Submitted by Fabio Sobreira Campos da Costa (fabio.sobreira@ufpe.br) on 2016-07-22T12:19:51Z No. of bitstreams: 2 license_rdf: 1232 bytes, checksum: 66e71c371cc565284e70f40736c94386 (MD5) CAPA da dissertação COM CORRECOES DA BANCA ARQ unico 3 pdf.pdf: 2378442 bytes, checksum: 65fd4f0e4b5a3d33ed5be58bcd1d663e (MD5) / Made available in DSpace on 2016-07-22T12:19:51Z (GMT). No. of bitstreams: 2 license_rdf: 1232 bytes, checksum: 66e71c371cc565284e70f40736c94386 (MD5) CAPA da dissertação COM CORRECOES DA BANCA ARQ unico 3 pdf.pdf: 2378442 bytes, checksum: 65fd4f0e4b5a3d33ed5be58bcd1d663e (MD5) Previous issue date: 2016-02-03 / FACEPE / A adolescência é um período propenso ao desenvolvimento da insatisfação com o próprio corpo. A distorção da imagem corporal, em conjunto com a baixa autoestima, são os responsáveis pela busca incessante de emagrecimento, levando a comportamentos prejudiciais à saúde. Desta forma, são considerados fatores que podem desencadear sintomas de bulimia nervosa. Suas primeiras manifestações são na adolescência, podendo apresentar efeitos nocivos sobre a saúde bucal. Assim, este estudo teve como objetivo avaliar fluxo e pH salivar associados à presença de erosão dental em adolescentes com sintomas de bulimia nervosa. Tratou-se de um estudo descritivo e transversal com adolescentes de ambos os sexos, na faixa etária de 10 a 19 anos, estudantes de escolas públicas da rede estadual de educação do Estado de Pernambuco. Os instrumentos utilizados foram: questionário biodemográfico; Teste de Avaliação Bulímica de Edinburgh – BITE, em sua versão para adolescentes; uma ficha clínica odontológica para o preenchimento do Índice de Desgaste Dentário e um questionário de hábitos alimentares. A prevalência de sintomas de bulimia nervosa na população estudada foi de 44,0% de acordo com o Teste de Avaliação Bulímica de Edinburgh e deste total, 39,0% apresentaram escore médio e 5,0%, escore elevado. Em 57,7% dos adolescentes foi encontrada erosão dental. Apenas 14,9% e 2,7% da amostra apresentaram hipossalivação e pH salivar ácido, respectivamente. Houve associação significativa dos sintomas de bulimia nervosa com erosão dental, porém não foi verificado associação entre fluxo e pH salivar com erosão dental. Em relação ao grupo de dentes e faces, a presença de erosão concentrou-se nos dentes anteriores (incisivos centrais e laterais) nas faces linguais/palatinas, havendo associação com a presença de sintomas de bulimia nervosa. Após a análise dos dados pode-se concluir que a erosão dental está intimamente relacionada com a bulimia nervosa, assim como o consumo de refrigerantes e a frequência de escovação dental. O conhecimento dessas alterações por parte do cirurgião-dentista possibilitará o encaminhamento do adolescente a um tratamento integral, que envolve a participação de uma equipe multidisciplinar, evitando o agravo do transtorno e contribuindo com o diagnóstico precoce. / Adolescence is a period prone to the development of dissatisfaction with the body. The body image distortion along with low self-esteem are responsible for the relentless pursuit of weight loss, leading to unhealthy behaviors, and therefore factors that may trigger some symptoms of bulimia nervosa. These first manifestations are in adolescence and may have harmful effects on oral health. This study aimed to evaluate flow and salivary pH associated with the presence of dental erosion in adolescents with symptoms of bulimia nervosa. It was a descriptive, cross-sectional study with adolescents of both sexes, aged 10 to 19 years old, public state school students in Pernambuco. The instruments used were: a biodemographic questionnaire; Bulimic Investigatory Test Edinburgh - BITE, in its version for adolescents, a dental clinic file for filling the Tooth Wear Index and a questionnaire of food habits. The prevalence of symptoms of bulimia nervosa in the population studied was 44.0% according to the Bulimic Investigatory Test Edinburgh and of this total 39.0% had average score and 5.0% had a high score 5.0%. In 57.7% of teenagers found dental erosion. Only 14.9% and 2.7% had hyposalivation and salivary pH acid, respectively. There was a significant association of the symptoms of bulimia nervosa with dental erosion, but it has not been verified association between salivary flow and pH with dental erosion. Regarding the group of teeth and faces, the presence of erosion focused on anterior teeth (central incisors and lateral) on the lingual / palatal, having association with the presence of symptoms of bulimia nervosa. After analyzing the data, it can be concluded that dental erosion is closely related to bulimia nervosa, as well as soft drink consumption and frequency of tooth brushing. Knowledge of these changes on the part of the dentist may allow the teenager's referral to a full treatment, which involves the participation of a multidisciplinary team, avoiding the inconvenience of injury or even its appearance.

Background: Radiation therapy used for head and neck cancer patients cause many side effects in the oral cavity and above all affects the salivary glands. Complaint of dry mouth (xerostomia) and hyposalivation are common as well as swallowing difficulty (dysphagia) even after the cancer is remitted.  Aim: The aim of the study is to examine the correlation between hyposalivation and xerostomia in patients undergoing radiotherapy.   Methods: Six patients undergoing radiotherapy for head and neck cancer at Norrlands University Hospital participated in the study. A questionnaire regarding xerostomia was answered and a collection of stimulated as well as unstimulated saliva was taken.  Results: Regarding the stimulated salivary flowrate, one out six patients was below the limit of hyposalivation. Three out of six patients were below the limit of hyposalivation with reference to the unstimulated salivary output. The questionnaire regarding xerostomia showed that all patients experienced dry mouth symptoms to varying degrees. The questions concerning the dryness of the tongue and the amount of saliva in the mouth had the highest rating.  Conclusion: Regarding the patients that participated in this study, a correlation is shown between xerostomia and unstimulated salivary output. However, due to the lack of participants in the study, no firm conclusion can be drawn.

Time-based sensory analysis techniques capture the dynamic retronasal and mouthfeel sensations in wines. It is important to understand how common winemaking practices and popular varietals impact the retronasal and mouthfeel profile as consumers tend to judge wine quality based on the taste, flavor, and mouthfeel of a wine. Three time-based sensory analysis methods were utilized with the objective to understand the effect of five commonly applied winemaking techniques (blending, varietal choice, fermentation temperature, cap management, and stem addition) on the dynamic retronasal and mouthfeel profile of six different varietals (Merlot, Malbec, Petite Sirah, Pinot noir, Grenache, and Tannat) grown on the Central Coast of California. An additional objective was to account for panelist salivary flow rate and its impact on the time and rate of perception of astringency and selected retronasal aromas during time-based evaluations. Finally, as descriptive analysis was employed in three of the studies to assess color and orthonasal aroma, which is an effective static method but requires a lot of training time, the use of a rapid method known as Pivot© Profile was utilized to assess Syrah wines from the Central Coast of California. Temporal Dominance of Sensations (TDS) was utilized to determine if there were significant differences between cofermented and blended wines as well as the impact of varietal choice. TDS curves (n=11) demonstrated that varietal choice was more impactful on the retronasal profile than blending time. Chemical analysis indicated that post-malolactic fermentation wines had higher titratable acidity, while cofermented wines had higher tannins. Indeed, the differences between blending times were subtle but were reflected in the TDS curves. Therefore, it was recommended to employ post-alcoholic or post-malolactic fermentation blending over cofermentation. TDS was also utilized to understand the impact of whole cluster, stem addition, and wine sipping volume on the temporal sensory profile of Tannat wines. Similar to the previous study, TDS curves (n=10) were able to reflect differences in astringency, acidity, and hot perception which were apparent in basic and phenolic chemistry. Indeed, the combination of Tannat and stem addition led to wines with a long (34.6 seconds) perceived dominance of astringency. Volatile chemistry indicated that the use of whole cluster in Tannat wines led to higher concentrations of phenylethyl alcohol, β-damascenone, and the terpene, trans-farnesol, compared to the control, and other stem addition wines. Therefore, it was recommended to explore whole cluster addition in Tannat for future research over the green and dried stem wines. Time-Intensity (TI) and Temporal Check-All-That-Apply (TCATA), were utilized to understand the effect of alcohol fermentation temperature and cap management regimes in Pinot noir and Grenache wines. TI results (n=13) suggested that fermentation temperature had more of an impact on the mouthfeel and retronasal profile of Pinot wines than cap management. Indeed, while Hot fermentation temperature wines led to more intense astringency perception relative to the other treatments, Cold fermentation temperature wines led to higher perception of retronasal flavor which was also reflected in the volatile chemistry. As for Grenache, the results were more complicated as this variety was sensitive to both oxidation and reduction aromas. TCATA (n=8) and volatile chemistry results indicated that the treatment with the most balance of retronasal fruit and astringency with minimal reduction flavor were the Cold/Hot PD wines. The results of both studies suggested that both fermentation temperature and cap management regime were indeed varietal dependent. When using time-based sensory analysis, it is important to account for salivary flow rate, an inherent physiological characteristic, that affects the time and perception of astringency and retronasal aromas. Past research has utilized TI to examine this phenomenon, whereby low salivary flow rate individuals typically perceived astringency later and more intensely than high salivary flow rate individuals. For retronasal aromas, it depends on the associated volatile compound. For example, fruit aromas which are associated with esters are typically perceived by high salivary flow rate individuals as later and more intensely than low salivary flow rate individuals. Since tracking salivary flow rate has been exclusively used in TI, methods were developed in the present study to examine the time of first dominance in TDS and time of first perception in TCATA. Throughout each study, the pattern of astringency perception followed previous reports with two exceptions. In the Pinot noir wines, higher salivary flow rate panelists had their time of maximum intensity later than low salivary flow rate panelists. However, the time of first perception, maximum intensity, and area under curve were still significantly later and higher in low salivary flow rate panelists. With the Tannat wines, high salivary flow rate individuals had significantly later time of dominance for astringency than low salivary flow rate panelists. In this case, it was thought to be because only one parameter was being assessed for this pattern whereas the inclusion of area under curve or maximum citation proportion by group may provide more information. Finally, the use of a modified Pivot© Profile with an expert panel (n=15) was examined in Syrah wines that underwent different cap management and maceration techniques as well as different ethanol levels. Results indicated that modified Pivot© Profile was effective for differentiating color and orthonasal aroma attributes by cap management style. However, modified Pivot© Profile was not able to reflect the differences seen in the basic and volatile chemistry specifically the effect of ethanol level on malolactic fermentation. Therefore, it was recommended to use modified Pivot© Profile for color and orthonasal aroma but employ a time-based sensory method for understanding the retronasal and mouthfeel profile as it can reflect differences in chemistry more effectively. Overall, the employment of time-based sensory analysis to examine the dynamic retronasal and mouthfeel profile in red wine was worthwhile, as these methods can subtly reflect differences in chemistry as well as assist in making practical winemaking decisions.

O objetivo deste trabalho é analisar o Risco de Cárie através de variáveis microbiológicas: Risco Bacteriológico e da Resazurina (RB e RE); e de variáveis clínicas (superfícies de cárie, índice CPOS, manchas brancas e velocidade de fluxo salivar) designadas RF, num estudo longitudinal de 2 anos. A amostra inicial era de 97 escolares (11-13 anos) resgatando-se 55 ao final. Utilizou-se a técnica estatística Análise de Variância (ANOVA) e Comparações Múltiplas pelo Método de Tukey, com 5 por cento de significância, além do Teste de McNemar para verificar se RF era um bom triador dos grupos de risco. Os resultados mostraram que o teste RB (contagem de Streptococcus mutans na saliva) conseguiu determinar o grupo de alto risco que apresentou maior incidência de cáries. Este grupo foi melhor identificado quando a variável resposta foi incidência de cáries mais incidência de manchas brancas do que somente a incidência de cáries. Estes resultados foram semelhantes para RF. Não se conseguiu com RE, no entanto, diferenciar os grupos de risco ao nível de 5% de significância. Assim, conclui-se que tanto a variável microbiológica (RB) como as clínicas são bons parâmetros para determinar o grupo de alto risco de cárie. / The purpose of the present study was to analyse the Risk of Caries, through microbials variables - Bacteriology and Resazurin Risk (RB and RE); and clinical variables (RF) over a 2-yr period. Data are based on 97 school children (11-13 years old), recovering 55 at the final of the study. ANOVA and Tukey Test were applied at 5 per cent of significance, in addition the McNemar Test was applied to verify if RF was a good selector of the risk groups. The results showed that RB Test (number of Streptococcus mutans in saliva) identified people at higher risk of developing dental caries. This group was better identified when the resultant variable was incidence of caries plus incipient smooth surface lesions than only incidence of caries. These results were the same for RF. RE can\'t identify the groups of risk at 5 per cent of significance. It was concluded that both microbial (RB), and clinical variables were good parameters to identify people at high caries risk.

O objetivo deste trabalho é analisar o Risco de Cárie através de variáveis microbiológicas: Risco Bacteriológico e da Resazurina (RB e RE); e de variáveis clínicas (superfícies de cárie, índice CPOS, manchas brancas e velocidade de fluxo salivar) designadas RF, num estudo longitudinal de 2 anos. A amostra inicial era de 97 escolares (11-13 anos) resgatando-se 55 ao final. Utilizou-se a técnica estatística Análise de Variância (ANOVA) e Comparações Múltiplas pelo Método de Tukey, com 5 por cento de significância, além do Teste de McNemar para verificar se RF era um bom triador dos grupos de risco. Os resultados mostraram que o teste RB (contagem de Streptococcus mutans na saliva) conseguiu determinar o grupo de alto risco que apresentou maior incidência de cáries. Este grupo foi melhor identificado quando a variável resposta foi incidência de cáries mais incidência de manchas brancas do que somente a incidência de cáries. Estes resultados foram semelhantes para RF. Não se conseguiu com RE, no entanto, diferenciar os grupos de risco ao nível de 5% de significância. Assim, conclui-se que tanto a variável microbiológica (RB) como as clínicas são bons parâmetros para determinar o grupo de alto risco de cárie. / The purpose of the present study was to analyse the Risk of Caries, through microbials variables - Bacteriology and Resazurin Risk (RB and RE); and clinical variables (RF) over a 2-yr period. Data are based on 97 school children (11-13 years old), recovering 55 at the final of the study. ANOVA and Tukey Test were applied at 5 per cent of significance, in addition the McNemar Test was applied to verify if RF was a good selector of the risk groups. The results showed that RB Test (number of Streptococcus mutans in saliva) identified people at higher risk of developing dental caries. This group was better identified when the resultant variable was incidence of caries plus incipient smooth surface lesions than only incidence of caries. These results were the same for RF. RE can\'t identify the groups of risk at 5 per cent of significance. It was concluded that both microbial (RB), and clinical variables were good parameters to identify people at high caries risk.

Linha de pesquisa: Epidemiologia e controle das doen?as bucais. / ?rea de concentra??o: Odontopediatria. / Submitted by Jos? Henrique Henrique (jose.neves@ufvjm.edu.br) on 2017-01-09T17:58:21Z No. of bitstreams: 2 license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5) debora_souto_souza.pdf: 1070377 bytes, checksum: 562fbb6f4882bd48d44c79a12642d975 (MD5) / Approved for entry into archive by Rodrigo Martins Cruz (rodrigo.cruz@ufvjm.edu.br) on 2017-01-10T13:23:52Z (GMT) No. of bitstreams: 2 license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5) debora_souto_souza.pdf: 1070377 bytes, checksum: 562fbb6f4882bd48d44c79a12642d975 (MD5) / Made available in DSpace on 2017-01-10T13:23:52Z (GMT). No. of bitstreams: 2 license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5) debora_souto_souza.pdf: 1070377 bytes, checksum: 562fbb6f4882bd48d44c79a12642d975 (MD5) Previous issue date: 2016 / Coordena??o de Aperfei?oamento de Pessoal de N?vel Superior (CAPES) / Funda??o de Amparo a Pesquisa do Estado de Minas Gerais (FAPEMIG) / Conselho Nacional de Desenvolvimento Cient?fico e Tecnol?gico (CNPq) / Objetivo: Avaliar a associa??o entre condi??es bucais, limiar de degluti??o e performance mastigat?ria de crian?as pr?-escolares. Metodologia: Um estudo transversal foi realizado com uma amostra composta por 127 crian?as entre tr?s e cinco anos de idade. O fluxo salivar, a presen?a de c?rie cavitada na regi?o posterior, o n?mero de dentes presentes e o n?mero de unidades oclusais foram as condi??es bucais avaliadas. Al?m disso, foram analisados o n?mero de ciclos mastigat?rios at? a degluti??o, o tamanho mediano da particular no limiar de degluti??o e na performance mastigat?ria. Essas avalia??es foram conduzidas utilizando um material teste (Optocal), que foi processado pela t?cnica de peneiragem e o tamanho mediano da part?cula (X50) foi avaliado pela equa??o de Rosin-Rammler. A an?lise dos dados foi realizada utilizando-se o programa Statistical Package for the Social Sciences (SPSS) para Windows, vers?o 22.0 e incluiu a descri??o de frequ?ncia das vari?veis, teste de correla??o de Spearman, an?lise de regress?o linear simples e m?ltipla. Resultados: Considerando o n?mero de ciclos como vari?vel dependente, somente o tamanho mediano das part?culas no limiar de degluti??o permaneceu associado a esta vari?vel (p<0,001). O tamanho mediano das part?culas na performance mastigat?ria (p<0,001) e o n?mero de ciclos (p<0,001) foram associados ao tamanho mediano das part?culas no limiar de degluti??o quando esta vari?vel foi considerada dependente. Utilizando o tamanho mediano das part?culas na performance mastigat?ria como vari?vel dependente, o n?mero de dentes (p<0,001) e o tamanho mediano das part?culas no limiar de degluti??o (p<0,001) foram as vari?veis que permaneceram associadas. Conclus?o: Um maior n?mero de ciclos mastigat?rios foi associado a um menor tamanho mediano da part?cula no limiar de degluti??o e o tamanho mediano da part?cula no limiar de degluti??o foi associado ? performance mastigat?ria e ao n?mero de ciclos mastigat?rios. Um arco dent?rio mais completo e um menor tamanho mediano da part?cula no limiar de degluti??o foram associados a uma melhor performance mastigat?ria. / Disserta??o (Mestrado) ? Programa de P?s-Gradua??o em Odontologia, Universidade Federal dos Vales do Jequitinhonha e Mucuri, 2016. / Aim: Assess the association between oral conditions swallowing threshold and masticatory performance of preschool children. Methods: A cross-sectional study was performed with 127 children between three and five years old. The oral conditions evaluated were salivary flow, the presence of cavitated caries in posterior teeth, the number of teeth and the number of occlusal units. In addition, we analyzed the number of masticatory cycles to swallowing, particularly the median size in the threshold swallowing and masticatory performance. These evaluations were conducted using a test material (Optocal), which was processed by sieving technique and the median particle size (X50) was evaluated by the equation of Rosin-Rammler. Data analysis was performed using the Statistical Package for Social Sciences (SPSS) for Windows, version 22.0 and included a description of variables frequency, Spearman correlation test, analysis of simple and multiple linear regression. Results: Considering the number of cycles as the dependent variable, only the median particle size in the swallowing threshold remained associated with this variable (p <0.001). The median particle size in the masticatory performance ( p <0.001) and the number of cycles (p <0.001) were associated with median particle size in swallowing threshold when this variable was considered to be dependent. Using the median particle size of the masticatory performance as the dependent variable, the number of teeth (p <0.001) and the median particle size in swallowing threshold (p <0.001) were the variables that remained associated. Conclusion: A larger number of masticatory cycles was associated with a lower median particle size in the swallowing threshold, the median particle size in the swallowing threshold was associated with masticatory performance and the number of masticatory cycles. A fuller dental arch and a lower median particle size in the swallowing threshold were associated with a better masticatory performance.

Made available in DSpace on 2014-06-11T19:28:03Z (GMT). No. of bitstreams: 0 Previous issue date: 2004-02-12Bitstream added on 2014-06-13T18:07:23Z : No. of bitstreams: 1 pires_jr_dr_arafo.pdf: 422001 bytes, checksum: 5fdba3ee936d59216f9c3b7bd4ad41a3 (MD5) / Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) / O objetivo deste estudo foi avaliar os efeitos do tratamento periodontal em pacientes diabéticos do tipo 2 sobre alterações de fluxo salivar, xerostomia, Candida spp. na saliva e candidose bucal clínica. Foram selecionados 20 pacientes diabéticos tipo 2 e 17 pacientes não-diabéticos de ambos os gêneros, com idade média entre 37 e 55 anos, portadores de doença periodontal crônica. Após exame clínico para avaliação das condições clínicas periodontais, presença de xerostomia e presença clínica de candidose bucal, amostras de saliva foram coletadas para mensuração do fluxo salivar (mL/min), contagem das colônias de Candida spp. (UFC/mL) e identificação das espécies. Esse procedimento foi realizado antes da terapia periodontal (baseline), que consistiu em raspagem e alisamento radicular, instrução de higiene bucal e motivação do paciente, aos 30 e 90 dias após a mesma. Os resultados demonstraram que os pacientes diabéticos apresentaram maior ocorrência de xerostomia e de candidose bucal, sendo estes colonizados por várias espécies de Candida spp. com predominância de C. albicans, sem no entanto, implicar no desenvolvimento da candidose clinicamente. A terapia periodontal, a motivação do paciente e a instrução de higiene bucal foram importantes para melhorar as condições clínicas periodontais e evitar a formação de reservatórios intrabucais de infecção. / In order to investigate the effect of periodontal therapy, in type 2 diabetes mellitus subjects about salivar flow rates, presence of xerostomia, presence of Candida species in the saliva and presence of buccal candidose, twenty type 2 diabetes mellitus subjects and seventeen no-diabetes mellitus subjects, with medium age among 33 to 55 years, presenting generalized chronic periodontal disease were selected. After initial clinical exam to analyze periodontal parameters, xerostomia and buccal candidose presence, saliva samples were assessed to quantify as millimeters of saliva generated per minute (mL/min), account yeasts by colony forming units per mL (CFU/mL) and identificated species. That procedure was accomplished before periodontal therapy (baseline) that it consisted in scaling and root planning, oral hygiene instructions and patient's motivation to the thirty and ninety days after these. Diabetics subjects showed to having hyposalivation in similar levels in no-diabetics groups and in all the analyzed periods, higher prevalence of xerostomia and higher occurrence of buccal candidose. Candida albicans were the prevalent yeast at all periods in both groups, but the presence of yeasts in saliva not implied in the development of buccal candidose. Concluded that the periodontal therapy, the patients' motivation and the buccal hygiene instructions improve periodontal conditions and avoid the formation of microbial reservoirs in mouth.

Orientador: Denise Madalena Palomari Spolidorio / Banca: Elaine Maria Sgavioli Massucato / Banca: Antonio Olavo Cardoso Jorge / Resumo: O objetivo deste estudo foi avaliar os efeitos do tratamento periodontal em pacientes diabéticos do tipo 2 sobre alterações de fluxo salivar, xerostomia, Candida spp. na saliva e candidose bucal clínica. Foram selecionados 20 pacientes diabéticos tipo 2 e 17 pacientes não-diabéticos de ambos os gêneros, com idade média entre 37 e 55 anos, portadores de doença periodontal crônica. Após exame clínico para avaliação das condições clínicas periodontais, presença de xerostomia e presença clínica de candidose bucal, amostras de saliva foram coletadas para mensuração do fluxo salivar (mL/min), contagem das colônias de Candida spp. (UFC/mL) e identificação das espécies. Esse procedimento foi realizado antes da terapia periodontal (baseline), que consistiu em raspagem e alisamento radicular, instrução de higiene bucal e motivação do paciente, aos 30 e 90 dias após a mesma. Os resultados demonstraram que os pacientes diabéticos apresentaram maior ocorrência de xerostomia e de candidose bucal, sendo estes colonizados por várias espécies de Candida spp. com predominância de C. albicans, sem no entanto, implicar no desenvolvimento da candidose clinicamente. A terapia periodontal, a motivação do paciente e a instrução de higiene bucal foram importantes para melhorar as condições clínicas periodontais e evitar a formação de reservatórios intrabucais de infecção. / Abstract: In order to investigate the effect of periodontal therapy, in type 2 diabetes mellitus subjects about salivar flow rates, presence of xerostomia, presence of Candida species in the saliva and presence of buccal candidose, twenty type 2 diabetes mellitus subjects and seventeen no-diabetes mellitus subjects, with medium age among 33 to 55 years, presenting generalized chronic periodontal disease were selected. After initial clinical exam to analyze periodontal parameters, xerostomia and buccal candidose presence, saliva samples were assessed to quantify as millimeters of saliva generated per minute (mL/min), account yeasts by colony forming units per mL (CFU/mL) and identificated species. That procedure was accomplished before periodontal therapy (baseline) that it consisted in scaling and root planning, oral hygiene instructions and patient's motivation to the thirty and ninety days after these. Diabetics subjects showed to having hyposalivation in similar levels in no-diabetics groups and in all the analyzed periods, higher prevalence of xerostomia and higher occurrence of buccal candidose. Candida albicans were the prevalent yeast at all periods in both groups, but the presence of yeasts in saliva not implied in the development of buccal candidose. Concluded that the periodontal therapy, the patients' motivation and the buccal hygiene instructions improve periodontal conditions and avoid the formation of microbial reservoirs in mouth. / Mestre

Orientador: Jaime Aparecido Cury / Dissertação (mestrado) - Universidade Estadual de Campinas, Faculdade de Odontologia de Piracicaba / Made available in DSpace on 2018-07-25T22:05:28Z (GMT). No. of bitstreams: 1 Queiroz_CelsoSilva_M.pdf: 4148499 bytes, checksum: a250fc32bc9b3c95e74bc4505b1ca920 (MD5) Previous issue date: 1999 / Resumo: O objetivo do trabalho foi avaliar a relação entre o estresse e a concentração dos compostos sulfurados voláteis (CSV) no hálito bucal. Para tanto, foram avaliadas duas condições estressantes: Estudo I - prova; Estudo II - tensão pré-menstrual (TPM). O Estudo I foi composto de 2 grupos: A e B. O grupo A (34 voluntários), foi subdividido em 18 voluntários com estresse e 16 voluntários sem estresse. As concentrações dos CSV e foram medidas 1 semana antes da prova, no dia e 1 semana após, através do monitor de sulfetos (Halimeter) e o fluxo salivar também foi mensurado. No grupo B (37 voluntários), além dessas análises foram mensurados o pH, "capacidade tampão", cálcio, fósforo e proteína na saliva. O Estudo II foi composto por 50 voluntárias: 27 mulheres sem TPM (controle) e 23 mulheres com TPM. As mensurações dos CSV e do fluxo salivar foram realizadas nos períodos não-menstrual, pré-menstrual e de menstruação. A análise estatística mostrou que tanto no Grupo A (n=34) quanto no Grupo B (n=37) a concentração dos CSV no dia da prova foi maior (p<0,05) enquanto que a taxa de fluxo salivar foi menor (p<0,05). Os voluntários com estresse (n=18) e sem estresse (n=16) também apresentaram maiores concentrações de CSV no dia da prova (p<0,05), enquanto o fluxo salivar foi menor somente nos voluntários não estressados (p<0,05). A análise bioquímica da saliva do Grupo B revelou - que o pH foi menor no dia da prova (p<0,05), e as demais análises não foram diferentes (p>0,05). No Estudo II, as voluntárias sem TPM (n=26) apresentaram maior concentração dos CSV no período menstrual (p<0,05). Enquanto nas voluntárias com TPM (n=23) a concentração dos CSV foi maior (p<0,05) nos períodos menstrual e pré-menstrual. Já o fluxo salivar não mostrou diferenças (p>0,05). Os resultados sugerem que o estresse é um fator pré-disponente da halitose, cujo mecanismo não pode ser explicado somente pela diminuição do fluxo salivar / Abstract:The aim of study was to evaluate the relationship between stress and volatile sulfur compounds (VSC) present in mouth air. Thus, two stressfull conditions were evaluated: Study 1- examination; Study II - premenstrual syndrome (PMS). Study I was composed of 2 groups: A and B. Group A (34 volunteers), was divided in 18 volunteers with stress and 16 volunteers without stress. VSC concentrations were measured a week before, on day and a week after the exam using a sulfide monitor (Halimeter) and the salivary flow was measured. In group B (37 volunteers), others analyisis as pH, "buffer capacity", proteins, calcium and phosphorus, in saliva were performed. In study II, fifty women were selected: 27 women without PMS symptoms (control group) and 23 women with PMS symptoms. The measurements were performed during non-menstrual, PMS and menstrual periods. The statistical results showed in both groups A and B an increase of VSC concentration on the exam day (p<0.05) and the salivary flow was lower (p<0.05). Volunteers with stress (n=18) and without stress (n=16), presented higher VSC concentration on the exam (p<0.05), but there was statistical diferences in the salivary flow rate only in the volunteers without stress (p<0.05). The biochemistry analisys of the saliva in group B showed that pH was lower on the exam day (p<0.05), and others analisys were not statistical differences (p>0.05). In study II, the volunteers without PMS symptoms (n=26) presented higher VSC concentration in the menstrual period (p<0.05). Volunteers with PMS (h=23) showed a greater VSC concentration in both menstrual and PMS periods (p<0.05). Salivary flow rate was not statistically different (p>0.05). The results suggest that stressful conditions can be a predisposing factor for bad breath, and the mechanism cannot be explained only by the decrease of the salivary flow / Mestrado / Fisiologia Oral / Mestre em Odontologia

Made available in DSpace on 2015-05-14T12:56:01Z (GMT). No. of bitstreams: 1 parte 1.pdf: 286274 bytes, checksum: 680b6739458bd32bbb943941a13dc712 (MD5) Previous issue date: 2007-12-05 / Coordenação de Aperfeiçoamento de Pessoal de Nível Superior - CAPES / Diabetes mellitus is an endocrine disease, which causes alteration in assimilation, metabolism and balance of the blood glucose concentration. It is believed that the high level of blood glucose is linked to the development of buccal alterations; however, there is some controversy in the studies that aim to compare the concentration of blood and salivary glucose in diabetic patients. The objective of this paper is to comparatively evaluate the concentration of blood and salivary glucose as well as the salivary flow and xerostomia in type 2 diabetic and non-diabetic patients. Eighty adult subjects of both sexes have been selected, being 40 adults diabetic of the experimental type and 40 adults non-diabetic belonging to control. The total in-rest and stimulated salivary flow has been determined as well as the concentration of peripheral blood and salivary glucose. Descriptive analysis was carried out and Mann-Whitney and qui-square tests were applied considering significant values of p<0,05. The average value of salivary glucose in diabetic patients was 14,03±16,76 mg/dl and in the control group, 6,35±6,02 mg/dl, with p= 0,036. The capillary blood glucose in diabetic patients presented an average value equivalent to 213,23±87,98 mg/dl and, in non-diabetic patients it was equivalent to 99,15±13,72 mg/dl, with p= 000. The average value for the in-rest salivary flow was 0,21±0,16 ml/min in diabetic patients and 0,33±0,20 ml/min in the control group with p= 0,002. The stimulated salivary flow was lower in the group of diabetic patients, with an average of 0,63±0,43 ml/min, in relation to the control group, which presented an 1,20±0,70 ml/min average, with p= 0,00. Out of the diabetic patients, 45% had hyposalivation contrasting to 2,5% out of the non-diabetic patients, with p=0,00. Xerostomia was reported in 12,5% of diabetic patients and 5% of non-diabetic patients, with p=0,23. We can conclude that the salivary glucose concentration was significantly higher in the experimental group and that there was no correlation between the salivary and blood glucose concentration in diabetic patients. The total salivary flows were significantly reduced in diabetic patients and there was no significant difference as to the presence of xerostomia in both groups. / O diabetes mellitus é uma doença endócrina que causa alteração na assimilação, metabolismo e equilíbrio da concentração da glicose sanguínea. Acredita-se que o elevado nível de glicose sangüínea esteja associado ao desenvolvimento de alterações bucais, porém, existe controvérsia nos estudos que objetivam comparar a concentração de glicose sanguínea e salivar em pacientes diabéticos. O objetivo do presente estudo foi avaliar comparativamente a concentração de glicose salivar e sanguínea, o fluxo salivar e a xerostomia em pacientes diabéticos tipo 2 e não diabéticos. Foram selecionados 80 indivíduos adultos, de ambos os sexos, sendo 40 adultos diabéticos pertencentes ao experimental e 40 adultos não diabéticos pertencentes ao controle. Determinou-se o fluxo salivar total em repouso e estimulado, a concentração de glicose salivar e sanguínea periférica. Realizou-se análise descritiva e aplicaram-se testes de Mann-Whitney e qui-quadrado, considerando significantes valores de p<0,05. O valor médio de glicose salivar nos diabéticos foi 14,03±16,76 mg/dl e, no grupo controle, 6,35±6,02 mg/dl, com p= 0,036. A glicose sanguínea capilar nos diabéticos apresentou valor médio equivalente a 213,23±87,98 mg/dl e, nos não diabéticos, a 99,15±13,72 mg/dl, com p= 000. O valor médio para o fluxo salivar em repouso foi de 0,21±0,16 ml/min nos diabéticos e 0,33±0,20 ml/min no grupo controle, com p= 0,002. O fluxo salivar estimulado foi inferior no grupo dos diabéticos, com média de 0,63±0,43 ml/min, em relação ao grupo controle que apresentou média 1,20±0,70 ml/min, com p= 0,00. Entre os diabéticos, 45% apresentaram hipossalivação, contrastando com os 2,5% entre os não diabéticos, com p=0,00. A xerostomia foi referida em 12,5% dos diabéticos e 5% dos não diabéticos, com p=0,23. Pode-se concluir que concentração de glicose salivar foi significativamente maior no grupo experimental e que não houve correlação entre a concentração da glicose salivar e glicose sanguínea nos indivíduos diabéticos. Os fluxos salivares totais mostraram-se significativamente reduzidos nos pacientes diabéticos e não houve diferença significativa quanto à presença de xerostomia em ambos os grupos.