Объектами исследования являются проволочная заготовка из пластичного металла, а также способ накопления пластической деформации в операции навивания. Цель работы - разработка и изучения нового способа накопления пластической деформации методом спирального изгиба проволочной заготовки из технически чистого серебра. Приведено теоретическое описание процесса спирального изгиба. Проведена работа по определению механических свойств обрабатываемого материала (в данном случае серебро марки Ср 99,99). Описаны результаты физического моделирования процесса накопления деформации новым способом. Приведена краткая характеристика комплекса математического моделирования процессов обработки металлов давлением QForm VX. В пакете моделирования QForm VX была решена задача накопления пластической деформации с помощью спирального изгиба проволочной заготовки с последующим распрямлением спирали, приведены и проанализированы результаты расчетов. / The objects of research are a wire billet made of ductile metal, as well as a method of accumulating plastic deformation in the winding operation. The purpose of this work is to develop and study a new method of accumulating plastic deformation by spiral bending of a wire blank made of commercially pure silver. A theoretical description of the spiral bending process is given. Work has been carried out to determine the mechanical properties of the processed material (in this case, silver of the Sr 99.99 brand). The results of physical modeling of the deformation accumulation process by a new method are described. A brief description of the QForm VX complex for mathematical modeling of metal forming processes is given. In the QForm VX modeling package, the problem of plastic deformation accumulation by spiral bending of a wire blank with subsequent straightening of the spiral was solved, and the calculation results are presented and analyzed.

В данной работе были рассмотрены различные испытательные машины, изучен принцип и особенности работы разрывной машины для статических испытаний металлов Р-10. Проведены расчеты геометрических параметров гидроцилиндров (основного рабочего и захватов), прочностной и расчет на устойчивость. Также, исходя из перечисленных расчетов подобран рабочий насос и среда – масло. Смоделированы детали модели в пакете программ SolidWorks, а в пакете MATLAB Simscape составлена сборка разрывной машины и добавлена система с гидроприводом. В результате исследования была получена имитационная модель статической разрывной машины для металлов, при помощи которой было проведено моделирование испытания на растяжение. Для этого был выбран образец стали известной марки с заранее определенными геометрическими параметрами. После чего к образцу были приложены различные усилия, и сняты показания удлинения образца. На основе этого был получен график. Затем с помощью данных усилие/перемещение и начальных геометрических параметров были рассчитаны пределы пропорциональности, текучести, прочности на основании которых и был определен материал образца. Данный пример демонстрирует правильность разработки подобных моделей в системе MATLAB, которые могут позволить провести детальные исследования процессов работы механизмов машины во время испытаний, в том числе оценить характеристики гидравлической системы разрывной испытательной машины. / In this dissertation, various testing machines were considered, the principle and features of the operation of a tensile testing machine for static testing of metals R-10 were studied. Calculations of the geometrical parameters of hydraulic cylinders (main working and grippers), strength and stability calculations were carried out. Also, based on the above calculations, a working pump and a medium - oil were selected. The details of the model were modeled in SolidWorks, and the tensile testing machine assembly was assembled in MATLAB Simscape and the hydraulic actuator system was added. As a result of the study, a simulation model of a static tensile testing machine for metals was obtained, with the help of which a simulation of a tensile test was carried out. For this, a sample of well-known brand steel with predetermined geometric parameters was selected. After that, various forces were applied to the sample, and indications of the elongation of the sample were taken. Based on this, a graph was obtained. Then, using the force / displacement data and the initial geometric parameters, the limits of proportionality, yield, strength were calculated, on the basis of which the sample material was determined. This example demonstrates the correctness of developing such models in MATLAB. They can make it possible to conduct detailed studies of the operation of the machine mechanisms during testing, including the evaluation of the characteristics of the hydraulic system of the tensile testing machine.

Water-assisted crack growth at an epoxy/glass interface was measured as a function of applied strain energy release rate, G, and temperature using a wedge test geometry. The specimens consist of two glass plates bonded with a thin layer of proprietary epoxy adhesive. The crack fronts along the epoxy/glass interfaces were measured using an optical stereomicroscope. The relationship between G and the debonding rate, v, can be measured using this method, and the threshold value of strain energy release rate, Gth, can be determined from the measured data. Two types of testing procedures were conducted in this study: ex situ, i.e., pre-conditioned wedge tests and in situ ones, in which wedges were applied before the specimens were submerged into water. A preliminary model was developed based on the thermal activation barrier concept, and allows the prediction of Gth for the temperatures beyond the testing region. Changes in interfacial strain energy release rate caused by thermal residual stresses in a triple-layered specimen were analyzed in Chapter Three. The method is based on linear elastic fracture mechanics and simple beam theory. The curvature of a bimaterial strip was chosen to characterize the residual stress in the specimen, and the strain energy release rate, caused by both tensile and compressive residual stresses in the adhesive, was derived for an asymmetric double cantilever beam (ADCB) geometry. The contribution of the thermal residual and mechanical stress to the global energy release rate was analyzed. The thermally induced energy release rate, GT, is found to be independent of crack length, but is a function of residual stress level and geometric and material parameters of the specimen. The adhesion of films and coatings to rigid substrates is often measured using blister geometries, which are loaded either by an applied pressure or a central shaft. The measurement will be affected if there are residual stresses that make a contribution to the energy release rate. This effect is investigated using analytical solutions based on the principle of virtual displacements. A geometrically nonlinear finite element analysis is conducted for comparison. Furthermore, the relationships among strain energy release rate, load, deflection, and fracture radius are discussed in detail in Chapter Four. Both analytical solutions and numerical results reveal that uniform tensile residual stresses reduce a specimen's deflection if it experiences plate behavior under small loads. However, this effect diminishes when membrane behavior is dominant. The mechanics of a single-lap joint with different boundary conditions subjected to tensile loading are investigated. Closed-form solutions are obtained for a specimen configuration considering different clamping methods. Based on the approach pioneered by Goland and Reissner, the solutions reported in this paper provide a simple but useful way to understand the effects of boundary conditions on this test geometry. The solutions in this study suggest that different grip configurations mainly affect the response of the specimens if the grip position is close to the joint edge or the loads are small. Generally, the influence caused by different gripping methods is only limited to the boundary region, and the behavior of the joint part subjected to tensile loading is almost the same as that for a simply-supported case. / Ph. D.

La coexistence de deux formats : cinéma à 24 images/s et vidéo à<br />25 images/s, implique l'accélération ou le ralentissement de la<br />bande-son lors du transfert d'un format vers l'autre. Ceci<br />provoque une modification temporelle du signal sonore, et par<br />conséquent une modification spectrale avec altération du timbre.<br />Les studios de post-production audiovisuelle souhaitent compenser<br />cet effet par l'application d'une transformation sonore adéquate.<br /><br />L'objectif de ce travail est de fournir à l'industrie<br />audiovisuelle un système permettant de pallier la modification de<br />timbre engendrée par le changement de vitesse de lecture. Ce<br />système se compose d'une part d'un algorithme de traitement et<br />d'autre part d'une machine sur lequel il est implanté.<br />L'algorithme est conçu et développé pour répondre aux contraintes<br />liées à la qualité sonore et à la compatibilité multicanal. La<br />machine, baptisée HARMO, est conçue spécifiquement par la société<br />GENESIS sur la base de processeurs de signaux numériques, et doit<br />répondre à la contrainte de temps-réel. Cet aspect "valorisation"<br />conduit à intégrer dans le projet les contraintes de coût et de<br />délai de réalisation.<br /><br />Un état de l'art basé sur une bibliographie quasi-exhaustive<br />aboutit à une classification originale des méthodes de dilatation<br />et de transposition existantes. Ceci nous amène à distinguer et à<br />étudier les méthodes classiques temporelles et fréquentielles, et<br />à introduire les méthodes temps-fréquence. Cette classification<br />est à la base de plusieurs méthodes innovantes :<br /><br />1. deux méthodes temps-fréquence dont l'analyse est adaptée à l'audition,<br /><br />2. deux méthodes couplées qui associent les avantages des méthodes temporelles et fréquentielles,<br /><br />3. une méthode temporelle basée sur une amélioration des méthodes existantes.<br /><br />Les algorithmes sont évalués grâce à une banque de sons-test<br />spécifiquement élaborée pour mettre en évidence les défauts<br />caractéristiques des algorithmes. Notre choix final s'est porté<br />sur l'approche temporelle, que nous optimisons par l'adjonction de<br />critères de segmentation basés sur l'autocorrélation normalisée et<br />la détection de transitoires. Cet algorithme s'intègre dans un<br />logiciel qui a été structuré pour un fonctionnement temps-réel et<br />multicanal sur le système HARMO.

Calcific aortic valve disease (CAVD) is one of the most common causes of cardiovascular disease in North America. Mechanical factors have been closely linked to the pathogenesis of CAVD and may contribute to the disease by actively regulating the mechanobiology of valve interstitial cells (VICs). Mechanical forces affect VIC function through interactions between the VIC and the extracellular matrix (ECM). Studies have shown that the transfer of mechanical stimulus during cell-ECM interaction depends on the local material properties at hierarchical length scales encompassing tissue, cell and cytoskeleton. In this thesis, biomechanical tools were developed and applied to investigate hierarchical cell-ECM interactions, using VICs and valve tissue as a model system. Four topics of critical importance to understanding VIC-ECM interactions were studied: focal biomechanical material properties of aortic valve tissue; viscoelastic properties of VICs; transduction of mechanical deformation from the ECM to the cytoskeletal network; and the impact of altered cell-ECM interactions on VIC survival. To measure focal valve tissue properties, a micropipette aspiration (MA) method was implemented and validated. It was found that nonlinear elastic properties of the top layer of a multilayered biomaterial can be estimated by MA by using a pipette with a diameter smaller than the top layer thickness. Using this approach, it was shown that the effective stiffness of the fibrosa layer is greater than that of the ventricularis layer in intact aortic valve leaflets (p<0.01). To characterize the viscoelastic properties of VICs, an inverse FE method of single cell MA was developed and compared with the analytical half-space model. It was found that inherent differences in the half-space and FE models of single cell MA yield different cell viscoelastic material parameters. However, under particular experimental conditions, the parameters estimated by the half-space model are statistically indistinguishable from those predicted by the FE model. To study strain transduction from the ECM to cytoskeleton, an improved texture correlation algorithm and a uniaxial tension release device were developed. It was found that substrate strain fully transfers to the cytoskeletal network via focal adhesions in live VICs under large strain tension release. To study the effects of cell-ECM interactions on VIC survival, two mechanical stimulus systems that can simulate the separate effects of cell contraction and cell monolayer detachment were developed. It was found that cell sheet detachment and disrupted cell-ECM signaling is likely responsible for the apoptosis of VICs grown in culture on thin collagen matrices, leading to calcification. The studies presented in this thesis refine existing biomechanical tools and provide new experimental and analytical tools with which to study cell-ECM interactions. Their application resulted in an improved understanding of hierarchical valve biomechanics, mechanotransduction, and mechanobiology.

Calcific aortic valve disease (CAVD) is one of the most common causes of cardiovascular disease in North America. Mechanical factors have been closely linked to the pathogenesis of CAVD and may contribute to the disease by actively regulating the mechanobiology of valve interstitial cells (VICs). Mechanical forces affect VIC function through interactions between the VIC and the extracellular matrix (ECM). Studies have shown that the transfer of mechanical stimulus during cell-ECM interaction depends on the local material properties at hierarchical length scales encompassing tissue, cell and cytoskeleton. In this thesis, biomechanical tools were developed and applied to investigate hierarchical cell-ECM interactions, using VICs and valve tissue as a model system. Four topics of critical importance to understanding VIC-ECM interactions were studied: focal biomechanical material properties of aortic valve tissue; viscoelastic properties of VICs; transduction of mechanical deformation from the ECM to the cytoskeletal network; and the impact of altered cell-ECM interactions on VIC survival. To measure focal valve tissue properties, a micropipette aspiration (MA) method was implemented and validated. It was found that nonlinear elastic properties of the top layer of a multilayered biomaterial can be estimated by MA by using a pipette with a diameter smaller than the top layer thickness. Using this approach, it was shown that the effective stiffness of the fibrosa layer is greater than that of the ventricularis layer in intact aortic valve leaflets (p<0.01). To characterize the viscoelastic properties of VICs, an inverse FE method of single cell MA was developed and compared with the analytical half-space model. It was found that inherent differences in the half-space and FE models of single cell MA yield different cell viscoelastic material parameters. However, under particular experimental conditions, the parameters estimated by the half-space model are statistically indistinguishable from those predicted by the FE model. To study strain transduction from the ECM to cytoskeleton, an improved texture correlation algorithm and a uniaxial tension release device were developed. It was found that substrate strain fully transfers to the cytoskeletal network via focal adhesions in live VICs under large strain tension release. To study the effects of cell-ECM interactions on VIC survival, two mechanical stimulus systems that can simulate the separate effects of cell contraction and cell monolayer detachment were developed. It was found that cell sheet detachment and disrupted cell-ECM signaling is likely responsible for the apoptosis of VICs grown in culture on thin collagen matrices, leading to calcification. The studies presented in this thesis refine existing biomechanical tools and provide new experimental and analytical tools with which to study cell-ECM interactions. Their application resulted in an improved understanding of hierarchical valve biomechanics, mechanotransduction, and mechanobiology.

Submitted in partial compliance with the requirements for the Master’s Degree in Technology: Chiropractic, Durban University of Technology, 2014. / Background: Myofascial Pain and Dysfunction (MPD) is a diagnosis commonly encountered by practitioners, hence, there are several treatment approaches employed by various practicing physicians. Practitioners are required to perform evidence-based protocols on patients; however, such intervention becomes increasingly difficult with the increasing volume of evidence available with regards to treatment of MPD. A systematic review provides a well-structured, critical analysis of the available protocols, and as such, provides practitioners with an evidence-based summary of the available modalities and the effectiveness of these modalities. Thus, the aim of the study was to systematically review and evaluate the literature to determine the effects of various non-invasive modalities on MPD. Objectives: Studies investigating various non-invasive modalities were identified, evaluated against the inclusion criteria and then reviewed against PEDro criteria to present current available evidence regarding their effectiveness as a source of treatment for MPD. Methods: A literature search was conducted, based on key terms including: active and latent myofascial trigger points, manual therapy, manipulation, acupressure, massage, muscle stretching, ultrasound, transcutaneous electric nerve stimulation, electric stimulation therapy, magnetic field therapy, and exercise therapy. Databases searched were: PubMed, EBSCOhost, Medline, CINAL, Proquest, Health Source, Sport Discus, Science Direct, Springer Link, Google Scholar and Summons. The articles were screened according to inclusion and exclusion criteria, after which a secondary hand and reference searches were performed. Thereafter, the articles were reviewed by four independent reviewers and the researcher. The PEDro Scale was used to determine methodological rigor of the included studies. The results were then analysed and ranked. Results: Following the screening process during data collection for this study, a total of 25 studies were identified and included. The review and ranking of these studies revealed a moderate level of evidence present for the effectiveness of Topical Agents. A limited level of evidence was noted for TENS, Ischemic Compression, Ultrasound, Laser and Other Modalities. Approximately 25% of the reviewed studies involved combination therapies; hence their outcomes cannot be applied to the effectiveness of individual modalities. Conclusion: Upon comparison of the quality of evidence available for the various types of modalities present for the treatment of MPD, it was noted that Topical Agents were supported by a stronger level of evidence than TENS, Ischeamic Compression, Ultrasound, Laser and Other Modalities. However, due to a lack of strong overall evidence for any of these modalities it has been concluded that more research is required to establish which modality is in fact the most effective.

This work aims at creating and verifying the trainig plan which develops dynamic and endurance skills needed for the competition called {\clqq}Ocelový muž``. The dissertation comprises three parts. The first part deals with the competition {\clqq}Ocelový muž``, the problems concerning dynamic and endurance skills, sports training and other interconected aspects. The next part is devoted to compiled training plan and to the testing of dynamic and endurance skills. Acquired knowledge is discussed and its summary is stated in conclusion.

No description available.

<div>The orbits of interest for potential missions are stable or nearly stable to maintain long term presence for conducting scientific studies and to reduce the possibility of rapid departure. Near Rectilinear Halo Orbits (NRHOs) offer such stable or nearly stable orbits that are defined as part of the L1 and L2 halo orbit families in the circular restricted three-body problem. Within the Earth-Moon regime, the L1 and L2 NRHOs are proposed as long horizon trajectories for cislunar exploration missions, including NASA's upcoming Gateway mission. These stable or nearly stable orbits do not possess well-distinguished unstable and stable manifold structures. As a consequence, existing tools for stationkeeping and transfer trajectory design that exploit such underlying manifold structures are not reliable for orbits that are linearly stable. The current investigation focuses on leveraging stretching direction as an alternative for visualizing the flow of perturbations in the neighborhood of a reference trajectory. The information supplemented by the stretching directions are utilized to investigate the impact of maneuvers for two contrasting applications; the stationkeeping problem, where the goal is to maintain a spacecraft near a reference trajectory for a long period of time, and the transfer trajectory design application, where rapid departure and/or insertion is of concern.</div><div><br></div><div>Particularly, for the stationkeeping problem, a spacecraft incurs continuous deviations due to unmodeled forces and orbit determination errors in the complex multi-body dynamical regime. The flow dynamics in the region, using stretching directions, are utilized to identify appropriate maneuver and target locations to support a long lasting presence for the spacecraft near the desired path. The investigation reflects the impact of various factors on maneuver cost and boundedness. For orbits that are particularly sensitive to epoch time and possess distinct characteristics in the higher-fidelity ephemeris model compared to their CR3BP counterpart, an additional feedback control is applied for appropriate phasing. The effect of constraining maneuvers in a particular direction is also investigated for the 9:2 synodic resonant southern L2 NRHO, the current baseline for the Gateway mission. The stationkeeping strategy is applied to a range of L1 and L2 NRHOs, and validated in the higher-fidelity ephemeris model.</div><div><br></div><div>For missions with potential human presence, a rapid transfer between orbits of interest is a priority. The magnitude of the state variations along the maximum stretching direction is expected to grow rapidly and, therefore, offers information to depart from the orbit. Similarly, the maximum stretching in reverse time, enables arrival with a minimal maneuver magnitude. The impact of maneuvers in such sensitive directions is investigated. Further, enabling transfer design options to connect between two stable orbits. The transfer design strategy developed in this investigation is not restricted to a particular orbit but applicable to a broad range of stable and nearly stable orbits in the cislunar space, including the Distant Retrograde Orbit (DROs) and the Low Lunar Orbits (LLO) that are considered for potential missions. Examples for transfers linking a southern and a northern NRHO, a southern NRHO to a planar DRO, and a southern NRHO to a planar LLO are demonstrated.</div>