Orientador: José Eduardo Cezar Sampaio / Banca: Rosemary Adriana Chiérici Marcantonio / Banca: Álvaro Francisco Bosco / Banca: Denise Maria Zezel / Banca: Antônio Wilson Sallum / Resumo: O objetivo deste estudo foi avaliar in vitro, a adesão de elementos sanguíneos sobre superfícies radiculares irradiadas com laser de Er:YAG e de Diodo, e a ação destes sobre as superfícies radiculares. Foram obtidas 120 amostras de dentes humanos extraídos por doença periodontal, que foram previamente raspados e aplainados com instrumentos manuais, sendo a seguir divididas aleatoriamente em 6 grupos com 20 amostras cada. O G1 (controle)- não recebeu nenhum tratamento; o G2- recebeu aplicação tópica de EDTA 24%; G3- foi irradiado com laser de Er:YAG com 7,6 J/cm2; o G4- irradiado com laser de Er:YAG com 12,9 J/cm 2; o G5 -irradiado com laser de Diodo com 90 J/cm2 e o G6 - foi irradiado com laser de Diodo com 108 J/cm2. Após a realização dos tratamentos, em 10 amostras de cada grupo foi depositado imediatamente a sua punção, tecido sanguíneo originado da vascularização periférica de humano, sendo que 10 amostras não receberam tal tratamento. Após processamento laboratorial as amostras foram analisadas através de microscopia eletrônica de varredura. As fotomicrografias obtidas foram avaliadas através de dois índices: adesão de elementos sanguineos e de morfologia da superfície radicular e estatisticamente analisadas (Kruskall Wallis e Mann-Whitney). Os resultados demonstraram que em relação a adesão de elementos sanguíneos não houve diferenças estatisticamente significante entre o grupo controle e os tratados com o laser de Er:YAG (p=0,7733 e 0,7831) ; O G5 mostrou-se menos efetivo que o controle na adesão de elementos sanguíneos ( p=0,0305 ) e o G2 foi o menos efetivo de todos na adesão. Com relação a morfologia da superfície radicular houve diferenças significantes entre o controle e os grupos do laser de Er:YAG (p= 0,0001) e entre o G5 do Diodo (0,0259); entre o EDTA e os grupos do laser de Er:YAG (p=0,0150 ) e entre o... (Resumo completo, clicar acesso eletrônico abaixo). / Abstract: The aim of this study was to evaluate in vitro the adhesion of blood components on root surfaces irradiated with Er:YAG and Diode lasers and these lasers effects on root surfaces. It was obtained 120 samples of human teeth extracted by periodontal disease. They were planed and scaled previously with manual instruments and randomly divided into 06 groups of 20 samples each. The groups were treated according to the following procedures: G1 (Control Group) -received no treatment; G2- had a topical application of EDTA 24%; G3- was irradiated with Er:YAG laser (7,6 J/cmø); G4 - was irradiated with Er:YAG laser (12,9 J/cmø); G5 - was irradiated with Diode laser (90 J/cmø) and G6 was irradiated with Diode laser (108 J/cmø). After these treatments were conducted, 10 samples of each group received a stippler, a blood tissue originated from peripheral vascularization, and the reminiscent samples did not receive such treatment. After laboratorial analysis the samples were analyzed through a scanning electronic microscopy. The photomicrographs obtained were evaluated according to adhesion of blood components and morphology of root surface; and statistically analyzed (Kruskall Wallis and Mann-Whitney). With relation to the adhesion of blood components, the results have shown that there were no significant differences between the Control Group and the groups treated with Er:YAG laser (p=0,7733 and 0,7831); G5 was less effective than the Control Group in adhesion of blood components (p=0,0305) and G2 was the least effective of all groups in this case. With relation to the morphology of root surface there were significant differences among the Control Group, the Er:YAG laser groups (p=0,0001) and the Diode laser G5 (p=0,0259); between the EDTA and the Er:YAG laser groups (p=0,0150) and also between the Diode laser G6 and the Er:YAG laser groups (p=0,0032)... (Complete abstract, click electronic address below). / Doutor

Resumo: A raspagem gera smear layer que contém microrganismos e toxinas, podendo interferir no reparo periodontal. Por esse motivo, diferentes substâncias têm sido empregadas para remover esta camada e expor fibras colágenas da superfície dental. A adesão de elementos sangüíneos a superfícies radiculares desmineralizadas e a estabilização do colágeno pelas fibras colágenas são de extrema importância no sucesso da cirurgia periodontal. O objetivo deste estudo foi avaliar os diferentes padrões de adsorção e adesão de elementos sangüíneos a superfícies radiculares quimicamente condicionadas. Setenta e cinco dentes foram raspados, eqüitativamente divididos em 5 grupos: irrigação com água destilada (controle), aplicação de solução de ácido cítrico a 25%, solução de citrato de sódio a 30%, gel de EDTA a 24% e solução de cloridrato de tetraciclina a 50 mg/mL. Metade da superfície condicionada foi exposta a sangue fresco e preparada para microscopia eletrônica de varredura. As superfícies radiculares raspadas e condicionadas com EDTA e ácido cítrico apresentaram os melhores resultados em relação ao grupo controle. O ácido cítrico também se mostrou mais efetivo na remoção de smear layer e na adesão de elementos sangüíneos do que o cloridrato de tetraciclina e o citrato de sódio. Além disso, a relação entre exposição de fibras colágenas e adesão de elementos sangüíneos foi positiva. Dessa forma, o emprego de EDTA e ácido cítrico sobre a superfície radicular aumentam a adsorção e adesão de células sangüíneas e a estabilização da rede de fibrina. / Abstract: Root scaling generates a smear layer which contains microorganisms and toxins that could interfere in periodontal healing. For this reason, different substances have been used to remove it and to expose collagen fibers from tooth surface. Blood elements adhesion to demineralized roots and clot stabilization by collagen fibers are extremely important for the success of periodontal surgery. The aim of this study was to evaluate the different patterns of blood elements adsorption and adhesion to root surfaces chemically conditioned. Seventy five teeth were planed and equitably divided into five groups: irrigation with distilled water (control), application of a 25% citric acid solution, 30% sodium citrate solution, 24% EDTA gel and 50 mg/mL tetracycline hydrochloride. Half of the conditioned surface was exposed to fresh blood and prepared for scanning electron microscopy. Planed root surfaces and conditioned with EDTA and citric acid showed better results when compared to control group. Citric acid was more effective on smear layer removal and blood elements adhesion to root surface than tetracycline and sodium citrate. Also, the relationship between collagen fibers exposure and blood elements adhesion was positive. This way, EDTA and citric acid employment on root surface improve blood element adsorption and adhesion to root surface and fibrin network stabilization. / Orientador: José Eduardo Cezar Sampaio / Coorientador: Letícia Helena Theodoro / Banca: Carlos Rossa Júnior / Banca: Enilson Antonio Sallum / Mestre

Orientador: Luis Roberto Marcondes Martins / Tese (doutorado) - Universidade Estadual de Campinas, Faculdade de Odontologia de Piracicaba / Made available in DSpace on 2018-08-13T11:40:25Z (GMT). No. of bitstreams: 1 SantosFilho_PauloCesardeFreitas_D.pdf: 10660151 bytes, checksum: bd3f67697b369623400074dcf22ec01c (MD5) Previous issue date: 2009 / Resumo: O objetivo deste estudo foi desenvolver protocolo de modelagem tridimensional para incisivo central superior com aplicabilidade ao método de elementos finitos e avaliar o comportamento biomecânico de incisivo superior tratado endodonticamente e restaurado com retentores e coroa cerâmica por meio de análise por elementos finitos comparado ao dente hígido. Para geração do modelo 3D foi selecionado incisivo central superior hígido. Esmalte e dentina foram degradados em diferentes fases com ácido clorídrico-10%, e mapeados com scanner de contato 3D (Modela, Roland). Para o mapeamento do volume pulpar, a dentina foi seccionada longitudinalmente no sentido mesio-distal e realizado o escaneamento do espaço negativo referente à polpa. Os arquivos *.STL foram exportados para programa Bio-CAD (Rhinoceros-3D). Volumes de cada estrutura dental e técnicas restauradoras foram gerados por meio da associação de superfícies NURBS. Os modelos foram exportados para o programa de elementos finitos (FEMAP-NeiNastran), onde foi realizado o processo de malhagem, inserção das propriedades mecânicas e condições de contorno. Foram gerados 17 modelos, sendo um do dente hígido e 16 modelos de acordo com os 4 fatores em estudo: tipo de retentor em dois níveis: pino de fibra de vidro (PFV) e núcleo moldado fundido (NMF), extensão do retentor em dois níveis: 7,0mm (7,0) e 12,0mm (12,0), remanescente coronário em dois níveis: remanescente de 2,0mm (RE) e ausência de remanescente (ARE), enfraquecimento do canal radicular em dois níveis: ausência de enfraquecimento (AENF) e presença de enfraquecimento (ENF). Foi simulada aplicação de pressão constante no valor de 100N perpendicularmente à superfície palatina do incisivo. Os resultados foram analisados pelo critério de von Mises e tensão máxima principal. Os resultados obtidos mostraram que o modelo geométrico 3D desenvolvido é adequado para a análise por elementos finitos. Concluiu-se que o PFV apresenta distribuição homogênea das tensões mais semelhante ao dente hígido, enquanto o NMF apresentou grande concentração de tensão no interior do canal radicular. O fator extensão do retentor intra-radicular influenciou isoladamente apenas a distribuição de tensões do NMF. A presença de remanescente coronário sempre melhorou a distribuição de tensões. O enfraquecimento do canal radicular teve maior impacto na distribuição de tensões. / Abstract: The aim of this study was develop 3D model generation protocol for upper anterior teeth for finite element analysis and evaluate biomechanical behavior of endodontically treated incisor with finite element analysis compared to sound teeth. It was selected intact upper central incisor. Enamel and dentin were treated in different steps with cloridric acid 2% and scanned with 3D-contact scanner. The stereolithographics archives were exported to Bio CAD program. The volums of each dental structure and restorative techniques were generated by association of NURBS surfaces. The models were exported for finite element software, where were realized the meshed process, mechanical properties insertion and bondary conditions. It were generated 17 models, one was a sound incisor model and 16 models according to 4 studied factors: post type: glass fiber post (GFP) and cast post and core (CPC), post length: 7,0mm (7,0) e 12,0mm (12,0), ferrule: 2,0mm ferrule (FE) and absence of ferrule (AFE), weakness of root canal: absence of weakness (AWR) and weakened root (WR). It was simulated 100N loading application on the palatal surface with 135° angulation. The results were analised by Von Mises criteria and principal maximum tension. Obtained results showed that geometric model developed is appropriated for finite element analysis. It can be concluded that GFP showed homogeneous stress distribution like the sound incisor, while CPC showed stress concentration into root canal. The post length influenced only the CPC stress distribution. The ferrule always showed better stress distribution. The weakness of root showed the highest impact in stress distribution. / Doutorado / Dentística / Doutor em Clínica Odontológica

Durch neue, hochflexible Fertigungsverfahren wie das Freiformfräsen eröffnet sich für Kegelradverzahnungen ein großes geometrisches Optimierungspotenzial. Diese Arbeit widmet sich daher der Ermittlung einer optimalen Makro-, Mikro- und Zahnfußgeometrie für bogenverzahnte Kegelräder. Neben dem Zahnprofil und der Zahnfußkurve wird besonderes Augenmerk auf die Ermittlung topologischer Flankenmodifikationen zur Maximierung der Tragfähigkeit gelegt. Gleichzeitig bietet der gezeigte Optimierungsalgorithmus die Möglichkeit zur Minimierung der Geräuschanregung, wodurch der bisher existierende Zielkonflikt zwischen diesen beiden Aspekten aufgehoben werden kann.

Planetengetriebe zeichnen sich aufgrund der Leistungsverzweigung durch eine hohe Leistungsdichte und kompakte Bauweise bei koaxialer Drehmomentweiterführung aus. Ihre Anwendung überspannt verschiedene Einsatzgebiete, so zum Beispiel hochpräzise Roboterantriebe, Leistungsindustriegetriebe, Windenergieanlagen sowie sicherheitsrelevante mechatronische Module im Antriebsstrang der Luft- und Raumfahrttechnik. Eine sichere Berechnungsgrundlage ist deshalb zur Prozesssicherheit, Wettbewerbsfähigkeit und Ressourcenschonung von hoher Bedeutung. Planetenräder, welche direkt auf dem Planetenbolzen gelagert sind, können als Zahnkranz ausgeführt werden. In Abhängigkeit von Kranzdicke und -durchmesser ändert sich die Kranzelastizität und damit verbunden auch die Zahnfußbeanspruchung. Folglich können Zahnkränze nicht zwangsläufig mit den gleichen Vorschriften wie Vollräder berechnet werden. In einigen internationalen und nationalen Arbeiten sind schon theoretische Grundlagenuntersuchungen zur Beanspruchungscharakteristik elastischer Außenverzahnungen durchgeführt worden. Unter Umständen kann es zu einer Verlagerung des Zugspannungsmaximums in einen Bereich außerhalb des betrachteten Zahneingriffs kommen. Die Betrachtungen zur Zahnfußbeanspruchung können also nicht auf die Lastzähne beschränkt bleiben, sondern müssen analog zur Innenverzahnung mit elastischem Kranz am gesamten Umfang betrachtet werden. Der als Zahnkranz ausgeführte Planet erfährt neben den Belastungen durch die Zahnkräfte auch Zwänge durch Umgebungsgeometrie und Drehbewegung. Die Anteile der einzelnen Einflüsse aus Kraft- und Momenteneinleitungen an den Lastzähnen, der Lastreaktionen aus der Lagerung sowie Lasteinleitungen durch Fliehkräfte sind stark abhängig von der Elastizität des Kranzes und der Getriebekinematik. Ziel der theoretischen Untersuchungen der vorliegenden Arbeit ist die Erstellung eines detaillierten, analytischen und geschlossen lösbaren Berechnungsganges bezüglich der Zahnfußtragfähigkeit. Des Weiteren wird eine Berechnungsmethode, basierend auf numerisch ermittelten Kerbspannungen, entwickelt. Mittels ausgewählter experimenteller Untersuchungen durch Dauerfestigkeitsversuche und quasistatische Messversuche mit Dehnungsmessstreifen in der Zahnfußausrundung soll der ermittelte Berechnungsgang praxisnah überprüft werden.:Formelzeichenverzeichnis XI 1. Einleitung und Problemstellung 1 2. Stand des Wissens 3 2.1. Grundlagen zu Zahnradgetrieben 3 2.1.1. Historischer Abriss 3 2.1.2. Typische Verzahnungsschäden im Betrieb 5 2.1.3. Historische Entwicklung der Berechnung der Zahnfußtragfähigkeit 9 2.2. Normative Berechnungsverfahren zur Zahnfußtragfähigkeit von außenverzahnten Stirnradgetrieben 12 2.3. Historie des Forschungsstandes zu elastischen Verzahnungen 14 3. Analyse des Systems elastisches Planetenrad 21 3.1. Belastung und Beanspruchung im Zahnfuß 21 3.2. Planetenlagerreaktion 23 3.3. Fliehkrafteinfluss 26 4. Entwicklung eines angepassten Tragfähigkeitsnachweises 31 4.1. Beanspruchungsermittlung unter Nutzung numerischer Methoden 31 4.1.1. Beschreibung der Zahngeometrie 32 4.1.2. Lasten und Randbedingungen 43 4.1.3. Besondere Anforderungen an das FE-Modell 46 4.1.4. Sensitivitätsanalyse 47 4.1.5. Auswertung der ermittelten Beanspruchungen 49 4.1.6. Berechnung der Doppelamplituden und Mittelspannung der Zahnfußbeanspruchung 51 4.2. Beanspruchungsermittlung unter Nutzung analytischer Methoden 51 4.2.1. Bestimmung der Zahnbiegenennspannung 52 4.2.2. Bestimmung der Kranznennspannung infolge der angreifenden Zahnkräfte 52 4.2.3. Bestimmung der Kranznennspannung infolge der Fliehkräfte 57 4.2.4. Lösung der statisch unbestimmten Größen 59 4.2.5. Analytische Berechnung der Ringdeformation 62 4.2.6. Ermittlung des versteifenden Einflusses der Verzahnung 63 4.2.7. Spannungskorrekturfaktoren 64 4.2.8. Berechnung der Doppelamplitude und Mittelspannung der Zahnfußbeanspruchung 67 4.3. Beanspruchbarkeitsermittlung 71 4.3.1. Ermittlung der Dauerfestigkeit bei allgemein wechselnder Beanspruchung 71 4.3.2. Ermittlung der zulässigen Zahnfußspannung 73 4.4. Berechnung der Tragfähigkeit 74 4.4.1. Grenzen und Einschränkungen 75 4.4.2. Lokaler Nachweis 75 4.4.3. Nennspannungsnachweis 76 5. Methodenträger 79 6. Experimentelle Untersuchungen 83 6.1. Versuche zur lokalen Zahnfußbeanspruchung 83 6.1.1. Prüfstandsaufbau 83 6.1.2. Versuchsdurchführung 87 6.1.3. Auswertung der Messergebnisse 90 6.1.4. Vergleich mit FE-Resultaten 96 6.2. Versuche zur Tragfähigkeitsberechnung 99 6.2.1. Prüfstandsaufbau 99 6.2.2. Angewandte Verfahren zur Durchführung und Auswertung der Ermüdungsversuche 103 6.2.3. Ermittlung von grundlegenden Versuchsparametern 103 6.2.4. Versuchsdurchführung und Dokumentation 105 6.2.5. Auswertung der Versuchsergebnisse 108 7. Zusammenfassung und Ausblick 117 Abbildungsverzeichnis 121 Tabellenverzeichnis 124 Literaturverzeichnis 127 A. Anhang 135 A.1. Berechnungsbeispiel erweiterte Zahnfußtragfähigkeitsberechnung 137 A.2. Alternative Berechnung der Schnittreaktionen für die Lagerreaktion als Einzellasten 149 A.3. Gleichungen zur analytischen Berechnung der Kranzdeformation 151 A.4. Unterlagen quasistatischer Planetengetriebeprüfstand 155 A.4.1. Verzahnungsdaten Prüfstand 155 A.4.2. Datenblatt DMS-Ketten Zahnfuß 156 A.4.3. Konturscans Zahnlücke 157 A.4.4. Zusammenbauzeichnung Prüfstand 161 A.4.5. Zeichnungen Planetenräder 162 A.5. Unterlagen Zwischenradprüfstand 171 A.5.1. Verzahnungsdaten Prüfstand 171 A.5.2. Konturscans Zahnlücke 172 A.5.3. Versuchsdaten 174 A.5.4. Ermittlung der Werkstoffkennwerte 181 A.5.5. Werkstoffuntersuchungen 182 A.5.6. Zusammenbauzeichnung Prüfstand 186 A.5.7. Schnittdarstellung Prüfgetriebe 187 A.5.8. Schnittdarstellung Rückgetriebe 188 A.5.9. Zeichnungen Prüfritzel 189 A.5.10. Zeichnungen Gegenräder 193 / Due to the power split, planetary gearboxes are characterised by a high power density and compact design at coaxial torque transmission. Their application ranges across various fields of use, such as high-precision robot drives, industrial gearboxes, wind turbines, and safetyrelevant mechatronic modules in the drive trains of aerospace systems. A reliable calculation method is therefore of great importance for process reliability, competitiveness and resource efficiency. Planet gears that are beared directly on the planet carrier pin can be designed as a gear rim. Depending on the rim thickness and diameter, the rim elasticity and the tooth root stress changes. Therefore, rims cannot be calculated with the same standards as solid gears. Theoretical research on the stress characteristics of elastic external gears has already been conducted in several international and national papers. Under certain circumstances, a shift of the tensile stress maximum to a region outside the considered tooth meshing is possible. The evaluation of the tooth root stress can therefore not be limited to the loaded teeth but must be expanded to the entire circumference analogous to the internal gearing with elastic rim. The planet designed as a gear rim experiences constraints due to surrounding geometry and rotational movement in addition to the tooth loads. The proportions of the individual influences from force and moment inputs at the load teeth, the load reactions from the bearing as well as load inputs through centrifugal forces are strongly dependent on the elasticity of the ring and the kinematics of the gear. The purpose of the theoretical investigations of the thesis at hand is the creation of a detailed, analytical and closed solvable calculation procedure regarding the tooth root loadcarrying capacity. Furthermore, a calculation method based on numerically determined tooth root stresses is developed. By means of selected experimental investigations through fatigue strength tests and quasi-static measurement tests with strain gauges in the tooth root fillet, the determined calculation procedure is to be verified in a practically oriented manner.:Formelzeichenverzeichnis XI 1. Einleitung und Problemstellung 1 2. Stand des Wissens 3 2.1. Grundlagen zu Zahnradgetrieben 3 2.1.1. Historischer Abriss 3 2.1.2. Typische Verzahnungsschäden im Betrieb 5 2.1.3. Historische Entwicklung der Berechnung der Zahnfußtragfähigkeit 9 2.2. Normative Berechnungsverfahren zur Zahnfußtragfähigkeit von außenverzahnten Stirnradgetrieben 12 2.3. Historie des Forschungsstandes zu elastischen Verzahnungen 14 3. Analyse des Systems elastisches Planetenrad 21 3.1. Belastung und Beanspruchung im Zahnfuß 21 3.2. Planetenlagerreaktion 23 3.3. Fliehkrafteinfluss 26 4. Entwicklung eines angepassten Tragfähigkeitsnachweises 31 4.1. Beanspruchungsermittlung unter Nutzung numerischer Methoden 31 4.1.1. Beschreibung der Zahngeometrie 32 4.1.2. Lasten und Randbedingungen 43 4.1.3. Besondere Anforderungen an das FE-Modell 46 4.1.4. Sensitivitätsanalyse 47 4.1.5. Auswertung der ermittelten Beanspruchungen 49 4.1.6. Berechnung der Doppelamplituden und Mittelspannung der Zahnfußbeanspruchung 51 4.2. Beanspruchungsermittlung unter Nutzung analytischer Methoden 51 4.2.1. Bestimmung der Zahnbiegenennspannung 52 4.2.2. Bestimmung der Kranznennspannung infolge der angreifenden Zahnkräfte 52 4.2.3. Bestimmung der Kranznennspannung infolge der Fliehkräfte 57 4.2.4. Lösung der statisch unbestimmten Größen 59 4.2.5. Analytische Berechnung der Ringdeformation 62 4.2.6. Ermittlung des versteifenden Einflusses der Verzahnung 63 4.2.7. Spannungskorrekturfaktoren 64 4.2.8. Berechnung der Doppelamplitude und Mittelspannung der Zahnfußbeanspruchung 67 4.3. Beanspruchbarkeitsermittlung 71 4.3.1. Ermittlung der Dauerfestigkeit bei allgemein wechselnder Beanspruchung 71 4.3.2. Ermittlung der zulässigen Zahnfußspannung 73 4.4. Berechnung der Tragfähigkeit 74 4.4.1. Grenzen und Einschränkungen 75 4.4.2. Lokaler Nachweis 75 4.4.3. Nennspannungsnachweis 76 5. Methodenträger 79 6. Experimentelle Untersuchungen 83 6.1. Versuche zur lokalen Zahnfußbeanspruchung 83 6.1.1. Prüfstandsaufbau 83 6.1.2. Versuchsdurchführung 87 6.1.3. Auswertung der Messergebnisse 90 6.1.4. Vergleich mit FE-Resultaten 96 6.2. Versuche zur Tragfähigkeitsberechnung 99 6.2.1. Prüfstandsaufbau 99 6.2.2. Angewandte Verfahren zur Durchführung und Auswertung der Ermüdungsversuche 103 6.2.3. Ermittlung von grundlegenden Versuchsparametern 103 6.2.4. Versuchsdurchführung und Dokumentation 105 6.2.5. Auswertung der Versuchsergebnisse 108 7. Zusammenfassung und Ausblick 117 Abbildungsverzeichnis 121 Tabellenverzeichnis 124 Literaturverzeichnis 127 A. Anhang 135 A.1. Berechnungsbeispiel erweiterte Zahnfußtragfähigkeitsberechnung 137 A.2. Alternative Berechnung der Schnittreaktionen für die Lagerreaktion als Einzellasten 149 A.3. Gleichungen zur analytischen Berechnung der Kranzdeformation 151 A.4. Unterlagen quasistatischer Planetengetriebeprüfstand 155 A.4.1. Verzahnungsdaten Prüfstand 155 A.4.2. Datenblatt DMS-Ketten Zahnfuß 156 A.4.3. Konturscans Zahnlücke 157 A.4.4. Zusammenbauzeichnung Prüfstand 161 A.4.5. Zeichnungen Planetenräder 162 A.5. Unterlagen Zwischenradprüfstand 171 A.5.1. Verzahnungsdaten Prüfstand 171 A.5.2. Konturscans Zahnlücke 172 A.5.3. Versuchsdaten 174 A.5.4. Ermittlung der Werkstoffkennwerte 181 A.5.5. Werkstoffuntersuchungen 182 A.5.6. Zusammenbauzeichnung Prüfstand 186 A.5.7. Schnittdarstellung Prüfgetriebe 187 A.5.8. Schnittdarstellung Rückgetriebe 188 A.5.9. Zeichnungen Prüfritzel 189 A.5.10. Zeichnungen Gegenräder 193

No description available.

Indiana University-Purdue University Indianapolis (IUPUI) / Introduction: Regenerative endodontic procedures are an effective treatment option for immature teeth with infected necrotic pulps to allow for healing and potential continued root development, yet challenges to ideal treatment outcomes remain. Consistent development of root length and width of dentin remains a challenge, as does development of the pulp-dentin complex. Previous in vitro studies have assessed the role of different growth factors and bioactive molecules in combination with scaffolds to potentially facilitate continued development of the pulp-dentin complex using dental pulp stem cells (DPSCs). The proline-rich tyrosine kinase 2 (Pyk2) is linked with osteoblast activity and the regulation of bone mass. Further, the Pyk2 inhibitor PF-4618433 (PF-46) has been shown in previous studies to enhance osteoblast activity and mineral deposition in vitro. However, whether Pyk2 targeting promotes the osteogenic differentiation of DPSCs remains unknown. Objective: The purpose of this study was to investigate the effect of a Pyk2 inhibitor, PF-46, on the proliferation, differentiation, and mineralization of human DPSCs. Materials and Methods: Human DPSCs were cultured in 24-well plates with α-MEM with 10% FBS, and containing 0 μM (vehicle control) or 0.1 μM, 0.3 μM, or 0.6 μM PF-46. Fresh media and treatments were replaced every 2-3 days. After 1 day incubation, cytotoxic effects were evaluated by using an MTS proliferation assay. After 4 days of treatment, direct cell counting was performed. To induce osteogenic differentiation, ascorbic acid and β-glycerol phosphate were added to the culture media and the DPSCs were cultured with PF-46 for 14 days. Then, an alkaline phosphatase (ALP) assay and mineral deposition assay were performed. Differences between treatment groups were analyzed by a one-way ANOVA followed by pair-wise tests conducted using Tukey’s multiple comparisons procedure with a 5% significance level. Results: The 0.6 μM PF-46 group had a significantly higher cell count, ALP activity and mineral deposition when compared to 0 μM PF-46. The 0.1 and 0.3 μM PF-46 groups also had significantly higher ALP activity compared to the 0 μM PF-46 group after 14 days of incubation. There was a general trend of increased differentiation and mineral deposition as the concentration of PF-46 increased from 0.1 μM to 0.6 μM. Conclusion: There was a general concentration-dependent increase in cell count, differentiation, and mineral deposition by human DPSCs as the concentration of PF-46 increased from 0 μM up to 0.6 μM, with the highest activity observed with 0.6 μM PF-46. Although further research is needed, these results suggest that strategies that target Pyk2 may potentially be used to improve the osteogenic differentiation of DPSCs to aid endodontic regeneration.

Schneckenradgetriebe sind aufgrund ihrer Verzahnungsgeometrie prädestiniert für Getriebeanwendungen mit diskontinuierlichem und schwingungsbehaftetem Betrieb. Bei hohen Momenten und geringen Drehzahlen stellt dabei die Zahnfußtragfähigkeit die primäre Auslegungsgrenze dar. Das Ziel der vorliegenden Arbeit lag in der Erhöhung der Genauigkeit der Berechnungsmethoden für die Zahnfußtragfähigkeit von Schneckenrädern, auch zur Steigerung des Volumennutzwertes dieser Getriebe. Hierzu wurden alle die Tragfähigkeit des Zahnfußes beeinflussenden Parameter durch eine Vielzahl von Experimenten und FE Simulationen untersucht. Dies schließt eine genaue Analyse der Geometrie von Schneckengetrieben, deren Fertigung und Einbausituation, die verwendeten Werkstoffe und deren Beanspruchung mit ein. Auf dieser Basis gelang neben der Entwicklung eines vergleichsspannungsbasierten analytischen Berechnungsverfahrens die Erstellung eines örtlichen Berechnungskonzeptes nach dem Kerbspannungskonzept. Hiermit konnte die Einschätzung der Zahnfußtragfähigkeit bei der Neuentwicklung und die Optimierung von Getrieben verbessert werden. / Worm gears are well suited for gearbox applications in environments with discontinuous conditions and mechanical vibrations. In the case of high torque and low speed, the tooth root strength is the primary design limit. The aim of the present paper is to improve the accuracy of the calculation methods for the tooth root strength of worm wheels. To reach this, all parameters which affects the strength of the tooth root were examined. This includes the geometry, the manufacturing, the materials and the stresses of worm wheels. Through this investigation, the development of a new analytical calculation method based on the equivalent stress concept could be done. Furthermore, a local calculation method based on the notch stress concept was developed. Thus, the forecast of the tooth root strength of worm wheels for redevelopment and optimization could be improved.

Indiana University-Purdue University Indianapolis (IUPUI) / Accurate determination of working length during endodontic therapy is a crucial step in achieving a predictable outcome. This is determined by the use of electronic apex locators, tactile perception, and knowledge of average tooth lengths and/or dental radiography whether digital or conventional is utilized. It is the aim of this study to determine if there is a difference between Schick digital radiography and Kodak Insight conventional film in accurately determining working lengths when modifying exposure time and source-film/sensor distance. Twelve teeth with size 15 K-flex files at varying known lengths from the anatomical apex were mounted in a resin-plaster mix to simulate bone density. Each tooth was radiographed while varying the source-film/sensor distance and exposure 122 time. Four dental professionals examined the images and films independently. Ten images and 10 films were selected at random and re-examined to determine each examiner?s repeatability. The error in working length was calculated as the observed value minus the known working length for each tooth type. A mixed-effects, full-factorial analysis of variance (ANOVA) model was used to model the error in working length. Included in the ANOVA model were fixed effects for type of image, distance, exposure time, and all two-way and three-way interactions. The repeatability of each examiner for each film type was assessed by estimating the intra-class correlation coefficient (ICC). The repeatability of each examiner on digital film was good with ICCs ranging from 0.67 to 1.0. Repeatability on the conventional film was poor with ICCs varying from -0.29 to 0.55.We found there was an overall difference between the conventional and digital films (p < 0.001). After adjusting for the effects of distance and exposure time, the error in the working length from the digital image was 0.1 mm shorter (95% CI: 0.06, 0.14) than the error in the working length from the film image. There was no difference among distances (p = 0.999) nor exposure time (p = 0.158) for film or images. Based on the results of our study we conclude that although there is a statistically significant difference, there is no clinically significant difference between digital radiography and conventional film when exposure time and source-film/sensor distance are adjusted.

Indiana University-Purdue University Indianapolis (IUPUI) / Accurate determination of working length during endodontic therapy is critical in achieving a predictable and successful outcome. Working length is determined by the use of electronic apex locators, tactile perception, knowledge of average tooth lengths and dental radiography. Due to the increasing use of digital radiography in clinical practice, a comparison with conventional film in working length determination is justified. The purpose of this study is to determine if there is a difference between Schick digital radiography and Kodak Ultra-speed film in the accurate determination of working lengths when vertical angulation of the object is variable. Twelve teeth with #15 K-flex files at varying known lengths from the anatomical apex were mounted in a resin-plaster mix to simulate bone density. A mounting jig for the standardization of projection geometries allowed for exact changes in vertical angulation as it related to the object (tooth) and the film/sensor. Each tooth was imaged using Schick CDR and Kodak Ultra-speed film at varying angles with a consistent source-film distance and exposure time. Four dental professionals examined the images and films independently and measured the distance from the tip of the file to radiographic apex and recorded their results. The error in working length was calculated as the observed value minus the known working length for each tooth type. A mixed-effects, full-factorial analysis of variance (ANOVA) model was used to model the error in working length. Included in the ANOVA model were fixed effects for type of image, vertical angulation, and the interaction of angle and film type. Tooth type and examiner were included in the model as random effects assuming a compound symmetry covariance structure. The repeatability of each examiner, for each film type, was assessed by estimating the intra-class correlation coefficient (ICC). The ICC was determined when 12 randomly selected images and radiographs were reevaluated 10 days after initial measurements. The repeatability of each examiner for Schick CDR was good with ICCs ranging from 0.67 to 1.0. Repeatability for the conventional film was poor with ICCs varying from -0.29 to 0.55. We found the error in the working length was not significantly different between film types (p = 0.402). After adjusting for angle, we found that error in the working length from the digital image was only 0.02 mm greater (95-percent CI: -0.03, 0.06) than the conventional film. Furthermore, there was not a significant difference among the angles (p = 0.246) nor in the interaction of image type with angle (p = 0.149). Based on the results of our study, we conclude that there is not a statistically significant difference in determining working length between Schick CDR and Kodak Ektaspeed film when vertical angulation is modified.