Spelling suggestions: "subject:"medi"" "subject:"edi""
61 |
Caracteriza??o do perfil neuropsicol?gico, acad?mico e comportamental de crian?as e adolescentes sobreviventes de tumores de fossa posteriorCampelo, Danielle Ferreira Garcia Mafra 01 December 2016 (has links)
Submitted by Automa??o e Estat?stica (sst@bczm.ufrn.br) on 2017-04-17T20:58:04Z
No. of bitstreams: 1
DanielleFerreiraGarciaMafraCampelo_TESE.pdf: 12451781 bytes, checksum: 2d36de05d3f436e95789402636f289ad (MD5) / Approved for entry into archive by Arlan Eloi Leite Silva (eloihistoriador@yahoo.com.br) on 2017-04-18T18:19:09Z (GMT) No. of bitstreams: 1
DanielleFerreiraGarciaMafraCampelo_TESE.pdf: 12451781 bytes, checksum: 2d36de05d3f436e95789402636f289ad (MD5) / Made available in DSpace on 2017-04-18T18:19:09Z (GMT). No. of bitstreams: 1
DanielleFerreiraGarciaMafraCampelo_TESE.pdf: 12451781 bytes, checksum: 2d36de05d3f436e95789402636f289ad (MD5)
Previous issue date: 2016-12-01 / O c?ncer ? a primeira causa de morte de crian?as no Brasil, com 12.600 casos estimados para
2017. Tumores de sistema nervoso central (SNC) s?o os mais comuns na inf?ncia e 60%
atingem cerebelo e adjac?ncias na fossa posterior. A les?o e o tratamento impactam o SNC e
altera??es em fun??es complexas v?m sendo associadas ? interrup??o de conex?es entre o
cerebelo e ?reas corticais. A radioterapia, respons?vel pelo aumento da sobrevida em casos de
tumores malignos, possui a??o neurot?xica sobre o SNC em desenvolvimento. O objetivo do
presente estudo ? investigar o funcionamento neuropsicol?gico e acad?mico de crian?as e
adolescentes sobreviventes de tumores de fossa posterior. A pesquisa foi subdividida em tr?s
estudos: 1) Caracteriza??o da capacidade intelectual de pacientes pedi?tricos diagnosticados
com tumores de fossa posterior; 2) Investiga??o das fun??es executivas em pacientes
pedi?tricos sobreviventes de tumores de fossa posterior e; 3) Proposi??o de modelo conceitual
para explicar o perfil neuropsicol?gico de crian?as e adolescentes submetidas ? radia??o
craniana. 37 sujeitos com idades entre seis e 16 anos compuseram o grupo cl?nico e 24
sujeitos saud?veis compuseram grupo controle, pareados 1:1 segundo sexo, idade, tipo de
escola e n?vel socioecon?mico dos participantes dos estudos 2 e 3. Os participantes passaram
por avalia??o neuropsicol?gica, com resultados analisados por ferramentas estat?sticas
descritivas e inferenciais e an?lise cl?nico-qualitativa. No estudo 1, crian?as submetidas ?
radioterapia apresentaram desempenho significativamente inferior ao de crian?as submetidas
apenas ? neurocirurgia em todos os dom?nios intelectuais, notadamente os n?o-verbais e
velocidade de processamento. O dom?nio n?o verbal revelou diferen?as significativas em
fun??o do tipo de tratamento, enquanto o dom?nio verbal acarretou diferen?as significativas
em fun??o da escolaridade materna, revelando dissocia??o quanto aos dom?nios cognitivos
mais afetados pelo tumor e pelo tratamento, e aqueles mais impactados por fatores socioculturais. Crian?as diagnosticadas tardiamente apresentaram pior desempenho,
contradizendo estudos anteriores. O estudo 2 revelou altera??es executivas nos dom?nios da
mem?ria de trabalho, inibi??o, flexibilidade e planejamento em ambos os grupos cl?nicos.
Crian?as submetidas ? radioterapia apresentaram mais dom?nios afetados e preju?zos mais
severos. Crian?as tratadas apenas com neurocirurgia apresentaram dificuldades restritas a
tarefas com demandas executivas mais sofisticadas, enquanto crian?as submetidas ?
radioterapia apresentaram dificuldades nestes e em tarefas mais simples. O estudo 3
apresentou importantes resultados em dire??o ? compreens?o do perfil neuropsicol?gico de
crian?as submetidas ? radioterapia. Os dados sugerem que a desmieliniza??o provocada pela
radioterapia acarreta altera??es t?picas de les?es do hemisf?rio direito, em padr?o semelhante
ao perfil do Transtorno N?o-Verbal de Aprendizagem (TNVA). As reflex?es te?ricas
resultantes da interpreta??o dos dados levaram ? proposi??o de modelo conceitual,
compreensivo e sist?mico como hip?tese explicativa para a emerg?ncia do perfil
neuropsicol?gico apresentado por sobreviventes de meduloblastoma. Espera-se que o estudo
estimule o interesse pelo aprofundamento da compreens?o acerca das dificuldades e desafios
enfrentados por essa popula??o, visando contribuir para a proposi??o de pol?ticas p?blicas que
promovam a reinser??o social e acad?mica das crian?as ap?s o tratamento, bem como para a
cria??o de programas de interven??o que garantam a melhoria da qualidade de vida dos
sobreviventes. / Cancer is the leading cause of death among Brazilian children, and 12.600 cases are estimated
for 2017. Central nervous system (CNS) tumors are the most common on childhood, from
which 60% arise in cerebellum or adjacent structures of posterior fossa. The lesion and
treatment affect CNS functioning, and alterations in higher order functions have been related
to the interruption of important connections between the cerebellum and cortical areas.
Radiotherapy is responsible for increasing survivorship in malignant tumor cases, but it also
promotes neurotoxic effects to the developing CNS. This study aimed to investigate
neuropsychological and academic functioning in survivors of posterior fossa tumors. The
research was subdivided into three studies: 1) Description of intellectual performance of
pediatric patients diagnosed with posterior fossa tumors; 2) Investigation of executive
functions in pediatric survivors of posterior fossa tumors and; 3) Proposal of a conceptual
model to explain the neuropsychological profile of children and adolescents submitted to
cranial radiation. 37 subjects aged 6-16 integrated clinical group, and 24 subjects formed a
healthy control group matched 1:1 with the participants of studies 2 and 3 according to sex,
age, type of school and socioeconomic level. Participants were submitted to
neuropsychological evaluation and results were analyzed through descriptive and inferential
statistical tools and clinic-qualitative analysis. In the first study, children who underwent
radiotherapy had significantly lower performances on intellectual domains compared to
children only surgically treated, mainly in nonverbal and processing speed domains.
Nonverbal domain revealed significant differences according to treatment modality, while
verbal domain led to significant differences according to mother educational level, which
reveals a dissociation regarding to the domains more strongly affected by the tumor and the
treatment, and the domains more affected by sociocultural factors. Children diagnosed later showed lower performances, which disagree with previous studies. The second study revealed
executive impairments on both clinical groups in terms of working memory, inhibition,
flexibility and planning. Children submitted to radiotherapy showed a broader range of
affected domains and the most serious impairments compared to children who did not
undergo radiotherapy. These children showed difficulties only in measures with more
sophisticated executive demands, while children submitted to radiotherapy also presented
impairments in more simple executive tasks. The third study presented important results
towards the comprehension of the neuropsychological profile of children submitted to cranial
radiation therapy. Data suggest that demyelination caused by radiotherapy leads to right
hemisphere typical impairments, in a pattern which is similar to the Nonverbal Learning
Disability (NLD) profile. Theoretical reflections resulting from data interpretation led to the
proposition of a conceptual, comprehensive and systemic model as an explanation hypothesis
to the emergency of childhood medulloblastoma neuropsychological profile. It is expected
that this study encourage research interest towards the understanding of difficulties and
challenges faced by this population, in order to contribute to the creation of public policies
which enable children?s social and academic reinsertion after treatment, as well as to the
creation of intervention programs which ensure the improvement of survivors? quality of life.
|
62 |
Evaluation of mixtures of acacia karroo leaf meal and setaria verticillata grass hay for indigenous Pedi goat productionBrown, David Adekunle January 2016 (has links)
Thesis (Ph.D. (Animal Nutrition)) -- University of Limpopo, 2016 / Refer to document
|
63 |
The psychology of bereavement and mourning rituals in a Northern Sotho communityMakgahlela, Mpsanyana Wilson January 2016 (has links)
Thesis (Ph.D. ( Psychology)) -- University of Limpopo, 2016 / The Euro-American bereavement literature has greatly contributed towards the management of the bereaved over centuries by psychologists. However, much of the literature lacks inclusion of non-westerners‘ bereavement and grief experiences. In light of this historical weakness, the aim of the present study was to explore bereavement and mourning in the Northern Sotho community with a view to identifying and documenting the psychological themes embedded in this culturally constructed experience. A total of fourteen participants (male = 7; females = 7; aged between 35 and 85) were selected using the snowball sampling method. The data were collected using in-depth semi-structured interviews. Hycner‘s adapted phenomenological explicitation method was used to analyse the data.
The four major themes that emerged during data-explicitation were; a). The influence of belief systems on the conception of death; b). The experience and expression of the pain of grief; c). Diverse bereavement rituals and cultural practices that are performed to heal the bereaved, and; d). Various mechanisms that are put in place to quarantine the bereaved from spreading death contaminations. The study findings suggest that the conceptualisation, experience, and expression of bereavement is profoundly influenced by an interplay of a plethora of factors that include people‘s varying worldviews, cultural practices, and now, the emerging new-global culture. Based on the findings of the study, a culturally informed bereavement conceptual model was developed. The model proposes that a clinician should be guided by four domains when providing grief counselling. The first domain involves the clinician looking into the client‘s belief system and how this influences the client‘s grieving process. The second domain entails analysis of the nature and circumstances surrounding death. In the third domain, the clinician will need to examine the influence of various psychological, physical and socioeconomic factors on the client‘s grief. And lastly, the clinician will need to determine the intensity and duration of the grief experience. It is envisaged that this model could help in the provision of person-centred grief counselling services within a multicultural context. The study further elaborates on the lessons the field of psychology could learn from the study findings. The findings are also discussed in the context of the emerging field of Africa psychology. / SAHUDA/NIHSS
|
64 |
The social and ceremonial music of the PediHuskisson, Yvonne January 1958 (has links)
Thesis (Ph.D.)--University of the Witwatersrand, Faculty of Arts, School of Music,1958 / The tribes that fall under the Northern Sotho or Pedi language group
are found in the area more or less bounded by Middelburg, Pilgrims Rest,
Malopene, the Blaauwberg and Hamanskraal .
No print can adequately describe the vital panorama of Pedi life.
In surveying the musical practices of the Pedi I soon realised that their
music was not an isolated entity but an integral unit of their whole
pattern of living, both socially and ceremonially. It is from this
essentially ' alive' standpoint, rather than as a scientific analysis of
scale systems, etc., that I approached the subject of Pedi music. [Abbreviated Abstract. Open document to view full version] / WS2016
|
65 |
Strategies for holistic health support of men in polygynous relationshipsMakua, T. P. January 2014 (has links)
The study has two separate but related aims, which are to explore the social and health experiences of men who are in polygynous relationships and to develop holistic health and social strategies to support men who are in polygynous relationships.
Objectives of the study were to identify the different permutations of polygynous relationships that related to health and social issues; to clarify the social status of men who are in polygynous relationship; to explore and describe the health experiences of men in polygynous relationship; to explore and describe the social experiences of men in polygynous relationship; to explore the spiritual experiences of men who are in a polygynous relationship; to describe and to generate holistic strategies to support men who are in a polygynous relationships.
Method: In this study, the researcher used descriptive and interpretive phenomenological processes to develop a range of holistic strategies to support men who were in polygynous relationships. The researcher described the experiences and developed interpretations based on the lived experiences that the men reported.
Findings: Polygyny remains the reality within the Bapedi tribe in Sekhukhune area. The practice of polygyny is not only for the affluent as indicated in most literature but is also practiced as a corrective strategy for families who are experiencing marital problems. Polygyny is not viewed as abusive to the women and children but rather beneficial to the women. It helps to reduce the risks of the development of cervical cancer that is predisposed by frequency of sexual intercourse. Polygyny promotes the morals within the communities, as children grow up within the two parents’ environment as opposed to the rising numbers of single parent families. Polygyny practice in the Sekhukhune areas is a voluntary choice and not a forced marital arrangement.
Conclusions and recommendations: The researcher recommended policy guidance to support health practitioners with strategies to assist members of polygynous families in need of help. The policy also guides employers to recognise and to register the second or third wife as beneficiaries of the working husband. / Health Studies / D. Litt. et Phil . (Health Studies)
|
66 |
Strategies for holistic health support of men in polygynous relationshipsMakua, T. P. January 2014 (has links)
The study has two separate but related aims, which are to explore the social and health experiences of men who are in polygynous relationships and to develop holistic health and social strategies to support men who are in polygynous relationships.
Objectives of the study were to identify the different permutations of polygynous relationships that related to health and social issues; to clarify the social status of men who are in polygynous relationship; to explore and describe the health experiences of men in polygynous relationship; to explore and describe the social experiences of men in polygynous relationship; to explore the spiritual experiences of men who are in a polygynous relationship; to describe and to generate holistic strategies to support men who are in a polygynous relationships.
Method: In this study, the researcher used descriptive and interpretive phenomenological processes to develop a range of holistic strategies to support men who were in polygynous relationships. The researcher described the experiences and developed interpretations based on the lived experiences that the men reported.
Findings: Polygyny remains the reality within the Bapedi tribe in Sekhukhune area. The practice of polygyny is not only for the affluent as indicated in most literature but is also practiced as a corrective strategy for families who are experiencing marital problems. Polygyny is not viewed as abusive to the women and children but rather beneficial to the women. It helps to reduce the risks of the development of cervical cancer that is predisposed by frequency of sexual intercourse. Polygyny promotes the morals within the communities, as children grow up within the two parents’ environment as opposed to the rising numbers of single parent families. Polygyny practice in the Sekhukhune areas is a voluntary choice and not a forced marital arrangement.
Conclusions and recommendations: The researcher recommended policy guidance to support health practitioners with strategies to assist members of polygynous families in need of help. The policy also guides employers to recognise and to register the second or third wife as beneficiaries of the working husband. / Health Studies / D. Litt. et Phil. (Health Studies)
|
67 |
The melting pot in Ga-Matlala Maserumule with special reference to the Bapedi culture, language and dialectsMokwana, Mabule Lizzy 11 1900 (has links)
The dissertation tries to explain why most of the Bapedi people do not feel free to speak their language when they are among other communities. It explains why the speakers of the so-called ‘inferior’ dialects of the Limpopo Province have an inferiority complex while the speakers of the ‘superior’ dialects are confident when speaking their dialects.
The standardisation of the Northern Sotho Language Board and the missionary activities within the Bapedi communities led to the creation of 'superior' and ‘inferior’ dialects.
A detailed discussion is presented of the social rural and urban varieties, which found in Bapedi culture. Some of these varieties are kept secret and therefore are unknown to the public; and others, which are not secretive in nature.
The use of language and the impact of language contact between languages is discussed. / African Languages / M.A. (African Languages)
|
68 |
Die bepaling van die psigometriese eienskappe van die Gesinskoherensie-vraelys en die Gesinsfunksioneringsvraelys vir gebruik onder Noord-SothosBouwer, Andre 12 1900 (has links)
Thesis (MA)- University of Stellenbosch, 2004. / ENGLISH ABSTRACT: The aim of the present study was to investigate the psychometric properties of
the Family Sense of Coherence Questionnaire (FSoC) for use among Northern
Sothos. Antonovsky and Sourani developed the FSoC-questionnaire to measure
the sense of coherence of families. The family sense of coherence is based on
the individual sense of coherence construct, which was developed by
Antonovsky. According to Antonovsky, families with a strong sense of coherence
will function better than families with a weak sense of coherence. Therefore
family functioning was used as criteria to validate the external validity of the
FSoC-questionnaire.
Olson, Russell and Sprenkle developed the Family Attachment and
Changeability Index (FACI-8) to measure family functioning according to the
Circumplex model. For the purpose of this study the two questionnaires were
translated to Sepedi (the language of the Northern Sotho). The reliability of the
two questionnaires was assessed by means of Cronbach-alpha coefficients. The
construct validity of the two questionnaires was assessed by means of
JOreskog's Goodness of Fit Index (GFI). The statistical analysis was done with
Statistica 6 software.
The results drawn from the present study indicates that the FSoC-questionnaire
is not a reliable and valid instrument to measure families' sense of coherence
among Northern Sothos. Significant high correlations with the FACI-8 however,
indicated that the FSoC might be considered for use among Northern Sothos, if
only the total scores are taken into consideration.
The FACI-8 however, proved to be a reliable and valid instrument to measure
family functioning according to the Circumplex model among Northern Sothos.
The conclusions drawn from the present study are that the FACI-8 is a suitable
instrument for use among the Northern Sothos, whereas the FSoC-questionnaire
is not. / AFRIKAANSE OPSOMMING: Die doel van die huidige ondersoek was om die psigometriese eienskappe van
die Gesinskoherensie-vraelys (FSoC) wat deur Antonovsky en Sourani ontwikkel
was, vir gebruik onder Noord-Sothos te bepaal. Om hierdie doeleindes te bereik,
was die Gesinsfunksioneringsvraelys (FACI-8) wat deur McCubbin, Thompson
en Elver ontwikkel was, as 'n kriterium gebruik om die eksterne geldigheid van
die FSoC-vraelys te valideer. Die FACI-8 meet gesinsfunksionering volgens die
Kontekstuele-model van gesinsfunksionering, wat deur Olson, Russell en
Sprenkle ontwikkel was.
Volgens Antonovsky sal gesinne wat oor 'n sterk ontwikkelde koherensiesin
beskik, beter funksioneer as gesinne wat oor 'n swak ontwikkelde koherensiesin
beskik. Gevolglik was gesinsfunksionering as 'n maatstaf van gesinskoherensie
gebruik.
Die vraelyste moes eers na Sepedi (die taal van die Noorcl-Sotho) vertaal word,
alvorens die vraelyste afgeneem kon word. Die betroubaarheid van die vraelyste
was deur middel van Cronbach-alfa koêffisiênte bereken. Die konstrukgeldigheid
van die vraelyste was deur middel van JOreskog se Passingstoets bepaal. Die
statistiese verwerkings was deur middel van die Statistica 6 rekenaarprogram
behartig.
Die resultate van die huidige ondersoek dui daarop dat die FSoC-vraelys met
omsigtigheid benader moet word vir gebruik onder Noord-Sothos. Die FSoCvraelys
het nie bevredigende betroubaarheids- en geldigheidsindekse gelewer
nie. Die FSoC-vraelys het wel eksterne geldigheid getoon, wanneer dit met die
FACI-8 gevalideer was.
Die FACI-8 het betroubare en geldige metings van gesinsfunksionering volgens
die Kontekstuele-model onder Noord-Sothos in die huidige ondersoek gelewer.
Die gevolgtrekkings wat op grond van die huidige ondersoek gemaak word, is dat
die FSoC-vraelys nie bruikbaar is onder Noorcl-Sothos nie, terwyl die FACI-8 wel
gebruik kan word om gesinsfunksionering onder Noord-Sothos te meet.
|
69 |
The melting pot in Ga-Matlala Maserumule with special reference to the Bapedi culture, language and dialectsMokwana, Mabule Lizzy 11 1900 (has links)
The dissertation tries to explain why most of the Bapedi people do not feel free to speak their language when they are among other communities. It explains why the speakers of the so-called ‘inferior’ dialects of the Limpopo Province have an inferiority complex while the speakers of the ‘superior’ dialects are confident when speaking their dialects.
The standardisation of the Northern Sotho Language Board and the missionary activities within the Bapedi communities led to the creation of 'superior' and ‘inferior’ dialects.
A detailed discussion is presented of the social rural and urban varieties, which found in Bapedi culture. Some of these varieties are kept secret and therefore are unknown to the public; and others, which are not secretive in nature.
The use of language and the impact of language contact between languages is discussed. / African Languages / M.A. (African Languages)
|
70 |
Efeito da posi??o prona na diurese e balan?o h?drico de pacientes pedi?tricos submetidos a ventila??o mec?nicaDall'Agnese, Rosirene Maria Fr?hlich 31 October 2017 (has links)
Submitted by PPG Pediatria e Sa?de da Crian?a (pediatria-pg@pucrs.br) on 2018-05-21T13:44:05Z
No. of bitstreams: 1
Disserta??o Rosirene DallAgnese p?s-banca.pdf: 1579820 bytes, checksum: 8b18b2dd28fd5e5160df51c8f463aef9 (MD5) / Approved for entry into archive by Caroline Xavier (caroline.xavier@pucrs.br) on 2018-06-06T17:55:06Z (GMT) No. of bitstreams: 1
Disserta??o Rosirene DallAgnese p?s-banca.pdf: 1579820 bytes, checksum: 8b18b2dd28fd5e5160df51c8f463aef9 (MD5) / Made available in DSpace on 2018-06-06T17:58:54Z (GMT). No. of bitstreams: 1
Disserta??o Rosirene DallAgnese p?s-banca.pdf: 1579820 bytes, checksum: 8b18b2dd28fd5e5160df51c8f463aef9 (MD5)
Previous issue date: 2017-10-31 / Coordena??o de Aperfei?oamento de Pessoal de N?vel Superior - CAPES / Introduction: Respiratory diseases in pediatrics are important causes of hospitalization in the Pediatric Intensive Care Unit (PICU) and, not withstanding, to the need for mechanical ventilation. The use of mechanical ventilation and continuous sedation associated with the administration of fluids, which severe patients need for initial hemodynamic stabilization, often result in a cumulative positive fluid balance. This hydric overload is associated with worse outcomes. Among the alternatives for the hydric balance to be optimized, the establishment of the prone position is found as such. Objectives: To verify if the prone position in pediatric patients submitted to mechanical ventilation increases diuresis with optimization in the hydric balance as well as to verify if this improvement has repercussions in days of mechanical ventilation and hospitalization in PICUs. Methods: Retrospective cohort through review of medical records. It was selected patients who were submitted to ventilation for pulmonary causes and aged from 1 month old to 12 years old. The prone group (PG) was the one in which the patients were submitted to the prone position at some point of the study. The control group (CG) was the one in which the patients met the inclusion criteria but were not undergone prone position. The collected data included demographic data, Pediatric Index of Mortality (PIM 2), hydric balance, diuresis, use of diuretics and vasoactive drug index, mechanical ventilation duration, prone position duration, relationship between prone and mechanical ventilation duration, besides duration of hospital stay (PICU and hospital). Mann-Whitney and Chi-Square tests were used to compare the PG and CG groups. For the longitudinal analysis, repeated measures of ANOVA were used, using BH (ml/kg/day), diuresis (ml/kg/h) and the amount of furosemide (mg/kg/day) during a period classified as D1 to D4 (D1 being the first day of mechanical ventilation in the CG and the day immediately before prone in the PG). The main outcome was the increase of diuresis and the improvement of hydric balance in pronated patients. The secondary outcome was the decrease of duration of mechanical ventilation and hospitalization in the PICU and in the hospital. Results: 84 patients were included and, after some losses, 77 (PG=37 and CG=40) remained. Regarding age, sex, pathologies, index of mortality, death, use of vasoactive drugs and occurrence of intercurrences, the groups were similar. There was no significant improvement of diuresis, hydric balance, mechanical ventilation and hospitalization duration in the PICU. Regarding the use of diuretics, there was greater use of furosemide (P<0.001) and spironolactone (P=0.04) in the PG. When performed a longitudinal analysis of repeated measures of D1 to D4, it was shown that both PG and CG had improved diuresis and hydric balance, with a more significant improvement from D1 to D2 in the PG (P=0.034). However, when verifying this improvement, it was noticed that it was also related to the use of diuretics. Conclusion: Throughout the analysed days of mechanical ventilation (D1 to D4), there was improvement of both diuresis and hydric balance of patients in both groups, without showing, however, superiority of the prone group in relation to the control group. / Introdu??o: Doen?as respirat?rias em pediatria s?o importantes causas de interna??o em Unidade de Terapia Intensiva Pedi?trica (UTIP) e, n?o raro, levam a necessidade de ventila??o mec?nica. O uso de ventila??o mec?nica e de seda??o cont?nua associados ? administra??o de fluidos que o paciente grave necessita para a sua estabiliza??o hemodin?mica inicial, frequentemente ocasionam balan?o h?drico positivo cumulativo. Essa sobrecarga h?drica est? associada a piores desfechos. Entre as alternativas para que o balan?o h?drico seja otimizado, encontra-se, entre outras, a instaura??o da posi??o prona. Objetivos: Verificar se a posi??o prona em pacientes pedi?tricos submetidos a ventila??o mec?nica aumenta a diurese com otimiza??o no balan?o h?drico, bem como aferir se essa melhora repercute em dias de ventila??o mec?nica e de interna??o em UTIP. M?todos: coorte retrospectiva atrav?s de revis?o de prontu?rios. Foram selecionados os pacientes, submetidos a ventila??o por causa pulmonar, com idade entre 1 m?s e 12 anos. O grupo prona (GP) foi aquele em que os pacientes foram submetidos a posi??o prona em algum momento do estudo. O grupo controle (GC) foi aquele em que os pacientes preencheram os crit?rios de inclus?o, mas que n?o foram submetidos a posi??o prona. Os dados coletados inclu?ram dados demogr?ficos, escore de mortalidade (PIM 2), balan?o h?drico, diurese, uso de diur?ticos e ?ndice de drogas vasoativas, tempo de ventila??o mec?nica, tempo de posi??o prona, rela??o entre o tempo de prona e ventila??o mec?nica, al?m do tempo de interna??o (UTIP e no hospital). Para a compara??o entre os grupos GP e GC foram utilizados os testes de Mann-Whitney e do Qui-Quadrado. Para a an?lise longitudinal optou-se por ANOVA de medidas repetidas, utilizando o BH (ml/kg/dia), a diurese (ml/kg/h) e a quantidade de furosemida(mg/kg/dia) durante um per?odo classificado de D1 a D4 (sendo D1 o primeiro dia de ventila??o mec?nica no GC e o dia imediatamente anterior ? prona no GP). O desfecho principal foi o aumento da diurese e melhora do balan?o h?drico nos pacientes pronados. O desfecho secund?rio foi a diminui??o no tempo de ventila??o mec?nica e de interna??o em UTIP e no hospital. Resultados: foram inclu?dos 84 pacientes e, ap?s as perdas, permaneceram 77 (GP=37 e GC= 40). Em termos de idade, sexo, patologias, escores de mortalidade, ?bito, uso de drogas vasoativas e ocorr?ncia de intercorr?ncias os grupos foram semelhantes. Atrav?s de compara??o entre os grupos n?o houve melhora significativa na diurese, balan?o h?drico, tempo de ventila??o mec?nica e de interna??o em UTIP. Com rela??o ao uso de diur?ticos, houve maior uso de furosemida (P<0,001) e de espironolactona (P=0,04) no GP. Quando realizada an?lise longitudinal de medidas repetidas de D1 a D4, evidenciou-se que tanto o GP quanto o GC tiveram melhora da diurese e do balan?o h?drico, com melhora mais significativa de D1 para D2 no GP (P=0,034). No entanto, ao se verificar essa melhora, percebeu-se que ela tamb?m estava relacionada ao uso de diur?ticos. Conclus?o: Ao longo dos dias de ventila??o mec?nica estudados (D1 a D4), houve melhora tanto na diurese quanto no balan?o h?drico dos pacientes de ambos os grupos, sem evidenciar-se, no entanto, superioridade do grupo prona em rela??o ao controle.
|
Page generated in 0.1924 seconds