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  • About
  • The Global ETD Search service is a free service for researchers to find electronic theses and dissertations. This service is provided by the Networked Digital Library of Theses and Dissertations.
    Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
1

Assessing confounding by motivated testing when using the serologic testing algorithm for recent HIV seroconversion (STARHS) to estimate seroincidence among clinical testing populations /

White, Edward William. January 2006 (has links)
Thesis (Ph. D.)--University of Washington, 2006. / Vita. Includes bibliographical references (leaves 47-55).
2

Taiwanese nurses' knowledge, attitudes, and intentions about caring for patients who are HIV positive

Tsai, Yun-Fang. January 1993 (has links)
Thesis (M.S.)--University of Wisconsin-Madison, 1993. / Typescript. eContent provider-neutral record in process. Description based on print version record. Includes bibliographical references (leaves 41-44).
3

"Estudo da distribuição de doadores reativos para a doença de Chagas no Hemocentro de Ribeirão Preto, SP" / Seropositivity for Chagas’ disease among blood donators in the Regional Blood Bank of Ribeirão Preto, State of São Paulo, Brazil.

Soussumi, Léa Mara Tosi 27 February 2004 (has links)
SOUSSUMI, LMT. Estudo da distribuição de doadores reativos para a doença de Chagas no Hemocentro de Ribeirão Preto, SP. 2004. 106f. Dissertação (Mestrado) – Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, 2004. Este estudo, de que participaram 25.891 doadores de sangue que compareceram pela primeira vez ao Hemocentro de Ribeirão Preto, de junho de 1996 a junho de 2001, teve por objetivos: 1) estudar a freqüência de resultados sorológicos positivos e inconclusivos na triagem sorológica para a doença de Chagas; 2) estimar a prevalência de doadores infectados com T. cruzi entre os doadores acima definidos, através da aplicação de testes confirmatórios; e 3) caracterizar os doadores infectados segundo algumas variáveis de interesse epidemiológico. Foram levantados dados registrados no sistema informatizado do Hemocentro de Ribeirão Preto, coletando-se informações referentes ao doador, ao tipo de doação e ao resultado de teste de triagem para doença de Chagas. Foram estudados ainda os resultados dos testes confirmatórios, além de algumas variáveis de interesse epidemiológico, como idade, local de procedência e de nascimento, tipo da doação e motivo da doação. A população foi composta majoritariamente por homens (83,6%) e indivíduos de 26 a 45 anos de idade (64,1%), em sua maioria residente no Estado de São Paulo (88,2%). Predominaram as doações vinculadas (85,4%), tendo como principal motivação a solicitação de amigos ou razões familiares. A triagem sorológica foi realizada com a aplicação de dois testes (ELISA e IHA), com 244 resultados positivos e 386 inconclusivos; destes, 236 foram submetidos a testes confirmatórios, dos quais 28 (11.9%) tiveram resultado positivo confirmado. Os 272 com resultado positivo correspondem um valor de prevalência de 1,1% (IC95%: 0,9 – 1,2). A situação sorológica dos demais candidatos foi classificada em: negativa (n=25.521; 98,6%), indeterminada (n=14; 0,1%) e desconhecida (n=84; 0,3%). Do grupo dos doadores com situação sorológica desconhecida, 80 não compareceram ao retorno e 4 apresentaram problemas relacionados às amostras de sangue. A grande maioria dos doadores infectados, apesar de residir na região administrativa da cidade de Ribeirão Preto, no Estado de São Paulo, migrou de outras Unidades Federadas, onde era alta a prevalência da doença de Chagas no passado. Esse fato ficou evidenciado pela elevação progressiva e constante da prevalência da doença, intimamente relacionada com a idade mais avançada dos procedentes de Minas Gerais e, especialmente, de São Paulo. Os baixos percentuais de soropositividade entre os jovens nascidos em São Paulo evidenciam os avanços obtidos no controle da doença neste estado, que antecederam aqueles realizados em outras UFs do Brasil. Entretanto, os resultados deste estudo mostraram que ainda existem doadores jovens infectados procedentes de áreas onde o Programa Nacional de Controle da Doença de Chagas tem sofrido problemas crônicos de continuidade. / SOUSSUMI, LMT. Seropositivity for Chagas’ disease among blood donators in the Regional Blood Bank of Ribeirão Preto, State of São Paulo, Brazil. 2004. 106f. Dissertação (Mestrado) – Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, 2004. This study involved 25.891 subjects who donated blood for the first time at the Blood Center of Ribeirao Preto, State of Sao Paulo, Brazil, from June 1996 to June 2001. The investigation had the following objectives: 1) to study the frequency of positive and indeterminate results for Chagas’ disease in screening tests; 2) to estimate the prevalence of blood donors infected with Trypanosoma cruzi through confirmatory assays; and 3) to describe the infected individuals according to some variables of epidemiological interest. Information was obtained from the computerized system of the Blood Center, by collecting data about blood donors, type of donation and results of screening and confirmatory tests for Chagas´ disease. In addition, some variables of epidemiological interest, such as age, origin, place of birth, type of donation and motive for donation were also studied. The population was mostly composed of men (83,6%) and individuals from 26 to 45 years of age (64,1%), most of them resident in the State of Sao Paulo (88,2%). Family reasons and friends’ requests were the main determinants for blood donation (85,4%). The serological screening was carried out by applying two tests (ELISA and IHA), resulting 244 positive and 386 inconclusive. Of the latter group, 386 inconclusive results, 236 were submitted to confirmatory assays, 28 of whom (11.9%) were found to be positive. In the total, there were 272 positive results, corresponding to a prevalence rate of 1,1% (CI95%: 0,9 – 1,2). Regarding the serological situation, the other subjects were classified as: negative (n=25.521; 98,6%), indeterminate (n=14; 0,1%) and unknown (n=84, 0,3%). Of this last group, 80 did not attend to the return visit and 4 presented problems related to blood samples. Despite living in the area around Ribeirao Preto, the great majority of infected donors migrated from other States, where the prevalence of Chagas´ disease was high in the past. This fact was evidenced by the progressive and constant elevation of prevalence rates, closely related to older ages among donors coming from the State of Minas Gerais and, especially, from the State of Sao Paulo. The low rate of positive results among young individuals born in Sao Paulo confirms the improvements obtained in the control of the disease in this State, that preceded those accomplished in other parts of Brazil. However, this study still shows the existence of infected young blood donors, originally living in areas where the National Program for Control of Chagas’ Disease has been suffering chronic operational problems.
4

"Estudo da distribuição de doadores reativos para a doença de Chagas no Hemocentro de Ribeirão Preto, SP" / Seropositivity for Chagas’ disease among blood donators in the Regional Blood Bank of Ribeirão Preto, State of São Paulo, Brazil.

Léa Mara Tosi Soussumi 27 February 2004 (has links)
SOUSSUMI, LMT. Estudo da distribuição de doadores reativos para a doença de Chagas no Hemocentro de Ribeirão Preto, SP. 2004. 106f. Dissertação (Mestrado) – Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, 2004. Este estudo, de que participaram 25.891 doadores de sangue que compareceram pela primeira vez ao Hemocentro de Ribeirão Preto, de junho de 1996 a junho de 2001, teve por objetivos: 1) estudar a freqüência de resultados sorológicos positivos e inconclusivos na triagem sorológica para a doença de Chagas; 2) estimar a prevalência de doadores infectados com T. cruzi entre os doadores acima definidos, através da aplicação de testes confirmatórios; e 3) caracterizar os doadores infectados segundo algumas variáveis de interesse epidemiológico. Foram levantados dados registrados no sistema informatizado do Hemocentro de Ribeirão Preto, coletando-se informações referentes ao doador, ao tipo de doação e ao resultado de teste de triagem para doença de Chagas. Foram estudados ainda os resultados dos testes confirmatórios, além de algumas variáveis de interesse epidemiológico, como idade, local de procedência e de nascimento, tipo da doação e motivo da doação. A população foi composta majoritariamente por homens (83,6%) e indivíduos de 26 a 45 anos de idade (64,1%), em sua maioria residente no Estado de São Paulo (88,2%). Predominaram as doações vinculadas (85,4%), tendo como principal motivação a solicitação de amigos ou razões familiares. A triagem sorológica foi realizada com a aplicação de dois testes (ELISA e IHA), com 244 resultados positivos e 386 inconclusivos; destes, 236 foram submetidos a testes confirmatórios, dos quais 28 (11.9%) tiveram resultado positivo confirmado. Os 272 com resultado positivo correspondem um valor de prevalência de 1,1% (IC95%: 0,9 – 1,2). A situação sorológica dos demais candidatos foi classificada em: negativa (n=25.521; 98,6%), indeterminada (n=14; 0,1%) e desconhecida (n=84; 0,3%). Do grupo dos doadores com situação sorológica desconhecida, 80 não compareceram ao retorno e 4 apresentaram problemas relacionados às amostras de sangue. A grande maioria dos doadores infectados, apesar de residir na região administrativa da cidade de Ribeirão Preto, no Estado de São Paulo, migrou de outras Unidades Federadas, onde era alta a prevalência da doença de Chagas no passado. Esse fato ficou evidenciado pela elevação progressiva e constante da prevalência da doença, intimamente relacionada com a idade mais avançada dos procedentes de Minas Gerais e, especialmente, de São Paulo. Os baixos percentuais de soropositividade entre os jovens nascidos em São Paulo evidenciam os avanços obtidos no controle da doença neste estado, que antecederam aqueles realizados em outras UFs do Brasil. Entretanto, os resultados deste estudo mostraram que ainda existem doadores jovens infectados procedentes de áreas onde o Programa Nacional de Controle da Doença de Chagas tem sofrido problemas crônicos de continuidade. / SOUSSUMI, LMT. Seropositivity for Chagas’ disease among blood donators in the Regional Blood Bank of Ribeirão Preto, State of São Paulo, Brazil. 2004. 106f. Dissertação (Mestrado) – Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, 2004. This study involved 25.891 subjects who donated blood for the first time at the Blood Center of Ribeirao Preto, State of Sao Paulo, Brazil, from June 1996 to June 2001. The investigation had the following objectives: 1) to study the frequency of positive and indeterminate results for Chagas’ disease in screening tests; 2) to estimate the prevalence of blood donors infected with Trypanosoma cruzi through confirmatory assays; and 3) to describe the infected individuals according to some variables of epidemiological interest. Information was obtained from the computerized system of the Blood Center, by collecting data about blood donors, type of donation and results of screening and confirmatory tests for Chagas´ disease. In addition, some variables of epidemiological interest, such as age, origin, place of birth, type of donation and motive for donation were also studied. The population was mostly composed of men (83,6%) and individuals from 26 to 45 years of age (64,1%), most of them resident in the State of Sao Paulo (88,2%). Family reasons and friends’ requests were the main determinants for blood donation (85,4%). The serological screening was carried out by applying two tests (ELISA and IHA), resulting 244 positive and 386 inconclusive. Of the latter group, 386 inconclusive results, 236 were submitted to confirmatory assays, 28 of whom (11.9%) were found to be positive. In the total, there were 272 positive results, corresponding to a prevalence rate of 1,1% (CI95%: 0,9 – 1,2). Regarding the serological situation, the other subjects were classified as: negative (n=25.521; 98,6%), indeterminate (n=14; 0,1%) and unknown (n=84, 0,3%). Of this last group, 80 did not attend to the return visit and 4 presented problems related to blood samples. Despite living in the area around Ribeirao Preto, the great majority of infected donors migrated from other States, where the prevalence of Chagas´ disease was high in the past. This fact was evidenced by the progressive and constant elevation of prevalence rates, closely related to older ages among donors coming from the State of Minas Gerais and, especially, from the State of Sao Paulo. The low rate of positive results among young individuals born in Sao Paulo confirms the improvements obtained in the control of the disease in this State, that preceded those accomplished in other parts of Brazil. However, this study still shows the existence of infected young blood donors, originally living in areas where the National Program for Control of Chagas’ Disease has been suffering chronic operational problems.
5

The Lived Experience of Women of Mexican Heritage with HIV/AIDS

Dominguez, Linda Maria, 1950- January 1996 (has links)
No description available.
6

Convivendo com HIV/AIDS : fatores que influenciam na qualidade de vida e condição de saúde bucal /

Soares, Gabriella Barreto. January 2013 (has links)
Orientador: Artênio José Ísper Garbin / Co-orientador: Cléa Adas Saliba Garbin / Banca: Renato Moreira Arcieri / Banca: Patricia Elaine Gonçalves / Resumo: O conhecimento dos fatores que influenciam a qualidade de vida e condição de saúde bucal das pessoas que vivem com HIV/AIDS é importante para o planejamento das ações nos serviços de saúde. O presente estudo teve como objetivo verificar os fatores que influenciam na qualidade de vida e na condição de saúde bucal das pessoas que vivem com HIV/AIDS. Foi realizado um estudo transversal com abordagem quantitativa, desenvolvido em 2012, com uma amostra de 177 HIV+ que fazem acompanhamento no Centro de referência DST/AIDS, de Vitória, Espírito Santo. Utilizou-se um questionário estruturado para avaliar as condições sociodemográficas, aspectos relacionados ao HIV, hábitos, utilização e satisfação com serviço de saúde. A qualidade de vida foi analisada por meio do instrumento HAT-QoL, com 42 itens divididos em nove domínios: Atividade Geral, Atividade Sexual, Preocupações com sigilo, Preocupação com a Saúde, Preocupação Financeira, Conscientização sobre o HIV, Satisfação com a Vida, Questões relativas à medicação e Confiança no médico. Os dados de saúde bucal foram coletados por meio do índice de CPO-D, uso e necessidade de prótese e Índice Periodontal Comunitário, de acordo com os critérios propostos pela Organização Mundial de Saúde, por um pesquisador calibrado (kappa>0,81). Foram realizadas análises descritivas, bivariadas, regressão linear e logística múltipla, considerando nível de significância de 0,05 e intervalo de confiança de 95%. Os dados foram avaliados no programa SPSS, versão 17.0. Na análise da qualidade de vida o domínio do HAT-QoL com menor média foi Preocupação financeira (39,4), seguido de Preocupação com sigilo (43,2), Atividades sexuais (55,2) e Preocupação com a saúde (62,88). Houve associação... / Abstract: The importance to know the factors that influence the quality of life and oral health of individuals with HIV/AIDS is focused on the planning of actions on health services. The present study had the aim to verify the factors that influence the quality of life and oral health of individuals with HIV/AIDS. It was realized a cross-sectional study with quantitative approaching, developed in 2012 with 177 HIV+ that were attended on the AIDS Reference Public Centre, in Vitória, Espírito Santo State, Brazil. It was used a structured questionnaire to evaluate social and demographic status, aspects related to HIV, habits, the use and satisfaction with health service. The quality of life was analyzed using the HAT-QoL instrument with 43 items divided in 9 domains: General Activity, Sexual Life, Worries with Secrecy, Worries with Health, Financial Worries, Awareness about HIV, Life Satisfaction, Questions related to medicine and trust in the doctor. The oral health data were collected using the DMF-T Index, the use and necessity of prosthesis and Periodontal Index, according to World Health Organization's criteria, performed by a trained researcher (Kappa>0.081). Descriptive and bivariate analysis, linear and multiple logistic regression models were applied, adopting 0.05 of significance level. Data were evaluated by SPSS software, version 17.0. About quality of life, the domain of HAT-QoL questionnaire that showed the lowest average was financial worries (39.4), followed by worries with secrecy (43.2), sexual life (55.2) and worries with health (62.88). There was association between the worst score o quality of life and the follow variables: have no registered work (p<0.001), to be black or mixed (p=0.045), to consume alcoholic drinks (p=0.041), not to use antiretroviral therapy... / Mestre
7

Impact of immunosuppression on the incidence and clearance of human papillomavirus in HIV-infected women in Alabama

Bhatta, Madhav P. January 2007 (has links) (PDF)
Thesis (Ph. D.)--University of Alabama at Birmingham, 2007. / Title from first page of PDF file (viewed Oct. 13, 2008). Includes bibliographical references.
8

Prevalence and susceptibility of Cryptococcus neoformans to fluconazole in HIV patients in Kenya

Mdodo, Rennatus M. January 2010 (has links) (PDF)
Thesis (D.P.H.)--University of Alabama at Birmingham, 2010. / Title from PDF title page (viewed on July 1, 2010). Includes bibliographical references.
9

Des représentations sociales du VIH/sida à la construction d'une identité séropositive : analyse de discours en pays Moba (Nord-Togo) / From social representations of HIV/aids in Moba's area to the seropositive identity building : the speech analysis in North-Togo

Kanati, Lardja 16 December 2011 (has links)
La recherche concerne les représentations sociales du VIH/sida, en pays Moba (Nord Togo) telles qu’elles sont socialement et culturellement perçues, tant par les personnes vivant au quotidien avec le VIH/sida que par celles qui ne sont pas atteintes. Une revue de la littérature a mis en évidence l’évolution des connaissances, croyances, attitudes, inquiétudes et défenses au regard de l’évolution du VIH/sida à travers le monde. Elle a permis d’identifier les éléments constitutifs des représentations sociales du VIH/sida en les abordant à travers le prisme du modèle contagionniste, des théories profanes, de l’action raisonnée et du comportement planifié. On a exploré aussi les théories explicatives (du stigmate, des préjugés et des discriminations) et celles dites des «peurs liminales». Des travaux empiriques ont été menés en pays Moba, au Nord-Togo. Les objectifs ont été d’analyser les composantes des discours populaires/profanes des personnes non infectées et des personnes infectées afin de mettre en évidence les phénomènes cognitifs induits par les représentations sociales de la maladie qui contribuent à la construction d'une identité séropositive. Méthode 410 personnes, âgées de 18 à 56 ans, ont été interrogées : 376 personnes non infectées (dont 269 prises de manière aléatoire), 7 agents de l’Association Vivre dans l’Espérance prenant en charge des personnes vivant avec le VIH, 34 personnes infectées par le VIH/sida. Une analyse quantitative des données a été menée à l'aide du logiciel SPSS (Statistical Social Sciences Package); traitement des tests de khi-deux de Pearson. Une analyse de contenu sociolinguistique s’est appliquée aux différents discours produits. Elle s'est faite en identifiant des catégories clés. Pour effectuer une procédure de contrôle, nous avons eu recours à la méthode des jurés qui nous a permis de valider les catégories identifiées par deux enseignants de l'Université de Kara originaires du pays Moba comme nous.Résultats, discussion et conclusion Les représentations sociales du VIH/sida en pays Moba s’élaborent et se structurent sous l’influence de processus socioculturels qui demeurent préjudiciables pour les personnes atteintes du VIH. Si les personnes non infectées continuent de considérer le sida comme une maladie grave, mortelle ou encore comme une maladie «honteuse» parce qu’elle est liée au sexe, les personnes infectées ne semblent pas s’auto-stigmatiser comme des «personnes dangereuses» et se décrivent plutôt comme des patients atteints d’une maladie chronique, au même titre que ceux qui sont victimes du paludisme. Elles précisent que la prise en charge médicale et psycho-sociale a produit un changement (décrit comme «positif») dans la perception de la maladie et de celui qui en est porteur. Les attitudes à leur endroit seraient et resteraient malgré tout «hostiles». Ce facteur serait à l’origine de «souffrances» de ces personnes et de la mise en œuvre au quotidien de stratégies permettant de faire face à leur mal. Une véritable identité séropositive semble se construire autour des déterminants comportementaux qui portent sur la prévention d’une éventuelle double infection, le mariage entre séropositifs, le maintien de l'exercice d'un métier, le renoncement aux activités sexuelles, la participation à des rituels spécifiques de deuil, les témoignages à visage découvert, le maintien du non-dit et la politique du secret quant à leur séropositivité. / The social representations of HIV/AIDS such as they are socially and culturally perceived and the strategies updated in the speech of the people living at the daily with HIV/AIDS in Moba's area were explored. A significant review of the literature tried to highlight the evolution of knowledge, beliefs, attitudes, concerns and defenses in comparison with the international social events and to identify the components of the social representations of HIV/AIDS by approaching them through the prism of the model contagionnist, the profane theories, the reasoned action and the planned behavior, as well as the explanatory theories (of the mark, the prejudices and discrimination) and those of the liminal fears. Empric work was undertaken in Moba’s area, in North-Togo. The objectives were to analyze the components of the common/profanes speeches of uninfected and infected people in order to highlight the cognitive phenomena induced by the social representations of the disease which contribute to the construction of an identity of HIV-positive individual. In all, 410 old people of 18 with more than 56 years including/understanding: 376 uninfected people including 269 catches in a random way and 7 agents of Association Food in the Hope dealing with people living with the HIV and 34 people infected by HIV/AIDS. A sociolinguistic analysis of contents applied to the various produced speeches. It was done by identifying key categories as well as verbatim while measuring their importance. The use of SPSS software (Statistical Social Package for the Sciences) allowed to classify the speeches in order to emphasize recurring. To carry out a check procedure, we had recourseto the method of sworn which enabled us to validate the dcatégories identified by two teachers of the University of Kara originating in the Moba’s area like us. The social representations of HIV/AIDS in Moba’s area are worked out and structured under the influence of processes socioculturels which remain prejudicial for the people reached of the HIV. If the not infected people continue to regard the AIDS as a serious illness, mortal or a venereal disease because it is related to the sex, the infected people do not seem car-to stigmatize themselves like “dangerous people” and describe themselves rather like patients reached of a chronic disease, as well as those which are victims of malaria. They recognize that the medical and psychosocial assumption of responsibility produced a change (positive) in the perception of the disease and that which of it is carrying. The attitudes at their place would be and remain in spite of very hostile. This factor would be at the origin of the sufferings of these people and the implementation to the daily living strategies to face their evil. A true seropositive identity seems to be built around the behavioral determinants which relate to the prevention of the double infection, the marriage between hiv-positive individuals, the maintenance of the exercise of a trade, the renouncement of the sexual activities, the ritual specific ones of mourning, testimonys with discovered face, the maintenance of the unvoiced comment and the policy of the secrecy as for their seropositivity.
10

Rickettsia sp. em roedores e marsupiais silvestres do Rio Grande do Norte, Brasil / Rickettsia sp. in wild rodents and marsupials of Rio Grande do Norte, Brazil

Paiva, Kaliane Alessandra Rodrigues de 22 February 2016 (has links)
Submitted by Socorro Pontes (socorrop@ufersa.edu.br) on 2017-03-14T14:27:57Z No. of bitstreams: 1 KalianeARP_DISSERT.pdf: 1933642 bytes, checksum: d81d7572738a12680036b924e51703d5 (MD5) / Made available in DSpace on 2017-03-14T14:27:57Z (GMT). No. of bitstreams: 1 KalianeARP_DISSERT.pdf: 1933642 bytes, checksum: d81d7572738a12680036b924e51703d5 (MD5) Previous issue date: 2016-02-22 / Coordenação de Aperfeiçoamento de Pessoal de Nível Superior / Rickettsia are pathogens with zoonotic potential transmitted by wild and domestic animals, where the occurrence of infections by Rickettsia spp. It happens among populations of wild rodents and marsupials, which has a significant share in the maintenance cycle of these microorganisms in the wild environment. Thus, this study aimed to record the occurrence of Rickettsia sp. in wild rodents and marsupials in the Rio Grande do Norte semi-arid. The work consisted in a field research with wild rodents and marsupials, with data expressed in simple frequency and percentage using IBM SPSS (Armonk, NY: IBM Corp.), version 22.0. Were captured in Sherman and Tomahawk traps, 02 Thrichomys, 03 Wiedomys, 30 Gracilinanus agilis and 06 Monodelphis domestica, which were collected by venipuncture of julgular vein, 36 blood samples of marsupials and 05 of rodents. These were collected 64 Amblyomma auricularium, 07 Amblyomma parvum and 12 Amblyomma sp. Were obtained by centrifugation 36 samples of sera marsupials and 05 rodents and analyzed using Immunofluorescence Assay (IFA). All copies of A. auricularium, Amblyomma sp. and A. parvum were macerated and submitted to DNA extraction and amplification by Polymerase Chain Reaction (PCR) directed to a fragment of gltA and ompA rickettsial genes. Of serum samples obtained from wild rodents and marsupials blood and tested in IFA showed seropositivity for Rickettsia amblyommii, 6.7% G. agilis, 83.3% M. domestica and 50% Thrichomys. Eight samples of A. auricularium were positive for genes in R. amblyommii fragment analysis gltA (350 bp) and ompA (587 bp) with 100% similarity to Candidatus R. amblyommii Bahia and AaPE strain, corresponding to a low circulation agent from the vectors and high among the population of M. domestica. This research records for the first time the occurrence of R. amblyommii in marsupial species G. agilis and M. domestica belonging to Didelphidae family and Echimyidae family rodents Thrichomys genre, in the semiarid region of Rio Grande do Norte, Brazil / Rickettsia são patógenos com potencial zoonótico transmitidos por animais silvestres e domésticos, onde a ocorrência de infecções por Rickettsia spp. acontece entre populações de roedores e marsupiais silvestres, os quais tem relevante participação na manutenção do ciclo desses microrganismos no ambiente silvestre. Desta forma, esse estudo objetivou registrar a ocorrência de Rickettsia sp. em roedores e marsupiais silvestres no semiárido do Rio Grande do Norte. O trabalho consistiu em uma pesquisa de campo, com roedores e marsupiais silvestres, com os dados expressos em frequência simples e porcentagem através do programa estatístico IBM SPSS (Armonk, NY: IBM Corp.), versão 22.0. Foram capturados nas armadilhas Sherman e Tomahawk, 02 Thrichomys, 03 Wiedomys, 30 Gracilinanus agilis e 06 Monodelphis domestica, dos quais foram coletados por venopunção da veia julgular, 36 amostras de sangue de marsupiais e 05 de roedores. Destes foram coletados 64 Amblyomma auricularium, 07 Amblyomma parvum e 12 Amblyomma sp. Foram obtidas por centrifugação 36 amostras de soros de marsupiais e 05 de roedores e analisadas utilizando a Reação de Imunofluorescência Indireta (RIFI). Todos os exemplares de A. auricularium, Amblyomma sp. e A. parvum foram macerados e submetidos a extração de DNA e amplificação através da Reação em Cadeia da Polimerase (PCR) direcionados para um fragmento dos genes gltA e ompA rickettsial. Das amostras de soro obtidas do sangue de roedores e marsupiais silvestres e testadas na RIFI, apresentaram soropositividade para Rickettsia amblyommii, 6,7% de G. agilis, 83,3% M. domestica e 50% Thrichomys. Oito exemplares de A. auricularium estavam positivos para R. amblyommii na análise de fragmentos dos genes gltA (350 pb) e ompA (587 pb), com 100% de similaridade com Candidatus R. amblyommii estirpe Bahia e AaPE, correspondendo a uma baixa circulação do agente dentre os vetores e elevada entre a população de M. domestica. Esta pesquisa registra pela primeira vez a ocorrência de R. amblyommii em marsupiais das espécies G. agilis e M. domestica pertencentes a família Didelphidae e roedores da família Echimyidae do gênero Thrichomys, no semiárido do Rio Grande do Norte, Brasil / 2017-03-13

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