Public Health

MPH / Department of Public Health / See the attached abstract below

Since the earliest reported cases of HIV/AIDS probably in 1959 in Africa, there has been a consistent progression in the new HIV/AIDS infection cases. In South Africa, Gauteng, records one of the highest HIV/AIDS prevalence rates in the country. The Department of Health (DOH) South Africa conducts ongoing studies on HIV/AIDS at provincial levels; these studies monitor the prevalence of HIV/AIDS amongst pregnant women attending antenatal clinics, as a tool for determining and monitoring the prevalence, trends, patterns and spread of the disease in the general population. This study analyses sentinel and spatial data collected from the (DOH) and Statistics South Africa (StatsSA) respectively, and depicts them in the form of spatial maps, and then critically analyses the spatial patterns that occur. The research findings would hopefully contribute to the overall knowledge of HIV/AIDS and provide framework and relevant literature for further investigation. / Geography / M.Sc. (Geography)