In this paper, several new MOSFET devices, vertical MOSFET with L-shaped internal block layers (bVMOS), planar MOSFET with self-aligned internal block layers (bMOS), and Silicon-Germanium MOSFET with self-aligned internal block layers (bSGMOS) are presented. We use the sidewall spacer and etch back techniques to form the L-shaped internal block layers of bVMOS. They can suppress the short channel effects, diminish the parasitic capacitance, and reduce the leakage current cause by P-N junction between source/drain and body regions. They also provide a pass way to eliminate carriers and heat which generated by impact ionization resulting in suppression of floating-body effect and self-heating effect. In addition, we use Si3N4 cap layer upon gate as a hard mask, combining self-aligned and sidewall spacer techniques to fabricate the internal block layers under the both sides of channel end to form bMOS. The depleted region between source/drain and body is shielded and so the short channel effects and the controllability of gate to channel are improved. The internal block layers not only maintain the character of internal block layers but also ameliorate the drawback of bVMOS. The ISE TCAD simulation results show the short channel effect is suppressed and the thermal instability is improved by the internal block layers effectively in each device. Furthermore, we employ the epitaxial silicon-germanium thin film process (bSGMOS) to form silicon-germanium thin film at source/drain region to improve the device current drive by the strain thereby enhancing the device performance.

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DNA is known to be a mechanically and thermally stable structure. In its double stranded form it is densely packed within the cell nucleus and is thermo-resistant up to 70 °C. In contrast, we found a sudden loss of cell nuclei integrity at relatively moderate temperatures ranging from 45 to 55 °C. In our study, suspended cells held in an optical double beam trap were heated under controlled conditions while monitoring the nuclear shape. At specific critical temperatures, an irreversible sudden shape transition of the nuclei was observed. These temperature induced transitions differ in abundance and intensity for various normal and cancerous epithelial breast cells, which clearly characterizes different cell types. Our results show that temperatures slightly higher than physiological conditions are able to induce instabilities of nuclear structures, eventually leading to cell death. This is a surprising finding since recent thermorheological cell studies have shown that cells have a lower viscosity and are thus more deformable upon temperature increase. Since the nucleus is tightly coupled to the outer cell shape via the cytoskeleton, the force propagation of nuclear reshaping to the cell membrane was investigated in combination with the application of cytoskeletal drugs.

Boundary layer rolls are a rather frequent phenomena, where regions of alternating up- and downdraft motion causes clouds to form in elongated, parallel rows oriented with the mean wind direction. The clouds can be seen during certain atmospheric conditions and are often called ”cloud streets” because of their characteristic appearance. By performing a linear instability analysis, the underlying mechanisms causing the onset of boundary layer rolls has been analysed in this study. There are two governing mech- anisms that cause the boundary layer rolls to form, the thermal instability and the dynamic instability. The thermal instability is caused by convection in an unstable airmass, while the dynamic instability usually is associated with neutral or stable conditions. The dynamic instability arise due to an inflection point in the wind profile, around which eddies develop. In a previous study by Svensson et al. (2017), rolls were observed over the Swedish east-coast, stretching out over sea during four days; 2 of May 1997, 3 of May 1997, 17 of May 2011 and 25 of May 2011. The aim of this study is to simulate the rolls on these four dates, analyse the underlying mechanisms and establish what type of instability that primarily causes the rolls to form. The linear stability analysis performed in this study indicate that the dynamic instability is the main mechanism giving rise to the rolls on all four studied dates. The rolls are found to arise over the Swedish mainland and are advected out over the sea. Both the orientation of the rolls and the modeled wind direction are in accordance with the observations. A qualitative agreement is found for the wavelength, the amplitude and the altitude of the rolls, when comparing the results of this study with the observations.

En Astrophysique, la compréhension du processus de formation d'étoiles reste l'une des principales questions. Elle est directement reliée à l'évolution du gaz interstellaire dans les galaxies, et en particulier aux processus de refroidissement et de condensation pour lesquels la turbulence et l'instabilité thermique jouent un rôle dominant. Ce travail se concentre sur l'évolution du gaz atomique et diffus qui fournit les conditions initiales à la formation des nuages moléculaires et se base sur une comparaison étroite entre observations à 21 cm et simulations numériques hydrodynamiques. Pour comprendre les rôles de l'instabilité thermique et de la turbulence dans la transition du gaz chaud (WNM, T ~ 8000 K, n = 0.5 cm-³) vers le gaz froid (CNM, T ~ 80 K, n = 50 cm-³), j'ai produit 90 simulations à basse résolution qui ont permis d'étudier l'influence de la densité initiale du WNM et de la compressibilité du forçage de la turbulence sur l'efficacité de la production de CNM. Un résultat important permet de conclure que le gaz chaud, dans les conditions de turbulence caractéristiques de ce qui est observé, ne transite pas vers le gaz froid quelque soit l'amplitude de la turbulence. Ces simulations à basse résolution ont aussi permis de déterminer quelles conditions initiales permettent de reproduire les propriétés déduites des observations telles que le nombre de Mach, la quantité de CNM en masse ou la dispersion de vitesse turbulente. Un processus de compression, que l'on peut reproduire soit en augmentant la densité initiale du WNM (n ≥ 1.5 cm-³) soit en appliquant un champ de forçage compressif, est nécessaire. Ces conditions initiales ont ensuite été utilisées pour produire deux simulations à haute résolution (1024³) pour lesquelles j'ai montré que les propriétés de la turbulence et de l'instabilité du milieu atomique neutre sont bien reproduites. Les histogrammes de température portent en effet la trace d'un milieu biphasique et les distributions de pression sont semblables aux observations. D'autre part, les spectres de puissance de la densité sont caractéristiques d'un milieu fortement contrasté alors que ceux de la vitesse restent caractéristiques d'une turbulence subsonique. Finalement, les structures froides de ces deux simulations reproduisent les relations masse-échelle et dispersion de vitesse-échelle observées dans les nuages moléculaires, suggérant que la structure des nuages moléculaires pourrait être héritée de celle des nuages de HI à partir desquels ils se sont formés. Le dernier aspect de mon travail est relié à la difficulté rencontrée lors de l'interprétation des données qui n'est possible qu'à partir de grandeurs projetées en deux dimensions. J'ai donc comparé en détails les deux simulations à haute résolution à des observations de cirrus en créant des observations artificielles à 21 cm. Les spectres d'émission et les cartes de densité de colonne ainsi produits sont semblables aux observations. De plus, les simulations donnant accès à l'information en trois dimensions, j'ai étudié les effets de l'auto-absorption dans la création de cartes de densité de colonne à partir de spectres de température de brillance. J'ai conclu de cette étude que l'auto-absorption ne peut être négligée mais qu'elle ne concerne que les lignes de visée les plus brillantes et les plus denses et que la correction habituellement appliquée sur les observations est efficace. Finalement, j'ai appliqué une méthode de décomposition en gaussiennes sur les spectres synthétiques. Cette méthode a pour objectif d'étudier les propriétés de chacune des deux phases thermiques du HI. Les résultats montrent qu'elle est prometteuse pour l'analyse des données de spectro-imagerie à 21 cm, bien que nécessitant des améliorations. Elle permet en effet de bien séparer les phases chaude et froide du milieu atomique et d'en déduire la distribution massique de chacune d'elles. / One of the main current questions in Astrophysics is the understanding of the star formation process, directly related to the processes involved in the cooling and the condensation of the gas yielding to intricate filamentary structures of molecular clouds. Thermal instability and turbulence are playing dominant roles in this complex dynamics. The work presented here is focused on the evolution of the atomic and diffuse interstellar medium that provides the initial conditions to the formation of molecular clouds and is based on the comparison of hydrodynamical numerical simulations and observations. To understand the roles of thermal instability and turbulence in the WNM (warm neutral medium, T ~ 8000 K, n = 0.5 cm-³) to CNM (cold neutral medium, T ~ 80 K, n = 50 cm-³) transition, I produced 90 hydrodynamical numerical simulations of thermally bistable HI and used them to study the impact of the WNM initial density and the compressibility of the turbulent stirring on the efficiency of the CNM production. The main result here is that the warm gas in the observed turbulent conditions do not transit naturally to cold gas whatever the amplitude of turbulent motions. These small resolution simulations also allowed me to determine which initial conditions lead to the reproduction of the observed properties, as the Mach number, the amount of CNM or the amplitude of the turbulent motions. A compression is needed to trigger this transition either by increasing the initial density (n ≥ 1.5 cm-³) or by stirring with a compressive field. These initial conditions have been used to produce two high resolution simulations (1024³). I showed that these two simulations reproduce well the properties of the turbulence and the thermal instability. The temperature histograms present the evidences of a bistable gas and the pressure distributions are in agreement with the observations. On the other hand, the power spectra of the density are characteristic of a high contrasted medium while the power spectra of the velocity remain characteristic of subsonic turbulence. Finally the cold structures of these two simulations reproduce well the mass-size and velocity dispersion-size relations observed in molecular clouds. This suggests that the molecular cloud structure could be inherited from the clouds of atomic gas from which they are born. One of the main limitations in the analysis of observations comes from the fact that it can only be done on integrated quantities in two dimensions. In the last part of my work I compared the two high resolution simulations to observations by creating synthetic 21 cm observations. The emission spectra and column density maps produced in that way are similar to the ones observed. Besides, with the three dimensional informations, I was able to study the effect of the self-absorption in the creation of the column density maps from the brightness temperature spectra. I concluded from this study that the self-absorption cannot be neglected but that it only concerns the brightest and densest lines of sight and that the correction usually applied on observations is efficient. Finally I applied a method of gaussian decomposition on the synthetic spectra. This method has been build to study the properties of each thermal phase in the HI. The results show that it is a highly promising method for the analysis of 21 cm spectro-imaging data even if some improvements are needed. Indeed, it allows a good separation of the cold and warm phases of the atomic medium and a reasonable deduction of the massive distribution of each one.

L’étude du comportement des bétons à hautes températures est d’une grande importance pour déterminer la stabilité et la résistance des structures en béton en situation d’incendie. Des incendies spectaculaires, ces dernières années, ont montré que le béton pouvait être très fortement sollicité. Ainsi il apparaît qu’assurer un très bon comportement du béton en température permet de sauver des vies et de diminuer les frais d'immobilisation et de réparation des structures endommagées. Le travail présenté vise, par une étude expérimentale, à apporter une meilleure compréhension des phénomènes mis en jeu lors de l’exposition aux hautes températures des bétons à hautes performances (BHP). Il s’intéresse, plus particulièrement, aux transferts des fluides dans les bétons (perméabilité) et à l’étude de l’instabilité thermique (phénomène d’éclatement) des bétons à hautes performances. Le travail de thèse a été mené sur des bétons à hautes performances (80 MPa) avec 5% de fumée de silice (matériau à faible perméabilité pour améliorer la durabilité), et différents pourcentages de fibres de polypropylène. L’utilisation des fibres de polypropylène (PP) est considérée comme une solution technique efficace pour améliorer la tenue au feu des bétons à hautes performances, notamment grâce aux phénomènes physiques apparaissant aux températures inférieures à 200°C. Notre travail concerne, dans un premier temps, la caractérisation de l’évolution des propriétés physiques (porosité, perte de masse), thermiques (conductivité et diffusivité) et mécaniques (résistance à la compression et en traction) ainsi que les isothermes de sorption. La deuxième partie de ce travail concerne l’étude de l’évolution de la perméabilité en fonction de la température (jusqu’à 200°C), principale propriété caractérisant les transferts hydriques au sein des bétons. Les paramètres étudiés sont : le type de béton (avec ou sans fibres de PP), deux types de fibre de géométries différentes, la nature du fluide (air ou vapeur d’eau) et la méthode de mesure (en résiduel et à chaud). Les résultats expérimentaux montrent que les fibres génèrent une perméabilité plus importante au-delà de 150°C et que les valeurs obtenues en résiduel ou à chaud peuvent être liés aux modes opératoires. Enfin, dans la dernière partie une investigation sur le phénomène d’éclatement explosif en lien avec la composition du matériau est menée. Une nouvelle méthode d’investigation expérimentale de la sensibilité des formulations à l’instabilité thermique est proposée avec une étude sur des sphères portées en température. Cette méthode devra être comparée aux méthodes traditionnelles d’investigation. L’analyse des résultats des essais permet de discuter sur les causes de l’instabilité thermique et de caractériser les propriétés du béton en température, données indispensables à la modélisation. / The study of the behaviour of concrete at high temperatures is of great importance to determine the stability and strength of concrete structures in fire conditions. Spectacular fires, these last years, showed that the concrete could be very strongly solicited. Thus it appears that to ensure a very good behaviour of the concrete at temperature it is saved people and reduced the expenses of immobilisation and repair of the damaged structures. The aims of the present work, by the experimental study, are to provide a better comprehension of the involved phenomena during the exposure to the high temperatures of the high performance concretes (HPC). It focuses, in particular, on the fluids transfers (permeability) and the study of the thermal instability (spalling) of high performance concrete. The thesis work was conducted on high-performance concrete (80 MPa) with 5% silica fume (low permeability material to improve durability), and different amount of polypropylene fibres. The use of polypropylene fibres (PP) is regarded as an effective technical solution to improve the behaviour of the HPC at fire conditions, in particular thanks to the physical phenomena appearing at the temperatures lower than 200°C. Our work is concerned, initially, on the characterization of the evolution of physical properties (porosity, mass loss), thermal properties (conductivity and diffusivity) and mechanical properties (compressive strength and tensile) and the sorption isotherms. The second part concerns the study of the evolution of the permeability, as a main property characterising the hydrous transfers inside the concrete exposed to temperature. An experimental study is conducted concerning the evolution of the permeability of concrete as a function of temperature (up to 200 ° C). The studied parameters are: the type of concrete (with and without fibres), two types and geometry of fibres, the nature of the fluid (air and vapour) and the measurement methods (residual and under temperature). The experimental results shows that the existing fibres generate a most important permeability beyond 150°C and that the obtained results, by residual or under temperature measurements, may be related to the operating procedures. Finally, in the last part an investigation on the spalling phenomenon related to the material compositions is conducted. A new experimental method of investigation of the sensitivity of the formulations to thermal instability is proposed: the study of spherical specimens exposed in high temperatures. This method will be compared to the traditional methods of investigation. The analysis of the test results makes to discuss the thermal instability causes and to characterize the concrete properties at high temperatures, important data to modelling.

Speed, power and reliability of analogue integrated circuits (IC) exhibit temperature dependency through the modulation of one or several of the following variables: band gap energy of the semiconductor, mobility, carrier diffusion, current density, threshold voltage, interconnect resistance, and variability in passive components. Some of the adverse effects of temperature variations are observed in current and voltage reference circuits, and frequency drift in oscillators. Thermal instability of a voltage-controlled oscillator (VCO) is a critical design factor for radio frequency ICs, such as transceiver circuits in communication networks, data link protocols, medical wireless sensor networks and microelectromechanical resonators. For example, frequency drift in a transceiver system results in severe inter-symbol interference in a digital communications system. Minimum transconductance required to sustain oscillation is specified by Barkhausen’s stability criterion. However it is common practice to design oscillators with much more transconductance enabling self-startup. As temperature is increased, several of the variables mentioned induce additional transconductance to the oscillator. This in turn translates to a negative frequency drift. Conventional approaches in temperature compensation involve temperature-insensitive biasing proportional-to-absolute temperature, modifying the control voltage terminal of the VCO using an appropriately generated voltage. Improved frequency stability is reported when compensation voltage closely follows the frequency drift profile of the VCO. However, several published articles link the close association between oscillation amplitude and oscillation frequency. To the knowledge of this author, few published journal articles have focused on amplitude control techniques to reduce frequency drift. This dissertation focuses on reducing the frequency drift resulting from temperature variations based on amplitude control. A corresponding hypothesis is formulated, where the research outcome proposes improved frequency stability in response to temperature variations. In order to validate this principle, a temperature compensated VCO is designed in schematic and in layout, verified using a simulation program with integrated circuit emphasis tool using the corresponding process design kit provided by the foundry, and prototyped using standard complementary metal oxide semiconductor technology. Periodic steady state (PSS) analysis is performed using the open loop VCO with temperature as the parametric variable in five equal intervals from 0 – 125 °C. A consistent negative frequency shift is observed in every temperature interval (≈ 11 MHz), with an overall frequency drift of 57 MHz. However similar PSS analysis performed using a VCO in the temperature stabilised loop demonstrates a reduced negative frequency drift of 3.8 MHz in the first temperature interval. During the remaining temperature intervals the closed loop action of the amplitude control loop overcompensates for the negative frequency drift, resulting in an overall frequency spread of 4.8 MHz. The negative frequency drift in the first temperature interval of 0 to 25 °C is due to the fact that amplitude control is not fully effective, as the oscillation amplitude is still building up. Using the temperature stabilised loop, the overall frequency stability has improved to 16 parts per million (ppm)/°C from an uncompensated value of 189 ppm/°C. The results obtained are critically evaluated and conclusions are drawn. Temperature stabilised VCOs are applicable in applications or technologies such as high speed-universal serial bus, serial advanced technology attachment where frequency stability requirements are less stringent. The implications of this study for the existing body of knowledge are that better temperature compensation can be obtained if any of the conventional compensation schemes is preceded by amplitude control. / Dissertation (MEng)--University of Pretoria, 2013. / Electrical, Electronic and Computer Engineering / unrestricted