With recent advances in data-as-a-service (DaaS) and cloud computing, outsourcing data to the cloud has become a common practice. In a typical scenario, the data owner (DO) outsources the data and delegates the query processing service to a service provider (SP). However, as the SP is often an untrusted third party, the integrity of the query results cannot be guaranteed and is thus imperative to be authenticated. To tackle this issue, a typical approach is letting the SP provide a cryptographic proof, which can be used to verify the soundness and completeness of the query results by the clients. Despite extensive research on authenticated query processing for outsourced databases, existing techniques have only considered limited query types. They fail to address a variety of needs demanded by enterprise customers such as supporting aggregate queries over set-valued data, enforcing fine-grained access control, and using distributed computing paradigms. In this dissertation, we take the first step to comprehensively investigate the authenticated query processing in the cloud that fulfills the aforementioned requirements. Security analysis and performance evaluation show that the proposed solutions and techniques are robust and efficient under a wide range of system settings.

Location based services (LBS) are gaining widespread user acceptance and increased daily usage. GPS based mobile navigation systems (Garmin), location-related social network updates and "check-ins" (Facebook), location-based games (Nokia), friend queries (Foursquare) and ads (Google) are some of the popular LBSs available to mobile users today. Despite these successes, current user services fall short of a vision where mobile users could ask for continuous location-based services with always-up-to-date information around them, such as the list of friends or favorite restaurants within 15 minutes of driving. Providing such a location based service in real time faces a number of technical challenges. In this dissertation research, we propose a suite of novel techniques and system architectures to address some known technical challenges of continuous location queries and updates. Our solution approaches enable the creation of new, practical and scalable location based services with better energy efficiency on mobile clients and higher throughput at the location servers. Our first contribution is the development of RoadTrack, a road network aware and query-aware location update framework and a suite of algorithms. A unique characteristic of RoadTrack is the innovative design of encounter points and system-defined precincts to manage the desired spatial resolution of location updates for different mobile clients while reducing the complexity and energy consumption of location update strategies. The second novelty of this dissertation research is the technical development of Dandelion data structures and algorithms that can deliver superior performance for the periodic re-evaluation of continuous road-network distance based location queries, when compared with the alternative of repeatedly performing a network expansion along a mobile user's trajectory. The third contribution of this dissertation research is the FastExpand algorithm that can speed up the computation of single-issue shortest-distance road network queries. Finally, we have developed the open source GT MobiSim mobility simulator, a discrete event simulation platform to generate realistic driving trajectories for real road maps. It has been downloaded and utilized by many to evaluate the efficiency and effectiveness of the location query and location update algorithms, including the research efforts in this dissertation.

In recent years the amount of information on the web has increased dramatically. As a result, it has become a challenge for the researchers to find effective ways that can help us query and extract meaning from these large repositories. Standard document search engines try to address the problem by presenting the users a ranked list of relevant documents. In most cases, this is not enough as the end-user has to go through the entire document to find out the answer he is looking for. Question answering, which is the retrieving of answers to natural language questions from a document collection, tries to remove the onus on the end-user by providing direct access to relevant information. This thesis is concerned with open-domain complex question answering. Unlike simple questions, complex questions cannot be answered easily as they often require inferencing and synthesizing information from multiple documents. Hence, we considered the task of complex question answering as query-focused multi-document summarization. In this thesis, to improve complex question answering we experimented with both empirical and machine learning approaches. We extracted several features of different types (i.e. lexical, lexical semantic, syntactic and semantic) for each of the sentences in the document collection in order to measure its relevancy to the user query. We have formulated the task of complex question answering using reinforcement framework, which to our best knowledge has not been applied for this task before and has the potential to improve itself by fine-tuning the feature weights from user feedback. We have also used unsupervised machine learning techniques (random walk, manifold ranking) and augmented semantic and syntactic information to improve them. Finally we experimented with question decomposition where instead of trying to find the answer of the complex question directly, we decomposed the complex question into a set of simple questions and synthesized the answers to get our final result. / x, 128 leaves : ill. ; 29 cm

A k nearest neighbor query q retrieves k objects that lie closest to the query point q among a given set of objects P. With the availability of inexpensive location aware mobile devices, the continuous monitoring of such queries has gained lot of attention and many methods have been proposed for continuously monitoring the kNNs in highly dynamic environment. Multiple continuous queries require real-time results and both the objects and queries issue frequent location updates. Most popular spatial index, R-tree, is not suitable for continuous monitoring of these queries due to its inefficiency in handling frequent updates. Recently, the interest of database community has been shifting towards using grid-based index for continuous queries due to its simplicity and efficient update handling. For kNN queries, the order in which cells of the grid are accessed is very important. In this research, we present two efficient and effective grid access methods, CircularTrip and ArcTrip, that ensure that the number of cells visited for any continuous kNN query is minimum. Our extensive experimental study demonstrates that CircularTrip-based continuous kNN algorithm outperforms existing approaches in terms of both efficiency and space requirement. Moreover, we show that CircularTrip and ArcTrip can be used for many other variants of nearest neighbor queries like constrained nearest neighbor queries, farthest neighbor queries and (k + m)-NN queries. All the algorithms presented for these queries preserve the properties that they visit minimum number of cells for each query and the space requirement is low. Our proposed techniques are flexible and efficient and can be used to answer any query that is hybrid of above mentioned queries. For example, our algorithms can easily be used to efficiently monitor a (k + m) farthest neighbor query in a constrained region with the flexibility that the spatial conditions that constrain the region can be changed by the user at any time.

A k nearest neighbor query q retrieves k objects that lie closest to the query point q among a given set of objects P. With the availability of inexpensive location aware mobile devices, the continuous monitoring of such queries has gained lot of attention and many methods have been proposed for continuously monitoring the kNNs in highly dynamic environment. Multiple continuous queries require real-time results and both the objects and queries issue frequent location updates. Most popular spatial index, R-tree, is not suitable for continuous monitoring of these queries due to its inefficiency in handling frequent updates. Recently, the interest of database community has been shifting towards using grid-based index for continuous queries due to its simplicity and efficient update handling. For kNN queries, the order in which cells of the grid are accessed is very important. In this research, we present two efficient and effective grid access methods, CircularTrip and ArcTrip, that ensure that the number of cells visited for any continuous kNN query is minimum. Our extensive experimental study demonstrates that CircularTrip-based continuous kNN algorithm outperforms existing approaches in terms of both efficiency and space requirement. Moreover, we show that CircularTrip and ArcTrip can be used for many other variants of nearest neighbor queries like constrained nearest neighbor queries, farthest neighbor queries and (k + m)-NN queries. All the algorithms presented for these queries preserve the properties that they visit minimum number of cells for each query and the space requirement is low. Our proposed techniques are flexible and efficient and can be used to answer any query that is hybrid of above mentioned queries. For example, our algorithms can easily be used to efficiently monitor a (k + m) farthest neighbor query in a constrained region with the flexibility that the spatial conditions that constrain the region can be changed by the user at any time.

Indiana University-Purdue University Indianapolis (IUPUI) / Pharmacodynamics (PD) studies the relationship between drug concentration and drug effect on target sites. This field has recently gained attention as studies involving PD Drug-Drug interactions (DDI) assure discovery of multi-targeted drug agents and novel efficacious drug combinations. A PD drug combination could be synergistic, additive or antagonistic depending upon the summed effect of the drug combination at a target site. The PD literature has grown immensely and most of its knowledge is dispersed across different scientific journals, thus the manual identification of PD DDI is a challenge. In order to support an automated means to extract PD DDI, we propose Pharmacodynamics Miner (PD-Miner). PD-Miner is a text-mining tool, which is capable of identifying PD DDI from in vitro PD experiments. It is powered by two major features, i.e., collection of full text articles and in vitro PD ontology. The in vitro PD ontology currently has four classes and more than hundred subclasses; based on these classes and subclasses the full text corpus is annotated. The annotated full text corpus forms a database of articles, which can be queried based upon drug keywords and ontology subclasses. Since the ontology covers term and concept meanings, the system is capable of formulating semantic queries. PD-Miner extracts in vitro PD DDI based upon references to cell lines and cell phenotypes. The results are in the form of fragments of sentences in which important concepts are visually highlighted. To determine the accuracy of the system, we used a gold standard of 5 expert curated articles. PD-Miner identified DDI with a recall of 75% and a precision of 46.55%. Along with the development of PD Miner, we also report development of a semantically annotated in vitro PD corpus. This corpus includes term and sentence level annotations and serves as a gold standard for future text mining.