This thesis describes the research I have done, and partly will do, during my time as a PhD student in the laboratory of Applied Optics at Linköping University. Due to circumstances beyond the scope of this book, this incorporates three quite different projects. The first two, involving gas sensing and measuring on paper with ellipsometry, have been discontinued, whereas the third one, measuring fluorescence with a computer screen and web camera, is in full progress and will be until I complete my studies. Thus the purpose of this work also has several aspects. Partly, it describes performed research and its results, as well as theoretical background. On the other hand, it provides practical and theoretical background necessary for future work. While the three projects are truly quite different, each of them has certain things in common with each of the other. This is certainly also true for the necessary theory. Two of them involve spectroscopic ellipsometry, for example, while another pair needs knowledge of color theory, etc. This makes it impossible to separate the projects, despite of their differences. Hopefully, these links between the different projects, connecting the different chapters, will make this work whole and consistent in its own way. / <p>Report code: LiU-TEK-LIC-200 4-19. On the day of the public defence the status of article I was: In press and the status of article III was: Manuscript and has a new title. The old title was Computer screen photo-assisted spectroscopic fluorimetry.</p>

京都大学 / 新制・論文博士 / 博士(農学) / 乙第13520号 / 論農博第2908号 / 新制||農||1096(附属図書館) / 学位論文||R4||N5420(農学部図書室) / 京都府立医科大学 / (主査)教授 中﨑 鉄也, 教授 土井 元章, 教授 及川 彰, 准教授 田中 朋之 / 学位規則第4条第2項該当 / Doctor of Agricultural Science / Kyoto University / DGAM

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Any center planning to install a Gamma Knife radiosurgery unit has to provide for an efficient shielding of the treatment room, to protect the patient, the staff and the public, against undesired radiation. The shielding barrier design is controlled by national and international recommendations; the reference documents for gamma ray radiotherapy facilities are the National Council on Radiation Protection and Measurements (NCRP) reports 49 and 151. However, some facts highlighted in this thesis point out that NCRP methods are ill-adapted to the Gamma Knife. Spectroscopic measurements were performed around the Gamma Knife with a Germanium detector. They revealed that the radiation field contains few high energy photons, is highly anisotropic, and that the leakage level is much lower than the NCRP estimation. These observations led to the development of a new approach to determine the necessary shielding, based on the actual and directly measurable radiation field around the unit. This method would reduce the shielding oversizing induced by the unsuitability of the NCRP recommendations for the Gamma Knife.