Modern readings of the Tractatus focus on the concept of nonsense instead of the meta-physics presented in the book. In fact a resolute reading sees the body of the system as mere nonsense and calls it a “ladder that should be thrown away”[1]. Other readings have seen the Tractatus as conveying knowledge-how[2] and some have seen the work as to be illustrating limitation of doctrinal systems such as the Mosaic Law[3]. In this paper it is argued that the Tractatus can be read as leading to a reductio ad absurdum read in its context. A reductive reading is presented that interprets the purpose of the book as conveying a method that can be used to defeat skepticism. The concept of nonsense as developed in the Tractatus is crucial for this understanding. It turns out that you can in fact discard the meta-physics of the book since when you have defeated skepticism you have come to a solid place. There is a way to determine the truth-value of all propositions about the world. Thus a resolute reading of the Tractatus is confirmed, when it comes to the meta-physical content, but the book still conveys knowledge how. [1] Cora Diamond, “Throwing away the ladder”, Philosophy, Volume 63 (243), pp. 5-27, 1998. [2] Adrian W. Moore and Peter Sullivan, “Ineffability and Nonsense”, Aristotelian Society Supplementary, Volume 77, pp. 169-223, 2003. [3] Michael Kremer, “The Purpose of Tractarian Nonsense”, Noûs, Volume 35, pp. 39-73, 2001.

Este trabalho tem como base os aportes da teoria psicanalítica, mais precisamente, a idéia de nonsense situada nos três registros desenvolvidos por Lacan: o imaginário, o simbólico e o real. Para isso, procede uma articulação entre a Psicanálise e a Arte, destacando a literatura de Lewis Carroll em seus dois livros: As aventuras de Alice no País das Maravilhas e Através do espelho. A obra de Carroll foi endereçada às meninas, e sua relação com elas foi objeto de estudo de muitos pesquisadores, os quais buscaram destacar um possível desvio de seu comportamento sexual. Sem nos pautar em qualquer patologia, percorremos a relação de amor transferencial como sendo a condição para o surgimento da obra. Carroll, em sua escrita, evidencia uma série de verdades sólidas, embora não evidentes, como bem aponta Lacan. A verdade, na obra de Carroll, é da ordem do nonsense, pois se refere ao Real. Desse modo, Lacan avança sobre uma tendência da Psicanálise que buscava encontrar uma verdade por trás dos sintomas e de outras formações do inconsciente. Essa tendência vinha transformando a Psicanálise em um psicologismo analítico. A verdade apontada por Lacan se apresenta como um fundo opaco, sobre o qual toda a realidade se constrói como um anteparo fantasmático erguido contra a inconsistência do Outro. O País das Maravilhas que Alice encontra é repleto de seres estranhos e de situações bizarras, sobre os quais ela tenta impor o seu saber adquirido previamente, até perceber que o nonsense é a variável estável. O nonsense comparece nos registros que constituem o sujeito, mostrando que as identificações não são estáveis, que o simbólico é repleto de equívocos e que o real é sem lei. Por fim, discutiu-se como tal situação comparece na educação de maneira geral, observando-se que os professores têm mais condições de lidar com a pluralidade das situações, quando sustenta uma posição não-toda, pois, a cada novo impasse, precisam rever a sua lógica. Alice pode ensinar a educação a não recuar diante do Real. / This work is based on the contributions of the psychoanalytic theory, more specifically on the concept of nonsense found in the 3 realms developed by Lacan: imaginary, symbolic, and real. It creates a link between Psychoanalysis and Art, highlighting the work of Lewis Carroll by two of his books: Alice\'s Adventures in Wonderland and Through the Looking-Glass and What Alice Found There. The work of Lewis Carroll was aimed at the girls, and the relationship between the girls with him has been the target of studies by many researchers, who have tried to identify a sexual deviation in Mr. Carroll. Avoiding the pathology subject matter, we cover the transferential-love relationship as the condition for the creation of the books. Through his writings, Mr. Carroll brings to the surface a series of solid truths, albeit not evident, as well stated by Lacan. Truth in the books of Lewis Carroll follows the nonsense order, since it refers to the Real. This is how Lacan addressed the psychoanalytical tendency that sought to find truth in the symptoms and other unconscious structures, a tendency that was transforming psychoanalysis on an analytical psychologism. The truth identified by Lacan presents itself as the opaque background onto which reality builds itself as a spectral shield erected against the inconsistencies of the Other. Alice finds a wonderland full of strange beings and bizarre situations, upon which she tries to impose her previously acquired knowledge, until she realizes that the nonsense is the fixed variable. The nonsense manifests itself on the records that constitute the subject, demonstrating that the identifications are unstable, that the symbolic is filled with inaccuracies, and that the real follows no laws. Finally, we argue how such state of things manifests itself in education in general, through the observation that teachers possess the ability of dealing with the plurality of situations, when attempting to support a position that is non-whole, as every new dead-locked situation forces the teachers to revaluate their logic. Alice can teach education to stand ground when facing the Real.

Este trabalho tem como base os aportes da teoria psicanalítica, mais precisamente, a idéia de nonsense situada nos três registros desenvolvidos por Lacan: o imaginário, o simbólico e o real. Para isso, procede uma articulação entre a Psicanálise e a Arte, destacando a literatura de Lewis Carroll em seus dois livros: As aventuras de Alice no País das Maravilhas e Através do espelho. A obra de Carroll foi endereçada às meninas, e sua relação com elas foi objeto de estudo de muitos pesquisadores, os quais buscaram destacar um possível desvio de seu comportamento sexual. Sem nos pautar em qualquer patologia, percorremos a relação de amor transferencial como sendo a condição para o surgimento da obra. Carroll, em sua escrita, evidencia uma série de verdades sólidas, embora não evidentes, como bem aponta Lacan. A verdade, na obra de Carroll, é da ordem do nonsense, pois se refere ao Real. Desse modo, Lacan avança sobre uma tendência da Psicanálise que buscava encontrar uma verdade por trás dos sintomas e de outras formações do inconsciente. Essa tendência vinha transformando a Psicanálise em um psicologismo analítico. A verdade apontada por Lacan se apresenta como um fundo opaco, sobre o qual toda a realidade se constrói como um anteparo fantasmático erguido contra a inconsistência do Outro. O País das Maravilhas que Alice encontra é repleto de seres estranhos e de situações bizarras, sobre os quais ela tenta impor o seu saber adquirido previamente, até perceber que o nonsense é a variável estável. O nonsense comparece nos registros que constituem o sujeito, mostrando que as identificações não são estáveis, que o simbólico é repleto de equívocos e que o real é sem lei. Por fim, discutiu-se como tal situação comparece na educação de maneira geral, observando-se que os professores têm mais condições de lidar com a pluralidade das situações, quando sustenta uma posição não-toda, pois, a cada novo impasse, precisam rever a sua lógica. Alice pode ensinar a educação a não recuar diante do Real. / This work is based on the contributions of the psychoanalytic theory, more specifically on the concept of nonsense found in the 3 realms developed by Lacan: imaginary, symbolic, and real. It creates a link between Psychoanalysis and Art, highlighting the work of Lewis Carroll by two of his books: Alice\'s Adventures in Wonderland and Through the Looking-Glass and What Alice Found There. The work of Lewis Carroll was aimed at the girls, and the relationship between the girls with him has been the target of studies by many researchers, who have tried to identify a sexual deviation in Mr. Carroll. Avoiding the pathology subject matter, we cover the transferential-love relationship as the condition for the creation of the books. Through his writings, Mr. Carroll brings to the surface a series of solid truths, albeit not evident, as well stated by Lacan. Truth in the books of Lewis Carroll follows the nonsense order, since it refers to the Real. This is how Lacan addressed the psychoanalytical tendency that sought to find truth in the symptoms and other unconscious structures, a tendency that was transforming psychoanalysis on an analytical psychologism. The truth identified by Lacan presents itself as the opaque background onto which reality builds itself as a spectral shield erected against the inconsistencies of the Other. Alice finds a wonderland full of strange beings and bizarre situations, upon which she tries to impose her previously acquired knowledge, until she realizes that the nonsense is the fixed variable. The nonsense manifests itself on the records that constitute the subject, demonstrating that the identifications are unstable, that the symbolic is filled with inaccuracies, and that the real follows no laws. Finally, we argue how such state of things manifests itself in education in general, through the observation that teachers possess the ability of dealing with the plurality of situations, when attempting to support a position that is non-whole, as every new dead-locked situation forces the teachers to revaluate their logic. Alice can teach education to stand ground when facing the Real.

There is no abstract available for this thesis.

No description available.

ARS2 is a member of the nuclear cap-binding complex (CBC) that is critical for a number of RNA processing pathways. The emerging model is that ARS2 acts as a master regulator of RNAPII transcript maturation by bringing capped RNA substrates together with the appropriate processing machinery. ARS2 is essential for early mammalian development but it remains unclear precisely how ARS2 functions in stem and progenitor cell maintenance and differentiation. The purpose of this study was to answer basic questions about the localization and function of ARS2 in muscle progenitor cells. Here I describe the localization of ARS2 in proliferating myoblasts and post-mitotic differentiating myotubes and show that disruption of ARS2 expression levels by knockdown or overexpression results in impaired myogenic differentiation. I also discovered a new isoform of ARS2 that is localized exclusively in the cytoplasm and found preliminary evidence that ARS2 is required for nonsense-mediated decay (NMD). This study includes the first evidence that an ARS2 isoform is expressed in the cytoplasm and opens the door for the discovery of new ARS2 functions beyond its reported roles in the nucleus. / Graduate

The subject of this thesis is primarily the ethical point of Wittgenstein’s Tractatus. In the work, Wittgenstein investigates the connection between ethics and the world by examining the nature of the proposition. In the Lecture on Ethics, Wittgenstein reinvestigates this connection more directly by explaining the nature of the ethical expression. I argue that the ethical point of the book is to help one to understand the ephemeral characteristics of ethics insofar as they cannot be articulated by demonstrating what can be articulated. In the Lecture, Wittgenstein also points to a deep challenge encountering the Tractarian pictorial language. Logic reminds us that we are held captive by pictorial language and could never get outside it. Ethics, on the other hand, is a constant attempt to get outside of it by usage of simile. Although this attempt seems to be hopeless, it is unavoidable and significant. It characterizes the human condition.

Made available in DSpace on 2014-06-12T16:31:52Z (GMT). No. of bitstreams: 2 arquivo4771_1.pdf: 2869990 bytes, checksum: 19425c61b0c5ecd990f1dc262a86e934 (MD5) license.txt: 1748 bytes, checksum: 8a4605be74aa9ea9d79846c1fba20a33 (MD5) Previous issue date: 2007 / A presente dissertação tem como objetivo analisar a rede de relacionamentos Orkut, criada em janeiro de 2004 pelo Google, e amplamente aceita pelos brasileiros. Nosso intuito foi observá-la, sobretudo, através de uma de suas características mais fortes, a saber, o lúdico. Para tanto, interessou-nos atentar para os chamados perfis fakes (falsos) que compõem os mais de trinta milhões de membros da supracitada rede, numa alusão a alguns romances oitocentistas escritos por meio de cartas, os quais se valeram de estratégia semelhante; bem como para uma possível comparação entre a subjetividade dos indivíduos do século XVIII e os da contemporaneidade. Por fim, discutimos a questão da moral conforme expressa através das relações entre os membros e comunidades do Orkut. Preocupamo-nos com a epistemologia de alguns termos empregados, e em cercar nosso objeto de estudo com o pensamento de alguns autores que contribuíssem com o andamento de nossas pesquisas, cônscios dos limites que algumas teorias nos imporiam se usadas em sua totalidade e sem questionamentos. Assim, no que se refere à questão dos sujets de fiction, os conceitos de moralidade, jogos e nonsense foram utilizados até a medida em que realmente podiam contribuir na caminhada aqui empreendida

Divided into three substantial chapters, this dissertation centres on the interconnections of madness and nonsense. In particular, the introduction analyzes theories on nonsense literature, and the binaric logics that separately structure the discursive fields of these two phenomena. In this section, there is also a deconstruction of the problematics of analyzing nonsense as a literary technique without the influence of mad studies. The first chapter then moves to take on the figure of the Western serial killer, and the hermeneutic projects that the media takes on when reporting on his “senseless” crimes. Arguing that the labelling of the serial killer’s crimes as “nonsensical” demonstrates a particular aesthetic that works to associate madness with danger, disease, fear, and hatred within the public imaginary, this dissertation offers an analysis through a reading of Lynn Crosbie’s Paul’s Case. In the final chapter, this dissertation employs Margaret Atwood’s Surfacing and Emma Donoghue’s The Wonder to consider nonsensical madness within the context of feminine subjectivity. Considering autotheory as a feminist hermeneutic practice then leads into the author’s own experiences as a mad person. This dissertation aims to consider how to engage with nonsensically mad feminine texts, and the ethics of the hermeneutics of mad reading-projects. / Dissertation / Doctor of Philosophy (PhD) / Why do we deem certain groups of people nonsensical? Why is nonsense considered the ‘mother-tongue’ of madness? This dissertation attempts to unfold some of the dimensions of these questions through an historical taxonomy of madness and nonsense as separate yet connected phenomena; an analysis of the media and popular categorization of the Western serial killer; and feminine people deemed ‘mad’ via hysteria. Using their own experiences of madness, the author asks how we can possibly read mad articulations when they are often chalked up to nonsense, as well as the sociopolitical implications of this configuration of nonsense and madness.

Thesis (Ph.D.)--McMaster University (Canada), 1995. / Source: Dissertation Abstracts International, Volume: 56-12, Section: B, page: 6729. Adviser: J. P. Capone.