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The Global ETD Search service is a free service for researchers
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Showing 1 to 7 of 7 (0.043 seconds)Spelling suggestions: "subject:"beptide amphiphile"" "subject:"beptide amphiphiles""
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DIFFERENTIATION OF NEURAL STEM CELL USING SMALL MOLECULES IN 2D AND 3D CULTURE SYSTEMShi, Xinglong January 2015 (has links)
The neuronal differentiation of neural stem cells (NSCs) has received much attention due to its potential for the treatment of neurodegenerative diseases (i.e., Parkinson’s and Alzheimer’s diseases). In this regard, discovering compounds that direct differentiation of NSCs is highly required to facilitate therapeutic applications. In this study, we examined various bioactive compounds (SA1, SA2, LiCl, compound B, and DHED) to induce the neuronal differentiation of human neural stem cells (hNSCs). The study was conducted on the cells grown in three dimensional (3D) hydrogel or two dimensional (2D) environment since 3D hydrogel mimics the extracellular matrix and provides physiologically more relevant environment than 2D cell culture system. Three-dimensional (3D) hydrogel systems in this study involve polysaccharides such as alginate and hyaluronic acid. Neuronal differentiation of hNSCs was monitored in genetic level and protein level by quantitative reverse transcription polymerase chain reaction (RT-qPCR) and immunocytochemistry (ICC), respectively. This study will show the effect of bioactive compounds on hNSCs differentiation in 2D and 3D culture systems. / Bioengineering
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Autoassemblage de peptides amphiphiles et de polymères pour l'élaboration de nouvelles membranes / Self-assembly of amphiphilic peptides and polymers for the development of new membranesBabut, Thomas 21 January 2019 (has links)
Le but de ce projet est de synthétiser des peptides amphiphiles ayant une partie structurante en feuillet beta afin d'obtenir des micelles cylindriques. La partie hydrophile du peptide est associée à un polymère qui va être le support de la membrane car le peptide seul ne se structure qu'en micelle cylindrique. Une fois la membrane créée, le peptide peut être enlevé ou alors laissé au sein de la membrane et cette membrane a des applications dans la filtration spécifique car elle est nanostructurée. / The goal of this project is to synthesize amphphilic peptides with a structuring part in beta sheet in order to obtain cylindrical mycelles. The hydrophylic part of the peptide is associated to a polymer which will be the support of the membrane because the peptide itself doesn't associate to crate a membrane. With the membrane, we can remove the peptide or not and this membrane has specific filtration properties since it is nanostructured.
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Development of pH-triggered, Self-assembling Peptide Amphiphiles as Tumor Targeting Imaging Vehicles.Ghosh, Arijit 17 October 2014 (has links)
No description available.
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Design and Biological Characterization of Peptide Amphiphile Nanoparticles for Targeted Tumor DeliveryBuettner, Christian J. 25 August 2017 (has links)
No description available.
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Self-Assembling Peptide Amphiphile Contrast Agents as a Tumor Diagnostic ToolHaverick, Mark Anthony 20 October 2011 (has links)
No description available.
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Peptide and Protein Supramolecular Assemblies Studied by Solid-State NMR SpectroscopyQi, Zhe 07 September 2017 (has links)
No description available.
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Développement de systèmes polymère-(poly)peptide en vue de l'immobilisation de vésicules lipidiquesPercot, Aline January 2000 (has links)
Thèse numérisée par la Direction des bibliothèques de l'Université de Montréal.
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