Global ETD Search

1	Poor Glycemic Control is Associated with Neuroretinal Dysfunction in Short-wavelength Cone Pathways of Adolescents with Type 1 Diabetes McFarlane, Michelle 12 January 2011 (has links) Studies demonstrate short-wavelength cone pathway dysfunction in patients with diabetes and no clinically visible DR. Poor glycemic control, as measured by hemoglobin A1c (HbA1c), is a strong risk factor for DR. We hypothesized that raised HbA1c was associated with short-wavelength cone sensitive visual evoked potential (S-VEP) and electroretinogram (sERG) dysfunction. Forty adolescents with diabetes and 39 controls were tested using the S-VEP. Latencies to a short-wavelength stimulus were delayed in patients at low contrasts. Patient S-VEP latencies were not associated with HbA1c when controlling for age and time since diagnosis. Twenty-one adolescents with diabetes and 19 controls were tested using the sERG. Implicit times of the b-wave were delayed but not associated with HbA1c when controlling for time since diagnosis.Patient PhNR amplitudes were reduced. A one-unit increase in HbA1c was associated with a 15% sERG PhNR amplitude reduction (p=0.004). The sERG PhNR may be a potential biomarker for DR. type 1 diabetes adolescents diabetic retinopathy short-wavelength S-cone visual evoked potential electroretinogram photopic negative response hemoglobin A1c glycemic control 0381
2	Poor Glycemic Control is Associated with Neuroretinal Dysfunction in Short-wavelength Cone Pathways of Adolescents with Type 1 Diabetes McFarlane, Michelle 12 January 2011 (has links) Studies demonstrate short-wavelength cone pathway dysfunction in patients with diabetes and no clinically visible DR. Poor glycemic control, as measured by hemoglobin A1c (HbA1c), is a strong risk factor for DR. We hypothesized that raised HbA1c was associated with short-wavelength cone sensitive visual evoked potential (S-VEP) and electroretinogram (sERG) dysfunction. Forty adolescents with diabetes and 39 controls were tested using the S-VEP. Latencies to a short-wavelength stimulus were delayed in patients at low contrasts. Patient S-VEP latencies were not associated with HbA1c when controlling for age and time since diagnosis. Twenty-one adolescents with diabetes and 19 controls were tested using the sERG. Implicit times of the b-wave were delayed but not associated with HbA1c when controlling for time since diagnosis.Patient PhNR amplitudes were reduced. A one-unit increase in HbA1c was associated with a 15% sERG PhNR amplitude reduction (p=0.004). The sERG PhNR may be a potential biomarker for DR. type 1 diabetes adolescents diabetic retinopathy short-wavelength S-cone visual evoked potential electroretinogram photopic negative response hemoglobin A1c glycemic control 0381
3	Genetic Signatures of the Retina in Health and Disease Mustafi, Debarshi 23 August 2013 (has links) No description available. Pharmacology Genetics Biogeochemistry Cellular Biology Health Sciences Medicine Retina Vision Photoreceptor LincRNA RNA-Seq Non-coding Enhanced S-cone syndrome Complex diseases Systems biology Genetics Inflammation
4	On completeness of partial metric spaces, symmetric spaces and some fixed point results 10 1900 (has links) The purpose of the thesis is to study completeness of abstract spaces. In particular, we study completeness in partial metric spaces, partial metric type spaces, dislocated metric spaces, dislocated metric type spaces and symmetric spaces that are generalizations of metric spaces. It is well known that complete metric spaces have a wide range of applications. For instance, the classical Banach contraction principle is phrased in the context of complete metric spaces. Analogously, the Banach's xed point theorem and xed point results for Lipschitzian maps are discussed in this context, namely in, partial metric spaces and metric type spaces. Finally, xed point results are presented for symmetric spaces / Mathematical Sciences / Ph. D. (Mathematics) Metric space Quasi metric space Dislocated metric space Partial metric space TV S-cone metric space TV S-partial cone metric space Dislocated cone metric space Convergent sequence Cauchy sequence Convergence complete Cauchy complete 0-Cauchy complete Contraction constant Contraction map Lipschitzian constant Lipschitzian map Fixed point Metric type space Dislocated metric type space Partial metric type space Symmetric space 516.1 Metric spaces Symmetric spaces
5	On completeness of partial metric spaces, symmetric spaces and some fixed point results Aphane, Maggie 12 1900 (has links) The purpose of the thesis is to study completeness of abstract spaces. In particular, we study completeness in partial metric spaces, partial metric type spaces, dislocated metric spaces, dislocated metric type spaces and symmetric spaces that are generalizations of metric spaces. It is well known that complete metric spaces have a wide range of applications. For instance, the classical Banach contraction principle is phrased in the context of complete metric spaces. Analogously, the Banach's xed point theorem and xed point results for Lipschitzian maps are discussed in this context, namely in, partial metric spaces and metric type spaces. Finally, xed point results are presented for symmetric spaces. / Geography / Ph. D. (Mathematics) Metric space Quasi metric space Dislocated metric space Partial metric space TV S-cone metric space TV S-partial cone metric space dislocated cone metric space Convergent sequence Cauchy sequence 0-Cauchy sequence Convergence complete Cauchy complete 0-Cauchy complete Contraction constant Contraction map Lipschitzian constant Lipschitzian map Fixed point Metric type space Dislocated metric type space Partial metric type space Symmetric space 514.325 Metric spaces Symmetric spaces Fixed point theory

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