• Refine Query
  • Source
  • Publication year
  • to
  • Language
  • 70
  • 20
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • Tagged with
  • 104
  • 24
  • 21
  • 18
  • 17
  • 16
  • 15
  • 15
  • 13
  • 13
  • 13
  • 12
  • 11
  • 11
  • 11
  • About
  • The Global ETD Search service is a free service for researchers to find electronic theses and dissertations. This service is provided by the Networked Digital Library of Theses and Dissertations.
    Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
1

Xerostomia clinical aspects, pathology and pathogenesis /

Bertram, Ulrik. January 1967 (has links)
Thesis--University of Copenhagen, 1967. / Includes bibliographical references (p. [116]-124).
2

Xerostomia clinical aspects, pathology and pathogenesis /

Bertram, Ulrik. January 1967 (has links)
Thesis--University of Copenhagen, 1967. / Includes bibliographical references (p.[116]-124).
3

A comparison of two saliva substitutes in the management of xerostomia during radiotherapy for cancer of the head and neck.

Lochner, Johann Georg. January 2007 (has links)
<p>The aim of the study is to compare the palliative efficacy of two saliva substitutes (Sinspeek and Xerostom) in patients during radiotherapy for cancer of the head and neck. This crossover randomised controlled clinical trial was carried out on twenty-five patients with malignant tumours of the head and neck, following four weeks of radiotherapy at tygerberg hospital. The benefit of saliva substitutes to ameliorate the effects of xerostomia is well established and proper advice and access to relevant preparations is essential.</p>
4

A comparison of two saliva substitutes in the management of xerostomia during radiotherapy for cancer of the head and neck.

Lochner, Johann Georg. January 2007 (has links)
<p>The aim of the study is to compare the palliative efficacy of two saliva substitutes (Sinspeek and Xerostom) in patients during radiotherapy for cancer of the head and neck. This crossover randomised controlled clinical trial was carried out on twenty-five patients with malignant tumours of the head and neck, following four weeks of radiotherapy at tygerberg hospital. The benefit of saliva substitutes to ameliorate the effects of xerostomia is well established and proper advice and access to relevant preparations is essential.</p>
5

A comparison of two saliva substitutes in the management of xerostomia during radiotherapy for cancer of the head and neck

Lochner, Johann Georg January 2007 (has links)
Magister Chirurgiae Dentium - MChD / The aim of the study is to compare the palliative efficacy of two saliva substitutes (Sinspeek and Xerostom) in patients during radiotherapy for cancer of the head and neck. This crossover randomised controlled clinical trial was carried out on twenty-five patients with malignant tumours of the head and neck, following four weeks of radiotherapy at tygerberg hospital. The benefit of saliva substitutes to ameliorate the effects of xerostomia is well established and proper advice and access to relevant preparations is essential. / South Africa
6

Development of a computerised sliding friction instrument and its use on oral mucosa and skin

Olsson, Håkan. January 1994 (has links)
Thesis (doctoral)--Lunds Universitet, Malmö, 1994. / Added t.p. with thesis statement inserted. Includes bibliographical references.
7

Development of a computerised sliding friction instrument and its use on oral mucosa and skin

Olsson, Håkan. January 1994 (has links)
Thesis (doctoral)--Lunds Universitet, Malmö, 1994. / Added t.p. with thesis statement inserted. Includes bibliographical references.
8

Hipossialia : sintomas, diagnóstico e possibilidades de tratamento

Rocha, Denise Pinheiro Falcão da 26 November 2010 (has links)
Tese (doutorado)—Universidade de Brasília, Faculdade de Ciências da Saúde, 2008. / Texto parcialmente liberado pelo autor. Conteúdo: Resumo, Sumário, Introdução, Objetivos, Justificativa, Materiais e Métodos e Resultados. / Submitted by Marília Freitas (marilia@bce.unb.br) on 2011-05-02T20:03:51Z No. of bitstreams: 1 2010_DenisePinheiroFalcaodeRocha_Parcial.pdf: 1854103 bytes, checksum: e2b98f26202adfca2387c6ef6d993938 (MD5) / Approved for entry into archive by Daniel Ribeiro(daniel@bce.unb.br) on 2011-05-21T01:36:08Z (GMT) No. of bitstreams: 1 2010_DenisePinheiroFalcaodeRocha_Parcial.pdf: 1854103 bytes, checksum: e2b98f26202adfca2387c6ef6d993938 (MD5) / Made available in DSpace on 2011-05-21T01:36:08Z (GMT). No. of bitstreams: 1 2010_DenisePinheiroFalcaodeRocha_Parcial.pdf: 1854103 bytes, checksum: e2b98f26202adfca2387c6ef6d993938 (MD5) Previous issue date: 2010-11 / Objetivo: Verificar a efetividade de novos recursos para o diagnóstico e tratamento da hipossialia e xerostomia. Materiais e Métodos: foram realizados delineamentos variados, de acordo com o objetivo específico de cada uma das pesquisas que foram desenvolvidas. Para tanto, alguns aspectos clínicos importantes como a abordagem dada à saliva no atendimento clínico de um grupo de periodontistas e a prevalência de sintomas decorrentes da redução do fluxo salivar em idosos sob uso e não uso de medicamentos foram avaliados. Para se obter dados mais detalhados sobre a efetividade das terapias a serem testadas, investigou-se uma metodologia de aferição da secreção salivar de glândulas menores do palato e da mucosa labial superior. Resultados: observou-se que os periodontistas não avaliam de forma rotineira parâmetros salivares de seus pacientes. Verificou-se também que idosos que fazem uso de medicação apresentam fluxo salivar menor quando comparados aos idosos não usuários de medicações. Dentre os sintomas comumente associados à redução de fluxo salivar, destacaram xerostomia, micção noturna e sensação de algo preso na garganta. O teste de Schirmer mostrou-se efetivo na avaliação da saliva de glândulas menores. Verificou-se que dentre as terapias avaliadas, o dispositivo GenNarino – Saliwell foi eficaz em aumentar a saliva total de repouso e de glândulas salivares menores do lábio superior e palato, enquanto que a terapia laser associada à eletroestimulação neuroelétrica transcutânea promoveu maior alívio da xerostomia. Conclusão: As terapias elétricas apresentaram resultados satisfatórios tanto para hipossialia, como para xerostomia. Contudo, há necessidade de se abordar o tema saliva de forma contextualizada clinicamente no processo de formação profissional, uma vez que os resultados mostraram que a hipossialia e a xerostomia afetam negativamente a vida dos indivíduos e que métodos eficazes de diagnóstico e tratamento estão disponíveis. _______________________________________________________________________________________ ABSTRACT / Objective: verify the effectiveness of new resources for the diagnosis and treatment of hyposialia and xerostomia. Materials and Methods: it was carried out various designs, according to the specific purpose of each of the surveys that were developed. To this end, some important clinical aspects such as the approach to clinical care in the saliva of a group of periodontist and the prevalence of symptoms resulting from reduced salivary flow in the elderly under use and non use of medication were evaluated. To obtain more detailed data on the effectiveness of therapies to be tested, it was investigated a method of measuring minor salivary glands of the palate and the upper lip mucosa. Results: Periodontists do not assess salivary parameters of their patients routinely. It was also found that elderly who make use of medication has less salivary flow rate when compared to non-users. Among the symptoms commonly associated with reduced salivary secretion, xerostomia stood out followed by nighttime urination and feeling of something stuck in throat. The Schirmer test was effective in the evaluation of minor salivary glands. It was found that the device GenNarino - Saliwell was effective in increasing unstipulated whole saliva, from minor salivary glands of the upper lip and palate, while laser therapy associated with transcutaneous eletric neuroestimulation, for xerostomia relief. Conclusion: The electrical therapies showed satisfactory results for both hipossialia as for xerostomia. However, there is need to address the issue saliva in clinical context during the graduating process, since the results showed that hyposialia and xerostomia affect negatively the individuals’ life and considering that effective methods of diagnosis and treatment are available.
9

Formulação de gel termossensível mucoadesivo contendo cloridrato de pilocarpina para tratamento de xerostomia

SILVA, Camila Maria Barros da 28 July 2017 (has links)
Submitted by Pedro Barros (pedro.silvabarros@ufpe.br) on 2018-09-13T22:13:19Z No. of bitstreams: 2 license_rdf: 811 bytes, checksum: e39d27027a6cc9cb039ad269a5db8e34 (MD5) DISSERTAÇÃO Camila Maria Barros da Silva.pdf: 3423150 bytes, checksum: 4c1ae60d5368ec7f7f8f1a85c6100e86 (MD5) / Approved for entry into archive by Alice Araujo (alice.caraujo@ufpe.br) on 2018-09-18T15:07:44Z (GMT) No. of bitstreams: 2 license_rdf: 811 bytes, checksum: e39d27027a6cc9cb039ad269a5db8e34 (MD5) DISSERTAÇÃO Camila Maria Barros da Silva.pdf: 3423150 bytes, checksum: 4c1ae60d5368ec7f7f8f1a85c6100e86 (MD5) / Made available in DSpace on 2018-09-18T15:07:45Z (GMT). No. of bitstreams: 2 license_rdf: 811 bytes, checksum: e39d27027a6cc9cb039ad269a5db8e34 (MD5) DISSERTAÇÃO Camila Maria Barros da Silva.pdf: 3423150 bytes, checksum: 4c1ae60d5368ec7f7f8f1a85c6100e86 (MD5) Previous issue date: 2017-07-28 / CAPES / O cloridrato de pilocarpina tem sido utilizado no tratamento da xerostomia, entretanto sua atuação sistêmica promove reações adversas indesejáveis. Tal problemática leva a necessidade da criação de formulações para a aplicação na mucosa bucal visando efeito local e diminuição da intensidade dos efeitos adversos. Assim, este trabalho objetivou o desenvolvimento de formulações termossensíveis utilizando Poloxamer 407 associado a polímeros naturais mucoadesivos para o carreamento do cloridrato de pilocarpina. Inicialmente foi realizada a caracterização das matérias primas por infravermelho (IV) e análise térmica. As formulações foram obtidas pela solubilização inicial dos polímeros naturais goma do cajueiro e goma karaya em água purificada e quitosana em solução de ácido acético a 1%. As concentrações utilizadas dos polímeros naturais foram de 0,25%, 0,5% e 1,0 % na proporção peso/volume (p/v). Posteriormente, o Poloxamer 407 foi adicionado à solução anterior na concentração de 18% (p/v) e mantida sob resfriamento (4°a 8°C) até completa solubilização do polímero. As formulações obtidas foram avaliadas quanto capacidade de transição solução-gel (sol-gel), temperatura e tempo de gelificação, viscosidade, módulo elástico e propriedades reológicas, além do perfil de liberação. As formulações de Poloxamer 407 18% contendo quitosana e goma do cajueiro em todas as concentrações não apresentaram propriedades de gelificação com o aumento de temperatura. Já as associadas a goma karaya apresentaram um incremento nas propriedades de gelificação com aumento da viscosidade. A formulação contendo goma karaya 1% apresentou maior viscosidade, menor tempo de transição sol-gel, assim como a maior capacidade mucoadesiva. Para avaliação do perfil de liberação, foram comparados o fármaco isolado, a formulação de Poloxamer 407 18% com pilocarpina e Poloxamer 407 18% + goma karaya 1% com pilocarpina e observou-se que a formulação contendo goma karaya 1% apresentou a liberação mais sustentada do fármaco. Diante disto, a utilização de polímeros naturais podem aumentar a capacidade geleificante de componentes já existentes no mercado, sendo a goma karaya um material promissor para a obtenção de novos sistemas mucoadesivos de liberação local e modificada. / Pilocarpine chloride has been used on treatment of xerostomia, however its systemic action promotes undesirable adverse events. Due to this problem it is necessary create formulation to be applied directly on buccal mucosa to produce local effect and reduce the intensity of adverse effects. So, this work aimed the development of thermosensitive formulation using poloxamer 407 associated to mucoadhesive natural polymers as carrier of pilocarpine chloride. First the characterization of raw materials was realized by infrared (IV) and thermal analysis. Formulations were obtained by initial solubilization of natural polymers cashew and karaya gums in purified water and chitosan in 1% acetic acid solution. The concentrations of the natural polymers used were 0.25, 0.5 and 1.0% in proportion weight/volume (w/v). After, the poloxamer 407 was added to previous solution in concentration of 18% (w/v) and maintained under cooling (4 to 8°C) until complete polymer solubilization. The formulations obtained were evaluated as to solution-gel (sol-gel) transition capacity, gelling temperature and time, elastic modulus and rheological properties. The gels with thermosensitive property were submitted to mucoadhesive force and release profile by dialysis method evaluation.Poloxamer 407 formulation 18% containing chitosan and cashew gum in all different concentrations did not presented gelling properties with temperature of increase. However, the formulation associated to karaya gum showed a increase in gelling properties with high viscosity. The 1% karaya gum formulation presented higher viscosity, shorter time of sol-gel transition, as well as greater mucoadhesive capacity. To release profile evaluation were compared the isolated drug, 18% poloxamer 407 formulation with pilocarpine and poloxamer 407 18% + karaya gum 1% with pilocarpine, which was observed that formulation containing 1% karaya gum showed more sustained release of drug. On these, the use of natural polymers can increase the gelling capacity of components on the market and karaya gum showed as promissor material to obtaining of new mucoadhesive systems to modified and local release.
10

Condição periodontal e hipertensão arterial em pacientes obesos mórbidos antes e após a cirurgia bariátrica: estudo de coorte prospectivo / Periodontal condition and arterial hypertension in morbidly obese patients before and after bariatric surgery: prospective cohort study

Guzmán Tavarez, Andrés Dario 11 September 2017 (has links)
A hipertensão e a obesidade têm sido descritas como graves problemas de saúde pública, tendo uma prevalência de obesidade no Brasil de 20%. Além de causar problemas sistêmicos, a hipertensão e a obesidade podem afetar as condições bucais. Diante disso, o objetivo deste estudo foi identificar doença periodontal em indivíduos obesos hipertensos e não hipertensos, no pré e pós-cirurgia bariátrica (CB), com seguimento de 12 meses. A amostra foi composta por 70 indivíduos distribuídos em dois grupos: grupo obeso com hipertensão (G01=35) e grupo obeso sem hipertensão (G02=35), ambos os grupos foram avaliados no pré e pós cirurgia bariátrica. A avaliação antropométrica dos indivíduos foi realizada através do IMC e circunferência da cintura. O sangramento a sondagem foi realizado por meio do índice de sangramento gengival, da profundidade de sondagem e do nível de inserção clínica e recessão gengival. Foi analisado o fluxo salivar não estimulado e estimulado para mensurar o volume (mL/min). Foram adotados os testes de Kruskal- Wallis, Mann-Whitney, Qui-quadrado e Exato de Fisher (p<0,05). O gênero feminino foi o mais prevalente na amostra avaliada, em ambos os grupos avaliados (G01=85,3%; G02=80%). O modelo ajustado utilizando regressão logística mostrou que apenas a idade (p<0,0001) e a recessão gengival (p=0,0320) foram determinantes na diferença entre os hipertensos e não hipertensos. O período de 12 meses (p=0,913), sexo (p=0,608), IMC (p=0,412), RCQ (p=0,577), profundidade média de bolsa (p=0,114), recessão máxima (p=0,236), escore de recessão (p=0,319), nível de inserção periodontal (p=0,486), escore de nível de inserção periodontal (p=0,074), cálculo (p=0,745), sangramento (p=0,172), fluxo salivar não estimulado (p=0,980), fluxo salivar estimulado (p=0,964) e escolaridade (p=0,448), não foram significativos. Concluiu-se que indivíduos obesos mórbidos com hipertensão arterial apresentam pior condição periodontal e que a CB não interferiu negativamente na saúde periodontal, dentro de cada grupo. / Hypertension and obesity have been described as serious public health problems as they have increased in alarming proportions both globally and nationally, with a prevalence of obesity in Brazil of 20%. In addition to causing systemic problems, hypertension and obesity can affect oral conditions. Therefore, the objective of this study was to identify periodontal disease in hypertensive and non-hypertensive obese individuals, before and after bariatric surgery (CB), with a follow-up of 12 months. The sample consisted of 70 individuals divided into two groups: obese group with hypertension (G01 = 35) and obese group without hypertension (G02 = 35), both groups were evaluated before and after bariatric surgery. The anthropometric evaluation of the individuals was performed through BMI and waist circumference. Bleeding was performed by means of gingival bleeding index, depth of probing and level of clinical insertion and gingival recession. The non-stimulated and stimulated salivary flow was analyzed to measure the volume (mL / min). The Kruskal-Wallis, Mann-Whitney, Chi-square and Fisher Exact tests were used (p <0.05). The female gender was the most prevalent in the sample evaluated, in both groups (G01 = 85.3%, G02 = 80%). The adjusted model using logistic regression showed that only age (p <0.0001) and gingival recession (p = 0.0320) were determinants of the difference between hypertensive and non-hypertensive individuals. (P = 0.368), mean BMI (p = 0,412), BMI (p = 0,412), WHR (p = 0.577), mean bursal depth (p = 0,114), maximum recession (P = 0.745), bleeding (p = 0,172), non-stimulated salivary flow (p = 0,319), periodontal insertion level (p = 0,419), periodontal insertion level P = 0.980), stimulated salivary flow (p = 0.964) and schooling (p = 0.448), were not significant. It was concluded that morbidly obese individuals with arterial hypertension present worse periodontal conditions and that CB did not negatively affect periodontal health within each group.

Page generated in 0.7008 seconds