Understanding vocal fold mechanics is an integral part of voice research and synthetic vocal fold models are an essential tool in characterizing vocal fold mechanics. These models contain multiple layers with varying stiffness, much like human vocal folds. The purpose of this thesis is to improve the current models and modeling techniques, as well as investigate the impact of asymmetry on model vibration. A new design for an MRI-based model is detailed. This model has a more realistic geometry than the simplified models and mimics some of the vibratory characteristics observed in human vocal folds. The MRI-based model was used to investigate left-right stiffness asymmetry in multiple layers of the model. A zipper-like motion was observed during vibration of the MRI-based models. A phase shift was present in the asymmetric models, with the less stiff side leading the stiffer side. A new expendable mold fabrication process is described. This new process provides more freedom in designing vocal fold models and experiments. Additionally, the new process enables fabrication of models without the use of release agent, a factor which has, in the past, adversely impacted manufacturing yield and prohibited the incorporation of certain biological materials into the synthetic models. The new process also allows for more convenient geometry variation than what has previously been feasible. Finally, the new process was used to investigate cover layer geometry variation and asymmetry in a simplified model. Cover layer thickness was found to be a significant factor in governing the motion of the vocal fold model. Anterior-posterior asymmetry was found to induce the same zipper-like motion observed in the MRI-based models.

A review of current variable-stiffness actuators reveals a need for more simple, cost effective, and lightweight designs that can be easily incorporated into a variety of human-interactive robot platforms. This thesis considers the potential use of compliant mechanisms to improve the performance of variable-stiffness actuators. The advantages and disadvantages of various concepts using compliant mechanisms are outlined, along with ideas for further exploration. A new variable-stiffness actuator that uses a compliant flexure as the elastic element has been modeled, built, and tested. This new design involves a variable stiffness joint that makes use of a novel variable transmission. A prototype has been built and tested to verify agreement with the model which shows a reasonable range of stiffness and good repeatability. Ideas for further exploration are identified.

Heat therapy may be an alternative or adjunct intervention to exercise training for improving cardiovascular function and health. However, its prescription must be refined in order to overcome the feasibility and tolerability issues associated with current whole-body heating modes. There is substantial evidence to support the beneficial effects of high doses (e.g., frequency, duration, and intensity) of heating typically achieved using whole-body modes, but there is limited knowledge on whether lower doses of heating administered through local hot water immersion of the limbs can still have an impact on vascular function. All studies were conducted in heathy young men and women. In the first study, we found that regardless of whether local heating was applied to the lower limbs up to the ankles or knees, upper limb endothelial function and lower limb arterial stiffness improved acutely. In the second study, we proceeded to prescribe ankle-level heating in a chronic intervention and compared its effects to that of moderate-intensity cycling exercise training. We observed no changes in endothelial function, but decreases in central arterial stiffness and increases in cardiorespiratory fitness in those who performed heat therapy and exercise training combined with heat therapy. In the third study, we evaluated the ability of acute vascular function responses to predict chronic vascular function responses with heating and exercise interventions, and found significant positive associations between the acute and chronic responses for absolute and relative brachial artery flow-mediated dilation and femoral-foot pulse wave velocity. These findings suggest that, in healthy young men and women, local heating through ankle-level hot water immersion can improve indices of cardiovascular function both acutely and chronically, alone or combined with exercise training. Further, acute responses may be used to determine an individual’s chronic responsiveness to a heat therapy and/or exercise training intervention. More research in larger, more diverse samples and with a longer duration of therapy and/or training should be conducted to determine if the results are replicable. / Dissertation / Doctor of Philosophy (PhD) / Regular participation in whole-body heat therapy can extend health and life span, but it is used infrequently because of a lack of feasibility from a cost, accessibility, and tolerability standpoint. This thesis explored whether local heat therapy in young healthy men and women would be effective for improving blood vessel health defined as endothelial function and arterial stiffness, both of which are linked to the risk of developing many chronic diseases. Furthermore, the effects of local heat therapy were compared to that of exercise training. We found that there were beneficial short- and long-term effects of lower limb hot water immersion that manifested in different areas of the body. Local heat therapy improved upper limb endothelial function and lower limb arterial stiffness immediately after a session, whereas with repeated exposure, it may have improved central arterial stiffness and cardiorespiratory fitness. Exercise training only had beneficial effects on the blood vessels when combined with heat therapy. Finally, short-term vascular responses can predict long-term vascular responses to both heat therapy and/or exercise training. Overall, our findings suggest that there may be some utility for local heat therapy to promote healthy blood vessels, but more work must be done to replicate our findings and explore its effects on other populations.

ABSTRACT Effect of Warm-Up Activity on Vertical Ground Reaction Forces in Basketball Players During Drop Jump Landings Jacob Hinkel-Lipsker Purpose: The purpose of this study was to examine the effect of certain warm-up activities on vertical ground reaction forces (GRFv) during a drop jump landing. Methods: Eight women and twelve men (mean age 22.6 ± 1.82 years) completed three warm-up activities on three separate days in a counterbalanced order: a passive stretching warm-up, a dynamic warm-up, and a no warm-up control. After completing each activity, participants were asked to perform eight drop jump landings on a force platform. GRFv data was sampled at 1000 Hz during each landing, and the variables analyzed were: peak forefoot and rearfoot magnitude, forefoot and rearfoot rate of loading, and impulse. Results: The dynamic warm-up had significantly greater values (p < 0.05) for forefoot peak magnitude, rearfoot peak magnitude, and forefoot rate of loading compared to the passive stretching and control conditions. Also, there were no significant differences among all activities for rearfoot rate of loading and impulse. Conclusions: The significantly greater values for forefoot peak magnitude, rearfoot peak magnitude, and forefoot rate of loading that the dynamic warm-up produced indicates that this activity may be effective in increasing muscular stiffness in the lower limbs. The failure of the passive stretching warm-up to reach significance indicates that this activity may not be effective in decreasing lower extremity muscular stiffness.

Finite element is used to predict the torsional stiffness and natural frequency response of a FSAE vehicle hybrid chassis, utilizing a carbon fiber reinforced polymer sandwich structure monocoque and a tubular steel spaceframe. To accurately model the stiffness response of the sandwich structure, a series of material tests for different fiber types has been performed and the material properties have been validated by modeling a simple three-point-bend test panel and comparing the results with a physical test. The torsional stiffness model of the chassis was validated with a physical test, too. The stiffness prediction matches the test results within 6%. The model was then used to model the natural frequency response by adding and adjusting the materials’ densities in order to match physical mass properties. A hypothesis is made to explain the failure of the engine mounts under the dynamic response of the frame.

The research presented in this thesis is to evaluate the feasibility of demountable shear connectors as an alternative to welded shear connectors in composite structures through push off tests and composite beam tests. Push off tests were conducted to examine the shear strength, stiffness and ductility of demountable shear connectors in composite structures. The experimental results showed that demountable shear connectors in composite structures have very similar shear capacity to welded shear connectors. The shear capacity was compared against the prediction methods used for the welded shear connections given in Eurocode 4 and AISC 360-10 and the methods used for bolted connections in Eurocode 3 and ACI 318-08. It was found that the AISC 360-10 and ACI 318-08 methods overestimated the shear capacity in some cases. The Eurocode method is conservative and can be utilised to predict the shear capacity of demountable connectors in composite structures. The experimental studies of two identical composite beams using demountable shear connectors and welded shear connectors showed very similar moment capacity. However, the specimen with demountable shear connectors was more ductile compared to the welded specimen. The experimental study suggests that the methods available in Eurocode 4 and BS 5950 for predicting moment capacity and mid span deflection can be adopted for composite beam with demountable shear connectors. In addition, a finite element analysis of push off test and beam test with demountable shear connectors was also conducted for parametric studies and results are used to evaluate the behaviour of composite structures. / EPSRC and the University of Bradford

It is possible to create laminae that have spatially varying fiber orientation with a tow placement machine. A laminate which is composed of such plies will have stiffness properties which vary as a function of position. Previous work had modelled such variable-stiffness laminae by taking a reference fiber path and creating subsequent paths by shifting the reference path. This thesis introduces a method where subsequent paths are truly parallel to the reference fiber path. The primary manufacturing constraint considered in the analysis of variable-stiffness laminates was limits on fiber curvature which proved to be more restrictive for parallel fiber laminae than for shifted fiber. The in-plane responses of shifted and parallel fiber variable-stiffness laminates to either an applied uniform end shortening or in-plane shear were determined. Both shifted and parallel fiber variable-stiffness laminates can redistribute the applied load thereby increasing critical buckling loads compared to traditional straight fiber laminates. The primary differences between the two methods is that parallel fiber laminates are not able to redistribute the loading to the degree of the shifted fiber. This significantly reduces the increase in critical buckling load for parallel fiber variable-stiffness laminates over straight fiber laminates. / Master of Science

In a typical light metal building, the structural members are designed for the forces and moments obtained from the wind drift analysis, which assumes pinned connections at the base. The pinned connections provide no moment at the base and have zero rotational stiffness. However, in reality every connection provides some restraint and has some rotational stiffness. Hence, by considering a modeling assumption of pinned condition, the actual behavior of the connection is not captured and this results in overestimation of lateral drifts and appearance of larger moments at the knee of the gable frames. Since the structural components are designed on the basis of these highly conservative results, the cost of the project increases. This thesis investigates the real behavior of the column base connection and tries to reduce the above stated conservatism by developing a computer program or "wizard" to calculate the initial rotational stiffness of any column base connection. To observe the actual behavior of a column base connection under different load cases, a number of finite element models were created in SAP2000. Each finite element model of the column base connection contained base plate, column stub, anchor bolts and in some cases grout as its components. The model was mainly subjected to three load cases, namely gravity, wind and gravity plus wind. After performing many analyses, the influence of flexibility of each component on the flexibility of the connection was observed and a list of parameters was created. These parameters are the properties of above mentioned components which characterizes any column base connection. These parameters were then used as inputs to model any configuration of the column base connection in the developed wizard. The wizard uses OpenSees and SAP2000 to analyze the modeled configuration of the connection and provides values of the initial rotational stiffness and maximum bearing pressure for the provided loads. These values can be further used in any structural analysis which is done to calculate the lateral drift of a frame under lateral loads. This will also help in getting results which are less conservative than the results which one gets on assuming pinned condition at the base. / Master of Science

Yes / Background: Individuals with lower-limb amputation can use running specific prostheses (RSP) that store and then return elastic energy during stance. However, it is unclear whether varying the stiffness category of the same RSP affects spring-mass behaviour during self-selected, submaximal speed running in individuals with unilateral transtibial amputation. Research question: The current study investigates how varying RSP stiffness affects limb stiffness, running performance, and associated joint kinetics in individuals with a unilateral transtibial amputation. Methods: Kinematic and ground reaction force data were collected from eight males with unilateral transtibial amputation who ran at self-selected submaximal speeds along a 15 m runway in three RSP stiffness conditions; recommended habitual stiffness (HAB) and, following 10-minutes of familiarisation, stiffness categories above (+1) and below (-1) the HAB. Stance-phase centre of mass velocity, contact time, limb stiffness’ and joint/RSP work were computed for each limb across RSP stiffness conditions. Results: With increased RSP stiffness, prosthetic limb stiffness increased, whilst intact limb stiffness decreased slightly (p

In clinical settings, dynamic foot function is commonly inferred from static and passive foot measurements; however, there is little evidence that static foot structure can predict dynamic foot function during walking gait. Previous research seeking to find correlations between the two have focused primarily on sagittal plane midfoot angles even though the midfoot has triplanar motion, which misses potentially important information. Additionally, the focus on kinematics alone may miss the contributions that forces play in midfoot mechanics. To address the angle limitations, a novel Signed Helical Angle (SHA) was developed to capture the triplanar motion of the midfoot from a multi-segment foot model. This was combined with foot segmental force measurements and inverse dynamics to capture dynamic midfoot stiffness. The SHA method and static-dynamic analysis were evaluated on 40 healthy subjects walking at a controlled speed. Subjects were divided into three structural groups based on static arch height (high, normal, low) and stiffness (stiff, normal, flexible). One-way ANOVA was used to evaluate differences among groups in dynamic motion and stiffness and a multiple regression was employed to evaluate relationships across the sample. Calculating the SHA resulted in a greater range of motion (ROM) compared to the sagittal Euler angle commonly used, showing that the motion in the other planes are captured in the SHA. The Finite Helical Axis (FHAx) associated with the SHA also showed that on average the population had a clear distinction between pronation and supination during the stance phase, although individual subjects exhibited substantial variability. While there were visual distinctions in the SHA and the midfoot stiffness among the three stiffness groups and the three arch height groups, the differences were not statistically significant. The only measurement achieving statistical significance was the mean of the sagittal plane midfoot Euler angles among the three AHI groups (p = 0.015); however, this is a postural measure which simply confirms that a high arch will remain high and a low arch will remain low throughout the gait cycle. The lack of any relationships between static foot structure and dynamic foot function, despite advanced modeling and measurements, further confirms that other factors play a large role in foot mechanics. Future studies should focus on evaluating the role of the intrinsic foot musculature (e.g., muscle strength, activation, and redundancy) during gait, and replacing traditional shoe and orthotic recommendations.